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08.05.2024 | Research
A survey of preferences and expectations for surgical interventions targeting atonic seizures in Lennox-Gastaut syndrome
Erschienen in: Child's Nervous System
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Purpose
To assess preferences and outcome expectations for vagus nerve stimulation (VNS) and corpus callosotomy (CC) surgeries in the treatment of atonic seizure in Lennox-Gastaut syndrome (LGS).
Methods
A total of 260 surveys were collected from patients are caregivers of LGS patients via Research Electronic Data Capture (REDCap).
Results
Respondents reported an average acceptable atonic seizure reduction rate of 55.9% following VNS and 74.7% following CC. 21.3% (n = 50) were willing to be randomized. Respondents reported low willingness for randomization and a higher seizure reduction expectation with CC.
Conclusion
Our findings guide surgical approaches for clinicians to consider patient preference in order to design future studies comparing effectiveness between these two procedures.