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01.12.2023 | Original Article

Perianal abscess in children: an evaluation of microbiological etiology and the effectiveness of antibiotics

verfasst von: Gizem Guner Ozenen, Aybuke Akaslan Kara, Arife Ozer, Pelin Kacar, Deniz Ergun, Aysenur Aydin, Incinur Genisol Ataman, Kamer Polatdemir, Ayse Demet Payza, Yelda Sorguc, Akgun Oral, Nuri Bayram, Ilker Devrim

Erschienen in: Pediatric Surgery International | Ausgabe 1/2023

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Abstract

Purpose

We aimed to evaluate the demographic characteristics of children with perianal abscess, distribution of microbiological etiology, antibiotic susceptibility, and identify the effectiveness and coverage of antibiotics due to culture results.

Methods

A retrospective study was designed to evaluate pediatric patients with perianal abscesses between January 2013 and December 2022.

Results

A total of 197 episodes in 135 patients were evaluated. The median age of the patients was 10 months (22 days–17 years). The isolated microorganisms were Gram-positive bacteria in 56 (28.4%) patients and Gram-negative bacteria in 141 (71.6%) patients. The most common isolated species was Escherichia coli (n = 70, 35.5%), followed by Klebsiella spp. (n = 48, 24.4%), Staphylococcus aureus (n = 37, 18.9%), and Enterobacter spp. (n = 9, 4.5%). Forthy-two percent (n = 58) of isolates were positive for extended-spectrum beta-lactamase, 8% (n = 11) were carbapenem-resistant in Gram-negative bacteria, and 37.5% (n = 21) were methicillin-resistant, 7.1% (n = 4) were vancomycin-resistant in Gram-positive bacteria. According to bacterial culture results, ertapenem plus glycopeptide had the highest antimicrobial coverage rate (92.3%), followed by ertapenem plus clindamycin (89.8%), ertapenem (81.7%), third-generation cephalosporin plus glycopeptide (82.2%), third-generation cephalosporin plus clindamycin (69.5%).

Conclusion

Ertapenem can be a good choice in the empirical treatment of perianal abscesses in children due to its high coverage rate.

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Titel: Perianal abscess in children: an evaluation of microbiological etiology and the effectiveness of antibiotics
verfasst von: Gizem Guner Ozenen
Aybuke Akaslan Kara
Arife Ozer
Pelin Kacar
Deniz Ergun
Aysenur Aydin
Incinur Genisol Ataman
Kamer Polatdemir
Ayse Demet Payza
Yelda Sorguc
Akgun Oral
Nuri Bayram
Ilker Devrim
Publikationsdatum: 01.12.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Surgery International / Ausgabe 1/2023
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-023-05556-1

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Perianal abscess in children: an evaluation of microbiological etiology and the effectiveness of antibiotics