Nowadays, the leading causes of morbidity and mortality in the globe are the development of chronic non-communicable diseases (NCDs) such as cardiovascular diseases (CVDs), overweight, obesity, diabetes, hypertension, and cancer types [
1]. Lifestyle modification programs using an integration of effective interventions including regular physical activity (PA), proper nutrition, and stress management can significantly decrease the long term risks associated with modern chronic diseases [
1‐
4]. Physical inactivity is rapidly increasing in low- to middle-income countries [
4]. There is a considerable variety of physical inactivity in different geographical regions of the world because this risk factor is highly influenced by age, gender, health status, self-efficacy (SE), and motivation [
3,
5]. Based on the data disseminated by the World Health Organization, the inadequate PA caused 9% of the global deaths [
6]. Furthermore, regular physical inactivity has been the main risk factor for 21–25% of breast and colon cancers, 27% of diabetes, and 30% of CVDs [
7]. CVDs are the most critical consequence of physical inactivity [
8]. In 2016, the US healthcare system spent over $315.4 billion on CVDs and stroke caused by a sedentary lifestyle [
9]. According to the information released about the disadvantages of a sedentary lifestyle, most Iranians are in a state of extreme immobility. Findings show that more than 80% of Iran's population are physically inactive (less than 90 min per week for 3 months) [
10]. Since the Iranian people are moving towards aging, it is not far-fetched to predict the increase in burden of chronic diseases and their risk factors [
11]. It is anticipated that by 2050, approximately 20% of the worldwide population will be women older than 50 years old [
12]. Besides, according to the Population and Housing Censuses 2016, 8.5 million 40-64-year-old women with very little PA are living in Iran [
13]. The health status of middle-aged people in the society can be effectively improved using an integrated behavior change model as a visible and replicable interventional tool through implementing empirical and theoretical aims, program development, feedback, and monitoring [
14]. These interventions may involve a large number of population groups according to the integration of demographic parameters such as gender, age, marital and parenting status, and socioeconomic situation. Hence, the in-depth understanding and knowledge of the unique characteristics of individuals (such as values, motivators, preferences, and challenges) are necessary to plan an efficient intervention for promoting the PA level [
15]. Accordingly, designing behavior change programs and promoting PA allow middle-aged Iranian women (MGIW) to understand the impact of their behavior on health and to make decisions about having a healthy life. Consequently, the present study is aimed to choose and assess a suitable and indigenous model to promote the PA of MAIW.