Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers (ACEi/ARBs) are commonly used anti-hypertensive drugs. Recent hypertension guidelines recommend dual combination therapy including ACEi/ARBs as an initial form of …
verfasst von:
Jaeyun Lee, Chan-Young Jung, Hyosang Kim, Hwa Jung Kim, Youngmin Ko, Hyunwook Kwon, Sung Shin, Young Hoon Kim, Su-Kil Park, Chung Hee Baek
Alport syndrome has been linked to three different genes, that is, COL4A3, COL4A4 and COL4A5. It is characterized by progressive and non-specific glomerulosclerosis with irregular thickening of the glomerular basement membrane (GBM). At times, the …
verfasst von:
Nicolas A. D. Bergeron, Alexandre P. Garneau, Mathieu Rousseau-Gagnon, Julie Riopel, Paul Isenring
Patients undergoing maintenance hemodialysis experience a range of symptom clusters and economic burdens, resulting in a lower health-related quality of life (HRQOL) compared to their healthy counterparts [ 1 ]. Physical activity refers to any body …
Patient 1, a 33-year-old woman, was referred to our Unit in November 2018. The patient suffered from recurrent abdominal pain starting from menarche. The crises were not regularly connected with menstrual cycles. During the acute crises, this pain …
verfasst von:
Claudio Carmine Guida, Angela Maria Pellegrino, Aurora Del Mar Perez Ys, Filippo Aucella, CSS Porphiria Study Group
Taiwan has the highest incidence of end-stage kidney disease (ESKD) worldwide. The prevalence of ESKD reached 3546 per million people by 2021 [ 1 ]. Furthermore, at least 20% of Taiwan’s population consists of elderly people, making it an …
More than one billion people worldwide are obese. Obesity leads to multiple complications and results in over 2.8 million deaths yearly [ 1 , 2 ].
verfasst von:
Thaysa Sobral Antonelli, Milena dos Santos Mantovani, Nyara Coelho de Carvalho, Thomáz Eduardo Archangelo, Marcos Ferreira Minicucci, Sebastião Pires Ferreira Filho, Ricardo de Souza Cavalcante, Luis Gustavo Modelli de Andrade, Nara Aline Costa, Paulo Roberto Kawano, Gabriel Berg de Almeida, Silvia Justina Papini, Ricardo Augusto Monteiro de Barros Almeida
Leukocyte chemotactic factor-2 amyloidosis (ALECT2) is a recently described subtype of amyloidosis. IgG4-related disease is a rare fibroinflammatory condition characterized by dense interstitial lymphoplasmacytic infiltrates and fibrosis.
verfasst von:
Muhammad Shaheen, Anchit Bharat, Allon N. Friedman, Shunhua Guo
Osteoporosis and osteopenia are more frequent in kidney transplant recipients than in healthy individuals. Bone mineral density in kidney transplant recipients decreases by 4 − 10% during the first 6 months after transplantation [ 1 ], followed by …
Chronic kidney disease (CKD) patients have an increased risk for cognitive impairment compared to the general population. The risk is much higher in CKD patients who progress to end-stage kidney disease (ESKD) and require hemodialysis or …
Nutcracker syndrome is a relatively rare disorder, most often caused by the compression of the left renal vein between the abdominal aorta and superior mesenteric artery [ 1 ]. Renal Doppler ultrasonography is often the initial option for the …
verfasst von:
Hui Tang, Xianchao Yu, Qun Chen, Yuexing Zhu, Shikun Zhang, Lu Tang, Yinghong Zhao, Gang Hua, Jinqiu Hu
Atherosclerosis is the leading cause of renal artery stenosis. The epidemiology of atherosclerotic renovascular disease varies depending on the cohort studied and the screening tool used. The prevalence amongst the overall US Medicare population …
verfasst von:
Áine M. de Bhailis, Edward Lake, Constantina Chrysochou, Darren Green, Rajkumar Chinnadurai, Philip A. Kalra
Impaired physical function represents a rising public health concern in the aging population, as it is associated with increased rates of morbidity and mortality [ 1 ]. Loss of muscle strength and the development of sarcopenia have been linked to …
verfasst von:
Ioannis Bellos, Smaragdi Marinaki, Pagona Lagiou, Ioannis N. Boletis, Annemarie Koster, Marleen M. J. van Greevenbroek, Simone J. P. M. Eussen, Hans H. C. M. Savelberg, Anke Wesselius, Vassiliki Benetou
A 60-year-old male was hospitalized for acute kidney injury (AKI) after 2 weeks of lower abdominal pain and fatigue, though without flank pain. His medical history was unremarkable; two weeks earlier he began taking omeprazole 20 mg once daily for …
verfasst von:
Matteo Righini, Benedetta Fabbrizio, Giovanna Cenacchi, Andrea Buscaroli
Direct Oral Anticoagulants (DOACs) are the first-line anticoagulation therapy prescribed for venous thromboembolism and atrial fibrillation patients with normal kidney function or moderately severe chronic kidney disease (CKD) [ 1 ]. The volume of …
verfasst von:
Ezekwesiri Michael Nwanosike, Hamid A. Merchant, Wendy Sunter, Muhammad Ayub Ansari, Barbara R. Conway, Syed Shahzad Hasan
As recently as a decade ago, saline was the first-choice resuscitation fluid in critically ill patients [ 1 , 2 ]. As more data became available demonstrating the possible harmful effects of saline, its use diminished and balanced solutions …
verfasst von:
M. Raes, J. A. Kellum, R. Colman, S. Wallaert, M. Crivits, F. Viaene, M. Hemeryck, D. Benoit, J. Poelaert, E. Hoste
A 24-year-old woman of Iraqi descent was referred to a nephrologist because of the incidental finding of chronic kidney disease stage 3 (estimated glomerular filtration rate 58 ml/min/1.73 m 2 , CKD-EPI) with microscopic hematuria and proteinuria …
Hemodialysis (HD) is a life-saving therapy for end-stage kidney disease patients. Nevertheless, it is not a physiological treatment since it guarantees blood purification and water removal but does not achieve complete rehabilitation of the …
