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Erschienen in: Lasers in Medical Science 9/2022

10.08.2022 | Original Article

The effects of photobiomodulation therapy in individuals with tinnitus and without hearing loss

verfasst von: Mirele Regina Silva, Amanda Rodrigues Scheffer, Roberto Sávio de Assunção Bastos, Maria Cristina Chavantes, Maria Fernanda Capoani Garcia Mondelli

Erschienen in: Lasers in Medical Science | Ausgabe 9/2022

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Abstract

To verify the effect of photobiomodulation therapy (PBMT) in individuals with chronic tinnitus without hearing loss, 20 patients who met the inclusion criteria were randomly divided into group 1: active low-level laser (LLL) and group 2: equipment without laser (placebo). Upon anamnesis, data collection, and audiological exams, the Tinnitus Handicap Inventory (THI) and the Visual-Analog Scale (EVA) were applied to measure the level of discomfort with tinnitus and the level of discomfort before and after laser treatment. The protocol used included 12 active LLL sessions for group 1 and not active for group 2, varying red and infrared wavelengths. There was a reduction in the disadvantage of individuals with tinnitus after the intervention and between the initial and final sessions, regardless of the intervention, although group 1 showed a greater reduction than group 2, regardless of point in time of assessment and number of session. There was no statistical difference as to group and point in time for the high-frequency audiometry and acuphenometry outcomes. Individuals with chronic tinnitus reduced the complaint, regardless of point in time and group of intervention; however, the group that received PBMT improved the level of satisfaction, regardless of point in time of assessment and number of session.
Literatur
1.
Zurück zum Zitat Mowafy ZME, Alsayed ARS, Hassan MESM (2016) Effect of Low Intensity Laser on Severe Tinnitus in Idiopathic Sudden Hearing Loss Patients. Int J Med Health Sci 3(6):1–6 Mowafy ZME, Alsayed ARS, Hassan MESM (2016) Effect of Low Intensity Laser on Severe Tinnitus in Idiopathic Sudden Hearing Loss Patients. Int J Med Health Sci 3(6):1–6
2.
Zurück zum Zitat Ngao CF, Tan TS, Narayanan RR (2013) The effectiveness of transmeatal low-power laser stimulation in treating tinnitus. Eur ArchOtorhinolaryngol 271(5):975–980CrossRef Ngao CF, Tan TS, Narayanan RR (2013) The effectiveness of transmeatal low-power laser stimulation in treating tinnitus. Eur ArchOtorhinolaryngol 271(5):975–980CrossRef
3.
Zurück zum Zitat Oostendorp RAB, Bakker I, Elvers H, Mikolajewska E, Michiels S, De Hertogh W et al (2016) Cervicogenic somatosensory tinnitus: an indication for manual therapy? Part 1. Man Ther 23:120–123PubMedCrossRef Oostendorp RAB, Bakker I, Elvers H, Mikolajewska E, Michiels S, De Hertogh W et al (2016) Cervicogenic somatosensory tinnitus: an indication for manual therapy? Part 1. Man Ther 23:120–123PubMedCrossRef
4.
Zurück zum Zitat Sanchez TG, Medeiros IRT, Levy CPD, Ramalho JRO, Bento RF (2005) Tinnitus in normally hearing patients: clinical aspects and repercussions. Rev Bras Otorrinolaringol 71(4):427–431CrossRef Sanchez TG, Medeiros IRT, Levy CPD, Ramalho JRO, Bento RF (2005) Tinnitus in normally hearing patients: clinical aspects and repercussions. Rev Bras Otorrinolaringol 71(4):427–431CrossRef
5.
Zurück zum Zitat Oiticica J, Bittar RS (2015) Tinnitus prevalence in the city of São Paulo. Braz J Otorhinolaryngol 81(2):167–176PubMedCrossRef Oiticica J, Bittar RS (2015) Tinnitus prevalence in the city of São Paulo. Braz J Otorhinolaryngol 81(2):167–176PubMedCrossRef
6.
Zurück zum Zitat Suzuki FAB, Suzuki FA, Onishi ET, Penido NO (2018) Psychoacoustic classification of persistent tinnitus. Braz J Otorhinolaryngol 84(5):583–590PubMedCrossRef Suzuki FAB, Suzuki FA, Onishi ET, Penido NO (2018) Psychoacoustic classification of persistent tinnitus. Braz J Otorhinolaryngol 84(5):583–590PubMedCrossRef
7.
Zurück zum Zitat Dobie RA (2004) Overview: suffering from tinnitus. In: Snow JB. Tinnitus: theory and management cap. 1, p. 1–7. Shelton: PMPH-USA Dobie RA (2004) Overview: suffering from tinnitus. In: Snow JB. Tinnitus: theory and management cap. 1, p. 1–7. Shelton: PMPH-USA
8.
Zurück zum Zitat Tunkel DE, Bauer CA, Sun GH, Rosenfeld RM, Chandrasekhar SS, Cunningham ER et al (2014) Clinical Practice Guideline: tinnitus. Otolaryngol Head Neck Surg 151(2):1–40CrossRef Tunkel DE, Bauer CA, Sun GH, Rosenfeld RM, Chandrasekhar SS, Cunningham ER et al (2014) Clinical Practice Guideline: tinnitus. Otolaryngol Head Neck Surg 151(2):1–40CrossRef
9.
Zurück zum Zitat Santos AS (2016) Avaliação dos ensaios clínicos homeopáticos quanto a sua eficácia no tratamento de pacientes com zumbido. Monografia, Escola Baiana de Medicina e Saúde Pública. Santos AS (2016) Avaliação dos ensaios clínicos homeopáticos quanto a sua eficácia no tratamento de pacientes com zumbido. Monografia, Escola Baiana de Medicina e Saúde Pública.
10.
Zurück zum Zitat Montazeri K, Mahmoudian S, Razaghi Z, Farhadi M (2017) Alterations in auditory electrophysiological responses associated with temporary suppression of tinnitus induced by low-level laser therapy: a before-after case series. J Lasers Med Sci 8(1):38–45CrossRef Montazeri K, Mahmoudian S, Razaghi Z, Farhadi M (2017) Alterations in auditory electrophysiological responses associated with temporary suppression of tinnitus induced by low-level laser therapy: a before-after case series. J Lasers Med Sci 8(1):38–45CrossRef
11.
Zurück zum Zitat Henry JA, Roberts LE, Caspary DM, Theodoroff SM, Salvi RJ (2014) Underlying mechanisms of tinnitus: review and clinical implications. J Am Acad Audiol 25(1):5–22PubMedPubMedCentralCrossRef Henry JA, Roberts LE, Caspary DM, Theodoroff SM, Salvi RJ (2014) Underlying mechanisms of tinnitus: review and clinical implications. J Am Acad Audiol 25(1):5–22PubMedPubMedCentralCrossRef
12.
Zurück zum Zitat Rochkind S, Nissan M, Lubart R, Avran J, Bartal A (1988) The in-vivo-nerve response to direct low-energy-laser irradiation. Acta Neurochir 94(1–2):74–77PubMedCrossRef Rochkind S, Nissan M, Lubart R, Avran J, Bartal A (1988) The in-vivo-nerve response to direct low-energy-laser irradiation. Acta Neurochir 94(1–2):74–77PubMedCrossRef
13.
Zurück zum Zitat Shiomi Y, Takahashi H, Honjo I, Kojima H, Naito Y, Fujiki N (1997) Efficacy of transmeatal low power laser irradiation on tinnitus: a preliminary report. Auris Nasus Larynx 24(1):39–42PubMedCrossRef Shiomi Y, Takahashi H, Honjo I, Kojima H, Naito Y, Fujiki N (1997) Efficacy of transmeatal low power laser irradiation on tinnitus: a preliminary report. Auris Nasus Larynx 24(1):39–42PubMedCrossRef
14.
Zurück zum Zitat Schaffer M, Bone H, Sroka R, Schaffer PM, Reiser M, Dühmke E (2000) Effects of 780 nm diode laser irradiation on blood microcirculation: preliminary findings on time-dependent T1-weighted contrast-enhanced magnetic resonance imaging (MRI). J Photochem Photobiol B 54(1):55–60PubMedCrossRef Schaffer M, Bone H, Sroka R, Schaffer PM, Reiser M, Dühmke E (2000) Effects of 780 nm diode laser irradiation on blood microcirculation: preliminary findings on time-dependent T1-weighted contrast-enhanced magnetic resonance imaging (MRI). J Photochem Photobiol B 54(1):55–60PubMedCrossRef
15.
Zurück zum Zitat Farivar S, Malekshahabi T, Shiari R (2014) Biological effects of low-level laser therapy. J Lasers Med Sci 5(2):58–62PubMedPubMedCentral Farivar S, Malekshahabi T, Shiari R (2014) Biological effects of low-level laser therapy. J Lasers Med Sci 5(2):58–62PubMedPubMedCentral
16.
Zurück zum Zitat Spanemberg JC, Figueiredo MA, Cherubini K, Salun FG (2016) Low-level laser therapy: a review of its applications in the management of oral mucosal disorders. Altern Ther Health Med 22(6):24–30PubMed Spanemberg JC, Figueiredo MA, Cherubini K, Salun FG (2016) Low-level laser therapy: a review of its applications in the management of oral mucosal disorders. Altern Ther Health Med 22(6):24–30PubMed
17.
Zurück zum Zitat Pacheco JA, Schapochnik A (2018) Fotobiomodulação, com laser de baixa intensidade, fotobiomodulação, nos músculos mastigatórios masseter e temporal para tratamento de bruxismo. Rev Cient Mult Núcl Conhecim 7(9):114–120 Pacheco JA, Schapochnik A (2018) Fotobiomodulação, com laser de baixa intensidade, fotobiomodulação, nos músculos mastigatórios masseter e temporal para tratamento de bruxismo. Rev Cient Mult Núcl Conhecim 7(9):114–120
18.
Zurück zum Zitat Estrela JV, Duarte CCF, Almeida DNA, Araruna VR, Silva RMV, Cavalcanti RL et al (2014) Efeito do led na flacidez tissular facial. Rev Catussaba 3(2):29–36 Estrela JV, Duarte CCF, Almeida DNA, Araruna VR, Silva RMV, Cavalcanti RL et al (2014) Efeito do led na flacidez tissular facial. Rev Catussaba 3(2):29–36
19.
Zurück zum Zitat Tenis CA, Martins MD, Gonçalves MLL, Silva DFTD, Cunha Filho JJD, Martins MAT et al (2018) Efficacy of light-emitting diode (LED) photobiomodulation in pain management, facial edema, trismus, and quality of life after extraction of retained lower third molars. Medicine 97(37):1–6CrossRef Tenis CA, Martins MD, Gonçalves MLL, Silva DFTD, Cunha Filho JJD, Martins MAT et al (2018) Efficacy of light-emitting diode (LED) photobiomodulation in pain management, facial edema, trismus, and quality of life after extraction of retained lower third molars. Medicine 97(37):1–6CrossRef
20.
Zurück zum Zitat Poloni MM, Marques NP, Ribeiro Junior NV, Sperandio FF, Hanemann JAC, de Carli ML (2018) Bell’s palsy treated with photobiomodulation in an adolescent: Rare case report and review of the published literature. Int J Paediatr Dent 28(6):658–662PubMedCrossRef Poloni MM, Marques NP, Ribeiro Junior NV, Sperandio FF, Hanemann JAC, de Carli ML (2018) Bell’s palsy treated with photobiomodulation in an adolescent: Rare case report and review of the published literature. Int J Paediatr Dent 28(6):658–662PubMedCrossRef
21.
Zurück zum Zitat Hamblin MR (2016) Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophys 4(3):337–361CrossRef Hamblin MR (2016) Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophys 4(3):337–361CrossRef
23.
Zurück zum Zitat Mirz F, Zachariae R, Andersen SE, Nielsen AG, Johansen LV, Bjerring P et al (1999) The low-power laser in the treatment of tinnitus. Clin Otolaryngol Allied Sci 24(4):346–354PubMedCrossRef Mirz F, Zachariae R, Andersen SE, Nielsen AG, Johansen LV, Bjerring P et al (1999) The low-power laser in the treatment of tinnitus. Clin Otolaryngol Allied Sci 24(4):346–354PubMedCrossRef
24.
Zurück zum Zitat Teggi R, Bellini C, Piccioni LO, Bussi M (2009) Transmeatal low-level laser therapy for chronic tinnitus with cochlear dysfunction. Audiol Neurotol 14(2):115–120CrossRef Teggi R, Bellini C, Piccioni LO, Bussi M (2009) Transmeatal low-level laser therapy for chronic tinnitus with cochlear dysfunction. Audiol Neurotol 14(2):115–120CrossRef
25.
Zurück zum Zitat Mollasadeghi A, Mirmohammadi SJ, Mehrparvar AH, Davari MH, Shokouh P, Mostaghaci M et al (2013) Efficacy of low-level laser therapy in the management of tinnitus due to noise-induced hearing loss: a double-blind randomized clinical trial. Scientific World J 28(2013):1–7CrossRef Mollasadeghi A, Mirmohammadi SJ, Mehrparvar AH, Davari MH, Shokouh P, Mostaghaci M et al (2013) Efficacy of low-level laser therapy in the management of tinnitus due to noise-induced hearing loss: a double-blind randomized clinical trial. Scientific World J 28(2013):1–7CrossRef
26.
Zurück zum Zitat Tamura A, Matsunobu T, Mizutari K, Niwa T, Kawauchi S, Satoh S et al (2015) Low-level laser therapy for prevention of noise-induced hearing loss in rats. Neurosci Lett 19(595):81–86CrossRef Tamura A, Matsunobu T, Mizutari K, Niwa T, Kawauchi S, Satoh S et al (2015) Low-level laser therapy for prevention of noise-induced hearing loss in rats. Neurosci Lett 19(595):81–86CrossRef
27.
Zurück zum Zitat Peng Z, Chen XQ, Gong SS, Chen CF (2012) Low-level laser therapy for tinnitus. Cochrane DB Syst Rev 1–15 Peng Z, Chen XQ, Gong SS, Chen CF (2012) Low-level laser therapy for tinnitus. Cochrane DB Syst Rev 1–15
28.
Zurück zum Zitat Tauber S, Baumgartner R, Schorn K, Beyer W (2000) Lightdosimetric quantitative analysis of the human petrous bone: experimental study for laser irradiation of the cochlea. Lasers Surg Med 28(1):18–26CrossRef Tauber S, Baumgartner R, Schorn K, Beyer W (2000) Lightdosimetric quantitative analysis of the human petrous bone: experimental study for laser irradiation of the cochlea. Lasers Surg Med 28(1):18–26CrossRef
29.
Zurück zum Zitat Tauber S, Schorn K, Beyer W, Baumgartner R (2003) Transmeatal cochlear laser (TCL) treatment of cochlear dysfunction: A feasibility study for chronic tinnitus. Lasers Med Sci 18(3):154–161PubMedCrossRef Tauber S, Schorn K, Beyer W, Baumgartner R (2003) Transmeatal cochlear laser (TCL) treatment of cochlear dysfunction: A feasibility study for chronic tinnitus. Lasers Med Sci 18(3):154–161PubMedCrossRef
30.
Zurück zum Zitat Procházková K, Sejna I, Schalek P, Rosina J, Hahn A (2015) A Combination of EGb 761 and soft laser therapy in chronic tinnitus. Update Hear Loss 1–9 Procházková K, Sejna I, Schalek P, Rosina J, Hahn A (2015) A Combination of EGb 761 and soft laser therapy in chronic tinnitus. Update Hear Loss 1–9
31.
Zurück zum Zitat Ferreira MC, De Matos IL, De Toledo IP, Honório HM, Mondelli MFCG (2021) Effects of Low-Level Laser Therapy as a Therapeutic Strategy for Patients With Tinnitus: A Systematic Review. J Speech Lang Hear Res 64:279–298PubMedCrossRef Ferreira MC, De Matos IL, De Toledo IP, Honório HM, Mondelli MFCG (2021) Effects of Low-Level Laser Therapy as a Therapeutic Strategy for Patients With Tinnitus: A Systematic Review. J Speech Lang Hear Res 64:279–298PubMedCrossRef
33.
Zurück zum Zitat Ferreira PEA, Cunha F, Onishi ET, Branco-Barreiro FCA, Ganança FF (2005) Tinnitus handicap inventory: cross-cultural adaptation to Brazilian Portuguese. Pro-Fono R Atual Cient 17(3):303–310CrossRef Ferreira PEA, Cunha F, Onishi ET, Branco-Barreiro FCA, Ganança FF (2005) Tinnitus handicap inventory: cross-cultural adaptation to Brazilian Portuguese. Pro-Fono R Atual Cient 17(3):303–310CrossRef
34.
Zurück zum Zitat Dehkordi MA, Einolghozati S, Ghasemi SM, Abolbashari S, Meshkat M, Behzad H (2015) Effect of low-level laser therapy in the treatment of cochlear tinnitus: a double-blind, placebo-controlled study. Ear Nose Throat J 94(1):32–36PubMed Dehkordi MA, Einolghozati S, Ghasemi SM, Abolbashari S, Meshkat M, Behzad H (2015) Effect of low-level laser therapy in the treatment of cochlear tinnitus: a double-blind, placebo-controlled study. Ear Nose Throat J 94(1):32–36PubMed
35.
Zurück zum Zitat Scheffer AR, Mondelli MFCG (2020) Tinnitus and Hearing Survey: adaptação cultural para o Português Brasileiro. Braz J Otorhinolaryngol in press Scheffer AR, Mondelli MFCG (2020) Tinnitus and Hearing Survey: adaptação cultural para o Português Brasileiro. Braz J Otorhinolaryngol in press
37.
Zurück zum Zitat Stohler NA, Reinau D, Jick SS, Bodmer D, Meier CR (2019) A study on the epidemiology of tinnitus in the United Kingdom. Clin Epidemiol 11:855–871PubMedPubMedCentralCrossRef Stohler NA, Reinau D, Jick SS, Bodmer D, Meier CR (2019) A study on the epidemiology of tinnitus in the United Kingdom. Clin Epidemiol 11:855–871PubMedPubMedCentralCrossRef
38.
Zurück zum Zitat Goodman SS, Bentler RA, Dittberner A, Mertes IB (2013) The effect of low-level laser therapy on hearing. ISRN Otolaryngol 2013:1–9CrossRef Goodman SS, Bentler RA, Dittberner A, Mertes IB (2013) The effect of low-level laser therapy on hearing. ISRN Otolaryngol 2013:1–9CrossRef
39.
Zurück zum Zitat Moon T, Lee MY, Jung JY, Chang SY, Chung PS, Rhee CK et al (2016) Safety assessment of trans-tympanic photobiomodulation. Lasers Med Sci 31(2):323–333PubMedCrossRef Moon T, Lee MY, Jung JY, Chang SY, Chung PS, Rhee CK et al (2016) Safety assessment of trans-tympanic photobiomodulation. Lasers Med Sci 31(2):323–333PubMedCrossRef
40.
Zurück zum Zitat Okhovat A, Berjis N, Okhovat H, Malekpour A, Abtahi H (2011) Low-level laser for treatment of tinnitus: a self-controlled clinical trial. J Res Med Sci 16(1):33–8PubMedPubMedCentral Okhovat A, Berjis N, Okhovat H, Malekpour A, Abtahi H (2011) Low-level laser for treatment of tinnitus: a self-controlled clinical trial. J Res Med Sci 16(1):33–8PubMedPubMedCentral
41.
Zurück zum Zitat Chang SY, Lee MY, Chung PS, Kim S, Choi B, Suh MW et al (2019) Enhanced mitochondrial membrane potential and ATP synthesis by photobiomodulation increases viability of the auditory cell line after gentamicin-induced intrinsic apoptosis. Nature 9:19248 Chang SY, Lee MY, Chung PS, Kim S, Choi B, Suh MW et al (2019) Enhanced mitochondrial membrane potential and ATP synthesis by photobiomodulation increases viability of the auditory cell line after gentamicin-induced intrinsic apoptosis. Nature 9:19248
43.
Zurück zum Zitat Chavantes MC (2009) Laser em Bio-medicina: princípios e prática. Atheneu, São Paulo, p 281 Chavantes MC (2009) Laser em Bio-medicina: princípios e prática. Atheneu, São Paulo, p 281
44.
Zurück zum Zitat Ailioaie LM, Litscher G, Webwe M, Ailoaie C, Litscher D, Chiran DA (2014) Innovations and challenges by applying sublingual laser blood irradiation in juvenile idiopathic arthritis. Int J Photoenergy 2014:1–8CrossRef Ailioaie LM, Litscher G, Webwe M, Ailoaie C, Litscher D, Chiran DA (2014) Innovations and challenges by applying sublingual laser blood irradiation in juvenile idiopathic arthritis. Int J Photoenergy 2014:1–8CrossRef
45.
Zurück zum Zitat Silva T, Silva FC, Gomes AO, Viana AO, Gonçalves MLL, Rodrigues MFSD et al (2018) Effect of photobiomodulation treatment in the sublingual, radial artery region, and along the spinal column in individuals with multiple sclerosis. Medicine 97(19):1–4CrossRef Silva T, Silva FC, Gomes AO, Viana AO, Gonçalves MLL, Rodrigues MFSD et al (2018) Effect of photobiomodulation treatment in the sublingual, radial artery region, and along the spinal column in individuals with multiple sclerosis. Medicine 97(19):1–4CrossRef
46.
Zurück zum Zitat Salahaldin AH, Abdulhadi K, Bener A (2012) Low-level laser therapy in patients with complaints of tinnitus: a clinical study. ISRN Otolaryngol 2012:1–5CrossRef Salahaldin AH, Abdulhadi K, Bener A (2012) Low-level laser therapy in patients with complaints of tinnitus: a clinical study. ISRN Otolaryngol 2012:1–5CrossRef
47.
Zurück zum Zitat Oppitz SJ, Silva LCL, Garcia MV, Silveira AF (2018) Limiares de audibilidade de altas frequências em indivíduos adultos normo-ouvintes. CoDAS 30(4):1–7CrossRef Oppitz SJ, Silva LCL, Garcia MV, Silveira AF (2018) Limiares de audibilidade de altas frequências em indivíduos adultos normo-ouvintes. CoDAS 30(4):1–7CrossRef
48.
Zurück zum Zitat Mirz F, Zachariae R, Andersen SE, Nielsen AG, Johansen LV, Bjerring P et al (1999) The low-power laser in the treatment of tinnitus. Clin Otolaryngol 24:346–354PubMedCrossRef Mirz F, Zachariae R, Andersen SE, Nielsen AG, Johansen LV, Bjerring P et al (1999) The low-power laser in the treatment of tinnitus. Clin Otolaryngol 24:346–354PubMedCrossRef
49.
Zurück zum Zitat Park YM, Na WS, Park IY, Suh MW, Rhee CK, Chung PS et al (2013) Trans-canal laser irradiation reduces tinnitus perception of salicylate treated rat. Neurosci Lett 544:131–135PubMedCrossRef Park YM, Na WS, Park IY, Suh MW, Rhee CK, Chung PS et al (2013) Trans-canal laser irradiation reduces tinnitus perception of salicylate treated rat. Neurosci Lett 544:131–135PubMedCrossRef
50.
Zurück zum Zitat Rhee C-K, Bahk CW, Kim SH, Ahn JC, Jung JY, Chung PS, Suh MW (2012) Effect of low-level laser treatment on cochlea hair cell recovery after acute acoustic trauma. J Biomed Optics 17(6):068002CrossRef Rhee C-K, Bahk CW, Kim SH, Ahn JC, Jung JY, Chung PS, Suh MW (2012) Effect of low-level laser treatment on cochlea hair cell recovery after acute acoustic trauma. J Biomed Optics 17(6):068002CrossRef
51.
Zurück zum Zitat Montazeri K, Mahmoudian S, Razaghi Z, Farhadi M (2017) Alterations in Auditory Electrophysiological Responses Associated With Temporary Suppression of Tinnitus Induced by Low-Level Laser Therapy: A Before-After Case Series. J Lasers Med Sci 8(Suppl 1):S38–S45PubMedPubMedCentralCrossRef Montazeri K, Mahmoudian S, Razaghi Z, Farhadi M (2017) Alterations in Auditory Electrophysiological Responses Associated With Temporary Suppression of Tinnitus Induced by Low-Level Laser Therapy: A Before-After Case Series. J Lasers Med Sci 8(Suppl 1):S38–S45PubMedPubMedCentralCrossRef
52.
Zurück zum Zitat Okhovat A, Berjis N, Okhovat H, Malekpour A, Abtahi H (2011) Low-level laser for treatment of tinnitus: a self-controlled clinical trial. JRMS 16(1):33–38PubMedPubMedCentral Okhovat A, Berjis N, Okhovat H, Malekpour A, Abtahi H (2011) Low-level laser for treatment of tinnitus: a self-controlled clinical trial. JRMS 16(1):33–38PubMedPubMedCentral
53.
Zurück zum Zitat Chandra N, Chang K, Lee A, Shekhawat GS, Searchifield GD (2018) Psychometric validity, reliability, and responsiveness of the Tinnitus Functional Index. J Am Acad Audiol 29(7):609–625PubMedCrossRef Chandra N, Chang K, Lee A, Shekhawat GS, Searchifield GD (2018) Psychometric validity, reliability, and responsiveness of the Tinnitus Functional Index. J Am Acad Audiol 29(7):609–625PubMedCrossRef
54.
Zurück zum Zitat Siedentopf CM, Ischebeck A, Haala IA, Mottaghy FM, Schikora D, Verius M et al (2007) Neural correlates of transmeatal cochlear laser (TCL) stimulation in healthy human subjects. Neurosci Lett 411:189–193PubMedCrossRef Siedentopf CM, Ischebeck A, Haala IA, Mottaghy FM, Schikora D, Verius M et al (2007) Neural correlates of transmeatal cochlear laser (TCL) stimulation in healthy human subjects. Neurosci Lett 411:189–193PubMedCrossRef
55.
Zurück zum Zitat Swain SK, Nayak S, Ravan JR, Sahu MC (2016) Tinnitus and its current treatment–Still an enigma in medicine. J Formos Med Assoc 115(3):139–144PubMedCrossRef Swain SK, Nayak S, Ravan JR, Sahu MC (2016) Tinnitus and its current treatment–Still an enigma in medicine. J Formos Med Assoc 115(3):139–144PubMedCrossRef
Metadaten
Titel
The effects of photobiomodulation therapy in individuals with tinnitus and without hearing loss
verfasst von
Mirele Regina Silva
Amanda Rodrigues Scheffer
Roberto Sávio de Assunção Bastos
Maria Cristina Chavantes
Maria Fernanda Capoani Garcia Mondelli
Publikationsdatum
10.08.2022
Verlag
Springer London
Erschienen in
Lasers in Medical Science / Ausgabe 9/2022
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-022-03614-z

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