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01.02.2010 | Original Research Paper

sTNFR-1 is an early inflammatory marker in community versus institutionalized elderly women

verfasst von: Fernanda Matos Coelho, F. M. S. Narciso, D. M. G. Oliveira, D. S. Pereira, A. L. Teixeira, M. M. Teixeira, D. G. Souza, L. S. M. Pereira

Erschienen in: Inflammation Research | Ausgabe 2/2010

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Abstract

Objective and design

To evaluate plasma sTNFR-1 and IL-6 levels and correlate with hand grip in the institutionalized and community living Brazilian elderly.

Material

A convenience sample of 110 elderly women (71.17 ± 7.44 years) was selected. Plasma sTNFR-1 and IL-6 levels were measured by ELISA. For the measurement of hand grip, a JAMAR dynamometer was used.

Results

Plasma concentrations of inflammatory markers were significantly higher in institutionalized elderly (sTNFR-1: 479 ± 22 pg/mL; IL-6: 6.3 ± 0.8 pg/mL) than in community-dwelling elderly (sTNFR-1: 329 ± 24 pg/mL; IL-6: 2.5 ± 0.4 pg/mL; P < 0.0001). Institutionalized elderly had reduced hand grip (15 ± 0.8 Kgf) in comparison to community dwelling elderly (23 ± 0.6 Kgf; P < 0.05). When individuals were subdivided in age groups, sTNFR-1 was higher in community dwelling versus institutionalized elderly in the 60–70 age range.

Conclusions

Our results demonstrate that being institutionalized has an impact on levels of inflammatory markers.

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Titel: sTNFR-1 is an early inflammatory marker in community versus institutionalized elderly women
verfasst von: Fernanda Matos Coelho
F. M. S. Narciso
D. M. G. Oliveira
D. S. Pereira
A. L. Teixeira
M. M. Teixeira
D. G. Souza
L. S. M. Pereira
Publikationsdatum: 01.02.2010
Verlag: SP Birkhäuser Verlag Basel
Erschienen in: Inflammation Research / Ausgabe 2/2010
Print ISSN: 1023-3830
Elektronische ISSN: 1420-908X
DOI: https://doi.org/10.1007/s00011-009-0079-6

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Abstract

Objective and design

Material

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Conclusions

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