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The International Journal of Cardiovascular Imaging

Erschienen in:

25.06.2022 | Original Paper

Alterations in right ventricular mechanics in patients with Behcet’s disease

verfasst von: Lale Dinc Asarcikli, Fatih Saritas, Tolga Sinan Guvenc, Fatma Can, Sena Sert, Rengin Cetin Güvenc, Esra Poyraz, Sennur Unal

Erschienen in: The International Journal of Cardiovascular Imaging | Ausgabe 11/2022

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Abstract

Manifest myocardial involvement is somewhat rare in patients with Behcet’s disease (BD), although echocardiographic studies suggest that subclinical alterations in left ventricular (LV) contractility is rather common. Data on right ventricular (RV) involvement in BD is rather scarce. This study aims to determine whether RV systolic performance is affected in BD patients, and to understand the clinical and echocardiographic correlates of RV contractility in these patients. Forty-five patients who fulfilled criteria for BD and 45 age and gender matched controls were enrolled. All participants underwent a comprehensive echocardiographic examination, including deformation imaging, to characterize RV mechanics. Conventional morphologic and echocardiographic indicators of RV morphology and function were not different between groups, but RV apical strain and RV free wall strain (FWS) were significantly lower in BD patients as compared to the controls (P < 0.001 and P = 0.02, respectively). The only significant correlates of FWS were tricuspid regurgitation velocity and related indices in healthy controls, while FWS correlated with LV global longitudinal strain (GLS), morphologic measures of left and right atria and ventricles, and with conventional measures of right ventricular contractility. The relationship between FWS and GLS remained statistically significant after adjusting for other clinical and echocardiographic parameters (β = 0.379, P = 0.01). In patients with BD, there is a subclinical alteration in RV contractility and the degree of alteration in the RV systolic performance paralleled that of LV. Thus, present results support the presence of RV involvement in these patients.

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Titel: Alterations in right ventricular mechanics in patients with Behcet’s disease
verfasst von: Lale Dinc Asarcikli
Fatih Saritas
Tolga Sinan Guvenc
Fatma Can
Sena Sert
Rengin Cetin Güvenc
Esra Poyraz
Sennur Unal
Publikationsdatum: 25.06.2022
Verlag: Springer Netherlands
Erschienen in: The International Journal of Cardiovascular Imaging / Ausgabe 11/2022
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI: https://doi.org/10.1007/s10554-022-02664-2

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