Background
Methods
Subjects
Study design
Evaluation of small intestinal mucosal lesions
Sample size
Statistical analysis
Results
Group A (n = 12) | Group B (n = 12) | p value | |
---|---|---|---|
Age, mean ± SD | 36.0 ± 6.69 | 36.8 ± 5.99 | 0.7749† |
Gender, male, n (%) | 12 (100%) | 11 (91.67%) | 0.3070‡ |
Height, cm, mean ± SD | 172.8 ± 1.73 | 172.2 ± 1.73 | 0.7874† |
Weight, kg, mean ± SD | 72.8 ± 2.51 | 73.0 ± 2.51 | 0.9630† |
Smoking history, n (%) | 4 (33.3%) | 4 (33.3%) | 1.000‡ |
Drinking history, n (%) | 1 (8.3%) | 1 (8.3%) | 1.000‡ |
Baseline | After LDA administration | p value | ||
---|---|---|---|---|
Total small intestine | Spotty redness, median (range) | 0 (0–3) | 2 (0–8) | 0.0039† |
Patchy redness, median (range) | 1 (0–3) | 1 (0–6) | 0.2539† | |
Erosion, median (range) | 0 (0–1) | 0 (0–4) | 0.1250† | |
All types of lesions, median (range) | 1 (0–5) | 5 (1–11) | 0.0059† | |
The first tertile of the small intestine All types of lesions, median (range) | ||||
0 (0–2) | 2 (0–8) | 0.0313† | ||
The second and third tertiles of the small intestine All types of lesions, median (range) | ||||
0 (0–4) | 2 (0–6) | 0.0156† |
Baseline | After LDA administration | p value | ||
---|---|---|---|---|
Total small intestine | Spotty redness, median (range) | 0 (0–6) | 1.5 (0–13) | 0.1250† |
Patchy redness, median (range) | 0 (0–3) | 1.5 (0–2) | 0.3711† | |
Erosion, median (range) | 0 (0–0) | 0 (0–9) | 0.5000† | |
All types of lesions, median (range) | 0.5 (0–9) | 3 (0–23) | 0.0586† | |
First tertile of small intestine All types of lesions, median (range) | ||||
0 (0–4) | 1.5 (0–8) | 0.2969† | ||
Second and third tertiles of the small intestine All types of lesions, median (range) | ||||
0 (0–5) | 2 (0–15) | 0.0469† |
Group A | Group B | p value | ||
---|---|---|---|---|
Total small intestine | Spotty redness, mean ± SD | 0.50 ± 1.00 | 1.0 ± 1.86 | 0.4206† |
Patchy redness, mean ± SD | 0.83 ± 0.94 | 0.75 ± 1.06 | 0.8398† | |
Erosion, mean ± SD | 0.17 ± 0.39 | 0.0 ± 0.00 | 0.1522† | |
All types of lesions, mean ± SD | 1.50 ± 1.62 | 1.75 ± 2.67 | 0.7841† | |
First tertile of small intestine All types of lesions, mean ± SD | ||||
0.58 ± 0.79 | 0.75 ± 1.29 | 0.7063† | ||
Second and third tertiles of the small intestine All types of lesions, mean ± SD | ||||
0.92 ± 1.38 | 1.00 ± 1.54 | 0.8901† |
Group A | Group B | p value | ||
---|---|---|---|---|
Total small intestine | Spotty redness, mean ± SD | 2.58 ± 2.27 | 2.75 ± 3.77 | 0.8968† |
Patchy redness, mean ± SD | 1.83 ± 2.08 | 1.17 ± 0.94 | 0.3227† | |
Erosion, mean ± SD | 0.92 ± 1.38 | 0.83 ± 2.59 | 0.9225† | |
All types of lesions, mean ± SD | 5.33 ± 3.60 | 4.92 ± 6.07 | 0.8398† | |
First tertile of small intestine All types of lesions, mean ± SD | 2.67 ± 2.71 | 1.92 ± 2.46 | 0.4856† | |
Second and third tertiles of the small intestine All types of lesions, mean ± SD | 2.67 ± 1.92 | 2.83 ± 4.02 | 0.8981† |