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Journal of Interventional Cardiac Electrophysiology

Erschienen in:

16.03.2023 | REVIEW

Cardiac arrhythmias in viral infections

verfasst von: Paul Y. Lee, Hasan Garan, Elaine Y. Wan, Brian E. Scully, Angelo Biviano, Hirad Yarmohammadi

Erschienen in: Journal of Interventional Cardiac Electrophysiology | Ausgabe 8/2023

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Abstract

Background

The current COVID-19 pandemic has led to many studies examining its arrhythmogenic effects. However, there are many other viruses that are capable of inducing arrhythmias that have not received as much attention. The objective of this study was to review common viruses and identify studies highlighting their arrhythmogenic effects.

Methods and results

In this review, we examined 15 viruses and the literature regarding their arrhythmogenic effects. The common mechanisms of action appear to be direct invasion of myocytes leading to immune mediated damage, infection of vascular endothelium, and alteration of cardiac ion channels.

Conclusions

This review highlights the growing evidence that supports the involvement of other viral infections in the development of arrhythmia. Physicians should be aware of these potentially life-threatening effects when caring for patients with these viruses, some of which are very common. Additional studies are required to better understand the complex mechanism and risk factors of cardiac arrhythmias in patients suffered from viral infections to determine whether the processes can be reversed or even prevented.

Babapoor-Farrokhran S, Rasekhi RT, Gill D, Babapoor S, Amanullah A. Arrhythmia in COVID-19. SN Compr Clin Med. 2020;2(9):1430–5. https://doi.org/10.1007/s42399-020-00454-2. ([published Online First: 20200814]).CrossRefPubMedPubMedCentral

Schaefer TJ, Panda PK, Wolford RW. Dengue fever. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK430732/

Linares EM, Pannuti CS, Kubota LT, Thalhammer S. Immunospot assay based on fluorescent nanoparticles for dengue fever detection. Biosens Bioelectron. 2013;41:180–5. https://doi.org/10.1016/j.bios.2012.08.005. ([published Online First: 20120816]).CrossRefPubMed

Parchani A, Krishnan Vs G, Kumar VKS. Electrocardiographic changes in dengue fever: a review of literature. Int J Gen Med. 2021;14:5607–14. https://doi.org/10.2147/IJGM.S328755. ([published Online First: 20210914]).CrossRefPubMedPubMedCentral

Poornima H, John J. Cardiac manifestations in dengue patients in a rural tertiary care centre in Coastal Kerala. Int J Innov Res Med Sci. 2019;4(04):302 to 03. https://doi.org/10.23958/ijirms/vol04-i04/628.CrossRef

Shah C, Vijayaraghavan G, Kartha CC. Spectrum of cardiac involvement in patients with dengue fever. Int J Cardiol. 2021;324:180–5. https://doi.org/10.1016/j.ijcard.2020.09.034. ([published Online First: 20200913]).CrossRefPubMed

Pialoux G, Gauzere BA, Jaureguiberry S, Strobel M. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis. 2007;7(5):319–27. https://doi.org/10.1016/S1473-3099(07)70107-X.CrossRefPubMed

Ojeda Rodriguez JA, Haftel A, Walker IJ. Chikungunya fever. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK534224/

Obeyesekere I, Hermon Y. Arbovirus heart disease: myocarditis and cardiomyopathy following dengue and chikungunya fever–a follow-up study. Am Heart J. 1973;85(2):186–94. https://doi.org/10.1016/0002-8703(73)90459-6.CrossRefPubMed

10.

Carta KAG, Mendoza-Britto IJ, Finizola V, et al. Abstract 13292: Bradycardia as a manifestation of chikungunya myocarditis. A new threat to America. Circulation. 2016;134(suppl_1):A13292–A92. https://doi.org/10.1161/circ.134.suppl_1.13292.CrossRef

11.

Villamil-Gómez WE, Ramirez-Vallejo E, Cardona-Ospina JA, Silvera LA, Rodríguez-Morales AJ. Electrocardiographic alterations in patients with chikungunya fever from Sucre, Colombia: a 42-case series. Travel Med Infect Dis. 2016;14(5):510–2. https://doi.org/10.1016/j.tmaid.2016.06.004.CrossRefPubMed

12.

Wolford RW, Schaefer TJ. Zika virus. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK430981/

13.

Zambrana JV, Bustos Carrillo F, Burger-Calderon R, et al. Seroprevalence, risk factor, and spatial analyses of Zika virus infection after the 2016 epidemic in Managua, Nicaragua. Proc Natl Acad Sci U S A. 2018;115(37):9294–9. https://doi.org/10.1073/pnas.1804672115. ([published Online First: 20180827]).CrossRefPubMedPubMedCentral

14.

Hills SL, Fischer M, Petersen LR. Epidemiology of Zika virus infection. J Infect Dis. 2017;216(suppl_10):868–74. https://doi.org/10.1093/infdis/jix434.CrossRef

15.

Scatularo CE, Ballesteros OA, Saldarriaga C, et al. Zika & heart: a systematic review. Trends Cardiovasc Med. 2022;32(1):52–8. https://doi.org/10.1016/j.tcm.2020.11.003. ([published Online First: 20201118]).CrossRefPubMed

16.

Bai C, Li S, Song S, et al. Zika virus induces myocardial immune response and myocarditis in mice. J Mol Cell Cardiol. 2020;148:103–5. https://doi.org/10.1016/j.yjmcc.2020.08.014CrossRefPubMedPubMedCentral

17.

Mendoza I, Gonzalez K, Morr I, et al. Abstract 13257: A rash from the heart. Zika myocarditis manifesting with coexisting acute atrial and ventricular arrhythmias and itchy rash. Circulation. 2018;138(Suppl_1):A13257–A57. https://doi.org/10.1161/circ.138.suppl_1.13257.CrossRef

18.

Villamil-Gómez WE, Ramirez-Vallejo E, Rodriguez-Morales AJ. Cardiac compromise in Zika virus infection. Mayo Clin Proc. 2018;93(3):393–4. https://doi.org/10.1016/j.mayocp.2017.12.006.CrossRefPubMed

19.

Abdalla LF, Santos JHA, Barreto RTJ, et al. Atrial fibrillation in a patient with Zika virus infection. Virol J. 2018;15(1):23. https://doi.org/10.1186/s12985-018-0938-2[publishedOnlineFirst:20180125].CrossRefPubMedPubMedCentral

20.

Cascella M, Rajnik M, Aleem A, Dulebohn SC, Di Napoli R. Features, evaluation, and treatment of coronavirus (COVID-19). StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK554776/

21.

Xu H, Zhong L, Deng J, et al. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Int J Oral Sci. 2020;12(1):8. https://doi.org/10.1038/s41368-020-0074-x. ([published Online First: 20200224]).CrossRefPubMedPubMedCentral

22.

Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan. China Lancet. 2020;395(10223):497–506. https://doi.org/10.1016/S0140-6736(20)30183-5. ([published Online First: 20200124]).CrossRefPubMed

23.

Rosenblatt AG, Ayers CR, Rao A, et al. New-onset atrial fibrillation in patients hospitalized with COVID-19: results from the American Heart Association COVID-19 Cardiovascular Registry. Circ Arrhythm Electrophysiol. 2022;15(5):e010666. https://doi.org/10.1161/CIRCEP.121.010666. ([published Online First: 20220427]).CrossRefPubMed

24.

Mountantonakis SE, Saleh M, Fishbein J, et al. Atrial fibrillation is an independent predictor for in-hospital mortality in patients admitted with SARS-CoV-2 infection. Heart Rhythm. 2021;18(4):501–7. https://doi.org/10.1016/j.hrthm.2021.01.018. ([published Online First: 20210122]).CrossRefPubMedPubMedCentral

25.

Li Z, Shao W, Zhang J, et al. Prevalence of atrial fibrillation and associated mortality among hospitalized patients with COVID-19: a systematic review and meta-analysis. Front Cardiovasc Med. 2021;8:720129. https://doi.org/10.3389/fcvm.2021.720129. ([published Online First: 20211013]).CrossRefPubMedPubMedCentral

26.

Peltzer B, Manocha KK, Ying X, et al. Arrhythmic complications of patients hospitalized with COVID-19: incidence, risk factors, and outcomes. Circ Arrhythm Electrophysiol. 2020;13(10):e009121. https://doi.org/10.1161/CIRCEP.120.009121. ([published Online First: 20200915]).CrossRefPubMedPubMedCentral

27.

Coromilas EJ, Kochav S, Goldenthal I, et al. Worldwide survey of COVID-19-associated arrhythmias. Circ Arrhythm Electrophysiol. 2021;14(3):e009458. https://doi.org/10.1161/CIRCEP.120.009458. ([published Online First: 20210207]).CrossRefPubMedPubMedCentral

28.

Bhatla A, Mayer MM, Adusumalli S, et al. COVID-19 and cardiac arrhythmias. Heart Rhythm. 2020;17(9):1439–44. https://doi.org/10.1016/j.hrthm.2020.06.016. ([published Online First: 20200622]).CrossRefPubMedPubMedCentral

29.

Cho JH, Namazi A, Shelton R, et al. Cardiac arrhythmias in hospitalized patients with COVID-19: a prospective observational study in the western United States. PLoS One. 2020;15(12):e0244533. https://doi.org/10.1371/journal.pone.0244533. ([published Online First: 20201228]).CrossRefPubMedPubMedCentral

30.

Tariq N, Kyriakopoulos C. Group B coxsackie virus. StatPearls. Treasure Island (FL), 2022. https://pubmed.ncbi.nlm.nih.gov/32809618/

31.

Esfandiarei M, McManus BM. Molecular biology and pathogenesis of viral myocarditis. Annu Rev Pathol. 2008;3:127–55. https://doi.org/10.1146/annurev.pathmechdis.3.121806.151534.CrossRefPubMed

32.

Knowlton KU. CVB infection and mechanisms of viral cardiomyopathy. Curr Top Microbiol Immunol. 2008;323:315–35. https://doi.org/10.1007/978-3-540-75546-3_15.CrossRefPubMed

33.

Oldfors A, Eriksson BO, Kyllerman M, Martinsson T, Wahlstrom J. Dilated cardiomyopathy and the dystrophin gene: an illustrated review. Br Heart J. 1994;72(4):344–8. https://doi.org/10.1136/hrt.72.4.344.CrossRefPubMedPubMedCentral

34.

Shi Y, Chen C, Lisewski U, et al. Cardiac deletion of the coxsackievirus-adenovirus receptor abolishes coxsackievirus B3 infection and prevents myocarditis in vivo. J Am Coll Cardiol. 2009;53(14):1219–26. https://doi.org/10.1016/j.jacc.2008.10.064.CrossRefPubMed

35.

Terasaki F, Kitaura Y, Hayashi T, Nakayama Y, Deguchi H, Kawamura K. Arrhythmias in coxsackie B3 virus myocarditis. Continuous electrocardiography in conscious mice and histopathology of the heart with special reference to the conduction system. Heart Vessels Suppl. 1990;5:45–50.PubMed

36.

Steinke K, Sachse F, Ettischer N, et al. Coxsackievirus B3 modulates cardiac ion channels. FASEB J. 2013;27(10):4108–21. https://doi.org/10.1096/fj.13-230193. ([published Online First: 20130627]).CrossRefPubMed

37.

Cunningham R, Silbergleit R. Viral myocarditis presenting with seizure and electrocardiographic findings of acute myocardial infarction in a 14-month-old child. Ann Emerg Med. 2000;35(6):618–22.CrossRefPubMed

38.

Tai YT, Lau CP, Fong PC, Li JP, Lee KL. Incessant automatic ventricular tachycardia complicating acute coxsackie B myocarditis. Cardiology. 1992;80(5–6):339–44. https://doi.org/10.1159/000175023.CrossRefPubMed

39.

Sato Y, Osaku A, Koyama S, et al. Complete atrioventricular block associated with regional myocardial scarring in a patient with coxsackie B2 myocarditis. Jpn Heart J. 1989;30(6):935–41. https://doi.org/10.1536/ihj.30.935.CrossRefPubMed

40.

Sareli P, Schamroth CL, Passias J, Schamroth L. Torsade de pointes due to coxsackie B3 myocarditis. Clin Cardiol. 1987;10(5):361–2. https://doi.org/10.1002/clc.4960100514.CrossRefPubMed

41.

Badorff C, Zeiher AM, Hohnloser SH. Torsade de pointes tachycardia as a rare manifestation of acute enteroviral myocarditis. Heart. 2001;86(5):489–90. https://doi.org/10.1136/heart.86.5.489.CrossRefPubMedPubMedCentral

42.

Usman N, Suarez M. Adenoviruses. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK559072/

43.

Lynch JP 3rd, Kajon AE. Adenovirus: epidemiology, global spread of novel serotypes, and advances in treatment and prevention. Semin Respir Crit Care Med. 2016;37(4):586–602. https://doi.org/10.1055/s-0036-1584923. ([published Online First: 20160803]).CrossRefPubMedPubMedCentral

44.

Ghebremedhin B. Human adenovirus: viral pathogen with increasing importance. Eur J Microbiol Immunol (Bp). 2014;4(1):26–33. https://doi.org/10.1556/EuJMI.4.2014.1.2. ([published Online First: 20140314]).CrossRefPubMed

45.

Bowles NE, Ni J, Kearney DL, et al. Detection of viruses in myocardial tissues by polymerase chain reaction. Evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol. 2003;42(3):466–72. https://doi.org/10.1016/s0735-1097(03)00648-x.CrossRefPubMed

46.

Bergelson JM, Cunningham JA, Droguett G, et al. Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5. Science. 1997;275(5304):1320–3. https://doi.org/10.1126/science.275.5304.1320.CrossRefPubMed

47.

Padget RL, King DR, North MD, et al. Abstract MP114: Cardiotropic adenovirus increases arrhythmia susceptibility during acute infection. Circ Res. 2020;127(Suppl_1):AMP114–AMP14. https://doi.org/10.1161/res.127.suppl_1.MP114.CrossRef

48.

Savon C, Acosta B, Valdes O, et al. A myocarditis outbreak with fatal cases associated with adenovirus subgenera C among children from Havana City in 2005. J Clin Virol. 2008;43(2):152–7. https://doi.org/10.1016/j.jcv.2008.05.012. ([published Online First: 20080725]).CrossRefPubMed

49.

Valdés O, Acosta B, Piñón A, et al. First report on fatal myocarditis associated with adenovirus infection in Cuba. J Med Virol. 2008;80(10):1756–61. https://doi.org/10.1002/jmv.21274.CrossRefPubMedPubMedCentral

50.

Treacy A, Carr MJ, Dunford L, et al. First report of sudden death due to myocarditis caused by adenovirus serotype 3. J Clin Microbiol. 2010;48(2):642–5. https://doi.org/10.1128/JCM.00815-09. ([published Online First: 20091125]).CrossRefPubMed

51.

Splaingard ML, Frazier OH, Jefferson LS, Stein F, Harrison GM. Extracorporeal membrane oxygenation: its role in the survival of a child with adenoviral pneumonia and myocarditis. South Med J. 1983;76(9):1171–3.CrossRefPubMed

52.

Henson D, Mufson MA. Myocarditis and pneumonitis with type 21 adenovirus infection. Association with fatal myocarditis and pneumonitis. Am J Dis Child. 1971;121(4):334–6. https://doi.org/10.1001/archpedi.1971.02100150108015.CrossRefPubMed

53.

Camejo Leonor M, Mendez MD. Rubella. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK559040/

54.

Rubella surveillance no. 1, June 1969. In: National Communicable Disease C, ed. Atlanta, GA, 1969. https://www.cdc.gov/vaccines/pubs/surv-manual/chpt14-rubella.html

55.

Oster ME, Riehle-Colarusso T, Correa A. An update on cardiovascular malformations in congenital rubella syndrome. Birth Defects Res A Clin Mol Teratol. 2010;88(1):1–8. https://doi.org/10.1002/bdra.20621.CrossRefPubMed

56.

Thanopoulos BD, Rokas S, Frimas CA, Mantagos SP, Beratis NG. Cardiac involvement in postnatal rubella. Acta Paediatr Scand. 1989;78(1):141–4. https://doi.org/10.1111/j.1651-2227.1989.tb10905.x.CrossRefPubMed

57.

Logue R, Hanson JF. Complete heart block in German measles. Am Heart J. 1945;30:205.CrossRef

58.

Goldfinger D, Schreiber W, Wosika PH. Permanent heart block following German measles. Am J Med. 1947;2(3):320–3. https://doi.org/10.1016/0002-9343(47)90237-4.CrossRefPubMed

59.

Uemura A, Morimoto S, Hiramitsu S, et al. A case of brain stem encephalitis complicated with bifascicular block caused by rubella virus. Kokyu To Junkan. 1992;40(5):499–503.PubMed

60.

Kasturi N, Matalia J, Tejwani S, Shetty BK. Wolff-Parkinson-White syndrome in congenital rubella syndrome. Indian J Pediatr. 2014;81(12):1392–3. https://doi.org/10.1007/s12098-014-1349-z. ([published Online First: 20140225]).CrossRefPubMed

61.

Fukushige J, Kuroiwa T, Ueda K, Miyazaki C, Takagi S. Supraventricular tachycardia in acquired rubella infection: a case report. Acta Paediatr Jpn. 1990;32(1):94–7. https://doi.org/10.1111/j.1442-200x.1990.tb00790.x.CrossRefPubMed

62.

Justiz Vaillant AA, Gulick PG. HIV disease current practice. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK534860/

63.

HIV/AIDS JUNPo. Fact sheet. Global HIV & AIDS statistics 2022. https://www.unaids.org/en/resources/fact-sheet

64.

Gupta MK, Kaminski R, Mullen B, et al. HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy. Sci Rep. 2017;7(1):8572. https://doi.org/10.1038/s41598-017-08736-x. ([published Online First: 20170817]).CrossRefPubMedPubMedCentral

65.

Currier JS, Taylor A, Boyd F, et al. Coronary heart disease in HIV-infected individuals. J Acquir Immune Defic Syndr. 2003;33(4):506–12. https://doi.org/10.1097/00126334-200308010-00012.CrossRefPubMed

66.

Tseng ZH, Secemsky EA, Dowdy D, et al. Sudden cardiac death in patients with human immunodeficiency virus infection. J Am Coll Cardiol. 2012;59(21):1891–6. https://doi.org/10.1016/j.jacc.2012.02.024.CrossRefPubMedPubMedCentral

67.

Abudan AA, Vaidya VR, Tripathi B, et al. Burden of arrhythmia in hospitalized HIV patients. Clin Cardiol. 2021;44(1):66–77. https://doi.org/10.1002/clc.23506. ([published Online First: 20201209]).CrossRefPubMed

68.

Park DY, An S, Romero ME, et al. Incidence and risk factors of atrial fibrillation and atrial arrhythmias in people living with HIV: a systematic review and meta-analysis. J Interv Card Electrophysiol. 2022;65(1):183–91. https://doi.org/10.1007/s10840-022-01233-w. ([published Online First: 20220524]).CrossRefPubMed

69.

Hsu JC, Li Y, Marcus GM, et al. Atrial fibrillation and atrial flutter in human immunodeficiency virus-infected persons: incidence, risk factors, and association with markers of HIV disease severity. J Am Coll Cardiol. 2013;61(22):2288–95. https://doi.org/10.1016/j.jacc.2013.03.022. ([published Online First: 20130403]).CrossRefPubMed

70.

Myerson M, Kaplan-Lewis E, Poltavskiy E, Ferris D, Bang H. Prolonged QTc in HIV-infected patients: a need for routine ECG screening. J Int Assoc Provid AIDS Care. 2019;18:2325958219833926. https://doi.org/10.1177/2325958219833926.CrossRefPubMedPubMedCentral

71.

Bai YL, Liu HB, Sun B, et al. HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs. J Mol Cell Cardiol. 2011;51(5):876–80. https://doi.org/10.1016/j.yjmcc.2011.07.017. ([published Online First: 20110728]).CrossRefPubMed

72.

Boktor SW, Hafner JW. Influenza. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK459363/

73.

Nicholson KG. Human influenza. Textbook of Influenza 1998. https://www.cabdirect.org/cabdirect/abstract/19982013846

74.

Filgueiras-Rama D, Vasilijevic J, Jalife J, et al. Human influenza A virus causes myocardial and cardiac-specific conduction system infections associated with early inflammation and premature death. Cardiovasc Res. 2021;117(3):876–89. https://doi.org/10.1093/cvr/cvaa117.CrossRefPubMed

75.

Ukimura A, Izumi T, Matsumori A, Clinical Research Committee on Myocarditis Associated with Influenza APiJobJCS. A national survey on myocarditis associated with the 2009 influenza A (H1N1) pandemic in Japan. Circ J. 2010;74(10):2193–9. https://doi.org/10.1253/circj.cj-10-0452. ([published Online First: 20100806]).CrossRefPubMed

76.

Saraiya N, Singh S, Corpuz M. Fatal influenza myocarditis with incessant ventricular tachycardia. BMJ Case Rep. 2019;12(7). https://doi.org/10.1136/bcr-2018-228201.

77.

Frustaci A, Petrosillo N, Ippolito G, Chimenti C. Transitory ventricular tachycardia associated with influenza A infection of cardiac conduction tissue. Infection. 2016;44(3):353–6. https://doi.org/10.1007/s15010-016-0892-0. ([published Online First: 20160326]).CrossRefPubMed

78.

Gdynia G, Schnitzler P, Brunner E, et al. Sudden death of an immunocompetent young adult caused by novel (swine origin) influenza A/H1N1-associated myocarditis. Virchows Arch. 2011;458(3):371–6. https://doi.org/10.1007/s00428-010-1035-0. ([published Online First: 20110114]).CrossRefPubMed

79.

Ergle K, Gooden JY, Ahmed MM. High-grade atrioventricular block associated with acute influenza. Tex Heart Inst J. 2020;47(3):220–3. https://doi.org/10.14503/THIJ-18-6658.CrossRefPubMedPubMedCentral

80.

Rivera-Guzman N, Del Olmo-Arroyo F, Robles-Arias CM, Rodriguez-Cintron W. Transient AV block as a hemodynamic complication of the influenza A virus: a case report. P R Health Sci J. 2016;35(3):173–5.PubMed

81.

Engblom E, Ekfors TO, Meurman OH, Toivanen A, Nikoskelainen J. Fatal influenza A myocarditis with isolation of virus from the myocardium. Acta Med Scand. 1983;213(1):75–8. https://doi.org/10.1111/j.0954-6820.1983.tb03693.x.CrossRefPubMed

82.

Gokhroo RK, Barjaty HD, Bhawna K. Cardiac conduction system affection in a case of swine flu. J Assoc Physicians India. 2011;59:51–2.PubMed

83.

Chang TY, Chao TF, Liu CJ, et al. The association between influenza infection, vaccination, and atrial fibrillation: a nationwide case-control study. Heart Rhythm. 2016;13(6):1189–94. https://doi.org/10.1016/j.hrthm.2016.01.026. ([published Online First: 20160202]).CrossRefPubMed

84.

Madjid M, Connolly AT, Nabutovsky Y, Safavi-Naeini P, Razavi M, Miller CC. Effect of high influenza activity on risk of ventricular arrhythmias requiring therapy in patients with implantable cardiac defibrillators and cardiac resynchronization therapy defibrillators. Am J Cardiol. 2019;124(1):44–50. https://doi.org/10.1016/j.amjcard.2019.04.011. ([published Online First: 20190410]).CrossRefPubMed

85.

Braun DK, Dominguez G, Pellett PE. Human herpesvirus 6. Clin Microbiol Rev. 1997;10(3):521–67. https://doi.org/10.1128/CMR.10.3.521.CrossRefPubMedPubMedCentral

86.

Pantry SN, Medveczky PG. Latency, integration, and reactivation of human herpesvirus-6. Viruses 2017;9(7) https://doi.org/10.3390/v9070194 [published Online First: 20170724].

87.

Tschope C, Bock CT, Kasner M, et al. High prevalence of cardiac parvovirus B19 infection in patients with isolated left ventricular diastolic dysfunction. Circulation. 2005;111(7):879–86. https://doi.org/10.1161/01.CIR.0000155615.68924.B3. ([published Online First: 20050214]).CrossRefPubMed

88.

Kuhl U, Pauschinger M, Seeberg B, et al. Viral persistence in the myocardium is associated with progressive cardiac dysfunction. Circulation. 2005;112(13):1965–70. https://doi.org/10.1161/CIRCULATIONAHA.105.548156. ([published Online First: 20050919]).CrossRefPubMed

89.

Amin A, Taghavi S, Chenaghlou M, Zare E, Kamali M, Naderi N. Targeted treatment in viral-associated inflammatory cardiomyopathy. Clin Case Rep. 2021;9(7):e04518. https://doi.org/10.1002/ccr3.4518. ([published Online First: 20210723]).CrossRefPubMedPubMedCentral

90.

Yoshikawa T, Ihira M, Suzuki K, et al. Fatal acute myocarditis in an infant with human herpesvirus 6 infection. J Clin Pathol. 2001;54(10):792–5. https://doi.org/10.1136/jcp.54.10.792.CrossRefPubMedPubMedCentral

91.

Baranowski A, Buczynski M, Pajak J, et al. Fulminant herpes virus 6 myocarditis with complete atrioventricular block successfully treated with extracorporeal life support and ganciclovir. Kardiol Pol. 2020;78(12):1286–8. https://doi.org/10.33963/KP.15587. ([published Online First: 20200826]).CrossRefPubMed

92.

Chang YL, Parker ME, Nuovo G, Miller JB. Human herpesvirus 6-related fulminant myocarditis and hepatitis in an immunocompetent adult with fatal outcome. Hum Pathol. 2009;40(5):740–5. https://doi.org/10.1016/j.humpath.2008.08.017. ([published Online First: 20090113]).CrossRefPubMed

93.

Nishimoto M, Nakamae H, Hayashi Y, et al. Prolonged sinus tachycardia caused by human herpesvirus 6 (HHV6) encephalomyelitis after allogeneic bone marrow transplantation. Intern Med. 2012;51(10):1265–7. https://doi.org/10.2169/internalmedicine.51.6640. ([published Online First: 20120515]).CrossRefPubMed

94.

Macri A, Crane JS. Parvoviruses. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK482245/

95.

Tscholl V, Wielander D, Kelch F, et al. Benefit of a wearable cardioverter defibrillator for detection and therapy of arrhythmias in patients with myocarditis. ESC Heart Fail. 2021;8(4):2428–37. https://doi.org/10.1002/ehf2.13353. ([published Online First: 20210422]).CrossRefPubMedPubMedCentral

96.

Adda J, Machado S, Eberst E, Roubille C, Macia JC, Roubille F. Parvovirus B19 infection and acute myocarditis. Intern Med. 2010;49(1):79. https://doi.org/10.2169/internalmedicine.49.2606. ([published Online First: 20100101]).CrossRefPubMed

97.

Pesce R, Taffarello P, Rizzo S, et al. Fulminant myocarditis parvovirus B19 related in a young woman. J Artif Organs. 2021;24(4):498–502. https://doi.org/10.1007/s10047-021-01247-7. ([published Online First: 20210124]).CrossRefPubMedPubMedCentral

98.

Koehl B, Oualha M, Lesage F, et al. Fatal parvovirus B19 myocarditis in children and possible dysimmune mechanism. Pediatr Infect Dis J. 2012;31(4):418–21. https://doi.org/10.1097/INF.0b013e3182425786.CrossRefPubMed

99.

Munro K, Croxson MC, Thomas S, Wilson NJ. Three cases of myocarditis in childhood associated with human parvovirus (B19 virus). Pediatr Cardiol. 2003;24(5):473–5. https://doi.org/10.1007/s00246-002-0173-9.CrossRefPubMed

100.

Dina J, Vabret A, Rambaud C, et al. Fulminant myocarditis associated with parvovirus B19 infection in a child. J Clin Virol. 2008;42(1):70–1. https://doi.org/10.1016/j.jcv.2007.12.018. ([published Online First: 20080229]).CrossRefPubMed

101.

Buob A, Siaplaouras S, Janzen I, et al. Focal parvovirus B19 myocarditis in a patient with Brugada syndrome. Cardiol Rev. 2003;11(1):45–9. https://doi.org/10.1097/00045415-200301000-00009.CrossRefPubMed

102.

Juhasz Z, Tiszlavicz L, Kele B, et al. Sudden cardiac death from parvovirus B19 myocarditis in a young man with Brugada syndrome. J Forensic Leg Med. 2014;25:8–13. https://doi.org/10.1016/j.jflm.2014.04.018. ([published Online First: 20140429]).CrossRefPubMed

103.

Chia JK, Jackson B. Myopericarditis due to parvovirus B19 in an adult. Clin Infect Dis. 1996;23(1):200–1. https://doi.org/10.1093/clinids/23.1.200.CrossRefPubMed

104.

Mathew Jr J, Sapra A. Herpes simplex type 2. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK554427/

105.

Saleh D, Yarrarapu SNS, Sharma S. Herpes simplex type 1. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK482197/

106.

Chaabane S, Harfouche M, Chemaitelly H, Schwarzer G, Abu-Raddad LJ. Herpes simplex virus type 1 epidemiology in the Middle East and North Africa: systematic review, meta-analyses, and meta-regressions. Sci Rep. 2019;9(1):1136. https://doi.org/10.1038/s41598-018-37833-8. ([published Online First: 20190204]).CrossRefPubMedPubMedCentral

107.

Bradley H, Markowitz LE, Gibson T, McQuillan GM. Seroprevalence of herpes simplex virus types 1 and 2–United States, 1999–2010. J Infect Dis. 2014;209(3):325–33. https://doi.org/10.1093/infdis/jit458. ([published Online First: 20131016]).CrossRefPubMed

108.

Colombo D, Albore M, Nonno FD, et al. Fatal fulminant HSV-2 myocarditis: a complicated presentation. Int J Infect Dis. 2022;114:124–7. https://doi.org/10.1016/j.ijid.2021.10.046. ([published Online First: 20211027]).CrossRefPubMed

109.

Koga M, Fujiwara M, Ariga S, et al. CD8+ T-lymphocytes infiltrate the myocardium in fulminant herpes virus myocarditis. Pediatr Pathol Mol Med. 2001;20(3):189–95.CrossRefPubMed

110.

Smith BK, Cook MJ, Prior DL. Sinus node arrest secondary to HSV encephalitis. J Clin Neurosci. 2008;15(9):1053–6. https://doi.org/10.1016/j.jocn.2006.06.017. ([published Online First: 20070323]).CrossRefPubMed

111.

Braiman D, Konstantino Y, Westreich R. When the brain slows the heart-herpes encephalitis and sinus arrest: a case report. Eur Heart J Case Rep. 2021;5(8):ytab254. https://doi.org/10.1093/ehjcr/ytab254. ([published Online First: 20210802]).CrossRefPubMedPubMedCentral

112.

Alsolaiman MM, Alsolaiman F, Bassas S, Amin DK. Viral encephalitis associated with reversible asystole due to sinoatrial arrest. South Med J. 2001;94(5):540–1.CrossRefPubMed

113.

Nicol PP TJ, Joseph T. Herpes simplex encephalitis, an unusual cause of sinus node dysfunction: case report and literature review. Int J Clin Cardiol 2015;2(4) https://doi.org/10.23937/2378-2951/1410042.

114.

Pollock S, Reid H, Klapper P, Metcalfe RA, Ahmed N. Herpes simplex encephalitis presenting as the sick sinus syndrome. J Neurol Neurosurg Psychiatry. 1986;49(3):331–2. https://doi.org/10.1136/jnnp.49.3.331-a.CrossRefPubMedPubMedCentral

115.

Chiang CH, Huang CC, Chan WL, et al. Herpes simplex virus infection and risk of atrial fibrillation: a nationwide study. Int J Cardiol. 2013;164(2):201–4. https://doi.org/10.1016/j.ijcard.2011.06.126. ([published Online First: 20110722]).CrossRefPubMed

116.

Gupta M, Shorman M. Cytomegalovirus. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK459185/

117.

Zheng QY, Huynh KT, van Zuylen WJ, Craig ME, Rawlinson WD. Cytomegalovirus infection in day care centres: a systematic review and meta-analysis of prevalence of infection in children. Rev Med Virol. 2019;29(1):e2011. https://doi.org/10.1002/rmv.2011. ([published Online First: 20181010]).CrossRefPubMed

118.

Nosotti M, Tarsia P, Morlacchi LC. Infections after lung transplantation. J Thorac Dis. 2018;10(6):3849–68. https://doi.org/10.21037/jtd.2018.05.204.CrossRefPubMedPubMedCentral

119.

Cannon MJ, Schmid DS, Hyde TB. Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection. Rev Med Virol. 2010;20(4):202–13. https://doi.org/10.1002/rmv.655.CrossRefPubMed

120.

Kyto V, Vuorinen T, Saukko P, et al. Cytomegalovirus infection of the heart is common in patients with fatal myocarditis. Clin Infect Dis. 2005;40(5):683–8. https://doi.org/10.1086/427804. ([published Online First: 20050204]).CrossRefPubMed

121.

Roubille C, Brunel AS, Gahide G, Vernhet Kovacsik H, Le Quellec A. Cytomegalovirus (CMV) and acute myocarditis in an immunocompetent patient. Intern Med. 2010;49(2):131–3. https://doi.org/10.2169/internalmedicine.49.2313. ([published Online First: 20100115]).CrossRefPubMed

122.

Vanstechelman F, Vandekerckhove H. Cytomegalovirus myocarditis in an immunocompetent patient. Acta Cardiol. 2012;67(2):257–60. https://doi.org/10.1080/ac.67.2.2154221.CrossRefPubMed

123.

Padala SK, Kumar A, Padala S. Fulminant cytomegalovirus myocarditis in an immunocompetent host: resolution with oral valganciclovir. Tex Heart Inst J. 2014;41(5):523–9. https://doi.org/10.14503/THIJ-13-3504. ([published Online First: 20141001]).CrossRefPubMedPubMedCentral

124.

Waris E, Rasanen O, Kreus KE, Kreus R. Fatal cytomegalovirus disease in a previously healthy adult. Scand J Infect Dis. 1972;4(1):61–7. https://doi.org/10.3109/inf.1972.4.issue-1.13.CrossRefPubMed

125.

Dietz AJ Jr. Cytomegalovirus infection with carditis, hepatitis, and anemia. Postgrad Med. 1981;70(3):203–8. https://doi.org/10.1080/00325481.1981.11715865.CrossRefPubMed

126.

Wilson RS, Morris TH, Rees JR. Cytomegalovirus myocarditis. Br Heart J. 1972;34(8):865–8. https://doi.org/10.1136/hrt.34.8.865.CrossRefPubMedPubMedCentral

127.

McCormack JG, Bowler SD, Donnelly JE, Steadman C. Successful treatment of severe cytomegalovirus infection with ganciclovir in an immunocompetent host. Clin Infect Dis. 1998;26(4):1007–8. https://doi.org/10.1086/517635.CrossRefPubMed

128.

Dilaveris P, Dimitriadis K, Lazaros G, Gatzoulis K, Stefanadis C. Cytomegalovirus infection: a potential threat to atrioventricular conduction? Am J Med. 2010;123(8):e3-4. https://doi.org/10.1016/j.amjmed.2009.12.036.CrossRefPubMed

129.

Mulder TJ, Niyazov DM, Kattash MM, Longo SA, Robichaux Iii AG, Snyder CS. A newborn with congenital complete atrioventricular block, lissencephaly, and skeletal abnormalities: a case of suspected cytomegalovirus infection. Congenit Heart Dis. 2010;5(5):486–90. https://doi.org/10.1111/j.1747-0803.2010.00390.x.CrossRefPubMed

130.

Lewis PE 2nd, Cefalo RC, Zaritsky AL. Fetal heart block caused by cytomegalovirus. Am J Obstet Gynecol. 1980;136(7):967–8. https://doi.org/10.1016/0002-9378(80)91064-9.CrossRefPubMed

131.

Karn K, Julian TM, Ogburn PL Jr. Fetal heart block associated with congenital cytomegalovirus infection A case report. J Reprod Med. 1984;29(4):278–80.PubMed

132.

Lee KH, Yoo SG, Han KD, La Y, Kwon DE, Han SH. Association of cytomegalovirus diseases with newly developed myocardial infarction and congestive heart failure: data from a national population-based cohort. Arch Med Sci. 2022;18(5):1188–98. https://doi.org/10.5114/aoms/105157. ([published Online First: 20210319]).CrossRefPubMed

133.

Hoover K, Higginbotham K. Epstein Barr virus. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK559285/

134.

List AF, Greco FA, Vogler LB. Lymphoproliferative diseases in immunocompromised hosts: the role of Epstein-Barr virus. J Clin Oncol. 1987;5(10):1673–89. https://doi.org/10.1200/JCO.1987.5.10.1673.CrossRefPubMed

135.

Sasko B, Patschan D, Nordbeck P, et al. Secondary prevention of potentially life-threatening arrhythmia using implantable cardioverter defibrillators in patients with biopsy-proven viral myocarditis and preserved ejection fraction. Cardiology. 2021;146(2):213–21. https://doi.org/10.1159/000511120. ([published Online First: 20210205]).CrossRefPubMed

136.

Mavrogeni S, Spargias K, Bratis C, Kolovou G, Papadopoulou E, Pavlides G. EBV infection as a cause of VT: evaluation by CMR. JACC Cardiovasc Imaging. 2011;4(5):561–2. https://doi.org/10.1016/j.jcmg.2010.11.022.CrossRefPubMed

137.

Watanabe M, Panetta GL, Piccirillo F, et al. Acute Epstein-Barr related myocarditis: an unusual but life-threatening disease in an immunocompetent patient. J Cardiol Cases. 2020;21(4):137–40. https://doi.org/10.1016/j.jccase.2019.12.001. ([published Online First: 20191226]).CrossRefPubMed

138.

Aghenta A, Osowo A, Thomas J. Symptomatic atrial fibrillation with infectious mononucleosis. Can Fam Physician. 2008;54(5):695–6.PubMedPubMedCentral

139.

Takano H, Nakagawa K, Ishio N, et al. Active myocarditis in a patient with chronic active Epstein-Barr virus infection. Int J Cardiol. 2008;130(1):e11–3. https://doi.org/10.1016/j.ijcard.2007.07.040. ([published Online First: 20071025]).CrossRefPubMed

140.

Reitman MJ, Zirin HJ, DeAngelis CJ. Complete heart block in Epstein-Barr myocarditis. Pediatrics. 1978;62(5):847–9.CrossRefPubMed

141.

Leis P, Correa A, Setareh-Shenas S, Paka P, Mehta D. A heart-stopping encounter: a case of complete heart block from Epstein-Barr virus-associated myocarditis. J Am Coll Cardiol. 2020;75(11):2841–941. https://doi.org/10.1016/S0735-1097(20)33468-9.CrossRef

142.

Ayoade F, Kumar S. Varicella Zoster. StatPearls. Treasure Island (FL), 2022. https://www.ncbi.nlm.nih.gov/books/NBK448191/

143.

Ioannou A, Tsappa I, Metaxa S, Missouris CG. Ventricular fibrillation following varicella zoster myocarditis. Case Rep Cardiol. 2017;2017:1017686. https://doi.org/10.1155/2017/1017686. ([published Online First: 20171123]).CrossRefPubMedPubMedCentral

144.

Fiddler GI, Campbell RW, Pottage A, Godman MJ. Varicella myocarditis presenting with unusual ventricular arrhythmias. Br Heart J. 1977;39(10):1150–3. https://doi.org/10.1136/hrt.39.10.1150.CrossRefPubMedPubMedCentral

145.

Dennison P, Zaremba E. Varicella zoster induced cardiac dysfunction: a case report. Emerg Med J. 2007;24(9):682–3. https://doi.org/10.1136/emj.2006.034280.CrossRefPubMedPubMedCentral

146.

Nurnberg JH, Senft G, Sperling P, Lange PE. A delayed life-threatening complication after uneventful varicella infection: transient complete heart block. Klin Padiatr. 2002;214(3):113–6. https://doi.org/10.1055/s-2002-30145.CrossRefPubMed

147.

Rich R, McErlean M. Complete heart block in a child with varicella. Am J Emerg Med. 1993;11(6):602–5. https://doi.org/10.1016/0735-6757(93)90011-y.CrossRefPubMed

148.

Ettedgui JA, Ladusans E, Bamford M. Complete heart block as a complication of varicella. Int J Cardiol. 1987;14(3):362–5. https://doi.org/10.1016/0167-5273(87)90208-7.CrossRefPubMed

149.

Katsuta T, Kato H, Kaneko Y, et al. Complete atrioventricular block as a complication of varicella in children. Pediatr Infect Dis J. 2011;30(5):445–6. https://doi.org/10.1097/INF.0b013e3182011286.CrossRefPubMed

150.

Uysal F, Bostan OM, Cetin B, Uysal B, Guney B, Cil E. Complete atrioventricular block as a complication of varicella infection in a child: recovery with a single dose of intravenous immunoglobulin therapy. Clin Pediatr (Phila). 2016;55(7):677–9. https://doi.org/10.1177/0009922816629617. ([published Online First: 20160217]).CrossRefPubMed

151.

Cha M-J, Seo H-M, Choi E-K, et al. Increased risk of atrial fibrillation in the early period after herpes zoster infection: a nationwide population-based case-control study. Jkms. 2018;33(22):0–0. https://doi.org/10.3346/jkms.2018.33.e160.CrossRef

Titel: Cardiac arrhythmias in viral infections
verfasst von: Paul Y. Lee
Hasan Garan
Elaine Y. Wan
Brian E. Scully
Angelo Biviano
Hirad Yarmohammadi
Publikationsdatum: 16.03.2023
Verlag: Springer US
Erschienen in: Journal of Interventional Cardiac Electrophysiology / Ausgabe 8/2023
Print ISSN: 1383-875X
Elektronische ISSN: 1572-8595
DOI: https://doi.org/10.1007/s10840-023-01525-9

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Cardiac arrhythmias in viral infections

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Background

Methods and results

Conclusions

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Methods and results

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