Erschienen in:
01.03.2010 | Short Communication
Expression and function of histamine H4 receptor in mouse splenic dendritic cells
verfasst von:
T. Simon, I. Jelinek, Gy. Apponyi, V. László, É. Rajnavölgyi, A. Falus
Erschienen in:
Inflammation Research
|
Sonderheft 2/2010
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Excerpt
Dendritic cells (DC) are the master regulators of the immune system. DCs act as “sentinels” and they are the most potent antigen-presenting cells specialized for capture, transport, processing and presentation of antigens [
1]. During these activities numerous factors may influence their functions. Histamine is one of these mediators released from neighboring mast cells, basophils, and even from the DCs themselves [
2]. …