Gastric Cancer OnlineFirst articles

14.05.2024 | Original Article

Molecular features and prognostic factors of locally advanced microsatellite instability-high gastric cancer

Gastric cancer is the sixth most common cancer and the fifth leading cause of cancer-related death worldwide [ 1 ]. Gastrectomy with D2 lymph node dissection and perioperative chemotherapy have been reported to improve survival in patients with …

verfasst von:: Kenichiro Furukawa, Keiichi Hatakeyama, Masanori Terashima, Kenichi Urakami, Yusuke Koseki, Keiichi Fujiya, Yutaka Tanizawa, Etsuro Bando, Ken Yamaguchi

Open Access 09.05.2024 | Original Article

Claudin-18 status and its correlation with HER2 and PD-L1 expression in gastric cancer with peritoneal dissemination

Gastric cancer is the fourth leading cause of cancer-related deaths worldwide [ 1 ]. The morbidity and mortality rates are declining because of the decreasing prevalence of Helicobacter pylori infection, widespread H.pylori eradication therapy, and …

verfasst von:: Haruki Ogawa, Hiroyuki Abe, Koichi Yagi, Yasuyuki Seto, Tetsuo Ushiku

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Open Access 30.04.2024 | Original Article

Adjuvant and post-recurrent treatment patterns in patients with resectable gastric cancer in japan: a retrospective database cohort study

Gastric cancer (GC) is the third most common cause of cancer-related death in Japan, with approximately 41,100 GC-related deaths in 2022 [ 1 ]. In patients with advanced resectable GC, surgical resection with adequate lymphadenopathy and adjuvant …

verfasst von:: Takaki Yoshikawa, Yorifumi Kikko, Reina Makino, Yuya Kimijima, Eiji Nishiyama, Yuko Matsuda, Bruno Casaes Teixeira, Mariella Tejada, Robert Carroll, Shuichi Hironaka

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Open Access 26.04.2024 | Original Article

Revisiting the use of the EORTC QLQ-STO22 to assess health-related quality of life of patients with gastric cancer: incorporating updated treatment options and cross-cultural perspectives

According to the GLOBOCAN 2020 database, gastric cancer (GC) is ranked among the top three most common cancers in 19 countries, with an estimated 1.1 million cases and 770,000 deaths annually [ 1 ]. Countries within East Asia (Japan, South Korea …

verfasst von:: S. C. Sodergren, A. Hurley-Wallace, V. Vassiliou, B. Alkhaffaf, B. Batsaikhan, A. S. Darlington, T. Fleitas-Kanonnikof, M. G. Guren, M. Honda, Y. W. Kim, S. Kim, M. N. Krishnamurthy, S. Y. Loh, N. S. Turhal, J. Zhou, K. Dennis, R. Krishnatry, M. Terashima, G. Tsironis, T. Yoshikawa, M. Terada, On behalf of the EORTC Quality of Life Group

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25.04.2024 | Original Article

Identification of maximal tumor size associated with negligible lymph node metastasis for endoscopic submucosal dissection of undifferentiated-type early gastric cancer

Gastric cancer is a global health problem and is the fifth most common cancer and third most common cause of cancer-specific mortality worldwide [ 1 ]. There are notable differences in the epidemiology of gastric cancer between East Asian and …

verfasst von:: Sung Eun Oh, Soomin Ahn, Kyoung-Mee Kim, Min-Gew Choi, Jun Ho Lee, Tae Sung Sohn, Jae Moon Bae, Ji Yeong An

22.04.2024 | Original Article

Feasibility of intraoperative pathologic examination for sentinel lymph nodes during sentinel node navigation surgery in early gastric cancer: results of pathologic protocol for SENORITA trial

Both the incidence and survival rate of early gastric cancer (EGC) have been increasing in Korea [ 1 , 2 ], and so have the efforts to reduce the need for radical surgery. Lymph node metastasis occurs in only 10–16% of patients with EGC [ 3 – 6 ].

verfasst von:: Sin Hye Park, Soo Young Chung, Jeong-Hee Lee, Hee Kyung Kim, Dakeun Lee, Hyunki Kim, Jo-Heon Kim, Min Seok Kim, Jae Hyuk Lee, Ji Yeon Park, Hong Man Yoon, Keun Won Ryu, Myeong-Cherl Kook

Open Access 22.04.2024 | Original Article

Family history and gastric cancer incidence and mortality in Asia: a pooled analysis of more than half a million participants

Despite the incidence and mortality of gastric cancer having declined globally in the past decades, gastric cancer remains one of the most common cancers worldwide with more than one million new cases and nearly 800,000 deaths every year [ 1 ]. The …

verfasst von:: Dan Huang, Minkyo Song, Sarah Krull Abe, Md. Shafiur Rahman, Md. Rashedul Islam, Eiko Saito, Katherine De la Torre, Norie Sawada, Akiko Tamakoshi, Xiao-Ou Shu, Hui Cai, Atsushi Hozawa, Seiki Kanemura, Jeongseon Kim, Yu Chen, Hidemi Ito, Yumi Sugawara, Sue K. Park, Myung-Hee Shin, Mayo Hirabayashi, Takashi Kimura, Yu-Tang Gao, Wanqing Wen, Isao Oze, Aesun Shin, Yoon-Ok Ahn, Habibul Ahsan, Paolo Boffetta, Kee Seng Chia, Keitaro Matsuo, You-Lin Qiao, Nathaniel Rothman, Wei Zheng, Manami Inoue, Daehee Kang

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22.04.2024 | Original Article

Discordant PD-L1 results between 28–8 and 22C3 assays are associated with outcomes of gastric cancer patients treated with nivolumab plus chemotherapy

Gastric cancer is the fourth leading cause of cancer-related mortality and the fifth most common malignancy worldwide [ 1 ]. The past decade has seen substantial advances in systemic chemotherapy for patients with advanced gastric cancer …

verfasst von:: Hyung-Don Kim, Jinho Shin, In Hye Song, Jaewon Hyung, Hyungeun Lee, Min-Hee Ryu, Young Soo Park

Open Access 18.04.2024 | Original Article

International consensus on the management of metastatic gastric cancer: step by step in the foggy landscape

Bertinoro Workshop, November 2022

Gastric cancer is still one of the leading causes of cancer-related deaths worldwide, with over one million of new cases in 2020 and an estimated 769,000 deaths, ranking fifth for incidence and fourth for mortality globally [ 1 ].

verfasst von:: Paolo Morgagni, Maria Bencivenga, Fatima Carneiro, Stefano Cascinu, Sarah Derks, Maria Di Bartolomeo, Claire Donohoe, Clarisse Eveno, Suzanne Gisbertz, Peter Grimminger, Ines Gockel, Heike Grabsh, Paulo Kassab, Rupert Langer, Sara Lonardi, Marco Maltoni, Sheraz Markar, Markus Moehler, Daniele Marrelli, Maria Antonietta Mazzei, Davide Melisi, Carlo Milandri, Paul Stefan Moenig, Bianca Mostert, Gianni Mura, Wojciech Polkowski, John Reynolds, Luca Saragoni, Mark I. Van Berge Henegouwen, Richard Van Hillegersberg, Michael Vieth, Giuseppe Verlato, Lorena Torroni, Bas Wijnhoven, Guido Alberto Massimo Tiberio, Han-Kwang Yang, Franco Roviello, Giovanni de Manzoni

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Open Access 17.04.2024 | Original Article

Adding salt to food at table as an indicator of gastric cancer risk among adults: a prospective study

Gastric cancer is the fifth most commonly diagnosed cancer globally [ 1 ], with the highest prevalence in Asia, followed by Eastern Europe and Latin Americas [ 1 – 3 ]. Gastric cancer risk increases with age and is more prevalent in males, while …

verfasst von:: Selma Kronsteiner-Gicevic, Alysha S. Thompson, Martina Gaggl, William Bell, Aedín Cassidy, Tilman Kühn

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11.04.2024 | Letter to the Editor

Letter to the editor: 5-year follow-up results of a JCOG1104 (OPAS-1) phase III non-inferiority trial to compare 4 courses and 8 courses of S-1 adjuvant chemotherapy for pathological stage II gastric cancer

verfasst von:: Hyung-Don Kim, Min-Hee Ryu, Ji Sung Lee, Yoon-Koo Kang

07.04.2024 | Original Article

Genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA as noninvasive diagnostic markers for gastric cancer

Gastric cancer (GC) is the fifth most diagnosed malignancy worldwide, with over 1 million estimated new cases annually [ 1 ], and it is the third leading cause of global cancer mortality [ 2 ], with an average 5-year survival rate of only …

verfasst von:: Yingli Fu, Jing Jiang, Yanhua Wu, Donghui Cao, Zhifang Jia, Yangyu Zhang, Dongming Li, Yingnan Cui, Yuzheng Zhang, Xueyuan Cao

04.04.2024 | Original Article

Precise highlighting of the pancreas by semantic segmentation during robot-assisted gastrectomy: visual assistance with artificial intelligence for surgeons

The infrapyloric and suprapancreatic lymph nodes, categorized as stations 6, 8a, 11p, and 11d by the Japanese gastric cancer association [ 1 ], should be dissected during radical gastrectomy for gastric cancer [ 2 ]. During lymphadenectomy around …

verfasst von:: Tatsuro Nakamura, Nao Kobayashi, Yuta Kumazu, Kyohei Fukata, Motoki Murakami, Shugo Kohno, Yudai Hojo, Eiichiro Nakao, Yasunori Kurahashi, Yoshinori Ishida, Hisashi Shinohara

Open Access 03.04.2024 | Original Article

Global burden of young-onset gastric cancer: a systematic trend analysis of the global burden of disease study 2019

Gastric cancer is a prevalent cancer worldwide, accounting for 5.6% of all new cancer cases (ranking fifth in incidence) and 7.7% of all cancer deaths (ranking fourth in mortality) in 2020 [ 1 ]. Gastric cancer is more often diagnosed in …

verfasst von:: Yunhao Li, Anne I. Hahn, Monika Laszkowska, Fang Jiang, Ann G. Zauber, Wai K. Leung

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01.04.2024 | Original Article

Risk prediction model for gastric cancer within 5 years in healthy Korean adults

Gastric cancer is the sixth most common cancer in 2020, with 1.09 million cases worldwide [ 1 ]. East Asian countries, including South Korea, have recorded high incidence rates of gastric cancer [ 2 , 3 ]. Although the recent incidence of gastric …

verfasst von:: Hyungseok Oh, Sunwoo Cho, Jung Ah Lee, Seungho Ryu, Yoosoo Chang

31.03.2024 | Original Article

Prognostic value of mismatch repair deficiency in patients receiving first-line fluoropyrimidine plus platinum for metastatic, recurrent, or unresectable gastric cancer

Globally, gastric cancer (GC) is the fourth leading cause of cancer related mortality and the fifth most commonly diagnosed cancer, responsible for over one million new cases in 2020 [ 1 ]. Although curative surgery is performed at localized stage …

verfasst von:: Chung Ryul Oh, Eo Jin Kim, Heejung Chae, Young Soo Park, Min-Hee Ryu, Hyung-Don Kim, Yoon-Koo Kang

Open Access 03.11.2019 | Correction

Correction to: Developing real-world comparators for clinical trials in chemotherapy-refractory patients with gastric cancer or gastroesophageal junction cancer

ping real-world comparators for …

verfasst von:: Ian Chau, Dung T. Le, Patrick A. Ott, Beata Korytowsky, Hannah Le, T. Kim Le, Ying Zhang, Teresa Sanchez, Gregory A. Maglinte, Melissa Laurie, Pranav Abraham, Dhiren Patel, Tong Shangguan

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