Introduction
Data and methods
Research object
Data collection
Statistical methods
Results
General description of the research object
Variable | Control (n = 1175) | T2DM (n = 1163) | CAD (n = 982) | Comorbidity (n = 504) |
---|---|---|---|---|
Age
| 40.79 ± 14.02 | 59.98 ± 12.06 | 67.16 ± 11.75 | 67.65 ± 10.38 |
Sex
| ||||
Male | 726 (61.79) | 635 (54.60) | 641 (65.27) | 312 (61.90) |
Female | 449 (38.21) | 528 (45.40) | 341 (34.73) | 192 (38.10) |
Area
| ||||
Rural | 29 (2.47) | 447 (38.44) | 378 (38.49) | 142 (28.17) |
Suburban | 48 (4.09) | 187 (16.08) | 114 (11.61) | 90 (17.86) |
Urban | 1098 (93.45) | 529 (45.59) | 490 (49.90) | 272 (53.97) |
Education
| ||||
illiteracy | 8 (0.68) | 92 (7.91) | 95 (9.67) | 44 (8.73) |
Primary, middle, high, technical secondary school | 259 (22.04) | 936 (80.48) | 812 (82.69) | 418 (82.94) |
College, bachelor, master degree or above | 908 (77.28) | 135 (11.61) | 75 (7.64) | 42 (8.33) |
Marriage
| ||||
Married | 853 (72.60) | 1099 (94.50) | 949 (96.64) | 482 (95.63) |
Unmarried, divorced, widowed | 322 (27.40) | 64 (5.50) | 33 (3.36) | 22 (4.37) |
Occupation
| ||||
Agriculture and forestry | 62 (5.28) | 368 (31.64) | 270 (27.49) | 120 (23.81) |
Business services | 56 (4.77) | 166 (14.27) | 62 (6.31) | 30 (5.95) |
Military, national party | 785 (66.81) | 137 (11.78) | 123 (12.53) | 61 (12.10) |
Students | 68 (5.79) | 4 (0.34) | 1 (0.10) | 1 (0.20) |
Others | 204 (17.36) | 488 (41.96) | 526 (53.56) | 292 (57.94) |
FHx of DM
| ||||
No | 1022 (86.98) | 938 (80.65) | 943 (96.03) | 440 (87.30) |
Yes | 153 (13.02) | 225 (19.35) | 39 (3.97) | 64 (12.70) |
FHx of CAD
| ||||
No | 1090 (92.77) | 1122 (96.47) | 921 (93.79) | 466 (92.46) |
Yes | 85 (7.23) | 41 (3.53) | 61 (6.21) | 38 (7.54) |
Smoke
| ||||
Never | 933 (79.40) | 866 (74.46) | 654 (66.60) | 357 (70.83) |
Occasion | 99 (8.43) | 63 (5.42) | 71 (7.23) | 37 (7.34) |
Often | 114 (9.70) | 196 (16.85) | 183 (18.64) | 78 (15.48) |
Quitting | 29 (2.47) | 38 (3.27) | 74 (7.54) | 32 (6.35) |
Drink
| ||||
Never | 771 (65.62) | 944 (81.17) | 781 (79.53) | 412 (81.75) |
Occasionally | 354 (30.13) | 133 (11.44) | 108 (11.00) | 50 (9.92) |
Often | 36 (3.06) | 52 (4.47) | 63 (6.42) | 22 (4.37) |
Quitting | 14 (1.19) | 34 (2.92) | 30 (3.05) | 20 (3.97) |
Staple food (liang/day)
| ||||
Never or < 3 | 626 (52.94) | 708 (60.88) | 291 (29.63) | 193 (38.29) |
3–6 | 489 (41.62) | 379 (32.59) | 567 (57.74) | 279 (55.36) |
≥ 6 | 64 (5.45) | 76 (6.53) | 124 (12.63) | 32 (6.35) |
Meat (times/week)
| ||||
Never or < 7 | 29 (2.47) | 152 (13.07) | 134 (13.65) | 71 (14.09) |
7–14 | 483 (41.11) | 486 (41.79) | 497 (50.61) | 255 (50.60) |
14 or more | 663 (56.43) | 525 (45.14) | 351 (35.74) | 178 (35.32) |
Vegetable (times/week)
| ||||
Never or < 7 | 24 (1.96) | 35 (2.75) | 88 (8.55) | 29 (5.16) |
7–14 | 434 (36.94) | 521 (44.80) | 499 (50.81) | 252 (50.00) |
14 | 717 (61.02) | 607 (52.19) | 395 (40.22) | 223 (44.25) |
Fruit (times/week)
| ||||
Never | 15 (1.28) | 221 (19.00) | 93 (9.47) | 64 (12.70) |
< 7 | 572 (48.68) | 724 (62.25) | 754 (76.78) | 367 (78.82) |
7–14 | 556 (47.32) | 203 (17.45) | 123 (12.53) | 64 (12.70) |
14 or more | 32 (2.72) | 15 (1.29) | 12 (1.22) | 9 (1.79) |
Sweet(times/week)
| ||||
Never | 278 (23.66) | 760 (65.35) | 364 (37.07) | 300 (59.52) |
< 3 | 715 (60.85) | 274 (23.56) | 522 (53.16) | 173 (34.33) |
3–7 | 162 (13.79) | 87 (7.48) | 78 (7.94) | 23 (4.56) |
7 or more | 20 (1.70) | 42 (3.61) | 18 (1.83) | 8 (1.59) |
Exercise
| ||||
No | 330 (28.09) | 614 (52.79) | 524 (53.36) | 280 (55.56) |
Yes | 845 (71.91) | 549 (47.21) | 458 (46.64) | 224 (44.44) |
Sleep(hours/day)
| ||||
< 5 or need medication | 40 (3.40) | 130 (11.18) | 199 (20.26) | 106 (21.03) |
5–7 | 594 (50.55) | 614 (52.79) | 435 (44.30) | 217 (43.06) |
7–9 | 523 (44.51) | 402 (34.57) | 270 (27.49) | 152 (30.16) |
≥ 9 | 18 (1.53) | 17 (1.46) | 78 (7.94) | 29 (5.75) |
BMI(kg/m)2 | 23.43 ± 3.40 | 23.66 ± 3.98 | 22.99 ± 3.21 | 23.60 ± 3.28 |
Central obesity
| ||||
No | 897 (76.09) | 719 (61.82) | 646 (65.78) | 287 (56.94) |
Yes | 281 (23.91) | 444 (38.18) | 336 (34.22) | 217 (43.06) |
SBP (mmHg)
| 122.70 ± 16.11 | 135.79 ± 21.85 | 139.34 ± 21.21 | 142.15 ± 22.04 |
DBP (mmHg)
| 74.05 ± 11.05 | 77.52 ± 12.06 | 77.99 ± 12.10 | 77.17 ± 12.06 |
Heart rate (times/min)
| 79.49 ± 12.15 | 81.44 ± 12.18 | 74.12 ± 12.44 | 6.55 ± 11.64 |
FBG (mmol/l)
| 4.87(4.56,5.22) | 7.80(5.64,1.40) | 5.03(4.57,5.70) | 7.61(5.47, .73) |
TG (mmol/l)
| 1.13(0.81, .72) | 1.47(1.00, .21) | 1.29(0.94, .81) | 1.48(1.04, .02) |
TC (mmol/l)
| 5.20 ± 1.10 | 5.16 ± 1.47 | 4.81 ± 1.31 | 4.63 ± 1.35 |
HDL-C (mmol/l)
| 1.37 ± 0.36 | 1.21 ± 0.47 | 1.21 ± 0.33 | 1.14 ± 0.31 |
LDL-C (mmol/l)
| 2.67 ± 1.36 | 3.14 ± 1.28 | 2.89 ± 1.12 | 2.68 ± 1.08 |
Preliminary screening of influencing factors of type 2 diabetes, coronary heart disease and their comorbidity
Variable | T2DM | CHD | Comorbidity | |||
---|---|---|---|---|---|---|
t/χ2
|
P
| t/χ2
|
P
| t/χ2
|
P
| |
Age
| -35.502 | < 0.001 | -47.784 | < 0.001 | -43.520 | < 0.001 |
Sex
| 12.411 | < 0.001 | 2.803 | 0.094 | 0.002 | 0.964 |
Area
| 648.232 | < 0.001 | 546.043 | < 0.001 | 377.617 | < 0.001 |
Education
| 1026.959 | < 0.001 | 1056.097 | < 0.001 | 694.446 | < 0.001 |
Marriage
| 203.301 | < 0.001 | 224.917 | < 0.001 | 114.925 | < 0.001 |
Occupation
| 901.096 | < 0.001 | 809.569 | < 0.001 | 545.586 | < 0.001 |
FHx of DM
| 17.253 | < 0.001 | 54.027 | < 0.001 | 0.033 | 0.857 |
FHx of CAD
| 15.767 | < 0.001 | 0.886 | 0.347 | 0.049 | 0.826 |
Smoke
| 33.334 | < 0.001 | 72.664 | < 0.001 | 28.791 | < 0.001 |
Drink
| 128.925 | < 0.001 | 127.989 | < 0.001 | 88.035 | < 0.001 |
Staple food
| 20.469 | < 0.001 | 128.673 | < 0.001 | 30.639 | < 0.001 |
Meat (times/week)
| 99.566 | < 0.001 | 147.752 | < 0.001 | 118.550 | < 0.001 |
Vegetable (times/week)
| 19.054 | < 0.001 | 118.017 | < 0.001 | 47.853 | < 0.001 |
Fruit (times/week)
| 367.913 | < 0.001 | 352.080 | < 0.001 | 250.290 | < 0.001 |
Sweet (times/week)
| 450.810 | < 0.001 | 54.304 | < 0.001 | 205.969 | < 0.001 |
Exercise
| 148.235 | < 0.001 | 142.887 | < 0.001 | 115.065 | < 0.001 |
Sleep
| 63.775 | < 0.001 | 233.162 | < 0.001 | 170.673 | < 0.001 |
BMI (kg/m)2
| -1.532 | < 0.126a
| 3.085 | 0.002a
| -0.963 | 0.336a
|
Central obesity
| 55.573 | < 0.001 | 27.794 | < 0.001 | 61.938 | < 0.001 |
SBP (mmHg)
| -16.477 | < 0.001a
| -20.191 | < 0.001a
| -17.864 | < 0.001a
|
DBP (mmHg)
| -7.250 | < 0.001a
| -7.845 | < 0.001a
| -4.989 | < 0.001a
|
Heart rate (times/min)
| -3.880 | < 0.001a
| 10.118 | < 0.001a
| 4.609 | < 0.001a
|
FBG (mmol/l)
| - | - | -5.257 | < 0.001b
| -20.689 | < 0.001b
|
TG (mmol/l)
| -10.037 | < 0.001b
| -5.262 | < 0.001b
| -8.471 | < 0.001b
|
TC (mmol/l)
| 0.876 | 0.381a
| 7.460 | < 0.001a
| 8.421 | < 0.001a
|
HDL-C (mmol/l)
| 9.421 | < 0.001a
| 11.019 | < 0.001a
| 13.512 | < 0.001a
|
LDL-C (mmol/l)
| -8.548 | < 0.001a
| 4.103 | < 0.001a
| -0.203 | 0.840a
|
Logistic regression analysis of type 2 diabetes, coronary heart disease and their comorbidities
Variable | Assign |
---|---|
Sex | Male = 1a, female = 2 |
Area | Rural = 1a, suburban = 2, urban = 3 |
Education | Illiteracy (low) = 1a, primary, middle, high school or technical secondary school (middle) = 2, college, bachelor, master's degree and above (high) = 3 |
Marriage | Married = 1a, unmarried, divorced, widowed = 2 |
Occupation | Agriculture and forestry = 1a, business service = 2, military, national party = 3, students = 4, others = 5 |
FHx of DM | No = 0a, and Yes = 1 |
FHx of CAD | No = 0a, and Yes = 1 |
Smoke | Never = 1a, occasionally (< 10 cigarettes/day) = 2, often (≥ 10 cigarettes/day) = 3, quitting (no smoking in the last 6 months) = 4 |
Drink | Never = 1a, occasionally (< 3 times/week) = 2, often (≥ 3 times/week) = 3, quitting (no alcohol in the last 6 months) = 4 |
Staple food | Never or < 3 liang/day = 1a, 3–6 liang /day = 2, ≥ 6 liang /day = 3 |
Meat | Never or < 7 times/week = 1a, 7–14 times/week = 2,14 times or more/week = 3 |
Vegetable | Never or < 7 times/week = 1a, 7–14 times/week = 2,14 times or more/week = 3 |
Fruit intake | Never = 1a, < 7 times/week = 2, 7–14 times/week = 3,14 times or more/week = 4 |
Sweet | Never = 1a, < 3 times/week = 2, 3–7 times/week = 3, 7 times or more/week = 4 |
Exercise | No = 0a, and Yes = 1 |
Sleep | < 5 h/day or need medicine to help sleep = 1a, 5–7 h/day = 2, 7–9 h/day = 3, ≥ 9 h/day = 4 |
Variable |
Beta
|
\(\boldsymbol{S}_{\boldsymbol{\bar{x}}}\)
| Wald χ2
|
P
|
OR(95%CI)
|
---|---|---|---|---|---|
Age
| 0.077 | 0.007 | 115.551 | < 0.001 | 1.080(1.065 ~ 1.095) |
Area
| |||||
Rural | 124.932 | < 0.001 | |||
Suburban | -0.587 | 0.360 | 2.668 | 0.102 | 0.556(0.275 ~ 1.125) |
Urban | -2.661 | 0.283 | 88.421 | < 0.001 | 0.070(0.040 ~ 0.122) |
Education
| |||||
Low | 51.399 | < 0.001 | |||
Middle | 0.070 | 0.511 | 0.019 | 0.892 | 1.072 0.393 ~ 2.922) |
High | -1.290 | 0.537 | 5.775 | 0.016 | 0.275 0.096 ~ 0.788) |
Occupation
| |||||
Agriculture and forestry | 76.512 | < 0.001 | |||
Business services | 1.243 | 0.331 | 14.082 | < 0.001 | 3.467(1.811 ~ 6.638) |
Military, national party | 1.037 | 0.273 | 14.408 | < 0.001 | 0.354(0.207 ~ 0.606) |
Students | 1.472 | 0.758 | 3.766 | 0.052 | 0.230(0.052 ~ 1.015) |
Others | 0.087 | 0.255 | 0.116 | 0.734 | 1.091 0.661 ~ 1.799) |
FHx of DM
| 1.617 | 0.226 | 51.136 | < 0.001 | 5.040 (3.235 ~ 7.852) |
Smoke
| |||||
Never | 14.581 | 0.002 | |||
Occasionally | 0.396 | 0.317 | 1.562 | 0.211 | 0.673 (0.361 ~ 1.253) |
Often | 0.667 | 0.235 | 8.092 | 0.004 | 1.949 (1.231 ~ 3.087) |
Quitting | 0.669 | 0.445 | 2.258 | 0.133 | 0.512 (0.214 ~ 1.226) |
Drink
| |||||
Never | 20.991 | < 0.001 | |||
Occasionally | -0.890 | 0.211 | 17.762 | < 0.001 | 0.411 (0.271 ~ 0.621) |
Often | -0.449 | 0.386 | 1.352 | 0.245 | 0.638 (0.300 ~ 1.360) |
Quitting | 0.562 | 0.501 | 1.260 | 0.262 | 1.754 (0.658 ~ 4.679) |
Staple food (liang/day)
| |||||
Never or < 3 | 28.219 | < 0.001 | |||
3–6 | 0.833 | 0.177 | 22.286 | < 0.001 | 0.435 (0.307 ~ 0.614) |
≥ 6 | 0.344 | 0.324 | 1.127 | 0.288 | 1.411 (0.747 ~ 2.666) |
Meat (times/week)
| |||||
Never or < 7 | 14.344 | 0.001 | |||
7–14 | 1.112 | 0.381 | 8.504 | 0.004 | 0.329 (0.156 ~ 0.694) |
14 or more | 1.393 | 0.379 | 13.517 | < 0.001 | 0.248 (0.118 ~ 0.522) |
Fruit (times/week)
| |||||
Never | 28.481 | < 0.001 | |||
< 7 | 1.551 | 0.403 | 14.825 | < 0.001 | 0.212 (0.096 ~ 0.467) |
7–14 | 2.100 | 0.417 | 25.295 | < 0.001 | 0.122 (0.054 ~ 0.278) |
14 or more | 1.478 | 0.637 | 5.384 | 0.020 | 0.228 (0.065 ~ 0.795) |
Sweet (times/week)
| |||||
Never | 40.793 | < 0.001 | |||
< 3 | 1.058 | 0.180 | 34.591 | < 0.001 | 0.347 (0.244 ~ 0.494) |
3–7 | 0.535 | 0.269 | 3.951 | 0.047 | 0.586 (0.346 ~ 0.993) |
7 or more | 0.516 | 0.455 | 1.287 | 0.257 | 1.675 (0.687 ~ 4.082) |
Exercise
| 0.920 | 0.166 | 30.823 | < 0.001 | 0.399 (0.288 ~ 0.552) |
Heart rate (times/min)
| 0.027 | 0.007 | 15.924 | < 0.001 | 1.027 (1.014 ~ 1.041) |
TG (mmol/l)
| 0.085 | 0.041 | 4.272 | 0.039 | 1.089 (1.004 ~ 1.180) |
HDL-C (mmol/l)
| 0.975 | 0.170 | 32.816 | < 0.001 | 0.377 (0.270 ~ 0.527) |
LDL-C (mmol/l)
| 0.417 | 0.062 | 44.921 | < 0.001 | 1.343 (1.340 ~ 1.714) |
Variable | Beta |
\(\boldsymbol{S}_{\boldsymbol{\bar{x}}}\)
| Wald χ2 | P | OR (95% CI ) |
---|---|---|---|---|---|
Age | 0.087 | 0.008 | 112.342 | < 0.001 | 1.091(1.074 ~ 1.109) |
Area | |||||
Rural | 40.217 | < 0.001 | |||
Suburban | 1.486 | 0.427 | 12.110 | 0.001 | 0.226(0.098 ~ 0.523) |
Urban | 2.067 | 0.329 | 39.407 | < 0.001 | 0.127(0.066 ~ 0.241) |
Education | |||||
Low | 30.364 | < 0.001 | |||
Middle | 0.373 | 0.671 | 0.309 | 0.578 | 0.689(0.185 ~ 2.564) |
High | 1.553 | 0.695 | 4.993 | 0.025 | 0.212(0.054 ~ 0.826) |
Marriage | 1.299 | 0.428 | 9.208 | 0.002 | 0.273(0.118 ~ 0.631) |
Occupation | |||||
Agriculture and forestry | 24.161 | < 0.001 | |||
Business services | 0.284 | 0.409 | 0.482 | 0.488 | 1.328 (0.596 ~ 2.957) |
Military, national party | 0.957 | 0.298 | 10.345 | 0.001 | 0.384 (0.214 ~ 0.688) |
Students | 2.146 | 2.001 | 1.150 | 0.283 | 0.117 (0.002 ~ 5.902) |
Others | 0.006 | 0.293 | 0.000 | 0.985 | 0.994 (0.560 ~ 1.764) |
Smoke | |||||
Never | 20.055 | < 0.001 | |||
Occasionally | 0.387 | 0.330 | 1.373 | 0.241 | 1.472 (0.771 ~ 2.812) |
Often | 1.174 | 0.264 | 19.828 | < 0.001 | 3.235 (1.929 ~ 5.423) |
Quitting | 0.144 | 0.436 | 0.110 | 0.740 | 1.155 (0.492 ~ 2.713) |
Drink | |||||
Never | 7.898 | 0.048 | |||
Occasionally | 0.656 | 0.238 | 7.580 | 0.006 | 0.519 (0.326 ~ 0.828) |
Often | 0.013 | 0.373 | 0.001 | 0.972 | 0.987 (0.475 ~ 2.052) |
Quitting | 0.288 | 0.679 | 0.180 | 0.671 | 0.750 (0.198 ~ 2.835) |
Staple food (liang/day) | |||||
Never or < 3 | 13.188 | 0.001 | |||
3–6 | 0.420 | 0.206 | 4.135 | 0.042 | 1.521 (1.015 ~ 2.280) |
≥ 6 | 1.198 | 0.335 | 12.797 | < 0.001 | 3.314 (1.719 ~ 6.388) |
Meat (times/week) | |||||
Never or < 7 | 6.668 | 0.036 | |||
7–14 | 1.116 | 0.433 | 6.649 | 0.010 | 0.328 (0.140 ~ 0.765) |
14 or more | 1.033 | 0.436 | 5.608 | 0.018 | 0.356 (0.151 ~ 0.837) |
Fruit (times/week) | |||||
Never | 25.911 | < 0.001 | |||
< 7 | 1.461 | 0.559 | 6.838 | 0.009 | 0.232 (0.078 ~ 0.694) |
7–14 | 2.339 | 0.580 | 16.262 | < 0.001 | 0.096 (0.031 ~ 0.301) |
14 or more | 1.845 | 0.780 | 5.602 | 0.018 | 0.158 (0.034 ~ 0.728) |
Exercise | 0.518 | 0.192 | 7.263 | 0.007 | 0.596 (0.409 ~ 0.868) |
Sleep | |||||
< 5 or need medication | 13.365 | 0.004 | |||
5–7 | 0.730 | 0.316 | 5.316 | 0.021 | 0.482 (0.259 ~ 0.896) |
7–9 | 0.666 | 0.327 | 4.137 | 0.042 | 0.514 (0.271 ~ 0.976) |
≥ 9 | 0.934 | 0.626 | 2.230 | 0.135 | 2.546 (0.747 ~ 8.679) |
SBP (mmHg) | 0.019 | 0.005 | 14.343 | < 0.001 | 1.020 (1.009 ~ 1.030) |
Heart rate (times/min) | 0.023 | 0.008 | 9.076 | 0.003 | 0.978 (0.963 ~ 0.992) |
TG (mmol/l) | 0.131 | 0.062 | 4.450 | 0.035 | 1.140 (1.009 ~ 1.287) |
TC (mmol/l) | 1.271 | 0.131 | 94.262 | < 0.001 | 0.280 (0.217 ~ 0.363) |
LDL-C (mmol/l) | 1.162 | 0.125 | 86.172 | < 0.001 | 3.197 (2.502 ~ 4.087) |
Variable |
Beta
|
\(\boldsymbol{S}_{\boldsymbol{\bar{x}}}\)
| Wald χ2
|
P
|
OR(95%CI)
|
---|---|---|---|---|---|
Age
| 0.100 | 0.010 | 98.677 | < 0.001 | 1.106 (1.084 ~ 1.128) |
Area
| |||||
Rural | 50.027 | < 0.001 | |||
Suburban | 0.570 | 0.471 | 1.462 | 0.227 | 0.565(0.22 ~ 1.425) |
Urban | 2.207 | 0.370 | 35.589 | < 0.001 | 0.110 (0.053 ~ 0.227) |
Education
| |||||
Low | 34.771 | < 0.001 | |||
Middle | 0.158 | 0.662 | 0.057 | 0.812 | 0.854 (0.233 ~ 3.127) |
High | 1.716 | 0.692 | 6.149 | 0.013 | 0.180 (0.046 ~ 0.698) |
Fruit (times/week)
| |||||
Never | 27.138 | < 0.001 | |||
< 7 | 1.423 | 0.610 | 5.446 | 0.020 | 0.241 (0.073 ~ 0.796) |
7–14 | 2.544 | 0.639 | 15.840 | < 0.001 | 0.079 (0.022 ~ 0.275) |
14 or more | 0.977 | 0.888 | 1.211 | 0.271 | 0.376 (0.066 ~ 2.144) |
Sweet (times/week)
| |||||
Never | 9.463 | 0.024 | |||
< 3 | 0.704 | 0.231 | 9.260 | 0.002 | 0.495(0.314 ~ 0.778) |
3–7 | 0.498 | 0.406 | 1.498 | 0.221 | 0.608 (0.274 ~ 1.349) |
7 or more | 0.209 | 0.672 | 0.096 | 0.756 | 0.812 (0.217 ~ 3.032) |
Exercise
| 0.680 | 0.228 | 8.908 | 0.003 | 0.507 (0.324 ~ 0.792) |
SBP (mmHg)
| 0.026 | 0.008 | 11.120 | 0.001 | 1.026 (1.011 ~ 1.042) |
DBP (mmHg)
| -0.028 | 0.013 | 4.837 | 0.028 | 0.972 (0.948 ~ 0.997) |
FBG (mmol/l)
| 0.403 | 0.059 | 46.775 | < 0.001 | 1.496 (1.333 ~ 1.679) |
TC (mmol/l)
| 0.388 | 0.085 | 20.739 | < 0.001 | 0.678 (0.574 ~ 0.802) |
HDL-C (mmol/l)
| 1.895 | 0.363 | 27.194 | < 0.001 | 0.150 (0.074 ~ 0.307) |
BN learning
Structure learning
Variable | Assign |
---|---|
Age | 18 ~ 44 = 1, 45 ~ 59 = 2,60 ~ 3 |
BMI (kg/m)2
| < 18.49 = 1,18.5 ~ 23.99 = 2,24.0 ~ 27.99 = 3,28.0 ~ = 4 |
SBP (mmHg) | Normal = 0 (< 140), abnormal = 1 (≥ 140) |
DBP (mmHg) | Normal = 0 (< 90), abnormal = 1 (≥ 90) |
Heart rate (times/min) | Too slow = 1 (< 60), normal = 2 (60 ~ 100), too fast = 3 (> 100) |
FBG (mmol/L) | Normal = 0 (< 7.0), abnormal = 1 (≥ 7.0) |
TG (mmol/L) | Normal = 0 (< 2.3), abnormal = 1 (≥ 2.3) |
TC (mmol/L) | Normal = 0 (< 6.2), abnormal = 1 (≥ 6.2) |
HDL-C (mmol/L) | Normal = 0 (< 2.3), abnormal = 1 (≥ 2.3) |
LDL-C (mmol/L) | Normal = 0 (≥ 1.0), abnormal = 1 (< 1.0) |
Parameter learning
Age | Education | FHx | T2DM |
---|---|---|---|
18 to 44 | Low | No | 0.500 |
45 ~ 59 | Low | No | 0.833 |
60 ~ | Low | No | 0.935 |
18 to 44 | Middle | No | 0.404 |
45 ~ 59 | Middle | No | 0.737 |
60 ~ | Middle | No | 0.840 |
18 to 44 | High | No | 0.032 |
45 ~ 59 | High | No | 0.198 |
60 ~ | High | No | 0.307 |
18 to 44 | Low | Yes | 0.000 |
45 ~ 59 | Low | Yes | 1.000 |
60 ~ | Low | Yes | 1.000 |
18 to 44 | Middle | Yes | 0.826 |
45 ~ 59 | Middle | Yes | 0.915 |
60 ~ | Middle | Yes | 0.981 |
18 to 44 | High | Yes | 0.094 |
45 ~ 59 | High | Yes | 0.500 |
60 ~ | High | Yes | 0.857 |
Age | Smoke | SBP | CAD |
---|---|---|---|
18 to 44 | Never | normal | 0.018 |
45 ~ 59 | Never | normal | 0.383 |
60 ~ | Never | normal | 0.774 |
18 to 44 | Occasionally | normal | 0.021 |
45 ~ 59 | Occasionally | normal | 0.400 |
60 ~ | Occasionally | normal | 0.619 |
18 to 44 | Often | normal | 0.235 |
45 ~ 59 | Often | normal | 0.556 |
60 ~ | Often | normal | 0.902 |
18 to 44 | Quitting | normal | 0.000 |
45 ~ 59 | Quitting | normal | 0.666 |
60 ~ | Quitting | normal | 0.824 |
18 to 44 | Never | abnormal | 0.040 |
45 ~ 59 | Never | abnormal | 0.482 |
60 ~ | Never | abnormal | 0.863 |
18 to 44 | Occasionally | abnormal | 0.000 |
45 ~ 59 | Occasionally | abnormal | 0.875 |
60 ~ | Occasionally | abnormal | 0.958 |
18 to 44 | Often | abnormal | 0.333 |
45 ~ 59 | Often | abnormal | 0.778 |
60 ~ | Often | abnormal | 0.933 |
18 to 44 | Quitting | abnormal | 0.000 |
45 ~ 59 | Quitting | abnormal | 0.750 |
60 ~ | Quitting | abnormal | 0.826 |
Age | Exercise | SBP | FBG | Comorbidity |
---|---|---|---|---|
18 to 44 | No | normal | normal | 0.000 |
45 ~ 59 | No | normal | normal | 0.326 |
60 ~ | No | normal | normal | 0.712 |
18 to 44 | Yes | normal | normal | 0.000 |
45 ~ 59 | Yes | normal | normal | 0.098 |
60 ~ | Yes | normal | normal | 0.436 |
18 to 44 | No | abnormal | normal | 0.000 |
45 ~ 59 | No | abnormal | normal | 0.368 |
60 ~ | No | abnormal | normal | 0.843 |
18 to 44 | Yes | abnormal | normal | 0.000 |
45 ~ 59 | Yes | abnormal | normal | 0.292 |
60 ~ | Yes | abnormal | normal | 0.543 |
18 to 44 | No | normal | abnormal | 0.667 |
45 ~ 59 | No | normal | abnormal | 0.722 |
60 ~ | No | normal | abnormal | 0.977 |
18 to 44 | Yes | normal | abnormal | 0.000 |
45 ~ 59 | Yes | normal | abnormal | 0.667 |
60 ~ | Yes | normal | abnormal | 0.864 |
18 to 44 | No | abnormal | abnormal | 0.000 |
45 ~ 59 | No | abnormal | abnormal | 0.909 |
60 ~ | No | abnormal | abnormal | 0.964 |
18 to 44 | Yes | abnormal | abnormal | 0.250 |
45 ~ 59 | Yes | abnormal | abnormal | 0.769 |
60 ~ | Yes | abnormal | abnormal | 0.900 |
Network authentication
T2DM | CAD | Comorbidity | |||||
---|---|---|---|---|---|---|---|
True value |
( +)
|
(-)
|
( +)
|
(-)
|
( +)
|
(-)
| |
Predicted value |
( +)
| 313 | 60 | 240 | 47 | 122 | 29 |
(-)
| 50 | 279 | 47 | 307 | 33 | 317 |
Network reasoning
Sensitivity analysis
T2DM | CAD | Comorbidity | |||
---|---|---|---|---|---|
Variable | Variance reduction(%) | Variable | Variance reduction(%) | Variable | Variance reduction(%) |
education | 10.70 | age | 11.70 | age | 8.96 |
age | 8.72 | education | 4.11 | FBG | 5.19 |
area | 6.01 | occupation | 4.11 | education | 3.82 |
occupation | 5.72 | fruit | 3.97 | fruit | 3.06 |
sweet | 4.74 | SBP | 3.50 | SBP | 2.70 |
fruit | 3.90 | sleep | 2.65 | sweet | 2.44 |
sport | 1.58 | Marriage | 2.04 | HDL-C | 1.03 |
TG | 0.39 | sport | 1.65 | sport | 0.27 |
drink | 0.35 | meat | 1.58 | DBP | 0.23 |
HDL-C | 0.25 | HR | 0.67 | area | 0.01 |
meat | 0.22 | drink | 0.56 | TC | 0.00 |
LDL-C | 0.15 | staple food | 0.27 | ||
history | 0.14 | smoke | 0.26 | ||
staple food | 0.11 | TG | 0.02 | ||
HR | 0.04 | area | 0.01 | ||
smoke | 0.02 | TC | 0.00 | ||
LDL-C | 0.00 |