Skip to main content
Erschienen in: Pediatric Radiology 12/2022

13.05.2022 | Original Article

Ultrasound findings of acute pancreatitis in children

verfasst von: Andrew T. Trout, Rupesh Patel, Jaimie D. Nathan, Tom K. Lin, David S. Vitale, Alexander Nasr, Bin Zhang, Maisam Abu-El-Haija

Erschienen in: Pediatric Radiology | Ausgabe 12/2022

Einloggen, um Zugang zu erhalten

Abstract

Background

Studies systematically documenting US findings in children with acute pancreatitis are limited. Pancreas duct dilation is described as the most reliable finding of acute pancreatitis but this has not been rigorously examined in children.

Objective

To systematically document US findings in children with acute pancreatitis and to define interobserver agreement on those findings.

Materials and methods

In this cross-sectional study we retrospectively reviewed images for all pediatric patients <18 years of age who had been prospectively enrolled in a registry of patients with index admissions for acute pancreatitis between March 2013 and July 2020. Two blinded observers (R1, R2) reviewed the first transabdominal US examination performed within 2 weeks of the pancreatitis attack for each patient.

Results

In 141 children, US was performed at a median of 1 day (interquartile range [IQR]: 0, 1) following acute attack. Thirty-three (23%, R1) and 38 (27%, R2) children had no abnormal findings on US. Peripancreatic edema was the most frequent finding documented by both reviewers (63% R1, 54% R2). The pancreatic duct was visible in only 35% of the children and was dilated in only 12% (R1) and 14% (R2). There was substantial to almost-perfect agreement between reviewers on findings of acute pancreatitis (κ=0.62–1), including duct visibility.

Conclusion

Peripancreatic edema was the most frequently identified finding in children with acute pancreatitis, present in up to 63%, with almost perfect interobserver agreement. Duct dilation, cited in the literature as a reliable finding of acute pancreatitis, was rarely identified in our sample.
Literatur
1.
Zurück zum Zitat Morinville VD, Husain SZ, Bai H et al (2012) Definitions of pediatric pancreatitis and survey of present clinical practices. J Pediatr Gastroenterol Nutr 55:261–265CrossRefPubMedPubMedCentral Morinville VD, Husain SZ, Bai H et al (2012) Definitions of pediatric pancreatitis and survey of present clinical practices. J Pediatr Gastroenterol Nutr 55:261–265CrossRefPubMedPubMedCentral
2.
Zurück zum Zitat Abu-El-Haija M, Kumar S, Quiros JA et al (2018) Management of acute pancreatitis in the pediatric population: a clinical report from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition pancreas committee. J Pediatr Gastroenterol Nutr 66:159–176CrossRefPubMedPubMedCentral Abu-El-Haija M, Kumar S, Quiros JA et al (2018) Management of acute pancreatitis in the pediatric population: a clinical report from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition pancreas committee. J Pediatr Gastroenterol Nutr 66:159–176CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Abu-El-Haija M, Kumar S, Szabo F et al (2017) Classification of acute pancreatitis in the pediatric population: clinical report from the NASPGHAN pancreas committee. J Pediatr Gastroenterol Nutr 64:984–990CrossRefPubMed Abu-El-Haija M, Kumar S, Szabo F et al (2017) Classification of acute pancreatitis in the pediatric population: clinical report from the NASPGHAN pancreas committee. J Pediatr Gastroenterol Nutr 64:984–990CrossRefPubMed
4.
Zurück zum Zitat Trout AT, Anupindi SA, Freeman AJ et al (2020) North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and the Society for Pediatric Radiology joint position paper on noninvasive imaging of pediatric pancreatitis: literature summary and recommendations. J Pediatr Gastroenterol Nutr 72:151–167CrossRef Trout AT, Anupindi SA, Freeman AJ et al (2020) North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and the Society for Pediatric Radiology joint position paper on noninvasive imaging of pediatric pancreatitis: literature summary and recommendations. J Pediatr Gastroenterol Nutr 72:151–167CrossRef
5.
Zurück zum Zitat Trout AT, Ayyala RS, Murati MA et al (2021) Current state of imaging of pediatric pancreatitis: AJR expert panel narrative review. AJR Am J Roentgenol 217:265–277CrossRefPubMedPubMedCentral Trout AT, Ayyala RS, Murati MA et al (2021) Current state of imaging of pediatric pancreatitis: AJR expert panel narrative review. AJR Am J Roentgenol 217:265–277CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Abu-El-Haija M, Lin TK, Palermo J (2014) Update to the management of pediatric acute pancreatitis: highlighting areas in need of research. J Pediatr Gastroenterol Nutr 58:689–693CrossRefPubMed Abu-El-Haija M, Lin TK, Palermo J (2014) Update to the management of pediatric acute pancreatitis: highlighting areas in need of research. J Pediatr Gastroenterol Nutr 58:689–693CrossRefPubMed
7.
Zurück zum Zitat Orkin SH, Trout AT, Fei L et al (2019) Sensitivity of biochemical and imaging findings for the diagnosis of acute pancreatitis in children. J Pediatr 213:143–148.e2CrossRefPubMedPubMedCentral Orkin SH, Trout AT, Fei L et al (2019) Sensitivity of biochemical and imaging findings for the diagnosis of acute pancreatitis in children. J Pediatr 213:143–148.e2CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Richardson R, Morin CE, Wheeler CA et al (2021) Ultrasound has limited diagnostic utility in children with acute lymphoblastic leukemia developing pancreatitis. Pediatr Blood Cancer 68:e28730CrossRefPubMed Richardson R, Morin CE, Wheeler CA et al (2021) Ultrasound has limited diagnostic utility in children with acute lymphoblastic leukemia developing pancreatitis. Pediatr Blood Cancer 68:e28730CrossRefPubMed
9.
Zurück zum Zitat Chao HC, Lin SJ, Kong MS et al (2000) Sonographic evaluation of the pancreatic duct in normal children and children with pancreatitis. J Ultrasound Med 19:757–763CrossRefPubMed Chao HC, Lin SJ, Kong MS et al (2000) Sonographic evaluation of the pancreatic duct in normal children and children with pancreatitis. J Ultrasound Med 19:757–763CrossRefPubMed
10.
Zurück zum Zitat Siegel MJ, Martin KW, Worthington JL (1987) Normal and abnormal pancreas in children: US studies. Radiology 165:15–18CrossRefPubMed Siegel MJ, Martin KW, Worthington JL (1987) Normal and abnormal pancreas in children: US studies. Radiology 165:15–18CrossRefPubMed
11.
Zurück zum Zitat Sweeny KF, Lin TK, Nathan JD et al (2019) Rapid progression of acute pancreatitis to acute recurrent pancreatitis in children. J Pediatr Gastroenterol Nutr 68:104–109CrossRefPubMedPubMedCentral Sweeny KF, Lin TK, Nathan JD et al (2019) Rapid progression of acute pancreatitis to acute recurrent pancreatitis in children. J Pediatr Gastroenterol Nutr 68:104–109CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Vitale DS, Hornung L, Lin TK et al (2019) Blood urea nitrogen elevation is a marker for pediatric severe acute pancreatitis. Pancreas 48:363–366CrossRefPubMedPubMedCentral Vitale DS, Hornung L, Lin TK et al (2019) Blood urea nitrogen elevation is a marker for pediatric severe acute pancreatitis. Pancreas 48:363–366CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRefPubMed Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRefPubMed
14.
Zurück zum Zitat Artunduaga M, Grover AS, Callahan MJ (2021) Acute pancreatitis in children: a review with clinical perspectives to enhance imaging interpretation. Pediatr Radiol 51:1970–1982CrossRefPubMed Artunduaga M, Grover AS, Callahan MJ (2021) Acute pancreatitis in children: a review with clinical perspectives to enhance imaging interpretation. Pediatr Radiol 51:1970–1982CrossRefPubMed
15.
Zurück zum Zitat Di Serafino M, Vitale V, Severino R et al (2019) Pediatric ultrasonography of the pancreas: normal and abnormal findings. J Ultrasound 22:261–272CrossRefPubMed Di Serafino M, Vitale V, Severino R et al (2019) Pediatric ultrasonography of the pancreas: normal and abnormal findings. J Ultrasound 22:261–272CrossRefPubMed
16.
Zurück zum Zitat Restrepo R, Hagerott HE, Kulkarni S et al (2016) Acute pancreatitis in pediatric patients: demographics, etiology, and diagnostic imaging. AJR Am J Roentgenol 206:632–644CrossRefPubMed Restrepo R, Hagerott HE, Kulkarni S et al (2016) Acute pancreatitis in pediatric patients: demographics, etiology, and diagnostic imaging. AJR Am J Roentgenol 206:632–644CrossRefPubMed
17.
Zurück zum Zitat Choi CW, Kim GH, Kang DH et al (2010) Associated factors for a hyperechogenic pancreas on endoscopic ultrasound. World J Gastroenterol 16:4329–4334CrossRefPubMedPubMedCentral Choi CW, Kim GH, Kang DH et al (2010) Associated factors for a hyperechogenic pancreas on endoscopic ultrasound. World J Gastroenterol 16:4329–4334CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Worthen NJ, Beabeau D (1982) Normal pancreatic echogenicity: relation to age and body fat. AJR Am J Roentgenol 139:1095–1098CrossRefPubMed Worthen NJ, Beabeau D (1982) Normal pancreatic echogenicity: relation to age and body fat. AJR Am J Roentgenol 139:1095–1098CrossRefPubMed
19.
Zurück zum Zitat Abu-El-Haija M, Lowe M, Barth B et al (2020) Pediatric chronic pancreatitis without prior acute or acute recurrent pancreatitis: a report from the INSPPIRE consortium. Pancreatology 20:781–784CrossRefPubMed Abu-El-Haija M, Lowe M, Barth B et al (2020) Pediatric chronic pancreatitis without prior acute or acute recurrent pancreatitis: a report from the INSPPIRE consortium. Pancreatology 20:781–784CrossRefPubMed
Metadaten
Titel
Ultrasound findings of acute pancreatitis in children
verfasst von
Andrew T. Trout
Rupesh Patel
Jaimie D. Nathan
Tom K. Lin
David S. Vitale
Alexander Nasr
Bin Zhang
Maisam Abu-El-Haija
Publikationsdatum
13.05.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Radiology / Ausgabe 12/2022
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-022-05381-z

Weitere Artikel der Ausgabe 12/2022

Pediatric Radiology 12/2022 Zur Ausgabe

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

13.04.2024 Klinik aktuell Kongressbericht

Die Teilnehmer eines Forums beim DGIM-Kongress waren sich einig: Fehler in der Medizin sind häufig in ungeeigneten Prozessen und mangelnder Kommunikation begründet. Gespräche mit Patienten und im Team können helfen.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.