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European Journal of Applied Physiology

Erschienen in:

01.08.2015 | Original Article

Lung volume and expiratory flow rates from pre- to post-puberty

verfasst von: Joshua R. Smith, Sam R. Emerson, Stephanie P. Kurti, Kirti Gandhi, Craig A. Harms

Erschienen in: European Journal of Applied Physiology | Ausgabe 8/2015

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Abstract

Purpose

The purpose was to determine if the airways and lungs grow disproportionately from pre- to post-puberty in boys and girls. We hypothesized that the airways grow at a slower rate than lung volume (i.e. dysanapsis growth) during puberty and boys would exhibit more dysanaptic growth compared to girls.

Methods

Twenty-one pre-pubescent children [11 boys (pre 10.1 ± 0.5 years, post 15.3 ± 0.5 years); 10 girls (pre 9.4 ± 1.0 years, post 14.1 ± 1.0 years)] performed pulmonary function tests (PFTs) ~5 years ago from an original cohort of 40 children. These 21 children performed PFTs, which included forced vital capacity (FVC) and forced expiratory flow at 50 % FVC (FEF₅₀). Static pressure at 50 % of FVC [Pst(L)_50 %] was estimated based on age. Dysanapsis ratio (DR) was calculated [FEF₅₀ × FVC⁻¹ × Pst(L) _50 % ⁻¹ ]. Maturation status was determined via Tanner stages.

Results

Stage of maturation was not different (p > 0.05) between boys and girls (4.2 ± 0.6 stage vs. 3.7 ± 0.7 stage, respectively). FVC and FEF₅₀ increased (p < 0.05), DR significantly decreased, and FEF₅₀/FVC was similar (p > 0.05) from pre- to post-puberty. FEF₅₀ and FVC significantly increased and DR decreased (p < 0.05) post-puberty for both sexes. Post-puberty, boys had a significantly larger FVC, but FEF₅₀, DR, and FEF₅₀/FVC were not different (p > 0.05) compared to girls.

Conclusions

These data suggest that dysanaptic growth occurs during puberty and that it is not different between boys and girls.

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Titel: Lung volume and expiratory flow rates from pre- to post-puberty
verfasst von: Joshua R. Smith
Sam R. Emerson
Stephanie P. Kurti
Kirti Gandhi
Craig A. Harms
Publikationsdatum: 01.08.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Applied Physiology / Ausgabe 8/2015
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-015-3149-1

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Abstract

Purpose

Methods

Results

Conclusions

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