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10.10.2022 | Review Article

Is low-level laser therapy effective in the treatment of herpes labialis? Systematic review and meta-analysis

verfasst von: Ana Waleska Pessoa Barros, Pedro Henrique da Hora Sales, Paulo Goberlânio de Barros Silva, Ana Claudia Amorim Gomes, Alessandra Albuquerque Tavares Carvalho, Jair Carneiro Leão

Erschienen in: Lasers in Medical Science | Ausgabe 9/2022

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Abstract

The objective of this systematic review is to evaluate the effectiveness of low-level laser therapy in the treatment of herpes labialis. The searches were carried out independently by 2 researchers and the articles were selected through the electronic databases according to the inclusion and exclusion criteria previously established. Initially, 480 articles were found, of which 7 randomized clinical trials and 1 clinical trial were selected. In total, 928 patients were included. In the meta-analysis, the mean healing time for laser use was significant, showing a mean reduction of 1.37 [CI 95% = 0.92 to 1.82] days for tissue healing (p < 0.0001). In the meta-analysis to evaluate the time for crust formation, there was no significant difference between the groups and no significant reduction in the mean time for crust formation (p = 0.150). Only one of the selected studies had a low risk of bias. The use of low-level laser proved to be effective in the treatment of herpes labialis. However, due to the high risk of bias in the included studies, there is a need to carry out new standardized studies to prove the effectiveness of this therapy.

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Titel: Is low-level laser therapy effective in the treatment of herpes labialis? Systematic review and meta-analysis
verfasst von: Ana Waleska Pessoa Barros
Pedro Henrique da Hora Sales
Paulo Goberlânio de Barros Silva
Ana Claudia Amorim Gomes
Alessandra Albuquerque Tavares Carvalho
Jair Carneiro Leão
Publikationsdatum: 10.10.2022
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 9/2022
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-022-03653-6

Springer Medizin

Abstract

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