Erschienen in:
17.08.2022 | ASO Author Reflections
ASO Author Reflections: Significance of Loss of Skeletal Muscle Mass During Neoadjuvant Chemotherapy in Older Patients with Esophageal Cancer
verfasst von:
Tsuyoshi Harada, MSc, Tetsuya Tsuji, MD, PhD, Takeo Fujita, MD, PhD, FACS
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 13/2022
Einloggen, um Zugang zu erhalten
Excerpt
The number of older patients with esophageal cancer has increased globally,
1 necessitating development of novel treatments and supportive care for patients 65 years of age or older with esophageal cancer who have physical frailty and a heterogeneous aging process.
2 Skeletal muscle mass (SMM) affects progression of the physical frailty, general health, and prognosis of older patients with cancer.
3 Findings recently have shown that loss of SMM during neoadjuvant therapy affects the prognosis of individuals with locally advanced esophageal cancer.
4 However, information regarding this phenomenon in older patients is limited. …