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Erschienen in: Pediatric Surgery International 1/2023

01.12.2023 | Original Article

Management of non-functioning kidney due to pelvi-ureteric junction obstruction in pediatric age group: an observational study

verfasst von: Rahul Kumar Rai, Anand Pandey, Shashwat Verma, Nitin Pant, Sudhir Singh, Nirpex Tyagi, Piyush Kumar, Jiledar Rawat

Erschienen in: Pediatric Surgery International | Ausgabe 1/2023

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Abstract

Introduction

A non-functional kidney (NFK) has been defined as one having paper-thin parenchyma, and split renal function (SRF) of < 10% on a nuclear scan. There are differences of opinion about nephrectomy or pyeloplasty in these patients. The present study was conducted to assess our management strategy of renal salvage for NFK.

Materials and methods

It was a retrospective cohort study from January 2015 to July 2022, patients having SRF < 10% were included. These patients underwent ultrasound-guided percutaneous nephrostomy (PCN). A repeat nuclear scan was performed after 3 months. If SRF increased to > 10%, pyeloplasty was performed.

Results

Fifteen patients were managed. The mean age was 24.67 ± 23.61 months. Male to female ratio was 4:1. The initial mean SRF was 6.67 ± 2.85, which improved to 16.80 ± 4.69 after 3 months of placing the PCN (p < 0.001). The corresponding changes in the mean effective renal plasma flow (ERPF) were 60.13 ± 24.08 to 106.53 ± 24.61 (p < 0.001). There was no complaint after the placement of PCN. All patients underwent dismembered pyeloplasty.

Conclusion

In NFK due to PUJO, expectant treatment in form of PCN followed by pyeloplasty appears to be the primary treatment modality, and nephrectomy may not be needed in any of them.
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Literatur
4.
Zurück zum Zitat Dhillon HK (1998) Prenatally diagnosed hydronephrosis: the great ormond street experience. Br J Urol 81(Suppl 2):39e44 Dhillon HK (1998) Prenatally diagnosed hydronephrosis: the great ormond street experience. Br J Urol 81(Suppl 2):39e44
5.
Zurück zum Zitat Thorup J, Jokela R, Cortes D, Nielsen OH (2003) The results of 15 years of consistent strategy in treating antenatally suspected pelvi-ureteric junction obstruction. BJU Int 91:850e2CrossRef Thorup J, Jokela R, Cortes D, Nielsen OH (2003) The results of 15 years of consistent strategy in treating antenatally suspected pelvi-ureteric junction obstruction. BJU Int 91:850e2CrossRef
8.
Zurück zum Zitat Abbas T, Elifranji M, Al-Salihi M, Ahmad J, Vallasciani S, Elkadhi A, Özcan C, Burgu B, Akinci A, Alnaimi A, Salle JLP (2022) Functional recoverability post-pyeloplasty in children with ureteropelvic junction obstruction and poorly functioning kidneys: systematic review. J Pediatr Urol 21:S1477-5131(22)00313–8. https://doi.org/10.1016/j.jpurol.2022.07.009CrossRef Abbas T, Elifranji M, Al-Salihi M, Ahmad J, Vallasciani S, Elkadhi A, Özcan C, Burgu B, Akinci A, Alnaimi A, Salle JLP (2022) Functional recoverability post-pyeloplasty in children with ureteropelvic junction obstruction and poorly functioning kidneys: systematic review. J Pediatr Urol 21:S1477-5131(22)00313–8. https://​doi.​org/​10.​1016/​j.​jpurol.​2022.​07.​009CrossRef
12.
Zurück zum Zitat Elmore J, Kirsch AJ (2007) Assessment of renal obstructive disorders: ultrasound, nuclear medicine, and magnetic resonance imaging. In: Docimo SJ, Canning DA, Khoury AA (eds) The Kelalis–King–Belman book of clinical pediatric urology, informa Health care, 5th edn. Abingdon Oxon, London, pp 447–60 Elmore J, Kirsch AJ (2007) Assessment of renal obstructive disorders: ultrasound, nuclear medicine, and magnetic resonance imaging. In: Docimo SJ, Canning DA, Khoury AA (eds) The Kelalis–King–Belman book of clinical pediatric urology, informa Health care, 5th edn. Abingdon Oxon, London, pp 447–60
13.
Zurück zum Zitat Hephzibah J (2018) Role of nuclear medicine in evaluation of renal system. Curr Med Issues 16:148–154CrossRef Hephzibah J (2018) Role of nuclear medicine in evaluation of renal system. Curr Med Issues 16:148–154CrossRef
14.
Zurück zum Zitat Bassiouny IE (1992) Salvage pyeloplasty in non visualizing hydronephrotic kidney secondary to ureteropelvic junction obstruction. J Urol 148:685e7CrossRef Bassiouny IE (1992) Salvage pyeloplasty in non visualizing hydronephrotic kidney secondary to ureteropelvic junction obstruction. J Urol 148:685e7CrossRef
15.
Zurück zum Zitat Sharma G, Sharma A, Leung VY-F, Chu WC-W (2016) Is decreased diameter of renal pelvis in prone position an indicator of successful pyeloplasty? Indian J Radiol Imag 26:1521 Sharma G, Sharma A, Leung VY-F, Chu WC-W (2016) Is decreased diameter of renal pelvis in prone position an indicator of successful pyeloplasty? Indian J Radiol Imag 26:1521
16.
Zurück zum Zitat Gnech M, Berrettini A, Lopes RI, Moscardi P, Esposito C, Zucchetta P, Dénes FT, Manzoni G, Braga LH, Castagnetti M (2019) Pyeloplasty vs. nephrectomy for ureteropelvic junction obstruction in poorly functioning kidneys (differential renal function < 20%): a multicentric study. J Pediatr Urol 15:553.e1-553.e8CrossRefPubMed Gnech M, Berrettini A, Lopes RI, Moscardi P, Esposito C, Zucchetta P, Dénes FT, Manzoni G, Braga LH, Castagnetti M (2019) Pyeloplasty vs. nephrectomy for ureteropelvic junction obstruction in poorly functioning kidneys (differential renal function < 20%): a multicentric study. J Pediatr Urol 15:553.e1-553.e8CrossRefPubMed
17.
Zurück zum Zitat Menon P, Rao KL, Bhattacharya A, Mittal BR (2016) Outcome analysis of pediatric pyeloplasty in units with less than 20% differential renal function. J Pediatr Urol 12:171.e1–7CrossRefPubMed Menon P, Rao KL, Bhattacharya A, Mittal BR (2016) Outcome analysis of pediatric pyeloplasty in units with less than 20% differential renal function. J Pediatr Urol 12:171.e1–7CrossRefPubMed
18.
Zurück zum Zitat Rudrawadi S, Kochhar G, Shekhar PA, Laddha PJ (2021) Does preoperative function affect the outcome following pyeloplasty in poorly functioning kidneys among pediatric population? J Indian Assoc Pediatr Surg 26:294–298CrossRefPubMedPubMedCentral Rudrawadi S, Kochhar G, Shekhar PA, Laddha PJ (2021) Does preoperative function affect the outcome following pyeloplasty in poorly functioning kidneys among pediatric population? J Indian Assoc Pediatr Surg 26:294–298CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Sarhan O, Al Otay A, Al Faddagh A, El Helaly A, Al Hagbani M, Al Ghanbar M, Al Kawai F, Nakshabandi Z (2021) Pyeloplasty in children with low differential renal function: Functional recoverability. J Pediatr Urol 17:658.e1-658.e9CrossRefPubMed Sarhan O, Al Otay A, Al Faddagh A, El Helaly A, Al Hagbani M, Al Ghanbar M, Al Kawai F, Nakshabandi Z (2021) Pyeloplasty in children with low differential renal function: Functional recoverability. J Pediatr Urol 17:658.e1-658.e9CrossRefPubMed
20.
Zurück zum Zitat Shahrokh H, Movahhed M, Zargar Shoshtari MA, Orafa AM, Hekmat S (2006) Ethylenedicysteine versus diethylenetriaminepentaacetic acid as the carrier of technetium Tc 99m in diuretic renography for patients with upper urinary tract obstruction. Urol J Spring 3:97–103 Shahrokh H, Movahhed M, Zargar Shoshtari MA, Orafa AM, Hekmat S (2006) Ethylenedicysteine versus diethylenetriaminepentaacetic acid as the carrier of technetium Tc 99m in diuretic renography for patients with upper urinary tract obstruction. Urol J Spring 3:97–103
21.
Zurück zum Zitat Wagner M, Mayr J, Häcker FM (2008) Improvement of renal split function in hydronephrosis with less than 10% function. Eur J Pediatr Surg 18:156–159CrossRefPubMed Wagner M, Mayr J, Häcker FM (2008) Improvement of renal split function in hydronephrosis with less than 10% function. Eur J Pediatr Surg 18:156–159CrossRefPubMed
Metadaten
Titel
Management of non-functioning kidney due to pelvi-ureteric junction obstruction in pediatric age group: an observational study
verfasst von
Rahul Kumar Rai
Anand Pandey
Shashwat Verma
Nitin Pant
Sudhir Singh
Nirpex Tyagi
Piyush Kumar
Jiledar Rawat
Publikationsdatum
01.12.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Surgery International / Ausgabe 1/2023
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-023-05368-3

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