Ausgabe 1/2010
Inhalt (90 Artikel)
IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients
Michal Rajski, Rosanna Zanetti-Dällenbach, Brigitte Vogel, Richard Herrmann, Christoph Rochlitz, Martin Buess
Basic and clinical significance of IGF-I-induced signatures in cancer
Haim Werner, Ilan Bruchim
A randomized phase II study of carboplatin plus pegylated liposomal doxorubicin versus carboplatin plus paclitaxel in platinum sensitive ovarian cancer patients: a Hellenic Cooperative Oncology Group study
Dimitrios Bafaloukos, Helena Linardou, Gerasimos Aravantinos, Christos Papadimitriou, Aristotelis Bamias, George Fountzilas, Haralabos P Kalofonos, Paris Kosmidis, Eleni Timotheadou, Thomas Makatsoris, Epaminondas Samantas, Evangelos Briasoulis, Christos Christodoulou, Pavlos Papakostas, Dimitrios Pectasides, Athanasios M Dimopoulos
Suicide-related behaviors in older patients with new anti-epileptic drug use: data from the VA hospital system
Anne C VanCott, Joyce A Cramer, Laurel A Copeland, John E Zeber, Michael A Steinman, Jeffrey J Dersh, Mark E Glickman, Eric M Mortensen, Megan E Amuan, Mary Jo Pugh
An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: the GRACE-IMMUNE study
Benjamin D Brown, Jérémie Nsengimana, Jennifer H Barrett, Richard A Lawrence, Lori Steiner, Suzanne Cheng, D Timothy Bishop, Nilesh J Samani, Stephen G Ball, Anthony J Balmforth, Alistair S Hall
The interleukin-1 cluster, dyslipidaemia and risk of myocardial infarction
Bernard Keavney
An in-depth assessment of a diagnosis-based risk adjustment model based on national health insurance claims: the application of the Johns Hopkins Adjusted Clinical Group case-mix system in Taiwan
Hsien-Yen Chang, Jonathan P Weiner
Access to pain treatment as a human right
Diederik Lohman, Rebecca Schleifer, Joseph J Amon
Ruling out coronary heart disease in primary care patients with chest pain: a clinical prediction score
Baris Gencer, Paul Vaucher, Lilli Herzig, François Verdon, Christiane Ruffieux, Stefan Bösner, Bernard Burnand, Thomas Bischoff, Norbert Donner-Banzhoff, Bernard Favrat
The effectiveness of the McKenzie method in addition to first-line care for acute low back pain: a randomized controlled trial
Luciana AC Machado, Chris G Maher, Rob D Herbert, Helen Clare, James H McAuley
Incidence, detection, and tumour stage of breast cancer in a cohort of Italian women with negative screening mammography report recommending early (short-interval) rescreen
Alessandra Ravaioli, Flavia Foca, Americo Colamartini, Fabio Falcini, Carlo Naldoni, Alba C Finarelli, Priscilla Sassoli de Bianchi, Lauro Bucchi
A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma
Hong Fan, Dongsheng Liu, Xuemei Qiu, Fengchang Qiao, Qingxiang Wu, Xianwei Su, Feng Zhang, Yunwei Song, Zhujiang Zhao, Wei Xie
Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection
Shawn A Ritchie, Pearson WK Ahiahonu, Dushmanthi Jayasinghe, Doug Heath, Jun Liu, Yingshen Lu, Wei Jin, Amir Kavianpour, Yasuyo Yamazaki, Amin M Khan, Mohammad Hossain, Khine Khine Su-Myat, Paul L Wood, Kevin Krenitsky, Ichiro Takemasa, Masakazu Miyake, Mitsugu Sekimoto, Morito Monden, Hisahiro Matsubara, Fumio Nomura, Dayan B Goodenowe
Mitf-Mdel, a novel melanocyte/melanoma-specific isoform of microphthalmia-associated transcription factor-M, as a candidate biomarker for melanoma
Yixiang Wang, Soroosh Radfar, Suhu Liu, Adam I Riker, Hung T Khong
Frequency and circumstances of placebo use in clinical practice - a systematic review of empirical studies
Margrit Fässler, Karin Meissner, Antonius Schneider, Klaus Linde
Neonatal seizures in a rural Kenyan District Hospital: aetiology, Incidence and outcome of hospitalization
Michael Mwaniki, Ali Mathenge, Samson Gwer, Neema Mturi, Evasius Bauni, Charles RJC Newton, James Berkley, Richard Idro
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
Kenneth F Schulz, Douglas G Altman, David Moher
The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A
S Dedieu, X Canron, HR Rezvani, M Bouchecareilh, F Mazurier, R Sinisi, M Zanda, M Moenner, A Bikfalvi, S North
Reporting methods in studies developing prognostic models in cancer: a review
Susan Mallett, Patrick Royston, Susan Dutton, Rachel Waters, Douglas G Altman
Reporting performance of prognostic models in cancer: a review
Susan Mallett, Patrick Royston, Rachel Waters, Susan Dutton, Douglas G Altman
Does targeting manual therapy and/or exercise improve patient outcomes in nonspecific low back pain? A systematic review
Peter Kent, Hanne L Mjøsund, Ditte HD Petersen
Temporal trends in hospitalisation for stroke recurrence following incident hospitalisation for stroke in Scotland
James Lewsey, Pardeep S Jhund, Michelle Gillies, Jim WT Chalmers, Adam Redpath, Andrew Briggs, Matthew Walters, Peter Langhorne, Simon Capewell, John JV McMurray, Kate MacIntyre
Transparent and accurate reporting increases reliability, utility, and impact of your research: reporting guidelines and the EQUATOR Network
Iveta Simera, David Moher, Allison Hirst, John Hoey, Kenneth F Schulz, Douglas G Altman
Chromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumors
Mara Silva, Isabel Veiga, Franclim R Ribeiro, Joana Vieira, Carla Pinto, Manuela Pinheiro, Bárbara Mesquita, Catarina Santos, Marta Soares, José Dinis, Lúcio Santos, Paula Lopes, Mariana Afonso, Carlos Lopes, Manuel R Teixeira
The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo
Jodie M Fleming, Tyler C Miller, Mariam Quinones, Zhen Xiao, Xia Xu, Matthew J Meyer, Erika Ginsburg, Timothy D Veenstra, Barbara K Vonderhaar
BODE-Index vs HADO-Score in Chronic Obstructive Pulmonary Disease: Which one to use in general practice?
Cristóbal Esteban, José M Quintana, Javier Moraza, Myriam Aburto, Urko Aguirre, José I Aguirregomoscorta, Susana Aizpiri, Luis V Basualdo, Alberto Capelastegui
Cardiovascular risk assessment - From individual risk prediction to estimation of global risk and change in risk in the population
John A Batsis, Francisco Lopez-Jimenez
Symptomatic treatment (ibuprofen) or antibiotics (ciprofloxacin) for uncomplicated urinary tract infection? - Results of a randomized controlled pilot trial
Jutta Bleidorn, Ildikó Gágyor, Michael M Kochen, Karl Wegscheider, Eva Hummers-Pradier
What is a clinical pathway? Development of a definition to inform the debate
Leigh Kinsman, Thomas Rotter, Erica James, Pamela Snow, Jon Willis
Physical activity and depressive symptoms in adolescents: a prospective study
Catherine Rothon, Phil Edwards, Kamaldeep Bhui, Russell M Viner, Stephanie Taylor, Stephen A Stansfeld
US public opinion regarding proposed limits on resident physician work hours
Alexander B Blum, Farbod Raiszadeh, Sandra Shea, David Mermin, Peter Lurie, Christopher P Landrigan, Charles A Czeisler
Chronic fatigue syndrome: Harvey and Wessely's (bio)psychosocial model versus a bio(psychosocial) model based on inflammatory and oxidative and nitrosative stress pathways
Michael Maes, Frank NM Twisk
Triple antiplatelet therapy for preventing vascular events: a systematic review and meta-analysis
Chamila Geeganage, Robert Wilcox, Philip MW Bath
The impact of herpes zoster and post-herpetic neuralgia on quality-of-life
Robert W Johnson, Didier Bouhassira, George Kassianos, Alain Leplège, Kenneth E Schmader, Thomas Weinke
Brief psychological therapies for anxiety and depression in primary care: meta-analysis and meta-regression
John Cape, Craig Whittington, Marta Buszewicz, Paul Wallace, Lisa Underwood
Does chocolate reduce blood pressure? A meta-analysis
Karin Ried, Thomas Sullivan, Peter Fakler, Oliver R Frank, Nigel P Stocks
Reduced acquisition and reactivation of human papillomavirus infections among older women treated with cryotherapy: results from a randomized trial in South Africa
Sylvia Taylor, Chunhui Wang, Thomas C Wright, Lynette Denny, Wei-Yann Tsai, Louise Kuhn
Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan
H Teede, A Deeks, L Moran
Zinc Finger Nucleases as tools to understand and treat human diseases
David Davis, David Stokoe
Neonatal hypothermia and associated risk factors among newborns of southern Nepal
Luke C Mullany, Joanne Katz, Subarna K Khatry, Steven C LeClerq, Gary L Darmstadt, James M Tielsch
Hypoxia inducible factor 1α gene (HIF-1α) splice variants: potential prognostic biomarkers in breast cancer
Jean-Philippe Dales, Nathalie Beaufils, Monique Silvy, Christophe Picard, Vanessa Pauly, Vincent Pradel, Christine Formisano-Tréziny, Pascal Bonnier, Sophie Giusiano, Colette Charpin, Jean Gabert
Hypoxia-specific targets in cancer therapy: role of splice variants
Dirk Vordermark
Managing hyperemesis gravidarum: a multimodal challenge
JK Jueckstock, R Kaestner, I Mylonas
Targeted exercise against osteoporosis: A systematic review and meta-analysis for optimising bone strength throughout life
Riku Nikander, Harri Sievänen, Ari Heinonen, Robin M Daly, Kirsti Uusi-Rasi, Pekka Kannus
Relationship between knee and ankle degeneration in a population of organ donors
Carol Muehleman, Arkady Margulis, Won C Bae, Koichi Masuda
Erratum to: Development of lower limb range of motion from early childhood to adolescence in cerebral palsy: a population-based study
Eva Nordmark, Gunnar Hägglund, Henrik Lauge-Pedersen, Philippe Wagner, Lena Westbom
Enhancement drugs: are there limits to what we should enhance and why?
Morten Hesse
Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety
Alan G Wade, Ian Ford, Gordon Crawford, Alex McConnachie, Tali Nir, Moshe Laudon, Nava Zisapel
Chest compressions before defibrillation for out-of-hospital cardiac arrest: A meta-analysis of randomized controlled clinical trials
Pascal Meier, Paul Baker, Daniel Jost, Ian Jacobs, Bettina Henzi, Guido Knapp, Comilla Sasson
Routine resite of peripheral intravenous devices every 3 days did not reduce complications compared with clinically indicated resite: a randomised controlled trial
Claire M Rickard, Damhnat McCann, Jane Munnings, Matthew R McGrail
Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers
Siv K Bøhn, Mari C Myhrstad, Magne Thoresen, Marit Holden, Anette Karlsen, Siv Haugen Tunheim, Iris Erlund, Mette Svendsen, Ingebjørg Seljeflot, Jan Ø Moskaug, Asim K Duttaroy, Petter Laake, Harald Arnesen, Serena Tonstad, Andrew Collins, Christan A Drevon, Rune Blomhoff
An introduction to standardized clinical nomenclature for dysmorphic features: the Elements of Morphology project
Leslie G Biesecker
Decisions at the end of life: have we come of age?
Linda Emanuel, Karen Glasser Scandrett
Predictors of pain intensity and persistence in a prospective Italian cohort of patients with herpes zoster: relevance of smoking, trauma and antiviral therapy
Giustino Parruti, Monica Tontodonati, Cristina Rebuzzi, Ennio Polilli, Federica Sozio, Augusta Consorte, Adriana Agostinone, Francesco Di Masi, Gabriele Congedo, Domenico D'Antonio, Carla Granchelli, Claudio D'Amario, Carlo Carunchio, Lucio Pippa, Lamberto Manzoli, Antonio Volpi
Assessment of the quality and variability of health information on chronic pain websites using the DISCERN instrument
Jatin Kaicker, Victoria Borg Debono, Wilfred Dang, Norman Buckley, Lehana Thabane
The effects of increased dose of exercise-based therapies to enhance motor recovery after stroke: a systematic review and meta-analysis
Emma V Cooke, Kathryn Mares, Allan Clark, Raymond C Tallis, Valerie M Pomeroy
Surveys of current status in biomedical science grant review: funding organisations' and grant reviewers' perspectives
Sara Schroter, Trish Groves, Liselotte Højgaard
Normalisation process theory: a framework for developing, evaluating and implementing complex interventions
Elizabeth Murray, Shaun Treweek, Catherine Pope, Anne MacFarlane, Luciana Ballini, Christopher Dowrick, Tracy Finch, Anne Kennedy, Frances Mair, Catherine O'Donnell, Bie Nio Ong, Tim Rapley, Anne Rogers, Carl May
The VHL-dependent regulation of microRNAs in renal cancer
Calida S Neal, Michael Z Michael, Lesley H Rawlings, Mark B Van der Hoek, Jonathan M Gleadle
MicroRNAs: exploring a new dimension in the pathogenesis of kidney cancer
Nicole MA White, George M Yousef
Control of neglected tropical diseases needs a long-term commitment
Yaobi Zhang, Chad MacArthur, Likezo Mubila, Shawn Baker
Unresponsive wakefulness syndrome: a new name for the vegetative state or apallic syndrome
Steven Laureys, Gastone G Celesia, Francois Cohadon, Jan Lavrijsen, José León-Carrión, Walter G Sannita, Leon Sazbon, Erich Schmutzhard, Klaus R von Wild, Adam Zeman, Giuliano Dolce
The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model
Masa-Aki Shibata, Jayakrishna Ambati, Eiko Shibata, Romulo JC Albuquerque, Junji Morimoto, Yuko Ito, Yoshinori Otsuki
Analysis of sex and gender-specific research reveals a common increase in publications and marked differences between disciplines
Sabine Oertelt-Prigione, Roza Parol, Stephan Krohn, Robert Preißner, Vera Regitz-Zagrosek
Caesarean section without medical indications is associated with an increased risk of adverse short-term maternal outcomes: the 2004-2008 WHO Global Survey on Maternal and Perinatal Health
JP Souza, AM Gülmezoglu, P Lumbiganon, M Laopaiboon, G Carroli, B Fawole, P Ruyan
Notch signaling in glioblastoma: a developmental drug target?
Maria Maddalena Lino, Adrian Merlo, Jean-Louis Boulay
Can metabolomics in addition to genomics add to prognostic and predictive information in breast cancer?
Anthony Howell
One life ends, another begins: Management of a brain-dead pregnant mother-A systematic review-
Majid Esmaeilzadeh, Christine Dictus, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Michael Eichbaum, Stefan Hofer, Guido Engelmann, Hamidreza Fonouni, Mohammad Golriz, Jan Schmidt, Andreas Unterberg, Arianeb Mehrabi, Rezvan Ahmadi
How large are the nonspecific effects of acupuncture? A meta-analysis of randomized controlled trials
Klaus Linde, Karin Niemann, Antonius Schneider, Karin Meissner
Topical insulin-like growth factor 1 treatment using gelatin hydrogels for glucocorticoid-resistant sudden sensorineural hearing loss: a prospective clinical trial
Takayuki Nakagawa, Tatsunori Sakamoto, Harukazu Hiraumi, Yayoi S Kikkawa, Norio Yamamoto, Kiyomi Hamaguchi, Kazuya Ono, Masaya Yamamoto, Yasuhiko Tabata, Satoshi Teramukai, Shiro Tanaka, Harue Tada, Rie Onodera, Atsushi Yonezawa, Ken-ichi Inui, Juichi Ito
MRI plaque imaging and its role in population-based studies
Chun Yuan, Jarett D Berry
Dyskinesias after neural transplantation in Parkinson's disease: what do we know and what is next?
Marios Politis
The potential interaction between clopidogrel and proton pump inhibitors: a systematic review
Joao Paulo de Aquino Lima, James M Brophy
The promise and pitfalls of the internet for cognitive behavioral therapy
Gerhard Andersson
Systematic review of the evidence relating FEV1decline to giving up smoking
Peter N Lee, John S Fry
Clinically significant changes in burden and depression among dementia caregivers following nursing home admission
Joseph E Gaugler, Mary S Mittelman, Kenneth Hepburn, Robert Newcomer
Increased plasma soluble endoglin levels as an indicator of cardiovascular alterations in hypertensive and diabetic patients
Ana M Blázquez-Medela, Luis García-Ortiz, Manuel A Gómez-Marcos, José I Recio-Rodríguez, Angel Sánchez-Rodríguez, José M López-Novoa, Carlos Martínez-Salgado
Obesity related methylation changes in DNA of peripheral blood leukocytes
Xiaoling Wang, Haidong Zhu, Harold Snieder, Shaoyong Su, David Munn, Gregory Harshfield, Bernard L Maria, Yanbin Dong, Frank Treiber, Bernard Gutin, Huidong Shi
Epigenetics and obesity: the devil is in the details
Paul W Franks, Charlotte Ling
Diagnosis and biomarkers of predementia in Alzheimer's disease
Orestes V Forlenza, Breno S Diniz, Wagner F Gattaz
A population-based case-control study of Selective Serotonin Reuptake Inhibitors (SSRIs) and breast cancer: The impact of duration of use, cumulative dose and latency
JE Ashbury, LE Lévesque, PA Beck, KJ Aronson