Pirfenidone

Excerpt

A woman in her late 60s [exact age not stated] developed malaise, nausea and vomiting during treatment with pirfenidone for idiopathic pulmonary fibrosis (IPF). The woman had undergone bilateral lung transplantation for IPF, in March 2006, at the age of 59 years. In 2012, she started receiving azithromycin for bronchiolitis obliterans syndrome. In December 2015, she started receiving pirfenidone [route and dosage not stated] due to worsening of FEV1 function. She developed malaise, nausea and vomiting, and pirfenidone was stopped after one month. The ADRs were attributed to pirfenidone. …