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Erschienen in: Archives of Gynecology and Obstetrics 5/2012

01.11.2012 | Maternal-Fetal Medicine

Assessment of maternal serum sialic acid levels in preterm versus term labor: a prospective-controlled clinical study

verfasst von: Mete Gurol Ugur, Naciye Kurtul, Ozcan Balat, Melek Ekici, Seval Kul

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 5/2012

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Abstract

Purpose

To compare total serum sialic acid (SA) levels between singleton pregnant women diagnosed with preterm labor between 24th and 36th weeks of pregnancy, singleton pregnant women at term, and their gestational age-matched controls.

Methods

Thirty pregnants diagnosed with preterm labor (group I), 30 gestational age-matched control pregnants (group II), 30 pregnants with labor at term (group III), and 30 gestational age-matched control pregnants (group IV) were enrolled. Detailed history, demographic data (age, gravidity, parity, abortion), ultrasound parameters, cervical dilatation and effacement, fetal tococardiography, routine laboratory tests, and total SA levels were assessed.

Results

There was no statistically significant difference between the parameters other than SA. SA levels of the preterm labor group (group I) were significantly higher than the other three groups.

Conclusions

We may suggest that pathways including SA or molecules containing SA in subclinical infection without the clinical manifestations of apparent infection may be involved in the pathogenesis of preterm birth. Future longitudinal studies are needed to investigate prediction performance and to better understand the role of SA in molecular mechanisms leading to preterm labor.
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Metadaten
Titel
Assessment of maternal serum sialic acid levels in preterm versus term labor: a prospective-controlled clinical study
verfasst von
Mete Gurol Ugur
Naciye Kurtul
Ozcan Balat
Melek Ekici
Seval Kul
Publikationsdatum
01.11.2012
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 5/2012
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-012-2423-2

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