Background
Methods
Subjects
OCTA scanning data acquisition and processing
Statistical analysis
Results
Items | XT group Mean ± SD/ Numbers (%) | IXT group Mean ± SD/ Numbers (%) | Control group Mean ± SD/ Numbers (%) | p value |
---|---|---|---|---|
Age (yrs) | 12.88 ± 5.82 | 10.83 ± 5.16 | 10.19 ± 2.83 | 0.133 |
Sex | 0.057 | |||
Female | 4 (25) | 9 (37.50) | 21 (58.33) | |
Male | 12 (75) | 15 (62.50) | 15 (41.67) | |
Spherical equivalent, D* | −1.17 ± 1.73 | −1.69 ± 2.58 | −2.09 ± 1.46 | 0.283 |
Angle of deviation, PD | ||||
N | 39.06 ± 10.38 | 27.13 ± 18.28 | < 0.001 | |
D** | 43.00 ± 9.74 | 31.04 ± 18.82 | < 0.001 |
Items | XT group | p | IXT group | p | Control group | p | |||
---|---|---|---|---|---|---|---|---|---|
Study eye | Control eye | Study eye | Control eye | Study eye | Control eye | ||||
6 × 6-mm OCTA macular scans | |||||||||
SCP (%, Mean ± SD) | 50.38 ± 2.42 | 51.04 ± 2.44 | 0.232 | 50.81 ± 2.45 | 50.12 ± 2.90 | 0.216 | 51.04 ± 2.49 | 50.73 ± 2.04 | 0.400 |
DCP (%, Mean ± SD) | 43.81 ± 3.24 | 52.38 ± 4.86 | < 0.001 | 47.22 ± 6.89 | 49.04 ± 7.27 | 0.190 | 51.09 ± 5.30 | 50.86 ± 4.42 | 0.805 |
3 × 3-mm OCTA macular scans | |||||||||
SCP (%, Mean ± SD) | 47.12 ± 1.90 | 48.77 ± 2.18 | 0.032 | 47.76 ± 2.82 | 48.63 ± 2.21 | 0.055 | 48.26 ± 2.34 | 48.20 ± 2.48 | 0.901 |
DCP (%, Mean ± SD) | 51.22 ± 3.60 | 52.69 ± 4.10 | 0.193 | 51.13 ± 4.19 | 51.62 ± 3.45 | 0.471 | 53.83 ± 2.54 | 54.15 ± 2.65 | 0.413 |
FAZ parameters | |||||||||
Area (mm2) | 0.25 ± 0.10 | 0.26 ± 0.11 | 0.350 | 0.27 ± 0.09 | 0.30 ± 0.09 | 0.114 | 0.27 ± 0.10 | 0.27 ± 0.09 | 0.653 |
Perimeter (mm) | 1.95 ± 0.43 | 2.00 ± 0.42 | 0.389 | 2.02 ± 0.34 | 2.09 ± 0.38 | 0.161 | 2.05 ± 0.36 | 1.99 ± 0.45 | 0.351 |
AI | 1.12 ± 0.03 | 1.14 ± 0.06 | 0.225 | 1.12 ± 0.04 | 1.13 ± 0.04 | 0.172 | 1.12 ± 0.03 | 1.13 ± 0.06 | 0.358 |
Macular thickness (μm, Mean ± SD) | 310.00 ± 15.69 | 307.94 ± 16.18 | 0.119 | 312.71 ± 13.60 | 313.13 ± 14.14 | 0.638 | 308.03 ± 12.94 | 309.22 ± 13.85 | 0.078 |
Items | XT vs Control group | IXT vs Control group | XT vs IXT group |
---|---|---|---|
(95% CI) | (95% CI) | (95% CI) | |
6 × 6-mm OCTA macular scans | |||
SCP (%,Mean ± SD) | −0.66 (− 2.14, 0.81) | − 0.23 (− 1.56, 1.10) | −0.43 (− 2.05, 1.18) |
DCP (%,Mean ± SD) | −7.28* (− 10.57, −3.99) | −3.86* (−6.83, − 0.90) | −3.42 (− 7.01, 0.18) |
3 × 3-mm OCTA macular scans | |||
SCP (%,Mean ± SD) | − 1.14 (− 2.59, 0.31) | − 0.49 (− 1.77, 0.78) | −0.64 (− 2.20, 0.91) |
DCP (%,Mean ± SD) | −2.61* (− 4.62, − 0.60) | −2.70* (− 4.46, − 0.93) | 0.09 (− 2.07, 2.24) |
FAZ parameters | |||
Area (mm2) | −0.032 (− 0.084, 0.025) | −0.006 (− 0.055, 0.042) | −0.024 (− 0.084, 0.035) |
Perimeter (mm) | − 0.099 (− 0.320, 0.121) | −0.028 (− 0.221, 0.166) | −0.071 (− 0.308, 0.165) |
AI | 0.005 (− 0.015, 0.024) | 0.002 (− 0.015, 0.019) | 0.003 (− 0.018, 0.024) |
Macular thickness (μm, Mean ± SD) | 1.972 (− 6.266, 10.210) | 4.681 (− 2.545, 11.906) | −2.708 (− 11.557, 2.545) |