Skip to main content

Clinical Pharmacokinetics

Ausgabe 4/2024

Inhalt (10 Artikel)

Open Access Review Article

Clinical Pharmacokinetics and Pharmacodynamics of Naloxone

Teijo I. Saari, John Strang, Ola Dale

Open Access Review Article

Clinical Pharmacology of the Antibody–Drug Conjugate Enfortumab Vedotin in Advanced Urothelial Carcinoma and Other Malignant Solid Tumors

Mei Tang, Amit Garg, Peter L. Bonate, Jonathan E. Rosenberg, Maria Matsangou, Takeshi Kadokura, Akihiro Yamada, Mary Choules, Janet Pavese, Masanori Nagata, Daisuke Tenmizu, Akira Koibuchi, Nakyo Heo, Lu Wang, Tomasz Wojtkowski, William D. Hanley, Srinivasu Poondru

Systematic Review

Have We Neglected to Study Target-Site Drug Exposure in Children? A Systematic Review of the Literature

Eline Hermans, Jozefien Meersschaut, Isis Van herteryck, Mathias Devreese, Johan Vande Walle, Peter De Paepe, Pieter A. De Cock

Open Access Original Research Article

Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers

Brit S. Rohr, Evelyn Krohmer, Kathrin I. Foerster, Jürgen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter E. Haefeli

Open Access Original Research Article

Clinical Evaluation of the Effect of Encorafenib on Bupropion, Rosuvastatin, and Coproporphyrin I and Considerations for Statin Coadministration

Joseph Piscitelli, Micaela B. Reddy, Lance Wollenberg, Laurence Del Frari, Jason Gong, Linda Wood, Yizhong Zhang, Kyle Matschke, Jason H. Williams

Open Access Original Research Article

Dosing of Convalescent Plasma and Hyperimmune Anti-SARS-CoV-2 Immunoglobulins: A Phase I/II Dose-Finding Study

Sammy Huygens, Tim Preijers, Francis H. Swaneveld, Ilona Kleine Budde, Corine H. GeurtsvanKessel, Birgit C. P. Koch, Bart J. A. Rijnders

Open Access Original Research Article

Demonstrating Bioequivalence for Two Dose Strengths of Niraparib and Abiraterone Acetate Dual-Action Tablets Versus Single Agents: Utility of Clinical Study Data Supplemented with Modeling and Simulation

Alex Yu, Anasuya Hazra, James Juhui Jiao, Peter Hellemans, Anna Mitselos, Hui Tian, Juan Jose Perez Ruixo, Nahor Haddish-Berhane, Daniele Ouellet, Alberto Russu

Open Access Original Research Article

Performance of Eight Infliximab Population Pharmacokinetic Models in a Cohort of Dutch Children with Inflammatory Bowel Disease

Nanja C. Bevers, Ron J. Keizer, Dennis R. Wong, Arta Aliu, Marieke J. Pierik, Luc J. J. Derijks, Patrick F. van Rheenen

Original Research Article

Optimization of Ganciclovir and Valganciclovir Starting Dose in Children by Machine Learning

Laure Ponthier, Julie Autmizguine, Benedicte Franck, Anders Åsberg, Philippe Ovetchkine, Alexandre Destere, Pierre Marquet, Marc Labriffe, Jean-Baptiste Woillard

Open Access Original Research Article

Population Pharmacodynamic Dose–Response Analysis of Serum Potassium Following Dosing with Sodium Zirconium Cyclosilicate

Robert C. Penland, Magnus Åstrand, David W. Boulton, Mats Någård