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2016 | OriginalPaper | Buchkapitel

17. Grundlagen natürlicher Allergene

verfasst von : H. Breiteneder, Prof. Dr. rer. nat.

Erschienen in: Allergologie

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Die scheinbar große Anzahl von Allergenen lässt sich mittels struktureller Kriterien in ein gut überschaubares System einordnen. Die wichtigsten Allergene pflanzlichen und tierischen Ursprungs können so 8 Proteinsuperfamilien zugeordnet werden. Diese werden in diesem Kapitel vorgestellt. Biochemische, biologische und allergene Eigenschaften sowie Kreuzreaktivitäten ausgewählter Allergene dieser Gruppierungen werden besprochen. Übersichtliche Tabellen zeigen zahlreiche Beispiele allergener Vertreter für jede der 8 Superfamilien. Die hier vorgestellte Klassifizierung liefert eine Grundlage für weitere Überlegungen zur Fähigkeit dieser Proteine, eine allergische Sensibilisierung zu verursachen. Diese scheint u. a. auch mit der Fähigkeit, dass Allergene Liganden binden und mit dem angeborenen Immunsystem interagieren können, verknüpft zu sein, wie in diesem Kapitel abschließend diskutiert wird.
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Metadaten
Titel
Grundlagen natürlicher Allergene
verfasst von
H. Breiteneder, Prof. Dr. rer. nat.
Copyright-Jahr
2016
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-37203-2_17

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