This study aims to investigate the altered patterns of dynamic functional network connectivity (dFNC) between deficit schizophrenia (DS) and non-deficit schizophrenia (NDS), and further explore the associations with cognitive impairments. 70 DS …
Ketamine has demonstrated rapid and sustained antidepressant effects, marking its emergence as an innovative treatment of depression. Despite the growing number of preclinical and clinical studies exploring the antidepressant effects of ketamine …
verfasst von:
Li-yuan Zhao, Guang-fen Zhang, Xue-jie Lou, Kenji Hashimoto, Jian-jun Yang
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition with onset in childhood and a high rate of persistence into adulthood [ 1 ]. ADHD is associated with co-occurring mental [ 1 ] and somatic conditions [ 2 ] …
verfasst von:
Jutta S. Mayer, Laura Kohlhas, Jacek Stermann, Juliane Medda, Geva A. Brandt, Oliver Grimm, Adam D. Pawley, Philip Asherson, Judit Palacio Sanchez, Vanesa Richarte, Douwe Bergsma, Elena D. Koch, Adrià Muntaner-Mas, Ulrich W. Ebner-Priemer, Meinhard Kieser, Wolfgang Retz, Francisco B. Ortega, Michael Colla, Jan K. Buitelaar, Jonna Kuntsi, Josep A. Ramos-Quiroga, Andreas Reif, Christine M. Freitag
Criminal behavior is known to peak in people in their 20s and to decline later in life [ 1 ]. However, arrest rates in older age groups are increasing [ 1 ], and the number and proportion of older prisoners have escalated globally over the past …
verfasst von:
Anniina Palm, Tiina Talaslahti, Risto Vataja, Milena Ginters, Hannu Kautiainen, Henrik Elonheimo, Jaana Suvisaari, Nina Lindberg, Hannu Koponen
Nitrous oxide (N2O) has been known since the end of the eighteenth century. Today, N2O plays a huge role as a greenhouse gas and an ozone-depleting stratospheric molecule. The main sources of anthropogenic N2O emissions are agriculture, fuel …
verfasst von:
Golo Kronenberg, Georgios Schoretsanitis, Erich Seifritz, Sebastian Olbrich
Reward processing is impaired in people with schizophrenia, which may begin in the clinical high-risk (CHR) for psychosis period. The Monetary Incentive Delay (MID) task has been important in understanding the neural correlates of reward …
verfasst von:
D. N. Pratt, M. T. Treadway, G. P. Strauss, V. A. Mittal
The coronavirus disease 2019 (COVID-19) pandemic was accompanied by an increase in mental health challenges including depression, stress, loneliness, and anxiety. Common genetic variants can contribute to the risk for psychiatric disorders and may …
verfasst von:
Alicia M. Schowe, Malvika Godara, Darina Czamara, Mazda Adli, Tania Singer, Elisabeth B. Binder
Post-COVID syndrome (PCS) is characterized by a variety of non-specific symptoms. One of the leading symptoms is fatigue. So far, there is no evidence-based causal therapy established and treatment of PCS is primarily symptom-oriented. The Clinic …
verfasst von:
Sarah Schmid, Christine Uecker, Antje Fröhlich, Jost Langhorst
Non-invasive brain stimulation is a promising new treatment approach for Major Depressive Disorder (MDD). Repetitive Transcranial Magnetic Stimulation (rTMS) [ 1 , 2 ], a stimulation technique aimed at the activation of local brain regions through …
verfasst von:
Sjoerd M. van Belkum, Esther M. Opmeer, Hanneke Geugies, Marrit K. de Boer, Robert A. Schoevers, André Aleman
Previous studies about anhedonia symptoms in bipolar depression (BD) ignored the unique role of gender on brain function. This study aims to explore the regional brain neuroimaging features of BD with anhedonia and the sex differences in these …
Anxiety and depressive disorders have overlapping symptoms and share common neurobiological pathways. Antidepressant drugs have been demonstrated to be efficacious in anxiety as well. Vice versa, it may also be promising to investigate the …
verfasst von:
Siegfried Kasper, Hans-Peter Volz, Hans-Jürgen Möller, Sandra Schläfke, Stephan Klement, Ion-George Anghelescu, Erich Seifritz
The individual’s mental health crisis and the COVID-19 pandemic lead to mental disorders. The transmission of the COVID-19 virus is associated with the levels of anxiety, stress, and depression in individuals, similar to other factors. Increases …
Breast cancer is one of the most prevalent and serious types of cancer globally. Previous literature has shown that women with mental illness may have an increased risk of breast cancer, however whether this risk is associated with the use of …
Exercise interventions are nowadays considered as effective add-on treatments in people with schizophrenia but are usually associated with high dropout rates. Therefore, the present study investigated potential predictors of adherence from a large …
verfasst von:
Rebecca Schwaiger, Isabel Maurus, Moritz Lembeck, Irina Papazova, David Greska, Susanne Muenz, Eliska Sykorova, Cristina E. Thieme, Bob O. Vogel, Sebastian Mohnke, Charlotte Huppertz, Astrid Roeh, Katriona Keller-Varady, Berend Malchow, Henrik Walter, Bernd Wolfarth, Wolfgang Wölwer, Karsten Henkel, Dusan Hirjak, Andrea Schmitt, Alkomiet Hasan, Andreas Meyer-Lindenberg, Peter Falkai, Lukas Roell
After over a hundred years of research, the question whether the symptoms of schizophrenia are rather trait-like (being a relatively stable quality of individuals) or state-like (being substance to change) is still unanswered. To assess the trait …
verfasst von:
Jana S. Krückl, Károly Acsai, Zsófia B. Dombi, Julian Moeller, Roselind Lieb, Undine E. Lang, Ágota Barabássy, Christian G. Huber
Several studies have reported that baseline symptom severity in patients with schizophrenia (SCZ) is associated with the efficacy of antipsychotic medication. Overweight/obesity is common in SCZ and has also been reported to be correlated with …
Individuals with a history of childhood abuse (CA, including neglect and abuse by caregivers before the age of 18 years) have more severe substance dependence problems than those without a history of childhood abuse. However, whether a history of …
verfasst von:
Jiajing Chen, Dong Mei Wang, Yang Tian, Rongrong Zhu, Yuqing Li, Lianglun Jia, Fabing Fu, Shanshan Tang, Xiaotao Wang, Li Wang, Xiang Yang Zhang
The co-occurrence of psychopathological symptoms stemming from different functional domains is characteristic of psychiatric disorders. For instance, schizophrenia spectrum disorders (SSD) are characterized by psychopathological symptoms from …
verfasst von:
Stefan Fritze, Geva A. Brandt, Sebastian Volkmer, Jonas Daub, Maria Krayem, Jacqueline Kukovic, Emanuel Schwarz, Urs Braun, Georg Northoff, Robert Christian Wolf, Katharina M. Kubera, Andreas Meyer-Lindenberg, Dusan Hirjak
