nach oben

European Journal of Applied Physiology

Erschienen in:

Open Access 25.10.2017 | Original Article

Satellite cell response to concurrent resistance exercise and high-intensity interval training in sedentary, overweight/obese, middle-aged individuals

verfasst von: Jamie K. Pugh, Steve H. Faulkner, Mark C. Turner, Myra A. Nimmo

Erschienen in: European Journal of Applied Physiology | Ausgabe 2/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Sarcopenia can begin from the 4–5th decade of life and is exacerbated by obesity and inactivity. A combination of resistance exercise (RE) and endurance exercise is recommended to combat rising obesity and inactivity levels. However, work continues to elucidate whether interference in adaptive outcomes occur when RE and endurance exercise are performed concurrently. This study examined whether a single bout of concurrent RE and high-intensity interval training (HIIT) alters the satellite cell response following exercise compared to RE alone.

Methods

Eight sedentary, overweight/obese, middle-aged individuals performed RE only (8 × 8 leg extensions at 70% 1RM), or RE + HIIT (10 × 1 min at 90% HR_max on a cycle ergometer). Muscle biopsies were collected from the vastus lateralis before and 96 h after the RE component to determine muscle fiber type-specific total (Pax7⁺ cells) and active (MyoD⁺ cells) satellite cell number using immunofluorescence microscopy.

Results

Type-I-specific Pax7⁺ (P = 0.001) cell number increased after both exercise trials. Type-I-specific MyoD⁺ (P = 0.001) cell number increased after RE only. However, an elevated baseline value in RE + HIIT compared to RE (P = 0.046) was observed, with no differences between exercise trials at 96 h (P = 0.21). Type-II-specific Pax7⁺ and MyoD⁺ cell number remained unchanged after both exercise trials (all P ≥ 0.13).

Conclusion

Combining a HIIT session after a single bout of RE does not interfere with the increase in type-I-specific total, and possibly active, satellite cell number, compared to RE only. Concurrent RE + HIIT may offer a time-efficient way to maximise the physiological benefits from a single bout of exercise in sedentary, overweight/obese, middle-aged individuals.

Alberti KGMM, Zimmet P, Shaw J (2005) The metabolic syndrome—a new worldwide definition. Lancet 366:1059–1062. doi:10.1016/S0140-6736(05)67402-8 CrossRefPubMed

Apró W, Wang L, Pontén M, Blomstrand E, Sahlin K (2013) Resistance exercise induced mTORC1 signaling is not impaired by subsequent endurance exercise in human skeletal muscle. Am J Physiol Endocrinol Metab 305:E22–E32. doi:10.1152/ajpendo.00091.2013 CrossRefPubMed

Babcock L, Escano M, D’Lugos A, Todd K, Murach K, Luden N (2012) Concurrent aerobic exercise interferes with the satellite cell response to acute resistance exercise. Am J Physiol Regul Integr Comp Physiol 302:R1458–R1465. doi:10.1152/ajpregu.00035.2012 CrossRefPubMed

Bartlett JD, Close GL, MacLaren DPM, Gregson W, Drust B, Morton JP (2011) High-intensity interval running is perceived to be more enjoyable than moderate-intensity continuous exercise: implications for exercise adherence. J Sports Sci 29:547–553. doi:10.1080/02640414.2010.545427 CrossRefPubMed

Bell GJ, Petersen SR, Wessel J, Bagnall K, Quinney HA (1991) Physiological adaptations to concurrent endurance training and low velocity resistance training. Int J Sports Med 12:384–390. doi:10.1055/s-2007-1024699 CrossRefPubMed

Bell KE, Séguin C, Parise G, Baker SK, Phillips SM (2015) Day-to-day changes in muscle protein synthesis in recovery from resistance, aerobic, and high-intensity interval exercise in older men. J Gerontol Ser A Biol Sci Med Sci 70:1024–1029. doi:10.1093/gerona/glu313 CrossRef

Bellamy LM, Joanisse S, Grubb A, Mitchell CJ, McKay BR, Phillips SM, Baker S, Parise G (2014) The acute satellite cell response and skeletal muscle hypertrophy following resistance training. PLoS One 9:e109739. doi:10.1371/journal.pone.0109739 CrossRefPubMedPubMedCentral

Bijlsma AY, Meskers CGM, Ling CHY, Narici M, Kurrle SE, Cameron ID, Westendorp RGJ, Maier AB (2013) Defining sarcopenia: the impact of different diagnostic criteria on the prevalence of sarcopenia in a large middle aged cohort. Age (Dordr) 35:871–881. doi:10.1007/s11357-012-9384-z CrossRef

Borg G (1998) Borg’s perceived exertion and pain scales. Human Kinetics, Champagin

Cassidy S, Thoma C, Hallsworth K, Parikh J, Hollingsworth KG, Taylor R, Jakovljevic DG, Trenell MI (2016) High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial. Diabetologia 59:56–66. doi:10.1007/s00125-015-3741-2 CrossRefPubMed

Cermak NM, Snijders T, McKay BR, Parise G, Verdijk LB, Tarnopolsky MA, Gibala MJ, van Loon LJC (2013) Eccentric exercise increases satellite cell content in type II muscle fibers. Med Sci Sport Exerc 45:230–237. doi:10.1249/MSS.0b013e318272cf47 CrossRef

Charifi N, Kadi F, Féasson L, Denis C (2003) Effects of endurance training on satellite cell frequency in skeletal muscle of old men. Muscle Nerve 28:87–92. doi:10.1002/mus.10394 CrossRefPubMed

Chief Medical Office (2011) Physical activity guidelines in the UK: review and recommendations

Coffey VG, Jemiolo B, Edge J, Garnham AP, Trappe SW, Hawley JA (2009a) Effect of consecutive repeated sprint and resistance exercise bouts on acute adaptive responses in human skeletal muscle. Am J Physiol Regul Integr Comp Physiol 297:R1441–R1451. doi:10.1152/ajpregu.00351.2009 CrossRefPubMed

Coffey VG, Pilegaard H, Garnham AP, O’Brien BJ, Hawley JA (2009b) Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscle. J Appl Physiol 106:1187–1197. doi:10.1152/japplphysiol.91221.2008 CrossRefPubMed

Craig B, Lucas J, Pohlman R, Stelling H (1991) The effects of running, weightlifting and a combination of both on growth hormone release. J Appl Sport Sci Res 5:198–203. doi:10.1519/00124278-199111000-00005

Crameri RM, Langberg H, Magnusson P, Jensen CH, Schrøder HD, Olesen JL, Suetta C, Teisner B, Kjaer M (2004) Changes in satellite cells in human skeletal muscle after a single bout of high intensity exercise. J Physiol 558:333–340. doi:10.1113/jphysiol.2004.061846 CrossRefPubMedPubMedCentral

Crameri RM, Aagaard P, Qvortrup K, Langberg H, Olesen J, Kjaer M (2007) Myofibre damage in human skeletal muscle: effects of electrical stimulation versus voluntary contraction. J Physiol 583:365–380. doi:10.1113/jphysiol.2007.128827 CrossRefPubMedPubMedCentral

Currie KD, Dubberley JB, McKelvie RS, Macdonald MJ (2013) Low-volume, high-intensity interval training in patients with CAD. Med Sci Sports Exerc 45:1436–1442. doi:10.1249/MSS.0b013e31828bbbd4 CrossRefPubMed

Dominguez LJ, Barbagallo M (2007) The cardiometabolic syndrome and sarcopenic obesity in older persons. J Cardiometab Syndr 2:183–189. doi:10.1111/j.1559-4564.2007.06673.x CrossRefPubMed

Donges CE, Burd NA, Duffield R, Smith GC, West DWD, Short MJ, Mackenzie R, Plank LD, Shepherd PR, Phillips SM, Edge JA (2012) Concurrent resistance and aerobic exercise stimulates both myofibrillar and mitochondrial protein synthesis in sedentary middle-aged men. J Appl Physiol 112:1992–2001. doi:10.1152/japplphysiol.00166.2012 CrossRefPubMed

Dreyer HC, Blanco CE, Sattler FR, Schroeder ET, Wiswell RA (2006) Satellite cell numbers in young and older men 24 h after eccentric exercise. Muscle Nerve 33:242–253. doi:10.1002/mus.20461 CrossRefPubMed

Faul F, Erdfelder E, Lang A-G, Buchner A (2007) G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39:175–191. doi:10.3758/BF03193146 CrossRefPubMed

Faulkner S, Pugh J, Hood T, Menon K, King J, Nimmo M (2015) Group studio cycling; an effective intervention to improve cardio-metabolic health in overweight physically inactive individuals. J Fit Res 4:16–25

Fry CS, Noehren B, Mula J, Ubele MF, Westgate PM, Kern PA, Peterson CA (2014) Fibre type-specific satellite cell response to aerobic training in sedentary adults. J Physiol 592:2625–2635. doi:10.1113/jphysiol.2014.271288 CrossRefPubMedPubMedCentral

Fyfe JJ, Bartlett JD, Hanson ED, Stepto NK, Bishop DJ (2016) Endurance training intensity does not mediate interference to maximal lower-body strength gain during short-term concurrent training. Front Physiol 7:1–16. doi:10.3389/fphys.2016.00487 CrossRef

Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee I-M, Nieman DC, Swain DP (2011) Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43:1334–1359. doi:10.1249/MSS.0b013e318213fefb CrossRefPubMed

Gibala MJ, Little JP, Macdonald MJ, Hawley JA (2012) Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol 590:1077–1084. doi:10.1113/jphysiol.2011.224725 CrossRefPubMedPubMedCentral

Gillen JB, Percival ME, Ludzki A, Tarnopolsky MA, Gibala MJ (2013) Interval training in the fed or fasted state improves body composition and muscle oxidative capacity in overweight women. Obesity 21:2249–2255. doi:10.1002/oby.20379 CrossRefPubMed

Hamilton DL, Philp A (2013) Can AMPK mediated suppression of mTORC1 explain the concurrent training effect? Cell Mol Exerc Physiol 2:1–27. doi:10.7457/cmep.v2i1.e4 CrossRef

Health and Social Care Information Centre (2013) Health survey for England, 2012—health, social care and lifestyles: summary of key findings. https://digital.nhs.uk. Accessed 8 Sep 2016

Health and Social Care Information Centre (2016) Statistics on obesity, physical activity and diet. https://digital.nhs.uk. Accessed 8 Sep 2016

Hennessy L, Watson A (1994) The interference effects of training for strength and endurance simultaneously. J Strength Cond Res 8:12–19. doi:10.1519/00124278-199402000-00003

Hickson RC (1980) Interference of strength development by simultaneously training for strength and endurance. Eur J Appl Physiol Occup Physiol 45:255–263CrossRefPubMed

Jackson AS, Janssen I, Sui X, Church TS, Blair SN (2012) Longitudinal changes in body composition associated with healthy ageing: men, aged 20–96 years. Br J Nutr 107:1085–1091. doi:10.1017/S0007114511003886 CrossRefPubMed

Kazior Z, Willis SJ, Moberg M, Apró W, Calbet JAL, Holmberg HC, Blomstrand E (2016) Endurance exercise enhances the effect of strength training on muscle fiber size and protein expression of akt and mTOR. PLoS One 11:1–18. doi:10.1371/journal.pone.0149082 CrossRef

Kemmler W, Lell M, Scharf M, Fraunberger L, von Stengel S (2015) High versus moderate intense running exercise—effects on cardiometabolic risk-factors in untrained males. Dtsch Med Wochenschr 140:e7–e13. doi:10.1055/s-0040-100423 CrossRefPubMed

Kikuchi N, Yoshida S, Okuyama M, Nakazato K (2016) The effect of high-intensity interval cycling sprints subsequent to arm-curl exercise on upper-body muscle strength and hypertrophy. J Strength Cond Res 30:2318–2323. doi:10.1519/JSC.0000000000001315 CrossRefPubMed

Kurosaka M, Naito H, Ogura Y, Machida S, Katamoto S (2012) Satellite cell pool enhancement in rat plantaris muscle by endurance training depends on intensity rather than duration. Acta Physiol (Oxf) 205:159–166. doi:10.1111/j.1748-1716.2011.02381.x CrossRef

Langley B, Thomas M, Bishop A, Sharma M, Gilmour S, Kambadur R (2002) Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J Biol Chem 277:49831–49840. doi:10.1074/jbc.M204291200 CrossRefPubMed

Larose J, Sigal RJ, Khandwala F, Kenny GP (2012) Comparison of strength development with resistance training and combined exercise training in type 2 diabetes. Scand J Med Sci Sports 22:e45–e54. doi:10.1111/j.1600-0838.2011.01412.x CrossRefPubMed

Louis E, Raue U, Yang Y, Jemiolo B, Trappe S (2007) Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle. J Appl Physiol 103:1744–1751. doi:10.1152/japplphysiol.00679.2007 CrossRefPubMed

Lundberg TR, Fernandez-Gonzalo R, Gustafsson T, Tesch PA (2012) Aerobic exercise alters skeletal muscle molecular responses to resistance exercise. Med Sci Sports Exerc 44:1680–1688. doi:10.1249/MSS.0b013e318256fbe8 CrossRefPubMed

Lundberg TR, Fernandez-Gonzalo R, Gustafsson T, Tesch PA (2013) Aerobic exercise does not compromise muscle hypertrophy response to short-term resistance training. J Appl Physiol 114:81–89. doi:10.1152/japplphysiol.01013.2012 CrossRefPubMed

Mackey AL, Kjaer M, Charifi N, Henriksson J, Bojsen-Moller J, Holm L, Kadi F (2009) Assessment of satellite cell number and activity status in human skeletal muscle biopsies. Muscle Nerve 40:455–465. doi:10.1002/mus.21369 CrossRefPubMed

Madsen SM, Thorup AC, Overgaard K, Jeppesen PB (2015) High intensity interval training improves glycaemic control and pancreatic β cell function of type 2 diabetes patients. PLoS One 10:e0133286. doi:10.1371/journal.pone.0133286 CrossRefPubMedPubMedCentral

Marcell TJ (2003) Sarcopenia: causes, consequences, and preventions. J Gerontol Med Sci 58:M911–M916. doi:10.1093/gerona/58.10.M911 CrossRef

Martin NR, Lewis MP (2012) Satellite cell activation and number following acute and chronic exercise: a mini review. Cell Mol Exerc Physiol 1:e3. doi:10.7457/cmep.v1i1.e3 CrossRef

McCroskery S, Thomas M, Maxwell L, Sharma M, Kambadur R (2003) Myostatin negatively regulates satellite cell activation and self-renewal. J Cell Biol 162:1135–1147. doi:10.1083/jcb.200207056 CrossRefPubMedPubMedCentral

McKay BR, O’Reilly CE, Phillips SM, Tarnopolsky MA, Parise G (2008) Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humans. J Physiol 586:5549–5560. doi:10.1113/jphysiol.2008.160176 CrossRefPubMedPubMedCentral

McKay BR, De Lisio M, Johnston APW, O’Reilly CE, Phillips SM, Tarnopolsky MA, Parise G (2009) Association of interleukin-6 signalling with the muscle stem cell response following muscle-lengthening contractions in humans. PLoS One 4:e6027. doi:10.1371/journal.pone.0006027 CrossRefPubMedPubMedCentral

McKay BR, Ogborn DI, Bellamy LM, Tarnopolsky MA, Parise G (2012) Myostatin is associated with age-related human muscle stem cell dysfunction. FASEB J 26:2509–2521. doi:10.1096/fj.11-198663 CrossRefPubMed

McPherron AC, Lee SJ (1997) Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci USA 94:12457–12461. doi:10.1073/pnas.94.23.12457 CrossRefPubMedPubMedCentral

Mikkelsen UR, Langberg H, Helmark IC, Skovgaard D, Andersen LL, Kjaer M, Mackey AL (2009) Local NSAID infusion inhibits satellite cell proliferation in human skeletal muscle after eccentric exercise. J Appl Physiol 107:1600–1611. doi:10.1152/japplphysiol.00707.2009 CrossRefPubMedPubMedCentral

Nederveen JP, Joanisse S, Séguin CML, Bell KE, Baker SK, Phillips SM, Parise G (2015) The effect of exercise mode on the acute response of satellite cells in old men. Acta Physiol (Oxf) 215:177–190. doi:10.1111/apha.12601 CrossRef

O’Reilly C, McKay B, Phillips S, Tarnopolsky M, Parise G (2008) Hepatocyte growth factor (HGF) and the satellite cell response following muscle lengthening contractions in humans. Muscle Nerve 38:1434–1442. doi:10.1002/mus.21146 CrossRefPubMed

Olesen J, Kiilerich K, Pilegaard H (2010) PGC-1alpha-mediated adaptations in skeletal muscle. Eur J Physiol 460:153–162. doi:10.1007/s00424-010-0834-0 CrossRef

Psilander N, Damsgaard R, Pilegaard H (2003) Resistance exercise alters MRF and IGF-I mRNA content in human skeletal muscle. J Appl Physiol 95:1038–1044. doi:10.1152/japplphysiol.00903.2002 CrossRefPubMed

Pugh JK, Faulkner SH, Jackson AP, King JA, Nimmo MA (2015) Acute molecular responses to concurrent resistance and high-intensity interval exercise in untrained skeletal muscle. Physiol Rep 3:e12364. doi:10.14814/phy2.12364 CrossRefPubMedPubMedCentral

Rana JS, Li TY, Manson JE, Hu FB (2007) Adiposity compared with physical inactivity and risk of type 2 diabetes in women. Diabetes Care 30:53–58. doi:10.2337/dc06-1456 CrossRefPubMed

Reddigan JI, Ardern CI, Riddell MC, Kuk JL (2011) Relation of physical activity to cardiovascular disease mortality and the influence of cardiometabolic risk factors. Am J Cardiol 108:1426–1431. doi:10.1016/j.amjcard.2011.07.005 CrossRefPubMed

Reisz-Porszasz S, Bhasin S, Artaza JN, Shen R, Sinha-Hikim I, Hogue A, Fielder TJ, Gonzalez-Cadavid NF (2003) Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin. Am J Physiol Endocrinol Metab 285:E876–E888. doi:10.1152/ajpendo.00107.2003 CrossRefPubMed

Schneider CA, Rasband WS, Eliceiri KW (2012) NIH Image to ImageJ: 25 years of image analysis. Nat Methods 9:671–675. doi:10.1038/nmeth.2089 CrossRefPubMedPubMedCentral

Shaw BS, Shaw I, Brown GA (2009) Comparison of resistance and concurrent resistance and endurance training regimes in the development of strength. J Strength Cond Res 23:2507–2514. doi:10.1519/JSC.0b013e3181bc191e CrossRefPubMed

Snijders T, Verdijk LB, Hansen D, Dendale P, van Loon LJC (2011) Continuous endurance-type exercise training does not modulate satellite cell content in obese type 2 diabetes patients. Muscle Nerve 43:393–401. doi:10.1002/mus.21891 CrossRefPubMed

Snijders T, Verdijk LB, Beelen M, McKay BR, Parise G, Kadi F, van Loon LJC (2012) A single bout of exercise activates skeletal muscle satellite cells during subsequent overnight recovery. Exp Physiol 97:762–773. doi:10.1113/expphysiol.2011.063313 CrossRefPubMed

Snijders T, Verdijk LB, Smeets JSJ, McKay BR, Senden JMG, Hartgens F, Parise G, Greenhaff P, van Loon LJC (2014) The skeletal muscle satellite cell response to a single bout of resistance-type exercise is delayed with aging in men. Age (Dordr) 36:9699. doi:10.1007/s11357-014-9699-z CrossRef

Snijders T, Nederveen JP, McKay BR, Joanisse S, Verdijk LB, van Loon LJC, Parise G (2015) Satellite cells in human skeletal muscle plasticity. Front Physiol 6:1–21. doi:10.3389/fphys.2015.00283 CrossRef

Stenholm S, Harris T, Rantenen T, Visser M, Kritchevsky SB, Ferrucci L (2008) Sarcopenic obesity-definition,etiology and consequences. Curr Opin Clin Nutr Metab Care 11:693–700. doi:10.1097/MCO.0b013e328312c37d.Sarcopenic CrossRefPubMedPubMedCentral

Stutts WC (2002) Physical activity determinants in adults. Perceived benefits, barriers, and self efficacy. AAOHN J 50:499–507. doi:10.1177/216507990205001106 PubMed

Terada T, Friesen A, Chahal BS, Bell GJ, McCargar LJ, Boulé NG (2013) Feasibility and preliminary efficacy of high intensity interval training in type 2 diabetes. Diabetes Res Clin Pract 99:120–129. doi:10.1016/j.diabres.2012.10.019 CrossRefPubMed

Tjønna AE, Lee SJ, Rognmo Ø, Stølen TO, Bye A, Haram PM, Loennechen JP, Al-Share QY, Skogvoll E, Slørdahl SA, Kemi OJ, Najjar SM, Wisløff U (2008) Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot study. Circulation 118:346–354. doi:10.1161/CIRCULATIONAHA.108.772822 CrossRefPubMedPubMedCentral

Trapp EG, Chisholm DJ, Freund J, Boutcher SH (2008) The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women. Int J Obes (Lond) 32:684–691. doi:10.1038/sj.ijo.0803781 CrossRef

Trost SG, Owen N, Bauman AE, Sallis JF, Brown W (2002) Correlates of adults’ participation in physical activity: review and update. Med Sci Sports Exerc 34:1996–2001. doi:10.1249/01.MSS.0000038974.76900.92 CrossRefPubMed

Verney J, Kadi F, Charifi N, Féasson L, Saafi MA, Castells J, Piehl-Aulin K, Denis C (2008) Effects of combined lower body endurance and upper body resistance training on the satellite cell pool in elderly subjects. Muscle Nerve 38:1147–1154. doi:10.1002/mus.21054 CrossRefPubMed

Welle S, Burgess K, Mehta S (2009) Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice. Am J Physiol Endocrinol Metab 296:E567–E572. doi:10.1152/ajpendo.90862.2008 CrossRefPubMedPubMedCentral

Yang Y, Creer A, Jemiolo B, Trappe S (2005) Time course of myogenic and metabolic gene expression in response to acute exercise in human skeletal muscle. J Appl Physiol 98:1745–1752. doi:10.1152/japplphysiol.01185.2004 CrossRefPubMed

Zammit PS, Golding JP, Nagata Y, Hudon V, Partridge TA, Beauchamp JR (2004) Muscle satellite cells adopt divergent fates: a mechanism for self-renewal? J Cell Biol 166:347–357. doi:10.1083/jcb.200312007 CrossRefPubMedPubMedCentral

Titel: Satellite cell response to concurrent resistance exercise and high-intensity interval training in sedentary, overweight/obese, middle-aged individuals
verfasst von: Jamie K. Pugh
Steve H. Faulkner
Mark C. Turner
Myra A. Nimmo
Publikationsdatum: 25.10.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Applied Physiology / Ausgabe 2/2018
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-017-3721-y

Neu im Fachgebiet Arbeitsmedizin

Das Geschlechterparadoxon in der gesundheitlich beeinträchtigten Lebenszeit – Ende eines Mythos?

Open Access Hüftgelenksbewegungseinschränkung Leitthema

Beginnend mit den 1920er-Jahren hat sich eine Vorstellung über die Geschlechterdifferenzen in Gesundheit und Mortalität etabliert, die von Lorber und Moore in dem einprägsamen Satz: „Women get sicker, but men die quicker“, zusammengefasst wurde [ 1 …, S. 13]. Tatsächlich erscheinen vor dem Hintergrund der höheren Lebenserwartung der Frauen die Studienergebnisse zu den Geschlechterdifferenzen in der Morbidität überraschend, wonach Frauen im Durchschnitt einen schlechteren Gesundheitszustand aufweisen als Männer [

Gesunde Lebenserwartung: Ein kritischer Blick auf Nutzen und Potenziale des demographischen Gesundheitsindikators

Open Access Leitthema

Die demographische Alterung hat vielfältige gesellschaftliche Konsequenzen, deren Ausmaß wesentlich vom Gesundheitszustand der Bevölkerung abhängt. Um diesen analysieren und bewerten zu können, wurden spezielle Kennziffern entwickelt, die in …

Wie hat sich die Lebenserwartung ohne funktionelle Einschränkungen in Deutschland entwickelt? Eine Analyse mit Daten des Deutschen Alterssurveys (DEAS)

Open Access Hüftgelenksbewegungseinschränkung Leitthema

Deutschland erfährt, wie andere Hocheinkommensstaaten, aufgrund kontinuierlich rückläufiger Mortalität und niedriger Geburtenraten tiefgreifende demografische Veränderungen. Der demografische Wandel führt in Deutschland zu einem zunehmend höheren …

Hitzeschutz im Fokus der hessischen Betreuungs- und Pflegeaufsicht

Open Access Klimawandel Übersichtsartikel

Im Sommer 2023 kündigte das Bundesministerium für Gesundheit (BMG) einen nationalen Hitzeschutzplan an und forderte die Länder auf, zu prüfen, „ob die Warnstufen des [Deutschen Wetterdienstes] DWD mit der Durchführung von Akutmaßnahmen …

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Satellite cell response to concurrent resistance exercise and high-intensity interval training in sedentary, overweight/obese, middle-aged individuals

Abstract

Purpose

Methods

Results

Conclusion

Neu im Fachgebiet Arbeitsmedizin

Das Geschlechterparadoxon in der gesundheitlich beeinträchtigten Lebenszeit – Ende eines Mythos?

Gesunde Lebenserwartung: Ein kritischer Blick auf Nutzen und Potenziale des demographischen Gesundheitsindikators

Wie hat sich die Lebenserwartung ohne funktionelle Einschränkungen in Deutschland entwickelt? Eine Analyse mit Daten des Deutschen Alterssurveys (DEAS)

Hitzeschutz im Fokus der hessischen Betreuungs- und Pflegeaufsicht

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2018

The impact of exertional-heat stress on gastrointestinal integrity, gastrointestinal symptoms, systemic endotoxin and cytokine profile

The availability of water associated with glycogen during dehydration: a reservoir or raindrop?

Non-invasive estimation of muscle oxygen uptake kinetics with pseudorandom binary sequence and step exercise responses

Selective effects of different fatigue protocols on the function of upper body muscles assessed through the force–velocity relationship

Blood flow restriction late in recovery after heavy resistance exercise hampers muscle recuperation

Short vs. long pulses for testing knee extensor neuromuscular properties: does it matter?

Neu im Fachgebiet Arbeitsmedizin

Das Geschlechterparadoxon in der gesundheitlich beeinträchtigten Lebenszeit – Ende eines Mythos?

Gesunde Lebenserwartung: Ein kritischer Blick auf Nutzen und Potenziale des demographischen Gesundheitsindikators

Wie hat sich die Lebenserwartung ohne funktionelle Einschränkungen in Deutschland entwickelt? Eine Analyse mit Daten des Deutschen Alterssurveys (DEAS)

Hitzeschutz im Fokus der hessischen Betreuungs- und Pflegeaufsicht