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Pediatric Surgery International

Erschienen in:

01.12.2023 | Original Article

Correlation of ectopic distal location of papilla of Vater and clinical characteristics in pediatric choledochal cysts

verfasst von: Suyun Chen, Tong Yin, Long Li, Mei Diao, Ting Huang

Erschienen in: Pediatric Surgery International | Ausgabe 1/2023

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Abstract

Purpose

Ectopic distal location of papilla of Vater (EDLPV) is an obvious pathological feature of choledochal cyst (CDC). This study aimed to investigate the correlation between EDLPV and clinical characteristics of CDCs.

Methods

Three groups were studied: Group 1 (G1), papilla in the middle third of second part of duodenum (n = 38); Group 2 (G2), papilla from the distal third of second part to the beginning of third part of duodenum (n = 168); Group 3 (G3), papilla from the middle of third part to fourth part of duodenum (n = 121). Relative variables among three groups were compared.

Results

Compared with G1 and G2, G3 patients had the largest cysts (relative diameter: 1.18 vs. 1.60 vs. 2.62, p < 0.001), the youngest age (20.52 vs. 19.47 vs. -3.40 months, p < 0.001), the highest rate of prenatal diagnosis (26.32% vs. 36.31% vs. 62.81%, p < 0.001), the lowest occurrence of protein plugs in common channel (44.74% vs. 38.69% vs. 16.53%, p < 0.001), and the most elevated total bilirubin level (7.35 vs. 9.95 vs. 28.70 μmol/L, p < 0.001). Prenatally diagnosed G3 patients had heavier liver fibrosis than G2 (13.16% vs. 1.67%, p = 0.015).

Conclusion

The more distal papilla location, the more severe clinical characteristics of CDCs, suggesting a crucial role in its pathogenesis.

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Titel: Correlation of ectopic distal location of papilla of Vater and clinical characteristics in pediatric choledochal cysts
verfasst von: Suyun Chen
Tong Yin
Long Li
Mei Diao
Ting Huang
Publikationsdatum: 01.12.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Surgery International / Ausgabe 1/2023
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-023-05486-y

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Correlation of ectopic distal location of papilla of Vater and clinical characteristics in pediatric choledochal cysts

Abstract

Purpose

Methods

Results

Conclusion

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