Erschienen in:
26.08.2023 | Breast Oncology
Breast Cancer Genes and Contralateral Prophylactic Mastectomy: Beyond BRCA
verfasst von:
Todd M. Tuttle, MD, MS, Jane Yuet Ching Hui, MD, MS
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 12/2023
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Excerpt
Multigene panel germline testing is one of the most useful and cost-effective tools for counseling patients with a newly diagnosed breast cancer. Genetic testing provides relevant information regarding the risks of associated malignancies, informs family members of their potential risks, and identifies patients who may be candidates for specific systemic therapies. Moreover, multigene panel testing can provide patients with a unilateral breast cancer information about their risk of a contralateral breast cancer (CBC). This information can then be used to guide management of the contralateral breast. …