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12.06.2023 | Review Article

Effects of grating stimulation on vision in individuals with amblyopia: a systematic review and meta-analysis

verfasst von: Wen-Hsiu Yeh, Ya-Ju Ju, Tzu-Han Hsieh, Yu-Ting Liu

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 2/2024

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Abstract

Purpose

To investigate the effects of Cambridge Stimulator with grating element stimulation on visual acuity (VA), grating acuity (GA), and contrast sensitivity (CS) in patients with amblyopia.

Methods

Three electronic databases (PubMed, Embase, and Cochrane Library) were searched for studies published from January 1970 to November 2022. The searched studies were reviewed and extracted independently by two authors. The included studies were evaluated by the Cochrane risk of bias. A meta-analysis calculating Hedges’ g effect-size metric with 95% confidence intervals using random-effects DerSimonian-Laird model was employed. Heterogeneity was estimated using I² statistics. Outcomes of interest included VA, GA, and CS.

Results

A total of 1221 studies were identified. Twenty-four studies including 900 subjects met the inclusion criteria. The outcome measure of all visual indexes (VA: Hedges’ g of − 0.43, 95% CI = − 0.81 to − 0.05, I² = 86%, p = 0.02; GA: Hedges’ g of 3.79, 95% CI = 1.05 to 6.54, I² = 98%, p = 0.01; CS: Hedges’ g of 0.64, 95% CI = 0.19 to 1.09, I² = 41%, p = 0.00) significantly favored in the grating group.

Conclusions

Grating stimulation may be a positive help for visual functions in patients with amblyopia. The effects of grating stimulation on VA and CS appear to be opposite. This study is registered with www.crd.york.ac.uk/prospero/ (CRD42022366259).

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Titel: Effects of grating stimulation on vision in individuals with amblyopia: a systematic review and meta-analysis
verfasst von: Wen-Hsiu Yeh
Ya-Ju Ju
Tzu-Han Hsieh
Yu-Ting Liu
Publikationsdatum: 12.06.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 2/2024
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-023-06142-w

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