Skip to main content
Erschienen in: Lasers in Medical Science 4/2014

01.07.2014 | Review Article

Laser treatment of recurrent herpes labialis: a literature review

verfasst von: Carlos de Paula Eduardo, Ana Cecilia Corrêa Aranha, Alyne Simões, Marina Stella Bello-Silva, Karen Muller Ramalho, Marcella Esteves-Oliveira, Patrícia Moreira de Freitas, Juliana Marotti, Jan Tunér

Erschienen in: Lasers in Medical Science | Ausgabe 4/2014

Einloggen, um Zugang zu erhalten

Abstract

Recurrent herpes labialis is a worldwide life-long oral health problem that remains unsolved. It affects approximately one third of the world population and causes frequent pain and discomfort episodes, as well as social restriction due to its compromise of esthetic features. In addition, the available antiviral drugs have not been successful in completely eliminating the virus and its recurrence. Currently, different kinds of laser treatment and different protocols have been proposed for the management of recurrent herpes labialis. Therefore, the aim of the present article was to review the literature regarding the effects of laser irradiation on recurrent herpes labialis and to identify the indications and most successful clinical protocols. The literature was searched with the aim of identifying the effects on healing time, pain relief, duration of viral shedding, viral inactivation, and interval of recurrence. According to the literature, none of the laser treatment modalities is able to completely eliminate the virus and its recurrence. However, laser phototherapy appears to strongly decrease pain and the interval of recurrences without causing any side effects. Photodynamic therapy can be helpful in reducing viral titer in the vesicle phase, and high-power lasers may be useful to drain vesicles. The main advantages of the laser treatment appear to be the absence of side effects and drug interactions, which are especially helpful for older and immunocompromised patients. Although these results indicate a potential beneficial use for lasers in the management of recurrent herpes labialis, they are based on limited published clinical trials and case reports. The literature still lacks double-blind controlled clinical trials verifying these effects and such trials should be the focus of future research.
Literatur
1.
Zurück zum Zitat Embil JA, Stephens RG, Manuel FR (1975) Prevalence of recurrent herpes labialis and aphthous ulcers among young adults on six continents. Can Med Assoc J 113(7):627–630PubMedCentralPubMed Embil JA, Stephens RG, Manuel FR (1975) Prevalence of recurrent herpes labialis and aphthous ulcers among young adults on six continents. Can Med Assoc J 113(7):627–630PubMedCentralPubMed
2.
Zurück zum Zitat Lowhagen GB, Bonde E, Eriksson B, Nordin P, Tunback P, Krantz I (2002) Self-reported herpes labialis in a Swedish population. Scand J Infect Dis 34(9):664–667PubMed Lowhagen GB, Bonde E, Eriksson B, Nordin P, Tunback P, Krantz I (2002) Self-reported herpes labialis in a Swedish population. Scand J Infect Dis 34(9):664–667PubMed
3.
Zurück zum Zitat Spruance SL (1992) The natural history of recurrent oral-facial herpes simplex virus infection. Semin Dermatol 11(3):200–206PubMed Spruance SL (1992) The natural history of recurrent oral-facial herpes simplex virus infection. Semin Dermatol 11(3):200–206PubMed
5.
Zurück zum Zitat Glenny AM, Fernandez Mauleffinch LM, Pavitt S, Walsh T (2009) Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer. Cochrane Database Syst Rev. doi:10.1002/14651858.CD006706.pub2 Glenny AM, Fernandez Mauleffinch LM, Pavitt S, Walsh T (2009) Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer. Cochrane Database Syst Rev. doi:10.​1002/​14651858.​CD006706.​pub2
6.
Zurück zum Zitat Harmenberg J, Oberg B, Spruance S (2010) Prevention of ulcerative lesions by episodic treatment of recurrent herpes labialis: a literature review. Acta Derm Venereol 90(2):122–130. doi:10.2340/00015555-0806 PubMed Harmenberg J, Oberg B, Spruance S (2010) Prevention of ulcerative lesions by episodic treatment of recurrent herpes labialis: a literature review. Acta Derm Venereol 90(2):122–130. doi:10.​2340/​00015555-0806 PubMed
8.
Zurück zum Zitat Opstelten W, Neven AK, Eekhof J (2008) Treatment and prevention of herpes labialis. Can Fam Physician 54(12):1683–1687PubMedCentralPubMed Opstelten W, Neven AK, Eekhof J (2008) Treatment and prevention of herpes labialis. Can Fam Physician 54(12):1683–1687PubMedCentralPubMed
9.
Zurück zum Zitat Miller CS, Danaher RJ, Jacob RJ (1998) Molecular aspects of herpes simplex virus I latency, reactivation, and recurrence. Crit Rev Oral Biol Med 9(4):541–562PubMed Miller CS, Danaher RJ, Jacob RJ (1998) Molecular aspects of herpes simplex virus I latency, reactivation, and recurrence. Crit Rev Oral Biol Med 9(4):541–562PubMed
10.
Zurück zum Zitat Arduino PG, Porter SR (2008) Herpes simplex virus type 1 infection: overview on relevant clinico-pathological features. J Oral Pathol Med 37(2):107–121PubMed Arduino PG, Porter SR (2008) Herpes simplex virus type 1 infection: overview on relevant clinico-pathological features. J Oral Pathol Med 37(2):107–121PubMed
12.
Zurück zum Zitat Axell T, Liedholm R (1990) Occurrence of recurrent herpes labialis in an adult Swedish population. Acta Odontol Scand 48(2):119–123PubMed Axell T, Liedholm R (1990) Occurrence of recurrent herpes labialis in an adult Swedish population. Acta Odontol Scand 48(2):119–123PubMed
13.
Zurück zum Zitat Reichart PA (2000) Oral mucosal lesions in a representative cross-sectional study of aging Germans. Community Dent Oral Epidemiol 28(5):390–398PubMed Reichart PA (2000) Oral mucosal lesions in a representative cross-sectional study of aging Germans. Community Dent Oral Epidemiol 28(5):390–398PubMed
15.
Zurück zum Zitat Esmann J (2001) The many challenges of facial herpes simplex virus infection. J Antimicrob Chemother 47(Suppl T1):17–27PubMed Esmann J (2001) The many challenges of facial herpes simplex virus infection. J Antimicrob Chemother 47(Suppl T1):17–27PubMed
16.
Zurück zum Zitat Arduino PG, Porter SR (2006) Oral and perioral herpes simplex virus type 1 (HSV-1) infection: review of its management. Oral Dis 12(3):254–270PubMed Arduino PG, Porter SR (2006) Oral and perioral herpes simplex virus type 1 (HSV-1) infection: review of its management. Oral Dis 12(3):254–270PubMed
17.
Zurück zum Zitat Fatahzadeh M, Schwartz RA (2007) Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J Am Acad Dermatol 57(5):737–763, quiz 764-736PubMed Fatahzadeh M, Schwartz RA (2007) Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J Am Acad Dermatol 57(5):737–763, quiz 764-736PubMed
18.
Zurück zum Zitat Raborn GW, Grace MG (2003) Recurrent herpes simplex labialis: selected therapeutic options. J Can Dent Assoc 69(8):498–503PubMed Raborn GW, Grace MG (2003) Recurrent herpes simplex labialis: selected therapeutic options. J Can Dent Assoc 69(8):498–503PubMed
19.
Zurück zum Zitat Spruance SL, Kriesel JD (2002) Treatment of herpes simplex labialis. Herpes 9(3):64–69PubMed Spruance SL, Kriesel JD (2002) Treatment of herpes simplex labialis. Herpes 9(3):64–69PubMed
20.
Zurück zum Zitat Fatahzadeh M, Schwartz RA (2007) Human herpes simplex labialis. Clin Exp Dermatol 32(6):625–630PubMed Fatahzadeh M, Schwartz RA (2007) Human herpes simplex labialis. Clin Exp Dermatol 32(6):625–630PubMed
21.
Zurück zum Zitat Spruance SL, Nett R, Marbury T, Wolff R, Johnson J, Spaulding T (2002) Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials. Antimicrob Agents Chemother 46(7):2238–2243PubMedCentralPubMed Spruance SL, Nett R, Marbury T, Wolff R, Johnson J, Spaulding T (2002) Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials. Antimicrob Agents Chemother 46(7):2238–2243PubMedCentralPubMed
22.
Zurück zum Zitat Birek C (2000) Herpesvirus-induced diseases: oral manifestations and current treatment options. J Calif Dent Assoc 28(12):911–921PubMed Birek C (2000) Herpesvirus-induced diseases: oral manifestations and current treatment options. J Calif Dent Assoc 28(12):911–921PubMed
23.
Zurück zum Zitat Su CT, Hsu JT, Hsieh HP, Lin PH, Chen TC, Kao CL, Lee CN, Chang SY (2008) Anti-HSV activity of digitoxin and its possible mechanisms. Antiviral Res 79(1):62–70PubMed Su CT, Hsu JT, Hsieh HP, Lin PH, Chen TC, Kao CL, Lee CN, Chang SY (2008) Anti-HSV activity of digitoxin and its possible mechanisms. Antiviral Res 79(1):62–70PubMed
24.
Zurück zum Zitat Baker D, Eisen D (2003) Valacyclovir for prevention of recurrent herpes labialis: 2 double-blind, placebo-controlled studies. Cutis 71(3):239–242PubMed Baker D, Eisen D (2003) Valacyclovir for prevention of recurrent herpes labialis: 2 double-blind, placebo-controlled studies. Cutis 71(3):239–242PubMed
25.
Zurück zum Zitat Diaz-Mitoma F, Sibbald RG, Shafran SD, Boon R, Saltzman RL (1998) Oral famciclovir for the suppression of recurrent genital herpes: a randomized controlled trial. Collaborative Famciclovir Genital Herpes Research Group. JAMA 280(10):887–892PubMed Diaz-Mitoma F, Sibbald RG, Shafran SD, Boon R, Saltzman RL (1998) Oral famciclovir for the suppression of recurrent genital herpes: a randomized controlled trial. Collaborative Famciclovir Genital Herpes Research Group. JAMA 280(10):887–892PubMed
26.
Zurück zum Zitat Kaplowitz LG, Baker D, Gelb L, Blythe J, Hale R, Frost P, Crumpacker C, Rabinovich S, Peacock JE Jr, Herndon J et al (1991) Prolonged continuous acyclovir treatment of normal adults with frequently recurring genital herpes simplex virus infection. The Acyclovir Study Group. JAMA 265(6):747–751PubMed Kaplowitz LG, Baker D, Gelb L, Blythe J, Hale R, Frost P, Crumpacker C, Rabinovich S, Peacock JE Jr, Herndon J et al (1991) Prolonged continuous acyclovir treatment of normal adults with frequently recurring genital herpes simplex virus infection. The Acyclovir Study Group. JAMA 265(6):747–751PubMed
28.
Zurück zum Zitat De Clercq E, Walker RT (1984) Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs. Pharmacol Ther 26(1):1–44PubMed De Clercq E, Walker RT (1984) Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs. Pharmacol Ther 26(1):1–44PubMed
29.
Zurück zum Zitat Shinkai I, Ohta Y (1996) New drugs—reports of new drugs recently approved by the FDA. Dirithromycin. Bioorg Med Chem 4(4):521–522PubMed Shinkai I, Ohta Y (1996) New drugs—reports of new drugs recently approved by the FDA. Dirithromycin. Bioorg Med Chem 4(4):521–522PubMed
30.
Zurück zum Zitat Bacon TH, Levin MJ, Leary JJ, Sarisky RT, Sutton D (2003) Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy. Clin Microbiol Rev 16(1):114–128PubMedCentralPubMed Bacon TH, Levin MJ, Leary JJ, Sarisky RT, Sutton D (2003) Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy. Clin Microbiol Rev 16(1):114–128PubMedCentralPubMed
31.
Zurück zum Zitat Datema R, Ericson AC, Field HJ, Larsson A, Stenberg K (1987) Critical determinants of antiherpes efficacy of buciclovir and related acyclic guanosine analogs. Antiviral Res 7(6):303–316PubMed Datema R, Ericson AC, Field HJ, Larsson A, Stenberg K (1987) Critical determinants of antiherpes efficacy of buciclovir and related acyclic guanosine analogs. Antiviral Res 7(6):303–316PubMed
32.
Zurück zum Zitat Earnshaw DL, Bacon TH, Darlison SJ, Edmonds K, Perkins RM, Vere Hodge RA (1992) Mode of antiviral action of penciclovir in MRC-5 cells infected with herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus. Antimicrob Agents Chemother 36(12):2747–2757PubMedCentralPubMed Earnshaw DL, Bacon TH, Darlison SJ, Edmonds K, Perkins RM, Vere Hodge RA (1992) Mode of antiviral action of penciclovir in MRC-5 cells infected with herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus. Antimicrob Agents Chemother 36(12):2747–2757PubMedCentralPubMed
33.
Zurück zum Zitat Morfin F, Thouvenot D (2003) Herpes simplex virus resistance to antiviral drugs. J Clin Virol 26(1):29–37PubMed Morfin F, Thouvenot D (2003) Herpes simplex virus resistance to antiviral drugs. J Clin Virol 26(1):29–37PubMed
34.
Zurück zum Zitat Huber MA (2003) Herpes simplex type-1 virus infection. Quintessence Int 34(6):453–467PubMed Huber MA (2003) Herpes simplex type-1 virus infection. Quintessence Int 34(6):453–467PubMed
35.
Zurück zum Zitat Karu TI (1986) Molecular mechanism of the therapeutic effect of low-intensity laser irradiation. Dokl Akad Nauk SSSR 291(5):1245–1249PubMed Karu TI (1986) Molecular mechanism of the therapeutic effect of low-intensity laser irradiation. Dokl Akad Nauk SSSR 291(5):1245–1249PubMed
36.
Zurück zum Zitat Lito P, Pantanowitz L, Marotti J, Aboulafia DM, Campbell V, Bower M, Dezube BJ (2009) Gastroenteropancreatic neuroendocrine tumors in patients with HIV infection: a trans-Atlantic series. Am J Med Sci 337(1):1–4. doi:10.1097/MAJ.0b013e31817d1cb7 PubMed Lito P, Pantanowitz L, Marotti J, Aboulafia DM, Campbell V, Bower M, Dezube BJ (2009) Gastroenteropancreatic neuroendocrine tumors in patients with HIV infection: a trans-Atlantic series. Am J Med Sci 337(1):1–4. doi:10.​1097/​MAJ.​0b013e31817d1cb7​ PubMed
37.
38.
Zurück zum Zitat Tunér J (2011) Laser phototherapy (LPT) in dentistry. Int CE Mag Laser Dent 1(8–17) Tunér J (2011) Laser phototherapy (LPT) in dentistry. Int CE Mag Laser Dent 1(8–17)
39.
Zurück zum Zitat Karu T (1989) Photobiology of low-power laser effects. Health Phys 56(5):691–704PubMed Karu T (1989) Photobiology of low-power laser effects. Health Phys 56(5):691–704PubMed
40.
Zurück zum Zitat Ramalho KM, Luiz AC, de Paula EC, Tunér J, Magalhaes RP, Gallottini Magalhaes M (2011) Use of laser phototherapy on a delayed wound healing of oral mucosa previously submitted to radiotherapy: case report. Int Wound J 8(4):413–418. doi:10.1111/j.1742-481X.2011.00788.x PubMed Ramalho KM, Luiz AC, de Paula EC, Tunér J, Magalhaes RP, Gallottini Magalhaes M (2011) Use of laser phototherapy on a delayed wound healing of oral mucosa previously submitted to radiotherapy: case report. Int Wound J 8(4):413–418. doi:10.​1111/​j.​1742-481X.​2011.​00788.​x PubMed
41.
Zurück zum Zitat Schindl A, Schindl M, Pernerstorfer-Schon H, Schindl L (2000) Low-intensity laser therapy: a review. J Investig Med 48(5):312–326PubMed Schindl A, Schindl M, Pernerstorfer-Schon H, Schindl L (2000) Low-intensity laser therapy: a review. J Investig Med 48(5):312–326PubMed
42.
Zurück zum Zitat Schaffer M, Bonel H, Sroka R, Schaffer PM, Busch M, Reiser M, Duhmke E (2000) Effects of 780 nm diode laser irradiation on blood microcirculation: preliminary findings on time-dependent T1-weighted contrast-enhanced magnetic resonance imaging (MRI). J Photochem Photobiol B 54(1):55–60PubMed Schaffer M, Bonel H, Sroka R, Schaffer PM, Busch M, Reiser M, Duhmke E (2000) Effects of 780 nm diode laser irradiation on blood microcirculation: preliminary findings on time-dependent T1-weighted contrast-enhanced magnetic resonance imaging (MRI). J Photochem Photobiol B 54(1):55–60PubMed
43.
Zurück zum Zitat Kudo HC, Inomata K, Okajima K, Moteji M, Oshiro T (1998) Low-level laser therapy: pain attenuation mechanisms. Laser Therapy 2:3–6 Kudo HC, Inomata K, Okajima K, Moteji M, Oshiro T (1998) Low-level laser therapy: pain attenuation mechanisms. Laser Therapy 2:3–6
44.
Zurück zum Zitat Hagiwara S, Iwasaka H, Okuda K, Noguchi T (2007) GaAlAs (830 nm) low-level laser enhances peripheral endogenous opioid analgesia in rats. Lasers Surg Med 39(10):797–802. doi:10.1002/lsm.20583 PubMed Hagiwara S, Iwasaka H, Okuda K, Noguchi T (2007) GaAlAs (830 nm) low-level laser enhances peripheral endogenous opioid analgesia in rats. Lasers Surg Med 39(10):797–802. doi:10.​1002/​lsm.​20583 PubMed
45.
Zurück zum Zitat Mizutani K, Musya Y, Wakae K, Kobayashi T, Tobe M, Taira K, Harada T (2004) A clinical study on serum prostaglandin E2 with low-level laser therapy. Photomed Laser Surg 22(6):537–539. doi:10.1089/pho.2004.22.537 PubMed Mizutani K, Musya Y, Wakae K, Kobayashi T, Tobe M, Taira K, Harada T (2004) A clinical study on serum prostaglandin E2 with low-level laser therapy. Photomed Laser Surg 22(6):537–539. doi:10.​1089/​pho.​2004.​22.​537 PubMed
46.
Zurück zum Zitat Chow RT, David MA, Armati PJ (2007) 830 nm laser irradiation induces varicosity formation, reduces mitochondrial membrane potential and blocks fast axonal flow in small and medium diameter rat dorsal root ganglion neurons: implications for the analgesic effects of 830 nm laser. J Peripher Nerv Syst 12(1):28–39. doi:10.1111/j.1529-8027.2007.00114.x PubMed Chow RT, David MA, Armati PJ (2007) 830 nm laser irradiation induces varicosity formation, reduces mitochondrial membrane potential and blocks fast axonal flow in small and medium diameter rat dorsal root ganglion neurons: implications for the analgesic effects of 830 nm laser. J Peripher Nerv Syst 12(1):28–39. doi:10.​1111/​j.​1529-8027.​2007.​00114.​x PubMed
47.
Zurück zum Zitat Donnarumma G, De Gregorio V, Fusco A, Farina E, Baroni A, Esposito V, Contaldo M, Petruzzi M, Pannone G, Serpico R (2010) Inhibition of HSV-1 replication by laser diode-irradiation: possible mechanism of action. Int J Immunopathol Pharmacol 23(4):1167–1176PubMed Donnarumma G, De Gregorio V, Fusco A, Farina E, Baroni A, Esposito V, Contaldo M, Petruzzi M, Pannone G, Serpico R (2010) Inhibition of HSV-1 replication by laser diode-irradiation: possible mechanism of action. Int J Immunopathol Pharmacol 23(4):1167–1176PubMed
48.
Zurück zum Zitat de Carvalho RR, de Paula EF, Ramalho KM, Antunes JL, Bezinelli LM, de Magalhaes MH, Pegoretti T, de Freitas PM, de Paula EC (2010) Effect of laser phototherapy on recurring herpes labialis prevention: an in vivo study. Lasers Med Sci 25(3):397–402. doi:10.1007/s10103-009-0717-9 PubMed de Carvalho RR, de Paula EF, Ramalho KM, Antunes JL, Bezinelli LM, de Magalhaes MH, Pegoretti T, de Freitas PM, de Paula EC (2010) Effect of laser phototherapy on recurring herpes labialis prevention: an in vivo study. Lasers Med Sci 25(3):397–402. doi:10.​1007/​s10103-009-0717-9 PubMed
49.
Zurück zum Zitat Sanchez PJM, Femenias JLC, Tejeda AD, Tunér J (2012) The of 670-nm low laser therapy on herpes simplex type 1. Photomed Laser Surg 30(1):37–40 Sanchez PJM, Femenias JLC, Tejeda AD, Tunér J (2012) The of 670-nm low laser therapy on herpes simplex type 1. Photomed Laser Surg 30(1):37–40
50.
Zurück zum Zitat Schindl A, Neumann R (1999) Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study. J Invest Dermatol 113(2):221–223. doi:10.1046/j.1523-1747.1999.00684.x PubMed Schindl A, Neumann R (1999) Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study. J Invest Dermatol 113(2):221–223. doi:10.​1046/​j.​1523-1747.​1999.​00684.​x PubMed
51.
Zurück zum Zitat Vélez-González M, Urrea-Arbeláez A, Nicolas M, Serra-Baldrich E, Perez JL, Pavesi M, Camarasa JMG, Trelles MA (1995) Treatment of relapse in herpes simplex on labial & facial areas and of primary herpes simplex on genital areas and “area pudenda” with low power laser (He-Ne) or Acyclovir administered orally. SPIE Proc 2630:43–50 Vélez-González M, Urrea-Arbeláez A, Nicolas M, Serra-Baldrich E, Perez JL, Pavesi M, Camarasa JMG, Trelles MA (1995) Treatment of relapse in herpes simplex on labial & facial areas and of primary herpes simplex on genital areas and “area pudenda” with low power laser (He-Ne) or Acyclovir administered orally. SPIE Proc 2630:43–50
52.
Zurück zum Zitat Eduardo CP, Bezinelli LM, Eduardo FP, Lopes RMG, Ramalho KM, Bello-Silva MS, Esteves-Oliveira M (2012) Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy. A clinical protocol with 3 years follow-up. Lasers Med Sci 27(5):1077–1083 Eduardo CP, Bezinelli LM, Eduardo FP, Lopes RMG, Ramalho KM, Bello-Silva MS, Esteves-Oliveira M (2012) Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy. A clinical protocol with 3 years follow-up. Lasers Med Sci 27(5):1077–1083
53.
Zurück zum Zitat Marotti J, Aranha AC, Eduardo Cde P, Ribeiro MS (2009) Photodynamic therapy can be effective as a treatment for herpes simplex labialis. Photomed Laser Surg 27(2):357–363. doi:10.1089/pho.2008.2268 PubMed Marotti J, Aranha AC, Eduardo Cde P, Ribeiro MS (2009) Photodynamic therapy can be effective as a treatment for herpes simplex labialis. Photomed Laser Surg 27(2):357–363. doi:10.​1089/​pho.​2008.​2268 PubMed
54.
Zurück zum Zitat Marotti J, Sperandio FF, Fregnani ER, Aranha AC, de Freitas PM, Eduardo Cde P (2010) High-intensity laser and photodynamic therapy as a treatment for recurrent herpes labialis. Photomed Laser Surg 28(3):439–444. doi:10.1089/pho.2009.2522 PubMed Marotti J, Sperandio FF, Fregnani ER, Aranha AC, de Freitas PM, Eduardo Cde P (2010) High-intensity laser and photodynamic therapy as a treatment for recurrent herpes labialis. Photomed Laser Surg 28(3):439–444. doi:10.​1089/​pho.​2009.​2522 PubMed
55.
Zurück zum Zitat Sperandio FF, Marotti J, Aranha AC, Eduardo Cde P (2009) Photodynamic therapy for the treatment of recurrent herpes labialis: preliminary results. Gen Dent 57(4):415–419PubMed Sperandio FF, Marotti J, Aranha AC, Eduardo Cde P (2009) Photodynamic therapy for the treatment of recurrent herpes labialis: preliminary results. Gen Dent 57(4):415–419PubMed
56.
Zurück zum Zitat Bello-Silva MS, de Freitas PM, Aranha AC, Lage-Marques JL, Simoes A, de Paula EC (2010) Low- and high-intensity lasers in the treatment of herpes simplex virus 1 infection. Photomed Laser Surg 28(1):135–139. doi:10.1089/pho.2008.2458 PubMed Bello-Silva MS, de Freitas PM, Aranha AC, Lage-Marques JL, Simoes A, de Paula EC (2010) Low- and high-intensity lasers in the treatment of herpes simplex virus 1 infection. Photomed Laser Surg 28(1):135–139. doi:10.​1089/​pho.​2008.​2458 PubMed
57.
Zurück zum Zitat Navarro R, Marquezan M, Cerqueira DF, Silveira BL, Correa MS (2007) Low-level-laser therapy as an alternative treatment for primary herpes simplex infection: a case report. J Clin Pediatr Dent 31(4):225–228PubMed Navarro R, Marquezan M, Cerqueira DF, Silveira BL, Correa MS (2007) Low-level-laser therapy as an alternative treatment for primary herpes simplex infection: a case report. J Clin Pediatr Dent 31(4):225–228PubMed
58.
Zurück zum Zitat de Paula EC, de Freitas PM, Esteves-Oliveira M, Aranha AC, Ramalho KM, Simoes A, Bello-Silva MS, Tuner J (2010) Laser phototherapy in the treatment of periodontal disease. A review Lasers Med Sci 25(6):781–792. doi:10.1007/s10103-010-0812-y de Paula EC, de Freitas PM, Esteves-Oliveira M, Aranha AC, Ramalho KM, Simoes A, Bello-Silva MS, Tuner J (2010) Laser phototherapy in the treatment of periodontal disease. A review Lasers Med Sci 25(6):781–792. doi:10.​1007/​s10103-010-0812-y
59.
Zurück zum Zitat Tunér J, Hode L (2007) The Laser Therapy Handbook. Prima Books, Grangesberg Tunér J, Hode L (2007) The Laser Therapy Handbook. Prima Books, Grangesberg
60.
Zurück zum Zitat Eduardo CP, Bezinelli LM, Eduardo FP, Lopes RMG, Ramalho KM, Bello-Silva MS, Esteves-Oliveira M (2012) Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy. A clinical protocol with 3 years follow-up. Las Med Sci 27(5):1077–1083 Eduardo CP, Bezinelli LM, Eduardo FP, Lopes RMG, Ramalho KM, Bello-Silva MS, Esteves-Oliveira M (2012) Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy. A clinical protocol with 3 years follow-up. Las Med Sci 27(5):1077–1083
61.
Zurück zum Zitat Gilioli G, Taparelli F, Fornaciari A, Palmieri B, Celani M (1985) Studio ultrastrutturale di colture cellulari “vero” infettate con virus Herpes Simplex e sottoposte all’- azione Laser [In Italian]. [Ultrastructural study of cell cultures infected with herpes simplex virus and subjected to the action of laser]. Med Laser Rep 3:28–31 Gilioli G, Taparelli F, Fornaciari A, Palmieri B, Celani M (1985) Studio ultrastrutturale di colture cellulari “vero” infettate con virus Herpes Simplex e sottoposte all’- azione Laser [In Italian]. [Ultrastructural study of cell cultures infected with herpes simplex virus and subjected to the action of laser]. Med Laser Rep 3:28–31
63.
Zurück zum Zitat Dougal G, Kelly P (2001) A pilot study of treatment of herpes labialis with 1072 nm narrow waveband light. Clin Exp Dermatol 26(2):149–154PubMed Dougal G, Kelly P (2001) A pilot study of treatment of herpes labialis with 1072 nm narrow waveband light. Clin Exp Dermatol 26(2):149–154PubMed
64.
Zurück zum Zitat Landthaler M, Haina D, Waidelich W (1983) Behandlung von zoster, postzosterischen schmerzen und herpes simplex recidivans in loco mit laser-licht. Fortsch Med 101:1039 Landthaler M, Haina D, Waidelich W (1983) Behandlung von zoster, postzosterischen schmerzen und herpes simplex recidivans in loco mit laser-licht. Fortsch Med 101:1039
65.
Zurück zum Zitat Ackermann G, Hartmann M, Scherer K, Lang EW, Hohenleutner U, Landthaler M, Baumler W (2002) Correlations between light penetration into skin and the therapeutic outcome following laser therapy of port-wine stains. Lasers Med Sci 17(2):70–78. doi:10.1007/s101030200013 PubMed Ackermann G, Hartmann M, Scherer K, Lang EW, Hohenleutner U, Landthaler M, Baumler W (2002) Correlations between light penetration into skin and the therapeutic outcome following laser therapy of port-wine stains. Lasers Med Sci 17(2):70–78. doi:10.​1007/​s101030200013 PubMed
66.
Zurück zum Zitat Tunér J, Hode L (1999) Low level laser therapy: clinical practice and scientific background. Prima Books, Grangesberg Tunér J, Hode L (1999) Low level laser therapy: clinical practice and scientific background. Prima Books, Grangesberg
67.
Zurück zum Zitat Niemz MH (1996) Laser-tissue interactions: fundamentals and applications, 1st edn. Springer, Berlin Niemz MH (1996) Laser-tissue interactions: fundamentals and applications, 1st edn. Springer, Berlin
68.
Zurück zum Zitat Azevedo LH, de Paula EF, Moreira MS, de Paula EC, Marques MM (2006) Influence of different power densities of LILT on cultured human fibroblast growth: a pilot study. Lasers Med Sci 21(2):86–89. doi:10.1007/s10103-006-0379-9 PubMed Azevedo LH, de Paula EF, Moreira MS, de Paula EC, Marques MM (2006) Influence of different power densities of LILT on cultured human fibroblast growth: a pilot study. Lasers Med Sci 21(2):86–89. doi:10.​1007/​s10103-006-0379-9 PubMed
69.
70.
Zurück zum Zitat Wainwright M (1998) Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother 42(1):13–28PubMed Wainwright M (1998) Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother 42(1):13–28PubMed
71.
Zurück zum Zitat Bhatti M, MacRobert A, Meghji S, Henderson B, Wilson M (1998) A study of the uptake of toluidine blue O by Porphyromonas gingivalis and the mechanism of lethal photosensitization. Photochem Photobiol 68(3):370–376PubMed Bhatti M, MacRobert A, Meghji S, Henderson B, Wilson M (1998) A study of the uptake of toluidine blue O by Porphyromonas gingivalis and the mechanism of lethal photosensitization. Photochem Photobiol 68(3):370–376PubMed
72.
Zurück zum Zitat Bhatti M, Nair SP, Macrobert AJ, Henderson B, Shepherd P, Cridland J, Wilson M (2001) Identification of photolabile outer membrane proteins of Porphyromonas gingivalis. Curr Microbiol 43(2):96–99. doi:10.1007/s002840010268 PubMed Bhatti M, Nair SP, Macrobert AJ, Henderson B, Shepherd P, Cridland J, Wilson M (2001) Identification of photolabile outer membrane proteins of Porphyromonas gingivalis. Curr Microbiol 43(2):96–99. doi:10.​1007/​s002840010268 PubMed
73.
Zurück zum Zitat Harris F, Chatfield LK, Phoenix DA (2005) Phenothiazinium based photosensitisers—photodynamic agents with a multiplicity of cellular targets and clinical applications. Curr Drug Targets 6(5):615–627PubMed Harris F, Chatfield LK, Phoenix DA (2005) Phenothiazinium based photosensitisers—photodynamic agents with a multiplicity of cellular targets and clinical applications. Curr Drug Targets 6(5):615–627PubMed
75.
Zurück zum Zitat Bandyopadhyay-Ghosh S, Reaney IM, Johnson A, Hurrell-Gillingham K, Brook IM, Hatton PV (2008) The effect of investment materials on the surface of cast fluorcanasite glasses and glass-ceramics. J Mater Sci Mater Med 19(2):839–846. doi:10.1007/s10856-007-3207-2 PubMed Bandyopadhyay-Ghosh S, Reaney IM, Johnson A, Hurrell-Gillingham K, Brook IM, Hatton PV (2008) The effect of investment materials on the surface of cast fluorcanasite glasses and glass-ceramics. J Mater Sci Mater Med 19(2):839–846. doi:10.​1007/​s10856-007-3207-2 PubMed
76.
Zurück zum Zitat Wainwright M (2003) Local treatment of viral disease using photodynamic therapy. Int J Antimicrob Agents 21(6):510–520PubMed Wainwright M (2003) Local treatment of viral disease using photodynamic therapy. Int J Antimicrob Agents 21(6):510–520PubMed
77.
Zurück zum Zitat Schulz EW (1928) Inactivation of Staphyloccus bacteriophage by Methylene Blue. Proc Soc Exp Biol Med 26:100–101 Schulz EW (1928) Inactivation of Staphyloccus bacteriophage by Methylene Blue. Proc Soc Exp Biol Med 26:100–101
78.
Zurück zum Zitat Felber TD, Smith EB, Knox JM, Wallis C, Melnick JL (1973) Photodynamic inactivation of herpes simplex. J Am Med Assoc 223(3):289–292 Felber TD, Smith EB, Knox JM, Wallis C, Melnick JL (1973) Photodynamic inactivation of herpes simplex. J Am Med Assoc 223(3):289–292
79.
Zurück zum Zitat Rapp F, Kemeny BA (1977) Oncogenic potential of herpes simplex virus in mammalian cells following photodynamic inactivation. Photochem Photobiol 25(4):335–337PubMed Rapp F, Kemeny BA (1977) Oncogenic potential of herpes simplex virus in mammalian cells following photodynamic inactivation. Photochem Photobiol 25(4):335–337PubMed
80.
81.
Zurück zum Zitat Owens JW, Robins M (2000) The role of second generation organometallic complexes in the photodynamic therapeutic treatment of cancer. Recent Res Dev Inorg Chem 2:41–55 Owens JW, Robins M (2000) The role of second generation organometallic complexes in the photodynamic therapeutic treatment of cancer. Recent Res Dev Inorg Chem 2:41–55
82.
Zurück zum Zitat Ackroyd R, Brown N, Vernon D, Roberts D, Stephenson T, Marcus S, Stoddard C, Reed M (1999) 5-Aminolevulinic acid photosensitization of dysplastic Barrett’s esophagus: a pharmacokinetic study. Photochem Photobiol 70(4):656–662PubMed Ackroyd R, Brown N, Vernon D, Roberts D, Stephenson T, Marcus S, Stoddard C, Reed M (1999) 5-Aminolevulinic acid photosensitization of dysplastic Barrett’s esophagus: a pharmacokinetic study. Photochem Photobiol 70(4):656–662PubMed
83.
Zurück zum Zitat Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ (1996) The risk of transfusion-transmitted viral infections. The retrovirus epidemiology donor study. N Engl J Med 334(26):1685–1690. doi:10.1056/NEJM199606273342601 PubMed Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ (1996) The risk of transfusion-transmitted viral infections. The retrovirus epidemiology donor study. N Engl J Med 334(26):1685–1690. doi:10.​1056/​NEJM199606273342​601 PubMed
86.
Zurück zum Zitat Wagner SJ, Skripchenko A, Robinette D, Foley JW, Cincotta L (1998) Factors affecting virus photoinactivation by a series of phenothiazine dyes. Photochem Photobiol 67(3):343–349PubMed Wagner SJ, Skripchenko A, Robinette D, Foley JW, Cincotta L (1998) Factors affecting virus photoinactivation by a series of phenothiazine dyes. Photochem Photobiol 67(3):343–349PubMed
87.
Zurück zum Zitat Schnipper LE, Lewin AA, Swartz M, Crumpacker CS (1980) Mechanisms of photodynamic inactivation of herpes simplex viruses: comparison between methylene blue, light plus electricity, and hematoporhyrin plus light. J Clin Invest 65(2):432–438. doi:10.1172/JCI109686 PubMedCentralPubMed Schnipper LE, Lewin AA, Swartz M, Crumpacker CS (1980) Mechanisms of photodynamic inactivation of herpes simplex viruses: comparison between methylene blue, light plus electricity, and hematoporhyrin plus light. J Clin Invest 65(2):432–438. doi:10.​1172/​JCI109686 PubMedCentralPubMed
88.
Zurück zum Zitat Lambrecht B, Mohr H, Knuver-Hopf J, Schmitt H (1991) Photoinactivation of viruses in human fresh plasma by phenothiazine dyes in combination with visible light. Vox Sang 60(4):207–213PubMed Lambrecht B, Mohr H, Knuver-Hopf J, Schmitt H (1991) Photoinactivation of viruses in human fresh plasma by phenothiazine dyes in combination with visible light. Vox Sang 60(4):207–213PubMed
89.
Zurück zum Zitat Tuite EM, Kelly JM (1993) Photochemical interactions of methylene blue and analogues with DNA and other biological substrates. J Photochem Photobiol B 21(2–3):103–124PubMed Tuite EM, Kelly JM (1993) Photochemical interactions of methylene blue and analogues with DNA and other biological substrates. J Photochem Photobiol B 21(2–3):103–124PubMed
90.
Zurück zum Zitat Muller-Breitkreutz K, Mohr H (1997) Infection cycle of herpes viruses after photodynamic treatment with methylene blue and light. Beitr Infusionsther Transfusionsmed 34:37–42PubMed Muller-Breitkreutz K, Mohr H (1997) Infection cycle of herpes viruses after photodynamic treatment with methylene blue and light. Beitr Infusionsther Transfusionsmed 34:37–42PubMed
91.
Zurück zum Zitat Muller-Breitkreutz K, Mohr H, Briviba K, Sies H (1995) Inactivation of viruses by chemically and photochemically generated singlet molecular oxygen. J Photochem Photobiol B 30(1):63–70PubMed Muller-Breitkreutz K, Mohr H, Briviba K, Sies H (1995) Inactivation of viruses by chemically and photochemically generated singlet molecular oxygen. J Photochem Photobiol B 30(1):63–70PubMed
92.
Zurück zum Zitat Wainwright M (2002) The emerging chemistry of blood product disinfection. Chem Soc Rev 31(2):128–136PubMed Wainwright M (2002) The emerging chemistry of blood product disinfection. Chem Soc Rev 31(2):128–136PubMed
93.
Zurück zum Zitat Wagner SJ, Skripchenko A, Robinette D, Mallory DA, Cincotta L (1998) Preservation of red cell properties after virucidal phototreatment with dimethylmethylene blue. Transfusion 38(8):729–737PubMed Wagner SJ, Skripchenko A, Robinette D, Mallory DA, Cincotta L (1998) Preservation of red cell properties after virucidal phototreatment with dimethylmethylene blue. Transfusion 38(8):729–737PubMed
94.
Zurück zum Zitat Wainwright M, Phoenix DA, Rice L, Burrow SM, Waring J (1997) Increased cytotoxicity and phototoxicity in the methylene blue series via chromophore methylation. J Photochem Photobiol B 40(3):233–239PubMed Wainwright M, Phoenix DA, Rice L, Burrow SM, Waring J (1997) Increased cytotoxicity and phototoxicity in the methylene blue series via chromophore methylation. J Photochem Photobiol B 40(3):233–239PubMed
95.
Zurück zum Zitat Ben-Hur E, Hoeben RC, Van Ormondt H, Dubbelman TM, Van Steveninck J (1992) Photodynamic inactivation of retroviruses by phthalocyanines: the effects of sulphonation, metal ligand and fluoride. J Photochem Photobiol B 13(2):145–152PubMed Ben-Hur E, Hoeben RC, Van Ormondt H, Dubbelman TM, Van Steveninck J (1992) Photodynamic inactivation of retroviruses by phthalocyanines: the effects of sulphonation, metal ligand and fluoride. J Photochem Photobiol B 13(2):145–152PubMed
96.
Zurück zum Zitat Van Lier JE (1990) Phthalocyanines as sensitizers for PDT of cancer. In: Kessel D (ed) Photodynamic therapy of neoplasis diseases, vol 1. CRC Press, Boca Raton, pp 279–291 Van Lier JE (1990) Phthalocyanines as sensitizers for PDT of cancer. In: Kessel D (ed) Photodynamic therapy of neoplasis diseases, vol 1. CRC Press, Boca Raton, pp 279–291
97.
Zurück zum Zitat Smetana Z, Mendelson E, Manor J, van Lier JE, Ben-Hur E, Salzberg S, Malik Z (1994) Photodynamic inactivation of herpes viruses with phthalocyanine derivatives. J Photochem Photobiol B 22(1):37–43PubMed Smetana Z, Mendelson E, Manor J, van Lier JE, Ben-Hur E, Salzberg S, Malik Z (1994) Photodynamic inactivation of herpes viruses with phthalocyanine derivatives. J Photochem Photobiol B 22(1):37–43PubMed
98.
Zurück zum Zitat Smetana Z, Ben-Hur E, Mendelson E, Salzberg S, Wagner P, Malik Z (1998) Herpes simplex virus proteins are damaged following photodynamic inactivation with phthalocyanines. J Photochem Photobiol B 44(1):77–83. doi:10.1016/S1011-1344(98)00124-9 PubMed Smetana Z, Ben-Hur E, Mendelson E, Salzberg S, Wagner P, Malik Z (1998) Herpes simplex virus proteins are damaged following photodynamic inactivation with phthalocyanines. J Photochem Photobiol B 44(1):77–83. doi:10.​1016/​S1011-1344(98)00124-9 PubMed
99.
Zurück zum Zitat Rywkin S, Lenny L, Goldstein J, Geacintov NE, Margolis-Nunno H, Horowitz B (1992) Importance of type I and type II mechanisms in the photodynamic inactivation of viruses in blood with aluminum phthalocyanine derivatives. Photochem Photobiol 56(4):463–469PubMed Rywkin S, Lenny L, Goldstein J, Geacintov NE, Margolis-Nunno H, Horowitz B (1992) Importance of type I and type II mechanisms in the photodynamic inactivation of viruses in blood with aluminum phthalocyanine derivatives. Photochem Photobiol 56(4):463–469PubMed
100.
Zurück zum Zitat Javaly K, Wohlfeiler M, Kalayjian R, Klein T, Bryson Y, Grafford K, Martin-Munley S, Hardy WD (1999) Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study. J Acquir Immune Defic Syndr 21(4):301–306PubMed Javaly K, Wohlfeiler M, Kalayjian R, Klein T, Bryson Y, Grafford K, Martin-Munley S, Hardy WD (1999) Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study. J Acquir Immune Defic Syndr 21(4):301–306PubMed
101.
Zurück zum Zitat Lytle CD, Carney PG, Felten RP, Bushar HF, Straight RC (1989) Inactivation and mutagenesis of herpes virus by photodynamic treatment with therapeutic dyes. Photochem Photobiol 50(3):367–371PubMed Lytle CD, Carney PG, Felten RP, Bushar HF, Straight RC (1989) Inactivation and mutagenesis of herpes virus by photodynamic treatment with therapeutic dyes. Photochem Photobiol 50(3):367–371PubMed
102.
Zurück zum Zitat Ackroyd R, Kelty C, Brown N, Reed M (2001) The history of photodetection and photodynamic therapy. Photochem Photobiol 74(5):656–669PubMed Ackroyd R, Kelty C, Brown N, Reed M (2001) The history of photodetection and photodynamic therapy. Photochem Photobiol 74(5):656–669PubMed
103.
Zurück zum Zitat Kvacheva ZB, Shukanova NA, Votyakov VI, Lobanok ES, Vorobei AV, Nikolaeva SN (2003) Photodynamic inhibition of infection caused by drug-resistant variants of herpes simplex virus type I. Bull Exp Biol Med 135(4):384–387PubMed Kvacheva ZB, Shukanova NA, Votyakov VI, Lobanok ES, Vorobei AV, Nikolaeva SN (2003) Photodynamic inhibition of infection caused by drug-resistant variants of herpes simplex virus type I. Bull Exp Biol Med 135(4):384–387PubMed
104.
Zurück zum Zitat Hsi RA, Rosenthal DI, Glatstein E (1999) Photodynamic therapy in the treatment of cancer: current state of the art. Drugs 57(5):725–734PubMed Hsi RA, Rosenthal DI, Glatstein E (1999) Photodynamic therapy in the treatment of cancer: current state of the art. Drugs 57(5):725–734PubMed
105.
106.
Zurück zum Zitat Englund JA, Zimmerman ME, Swierkosz EM, Goodman JL, Scholl DR, Balfour HH Jr (1990) Herpes simplex virus resistant to acyclovir. A study in a tertiary care center. Ann Intern Med 112(6):416–422PubMed Englund JA, Zimmerman ME, Swierkosz EM, Goodman JL, Scholl DR, Balfour HH Jr (1990) Herpes simplex virus resistant to acyclovir. A study in a tertiary care center. Ann Intern Med 112(6):416–422PubMed
107.
Zurück zum Zitat Komerik N, Curnow A, MacRobert AJ, Hopper C, Speight PM, Wilson M (2002) Fluorescence biodistribution and photosensitising activity of toluidine blue o on rat buccal mucosa. Lasers Med Sci 17(2):86–92. doi:10.1007/s101030200015 PubMed Komerik N, Curnow A, MacRobert AJ, Hopper C, Speight PM, Wilson M (2002) Fluorescence biodistribution and photosensitising activity of toluidine blue o on rat buccal mucosa. Lasers Med Sci 17(2):86–92. doi:10.​1007/​s101030200015 PubMed
108.
Zurück zum Zitat Eduardo CP (2010) Laser in contemporary clinical dentistry. In: Fernandes CP (ed) A world class dentistry, FDI 2010. Livraria Santos, Brazil, pp 237–264 Eduardo CP (2010) Laser in contemporary clinical dentistry. In: Fernandes CP (ed) A world class dentistry, FDI 2010. Livraria Santos, Brazil, pp 237–264
109.
Zurück zum Zitat Ohshiro T, Fujino T (1993) Laser applications in plastic and reconstructive surgery. Keio J Med 42(4):191–195PubMed Ohshiro T, Fujino T (1993) Laser applications in plastic and reconstructive surgery. Keio J Med 42(4):191–195PubMed
110.
Zurück zum Zitat Meister J (2007) Basic research. In: Gutknecht N (ed) Proceedings of the 1st International Workshop of Evidence Based Dentistry on Lasers in Dentistry. Quintessence, Berlin, pp 3–27 Meister J (2007) Basic research. In: Gutknecht N (ed) Proceedings of the 1st International Workshop of Evidence Based Dentistry on Lasers in Dentistry. Quintessence, Berlin, pp 3–27
111.
Zurück zum Zitat Calderhead RG (1991) Simultaneous LLLT in laser surgery: the phenomenon explained. In: Ohshiro T, Calderhead RG (eds) Progress in laser therapy. Wiley, Chichester, pp 209–213 Calderhead RG (1991) Simultaneous LLLT in laser surgery: the phenomenon explained. In: Ohshiro T, Calderhead RG (eds) Progress in laser therapy. Wiley, Chichester, pp 209–213
112.
Zurück zum Zitat Kaufmann R, Hibst R (1990) Pulsed 2.94-microns erbium-YAG laser skin ablation—experimental results and first clinical application. Clin Exp Dermatol 15(5):389–393PubMed Kaufmann R, Hibst R (1990) Pulsed 2.94-microns erbium-YAG laser skin ablation—experimental results and first clinical application. Clin Exp Dermatol 15(5):389–393PubMed
114.
Zurück zum Zitat Hughes PS, Hughes AP (1998) Absence of human papillomavirus DNA in the plume of erbium:YAG laser-treated warts. J Am Acad Dermatol 38(3):426–428PubMed Hughes PS, Hughes AP (1998) Absence of human papillomavirus DNA in the plume of erbium:YAG laser-treated warts. J Am Acad Dermatol 38(3):426–428PubMed
115.
Zurück zum Zitat Trevor M (1987) Presence of virus in CO2 laser plumes raises infection concern. Hospital Infection Control 14:166–167 Trevor M (1987) Presence of virus in CO2 laser plumes raises infection concern. Hospital Infection Control 14:166–167
116.
Zurück zum Zitat Kotlow L (2011) Lasers in pediatric dentistry. In: Convissar RA (ed) Principles and practice of laser dentistry. Mosby, Elsevier, St. Louis, pp 202–224 Kotlow L (2011) Lasers in pediatric dentistry. In: Convissar RA (ed) Principles and practice of laser dentistry. Mosby, Elsevier, St. Louis, pp 202–224
117.
Zurück zum Zitat Tunér J, Beck-Kristensen PH (2011) Low-level lasers in dentistry. In: Convissar RA (ed) Principles and practice of laser dentistry. Mosby, Elsevier, St. Louis, pp 263–286 Tunér J, Beck-Kristensen PH (2011) Low-level lasers in dentistry. In: Convissar RA (ed) Principles and practice of laser dentistry. Mosby, Elsevier, St. Louis, pp 263–286
Metadaten
Titel
Laser treatment of recurrent herpes labialis: a literature review
verfasst von
Carlos de Paula Eduardo
Ana Cecilia Corrêa Aranha
Alyne Simões
Marina Stella Bello-Silva
Karen Muller Ramalho
Marcella Esteves-Oliveira
Patrícia Moreira de Freitas
Juliana Marotti
Jan Tunér
Publikationsdatum
01.07.2014
Verlag
Springer London
Erschienen in
Lasers in Medical Science / Ausgabe 4/2014
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-013-1311-8

Weitere Artikel der Ausgabe 4/2014

Lasers in Medical Science 4/2014 Zur Ausgabe