Background
Objectives
Methods
Search strategy
Search # | Search query |
---|---|
1 | Integrat* OR joint OR collaborat* OR concurrent OR concomitant |
2 | Treat* OR therap* OR care OR service OR manag* |
3 | ‘Human immun?deficiency virus’ OR HIV OR HIV1 OR HIV2 OR AIDS OR ‘Acquired immune?deficiency syndrome’ OR anti?retroviral |
4 | Tuberculosis OR ‘Mycobacterium tuberculosis’ OR ‘Pulmonary tuberculosis’ OR TB OR anti?tubercul* |
5 | #1 AND #2 AND #3 AND #4 |
Selection criteria
Item | Inclusion criteria | Exclusion criteria |
---|---|---|
Population | Studies involving adults who are co-infected with MDR-TB and HIV in LMICs | Studies involving -Pregnant women -Patients with multi-morbidities |
Intervention | Studies reporting on the delivery of integrated treatment of TB and HIV in LMICs | -Studies describing treatment of only MDR-TB -Studies describing integrated treatment of drug-sensitive TB and HIV -Studies describing integrated treatment of more than 2 diseases (TB/HIV) |
Comparison | ||
Outcome(s) | Studies reporting on MDR-TB outcomes and/or their predictors in the setting of integrated therapy for TB/HIV. | Studies describing outcomes that are unrelated to treatment of MDR-TB in the context of integrated TB/HIV therapy |
Study design | Observational studies specifically, cohort studies that use quantitative research methods | 1) Interventional studies 2) Observational studies other than cohort, e.g. cross-sectional studies 3) Mini-reviews, conference abstracts, letters to editors, editorials, commentaries. 4) Studies whose full data will not be available even upon requesting from the author 5) Duplicates studies: for studies published with the same or different titles or in more than one journal, the most updated version shall be considered. |