Erschienen in:
31.10.2023 | ASO Author Reflections
ASO Author Reflections: Postoperative Carbohydrate Antigen 19-9 Levels Become a Reliable Biomarker for Establishing Intensity-Stratified Adjuvant Treatments in Pancreatic Ductal Adenocarcinoma
verfasst von:
Kyohei Ariake, MD, Takaho Okada, MD, Haruyuki Tsuchiya, MD, Daiki Kuboki, MD, Kimiya Maemura, MD, Hidetaka Ichikawa, MD, Tomoyoshi Tachibana, MD, Naoya Akazawa, MD, Tomoya Abe, MD, Tetsuya Kakita, MD, Masaya Oikawa, MD, Takashi Tsuchiya, MD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 1/2024
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Excerpt
Adjuvant treatment for pancreatic cancer (PaCa) is an essential step for improving survival. Although several guidelines recommended adjuvant treatment, recommended regimens are different according to guidelines.
1 Adequate treatment regimens are not still established, and the intensity of treatments is not classified according to the risk after resection. Stage classification is one of the most reliable indicators for deciding the regimens of adjuvant treatment in gastric or colorectal cancer.
2, 3 However, PaCa often is treated preoperatively by chemotherapy or chemoradiotherapy, and there is some concern regarding how this treatment may affect postoperative stage classification.
4 Taken together, there are two clinical questions about whether intensity-stratified adjuvant treatments are necessary for PaCa, and stage classification can become a useful indicator when considering the regimens of adjuvant treatment applied in other gastrointestinal cancers. …
