nach oben

12.09.2023 | Original Article

Hepatitis C co-infection characteristics and correlates in newly reported HIV/AIDS patients in Southwest China, 2018–2022

verfasst von: Yulian Zhang, Chunnong Jike, Gang Yu, Ju Wang, Zhonghong Wang, Lazuo Ma, Tianlu Li, Yuan Li, Rong Pei

Einloggen, um Zugang zu erhalten

Abstract

Aims

The aims of the project were: (1) to map the current HIV–HCV co-infection in Liangshan Prefecture, Sichuan Province, China, (2) to explore the risk factors of HIV–HCV co-infection in Liangshan Prefecture, and (3) to propose strategies for prevention and control of HIV–HCV co-infection in Liangshan Prefecture.

Subject and methods

This study assessed the HIV–HCV co-infection rate, characteristics, and correlative factors of HIV–HCV co-infection individuals reported between 2018 and 2022 in Liangshan. This made use of path analysis, multiple logistic regression analysis, and chi-square tests.

Results

The findings revealed a 6.75% HIV–HCV co-infection rate, and the incidence was stable from 2018 to 2022. The outcomes of multiple logistic regression showed the correlative factors, including male (OR = 2.640, 95% CI: 2.300–3.031), 25–44 years (OR = 4.184, 95% CI: 2.135–8.196), 45–64 years (OR = 3.411, 95% CI: 1.733–0.937), Anning River Valley (OR = 2.583, 95% CI: 1.833–3.639) and east of it (OR = 2.543, 95% CI: 1.749–3.699), and injecting drug use (OR = 2.116, 95% CI: 1.879–2.383). The pathway analysis revealed that co-infection was directly influenced by gender (−0.112), ethnicity (−0.079), marital status (0.077), and route of infection (−0.095).

Conclusion

Concentrate on the high-risk group based on the co-infection associated factors found in the study's findings. Take the necessary steps to enhance patient quality of life and survival, as well as the efficacy of preventive treatment and therapy.

newly reported HIV/AIDS infections, includes new infections this year, as well as previous infections reported to the China's HIV/AIDS Comprehensive Response Information Management System for the first time this year.

newly reported HCV infections, includes new infections this year, as well as previous infections reported to the China's Hepatitis C Control Information System for the first time this year.

Akhtar A, Fatima S, Saeed H, Soo CT, Khan AH (2022) HIV–HCV coinfection: prevalence and treatment outcomes in Malaysia. Intervirology 65(2):87–93. https://doi.org/10.1159/000518836CrossRefPubMed

Alter MJ (2006) Epidemiology of viral hepatitis and HIV co-infection. J Hepatol 44(1 Suppl):S6–S9. https://doi.org/10.1016/j.jhep.2005.11.004CrossRefPubMed

Azar MM, Springer SA, Meyer JP, Altice FL (2010) A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization. Drug Alcohol Depend 112(3):178–193. https://doi.org/10.1016/j.drugalcdep.2010.06.014CrossRefPubMedPubMedCentral

Bhattarai M, Baniya JB, Aryal N, Shrestha B, Rauniyar R, Adhikari A, Koirala P, Oli PK, Pandit RD, Stein DA, Gupta BP (2018) Epidemiological profile and risk factors for acquiring HBV and/or HCV in HIV-Infected population groups in Nepal. Biomed Res Int 2018:9241679. https://doi.org/10.1155/2018/9241679CrossRefPubMedPubMedCentral

Carrieri MP, Serfaty L, Vilotitch A, Winnock M, Poizot-Martin I, Loko MA, Lions C, Lascoux-Combe C, Roux P, Salmon-Ceron D, Spire B, Dabis F (2015) Cannabis use and reduced risk of insulin resistance in HIV–HCV infected patients: a longitudinal analysis (ANRS CO13 HEPAVIH). Clin Infect Dis 61(1):40–48. https://doi.org/10.1093/cid/civ217CrossRefPubMed

Chinese Center for Disease Control and Prevention (2021) General situation of notifiable infectious diseases in China in 2020. https://www.nhc.gov.cn/jkj/s3578/202103/f1a448b7df7d4760976fea6d55834966.shtml. Accessed 2 Nov 2022

Chinese Center for Disease Control and Prevention (2022) Leading the way in AIDS prevention, attacking multiple diseases — Liangshan Prefecture AIDS and other major infectious diseases prevention and treatment expert group and workstation regular meeting held in Xichang. https://ncaids.chinacdc.cn/zxzx/zxdteff/202208/t20220801_260633.htm. Accessed 15 Aug 2023

Cooke GS, Andrieux-Meyer I, Applegate TL, Atun R, Burry JR, Cheinquer H, Dusheiko G, Feld JJ, Gore C, Griswold MG, Hamid S, Hellard ME, Hou J, Howell J, Jia J, Kravchenko N, Lazarus JV, Lemoine M, Lesi OA et al (2019) Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission. Lancet Gastroenterol Hepatol 4(2):135–184. https://doi.org/10.1016/s2468-1253(18)30270-xCrossRefPubMed

Danhui Y (2008) Structural equation modeling: methods and applications. Renmin University of China Press, Beijing, China, pp 4–9

Fanciulli C, Berenguer J, Busca C, Vivancos MJ, Tellez MJ, Dominguez L, Domingo P, Navarro J, Santos J, Iribarren A, Morano L, Artero A, Moreno J, Rivero-Roman A, Santos I, Giner L, Arminanzas C, Montero M, Manzardo C et al (2022) Epidemiological trends of HIV/HCV coinfection in Spain, 2015–2019. Hiv Med 23(7):705–716. https://doi.org/10.1111/hiv.13229CrossRefPubMedPubMedCentral

Gang Y, Tianlu L, Zhonghong W, Nengar A, Shama T, Jik C, Shujuan Y (2021) Characteristics analysis of newly reported HIV/AIDS patients in Liangshan Prefecture, 2017–2019. Chin J AIDS & STD 27(10):1152–1153. https://doi.org/10.13419/j.cnki.aids.2021.10.24CrossRef

Giordano TP, Kramer JR, Souchek J, Richardson P, El-Serag HB (2004) Cirrhosis and hepatocellular carcinoma in HIV-infected veterans with and without the hepatitis C virus: a cohort study, 1992–2001. Arch Intern Med 164(21):2349–2354. https://doi.org/10.1001/archinte.164.21.2349CrossRefPubMed

Hu L t, Bentler PM (1999) Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Eq Model: Multidisciplin J 6(1):1–55. https://doi.org/10.1080/10705519909540118CrossRef

Joshi D, O'Grady J, Dieterich D, Gazzard B, Agarwal K (2011) Increasing burden of liver disease in patients with HIV infection. Lancet 377(9772):1198–1209. https://doi.org/10.1016/s0140-6736(10)62001-6CrossRefPubMed

Lei L, Liansheng Z, Heng T, Ying W, Honglin J (2014) Research progress on risk factors of Hepatitis C virus infection. Modern Prev Med 41(06):1115–1117

Lu Y, Tang S, Qin Y, Harypursat V, Wu H, Chen Y (2022) Changes of human immunodeficiency virus (HIV) burden globally and in China over three decades: a secondary analysis of global HIV statistics. Chin Med J 135(22):2690–2698. https://doi.org/10.1097/cm9.0000000000002500CrossRefPubMedPubMedCentral

Lunhao L, Li L, Gang Y, Li L, Xiaodi P, Fengsun Y (2018) Epidemic characteristics and trend among newly reported HIV cases in Liangshan prefecture during 2005–2016. Chin J AIDS & STD 24(4):345–347+356. https://doi.org/10.13419/j.cnki.aids.2018.04.08CrossRef

MacCallum RC, Browne MW, Sugawara HM (1996) Power analysis and determination of sample size for covariance structure modeling. Psychol Methods 1(2):130–149. https://doi.org/10.1037/1082-989X.1.2.130CrossRef

Mattingly T, Joseph I, Pandit NS, Eberechukwu O (2019) Burden of co-infection: a cost analysis of human immunodeficiency virus in a commercially insured Hepatitis C virus population. Infect Diseases Ther 8(2):219–228. https://doi.org/10.1007/s40121-019-0240-7CrossRef

McKee G, Butt ZA, Wong S, Salway T, Gilbert M, Wong J, Alvarez M, Chapinal N, Darvishian M, Tyndall MW, Krajden M, Janjua NZ (2018) Syndemic characterization of HCV, HBV, and HIV co-infections in a large population based cohort study. EClinicalMedicine 4-5:99–108. https://doi.org/10.1016/j.eclinm.2018.10.006CrossRefPubMedPubMedCentral

Meiying W (2018) Dietary custom of the Yis in Liangshan and its cultural representatio. J Yunnan Minzu Univ(Philos Social Sci Edition) 35(5):55–61. https://doi.org/10.13727/j.cnki.53-1191/c.2018.05.009CrossRef

Morano JP, Gibson BA, Altice FL (2013) The burgeoning HIV/HCV syndemic in the urban Northeast: HCV, HIV, and HIV/HCV coinfection in an urban setting. PLoS One 8(5):e64321. https://doi.org/10.1371/journal.pone.0064321CrossRefPubMedPubMedCentral

Operskalski EA, Kovacs A (2011) HIV/HCV co-infection: pathogenesis, clinical complications, treatment, and new therapeutic technologies. Curr HIV/AIDS Rep 8(1):12–22. https://doi.org/10.1007/s11904-010-0071-3CrossRefPubMedPubMedCentral

Pengyan L, Caiting D, Mengran D, Hongxia D, Jun H, Qi X, Wen Y, Jianxin Z (2016) Knowledge, attitude and practice about sex among middle school students of Yi minority. Chin J Public Health 32(02):222–224. https://doi.org/10.11847/zgggws2016-32-02-26CrossRef

Platt L, Easterbrook P, Gower E, McDonald B, Sabin K, McGowan C, Yanny I, Razavi H, Vickerman P (2016) Prevalence and burden of HCV co-infection in people living with HIV: a global systematic review and meta-analysis [Review]. Lancet Infectious Diseases 16(7):797–808. https://doi.org/10.1016/s1473-3099(15)00485-5CrossRefPubMed

Rockstroh JK (2003) Management of hepatitis B and C in HIV co-infected patients. J Acquir Immune Defic Syndr 34(Suppl 1):S59–S65. https://doi.org/10.1097/00126334-200309011-00009CrossRefPubMed

Sahanavin N, Prueksasit T, Tantrakarnapa K (2018) Relationship between PM10 and PM2.5 levels in high-traffic area determined using path analysis and linear regression [Article]. J Environ Sci 69:105–114. https://doi.org/10.1016/j.jes.2017.01.017CrossRef

Tian X, Chen J, Wang X, Xie Y, Zhang X, Han D, Fu H, Yin W, Wu N (2023) Global, regional, and national HIV/AIDS disease burden levels and trends in 1990-2019: A systematic analysis for the global burden of disease 2019 study [Article]. Frontiers. Public Health 11:1068664. https://doi.org/10.3389/fpubh.2023.1068664CrossRef

Tsui JI, Cheng DM, Libman H, Bridden C, Saitz R, Samet JH (2013) Risky alcohol use and serum aminotransferase levels in HIV-infected adults with and without hepatitis C. J Stud Alcohol Drugs 74(2):266–270. https://doi.org/10.15288/jsad.2013.74.266CrossRefPubMedPubMedCentral

UNAIDS (2017) National health and family planning commission of the Peoples Republic of China. 2015 China AIDS response progress report. https://www.unaids.org.cn/en/index/Documentview.asp?id=874. Accessed 22 Oct 2022

UNAIDS (2022) Global HIV & AIDS statistics - fact sheet. https://www.unaids.org/en/resources/fact-sheet. Accessed 25 Sept 2022

WHO (2017) Global hepatitis report 2017. https://www.who.int/publications/i/item/9789241565455. Accessed 18 Jun 2022

WHO (2022) Hepatitis C (2021). https://www.who.int/news-room/fact-sheets/detail/hepatitis-c. Accessed 7 Jun 2022

Xu C, Minghua S, Jianning J, Zhihong L, Qi W, Feifei W, Yi Z, Chunling T (2020) Epidemiological features of positive anti - HCV among the HIV - infected population in Guangxi, China. J Clin Hepatol 36(01):88–93. https://doi.org/10.3969/j.issn.1001-5256.2019.20.01.020CrossRef

Yan M, Wu B (2022) Hepatitis B and C mortality from 1990 to 2019 in China: a Bayesian age-period-cohort analysis [Article]. Annals Translational Med 10(24):1384. https://doi.org/10.21037/atm-22-5676CrossRef

Yang J, Qi J, Wang X, Li X, Jin R, Liu B, Liu H, Rao H (2023) The burden of hepatitis C virus in the world, China, India, and the United States from 1990 to 2019. Front Public Health 11:1041201. https://doi.org/10.3389/fpubh.2023.1041201CrossRefPubMedPubMedCentral

Zhao QG, Gong YH, Liao Q, Yu G, Wang K, Wang J, Yin BP, Yang SJ, Zhang JX, Liang PY, Wang QX (2016) Estimation on the HIV-1 incidence in Liangshan Yi Autonomous Prefecture, under BED-capture enzyme immunoassay, from 2011 to 2013. Zhonghua Liu Xing Bing Xue Za Zhi 37(8):1105–1107. https://doi.org/10.3760/cma.j.issn.0254-6450.2016.08.010CrossRefPubMed

Ziyan Z, Ling L (2021) Epidemiological Characteristics of Viral Hepatitis C in Liangshan From 2011 to 2020. J Prev Med Inform 37(07):924–928

Titel: Hepatitis C co-infection characteristics and correlates in newly reported HIV/AIDS patients in Southwest China, 2018–2022
verfasst von: Yulian Zhang
Chunnong Jike
Gang Yu
Ju Wang
Zhonghong Wang
Lazuo Ma
Tianlu Li
Yuan Li
Rong Pei
Publikationsdatum: 12.09.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Journal of Public Health
Print ISSN: 2198-1833
Elektronische ISSN: 1613-2238
DOI: https://doi.org/10.1007/s10389-023-02095-w

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Hepatitis C co-infection characteristics and correlates in newly reported HIV/AIDS patients in Southwest China, 2018–2022

Abstract

Aims

Subject and methods

Results

Conclusion

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Aims

Subject and methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten