07.05.2024 | Substantive Review
COVID-19 Vaccine Acceptance and Hesitancy among People Living with HIV: Review and Meta-Analysis
verfasst von:
Marcos Pereira, Italo Ricardo Santos Aleluia, Caroline Tianeze de Castro, Tarcio de Almeida Oliveira, Mila Silva Cunha, Laio Magno, Inês Dourado, Florisneide Barreto, Marcio Natividade, Seth Christopher Yaw Appiah, Erick Abade, Enny S. Paixao, Maria Lidiany Tributino de Souza
Erschienen in:
AIDS and Behavior
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Abstract
This study aims to estimate the COVID-19 vaccine acceptance and hesitancy among people living with HIV (PLWHA). A search for observational studies was conducted in five databases and preprinted literature. Summary estimates were pooled using a random effects model and meta-regression. Of 150 identified studies, 31 were eligible (18,550 PLWHA). The weighted prevalence of COVID-19 vaccine hesitancy overall was 29.07% among PLWHA (95%CI = 24.33–34.32; I² = 98%,) and that of vaccine acceptance was 68.66% (95%CI = 62.25–74.43; I² = 98%). Higher hesitancy prevalence was identified in low/lower-middle income countries (35.05; 95% CI = 19.38–54.78). The heterogeneity was explained by the risk of bias, region, and year of data collection. The findings conclude that the COVID-19 vaccine hesitancy rate remains high, especially in low-income countries. Evidence-informed interventions aimed at increasing COVID-19 vaccine acceptance at the national and individual levels ought to be designed to increase COVID-19 vaccine acceptance among PLWHA.