Metformin

Excerpt

A 45-year-old woman experienced insomnia following treatment with metformin for diabetes mellitus. The woman received oral metformin 500 mg/day, every morning, for diabetes mellitus; on the third day following metformin ingestion, she experienced significant insomnia. One week later, she presented for metformin-induced insomnia. Metformin was replaced with glibenclamide, and her insomnia resolved. She experienced recurrent insomnia following metformin re-administration.Author Comment“[T]his seems to be a probable case of an actual metformin-induced insomnia.“ …