Erschienen in:
29.06.2022 | Editorial
Acute severe hepatitis of unknown origin in children: considerations from the perspective of immunology
verfasst von:
Si-Hao Gao, Meng-Chun Gong, Hong-Mei Song
Erschienen in:
World Journal of Pediatrics
|
Ausgabe 8/2022
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Excerpt
Acute severe hepatitis of unknown origin in children, since it was firstly reported in Scotland on March 31, 2022, has become an international concern with a high risk of acute liver failure requiring liver transplant. The typical causes for hepatitis have been ruled out and investigations revealed possible relationship between the disease and two potential pathogens, a special form of human adenovirus (HAdV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Acute hepatitis has been reported in children with multisystem inflammatory syndrome (MIS-C) and incorporating insights from the immunology perspective is necessary to fully understand this disease. …