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Cardiovascular Toxicology
Erschienen in: Cardiovascular Toxicology 3/2022

20.08.2021

Long Non-coding RNAs: Potential Players in Cardiotoxicity Induced by Chemotherapy Drugs

verfasst von: Mehran Amrovani, Mohammadjavad Mohammadtaghizadeh, Mahsa Karimzadeh Aghaali, Somayeh Zamanifard, Arash Alqasi, Mozhdeh Sanei

Erschienen in: Cardiovascular Toxicology | Ausgabe 3/2022

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Abstract

One of the most important side effects of chemotherapy is cardiovascular complications, such as cardiotoxicity. Many factors are involved in the pathogenesis of cardiotoxicity; one of the most important of which is long non-coding RNAs (lncRNAs). lncRNA has 200–1000 nucleotides. It is involved in important processes such as cell proliferation, regeneration and apoptosis; today it is used as a prognostic and diagnostic factor. A, various drugs by acting on lncRNAs can affect cells. Therefore, by accurately identifying IncRNAs function, we can play an effective role in preventing the development of cardiotoxicity-induced chemotherapy drugs, and use them as a therapeutic strategy to improve clinical symptoms and increase patient survival.
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Metadaten
Titel
Long Non-coding RNAs: Potential Players in Cardiotoxicity Induced by Chemotherapy Drugs
verfasst von
Mehran Amrovani
Mohammadjavad Mohammadtaghizadeh
Mahsa Karimzadeh Aghaali
Somayeh Zamanifard
Arash Alqasi
Mozhdeh Sanei
Publikationsdatum
20.08.2021
Verlag
Springer US
Erschienen in
Cardiovascular Toxicology / Ausgabe 3/2022
Print ISSN: 1530-7905
Elektronische ISSN: 1559-0259
DOI
https://doi.org/10.1007/s12012-021-09681-y

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