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Erschienen in: Skeletal Radiology 11/2023

10.02.2023 | Review Article

Cystic lesions and bursae around the knee: do they matter in knee osteoarthritis?

verfasst von: Peter C. Thurlow, Nastaran Hosseini, Firoozeh Shomal Zadeh, Majid Chalian

Erschienen in: Skeletal Radiology | Ausgabe 11/2023

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Abstract

The cause of knee osteoarthritis (OA) and knee pain associated with OA is not well understood. Periarticular cystic lesions and bursae around the knee are among the most common morphologic features identified on MRI in the setting of OA. Despite widespread association of these lesions with knee OA and their inclusion in semiquantitative MRI scoring assessment systems for knee OA, the role that these lesions play in the development of knee pain and OA remains uncertain. In this discussion, we review the cystic lesions and bursae most commonly associated with OA of the knee, examine their relation and role in whole organ imaging assessments of OA, and present the literature investigating the associations of periarticular cysts and cyst-like lesions with knee pain and OA.
Literatur
1.
Zurück zum Zitat Disease GBD, Injury I, Prevalence C. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1545–602.CrossRef Disease GBD, Injury I, Prevalence C. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1545–602.CrossRef
2.
Zurück zum Zitat Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine. 2020;29–30: 100587.CrossRefPubMedPubMedCentral Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine. 2020;29–30: 100587.CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Losina E, Paltiel AD, Weinstein AM, Yelin E, Hunter DJ, Chen SP, et al. Lifetime medical costs of knee osteoarthritis management in the United States: impact of extending indications for total knee arthroplasty. Arthritis Care Res (Hoboken). 2015;67(2):203–15.CrossRef Losina E, Paltiel AD, Weinstein AM, Yelin E, Hunter DJ, Chen SP, et al. Lifetime medical costs of knee osteoarthritis management in the United States: impact of extending indications for total knee arthroplasty. Arthritis Care Res (Hoboken). 2015;67(2):203–15.CrossRef
4.
Zurück zum Zitat Wallace IJ, Worthington S, Felson DT, Jurmain RD, Wren KT, Maijanen H, et al. Knee osteoarthritis has doubled in prevalence since the mid-20th century. Proc Natl Acad Sci U S A. 2017;114(35):9332–6.CrossRefPubMedCentral Wallace IJ, Worthington S, Felson DT, Jurmain RD, Wren KT, Maijanen H, et al. Knee osteoarthritis has doubled in prevalence since the mid-20th century. Proc Natl Acad Sci U S A. 2017;114(35):9332–6.CrossRefPubMedCentral
5.
Zurück zum Zitat Peterfy CG, Guermazi A, Zaim S, Tirman PF, Miaux Y, White D, et al. Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis. Osteoarthr Cartil. 2004;12(3):177–90.CrossRef Peterfy CG, Guermazi A, Zaim S, Tirman PF, Miaux Y, White D, et al. Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis. Osteoarthr Cartil. 2004;12(3):177–90.CrossRef
7.
Zurück zum Zitat Kornaat PR, Bloem JL, Ceulemans RY, Riyazi N, Rosendaal FR, Nelissen RG, et al. Osteoarthritis of the knee: association between clinical features and MR imaging findings. Radiology. 2006;239(3):811–7.CrossRefPubMed Kornaat PR, Bloem JL, Ceulemans RY, Riyazi N, Rosendaal FR, Nelissen RG, et al. Osteoarthritis of the knee: association between clinical features and MR imaging findings. Radiology. 2006;239(3):811–7.CrossRefPubMed
8.
Zurück zum Zitat Hill CL, Gale DG, Chaisson CE, Skinner K, Kazis L, Gale ME, et al. Knee effusions, popliteal cysts, and synovial thickening: association with knee pain in osteoarthritis. J Rheumatol. 2001;28(6):1330–7. Hill CL, Gale DG, Chaisson CE, Skinner K, Kazis L, Gale ME, et al. Knee effusions, popliteal cysts, and synovial thickening: association with knee pain in osteoarthritis. J Rheumatol. 2001;28(6):1330–7.
9.
Zurück zum Zitat Felson DT, Chaisson CE, Hill CL, Totterman SM, Gale ME, Skinner KM, et al. The association of bone marrow lesions with pain in knee osteoarthritis. Ann Intern Med. 2001;134(7):541–9.CrossRefPubMed Felson DT, Chaisson CE, Hill CL, Totterman SM, Gale ME, Skinner KM, et al. The association of bone marrow lesions with pain in knee osteoarthritis. Ann Intern Med. 2001;134(7):541–9.CrossRefPubMed
10.
Zurück zum Zitat Hill CL, Gale DR, Chaisson CE, Skinner K, Kazis L, Gale ME, et al. Periarticular lesions detected on magnetic resonance imaging: prevalence in knees with and without symptoms. Arthritis Rheum. 2003;48(10):2836–44.CrossRefPubMed Hill CL, Gale DR, Chaisson CE, Skinner K, Kazis L, Gale ME, et al. Periarticular lesions detected on magnetic resonance imaging: prevalence in knees with and without symptoms. Arthritis Rheum. 2003;48(10):2836–44.CrossRefPubMed
11.
Zurück zum Zitat Hunter DJ, Lo GH, Gale D, Grainger AJ, Guermazi A, Conaghan PG. The reliability of a new scoring system for knee osteoarthritis MRI and the validity of bone marrow lesion assessment: BLOKS (Boston Leeds Osteoarthritis Knee Score). Ann Rheum Dis. 2008;67(2):206–11.CrossRefPubMed Hunter DJ, Lo GH, Gale D, Grainger AJ, Guermazi A, Conaghan PG. The reliability of a new scoring system for knee osteoarthritis MRI and the validity of bone marrow lesion assessment: BLOKS (Boston Leeds Osteoarthritis Knee Score). Ann Rheum Dis. 2008;67(2):206–11.CrossRefPubMed
12.
Zurück zum Zitat Hunter DJ, Guermazi A, Lo GH, Grainger AJ, Conaghan PG, Boudreau RM, et al. Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score). Osteoarthritis Cartilage. 2011;19(8):990–1002.CrossRefPubMedPubMedCentral Hunter DJ, Guermazi A, Lo GH, Grainger AJ, Conaghan PG, Boudreau RM, et al. Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score). Osteoarthritis Cartilage. 2011;19(8):990–1002.CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Guermazi A, Roemer FW, Haugen IK, Crema MD, Hayashi D. MRI-based semiquantitative scoring of joint pathology in osteoarthritis. Nat Rev Rheumatol. 2013;9(4):236–51.CrossRefPubMed Guermazi A, Roemer FW, Haugen IK, Crema MD, Hayashi D. MRI-based semiquantitative scoring of joint pathology in osteoarthritis. Nat Rev Rheumatol. 2013;9(4):236–51.CrossRefPubMed
14.
Zurück zum Zitat Giard MC, Pineda C. Ganglion cyst versus synovial cyst? Ultrasound characteristics through a review of the literature. Rheumatol Int. 2015;35(4):597–605.CrossRefPubMed Giard MC, Pineda C. Ganglion cyst versus synovial cyst? Ultrasound characteristics through a review of the literature. Rheumatol Int. 2015;35(4):597–605.CrossRefPubMed
15.
Zurück zum Zitat Marra MD, Crema MD, Chung M, Roemer FW, Hunter DJ, Zaim S, et al. MRI features of cystic lesions around the knee. Knee. 2008;15(6):423–38.CrossRefPubMed Marra MD, Crema MD, Chung M, Roemer FW, Hunter DJ, Zaim S, et al. MRI features of cystic lesions around the knee. Knee. 2008;15(6):423–38.CrossRefPubMed
16.
Zurück zum Zitat McCarthy CL, McNally EG. The MRI appearance of cystic lesions around the knee. Skeletal Radiol. 2004;33(4):187–209.CrossRefPubMed McCarthy CL, McNally EG. The MRI appearance of cystic lesions around the knee. Skeletal Radiol. 2004;33(4):187–209.CrossRefPubMed
17.
Zurück zum Zitat Malghem J, Vande BB, Lecouvet F, Lebon C, Maldague B. Atypical ganglion cysts. JBR-BTR. 2002;85(1):34–42.PubMed Malghem J, Vande BB, Lecouvet F, Lebon C, Maldague B. Atypical ganglion cysts. JBR-BTR. 2002;85(1):34–42.PubMed
18.
Zurück zum Zitat Tschirch FT, Schmid MR, Pfirrmann CW, Romero J, Hodler J, Zanetti M. Prevalence and size of meniscal cysts, ganglionic cysts, synovial cysts of the popliteal space, fluid-filled bursae, and other fluid collections in asymptomatic knees on MR imaging. AJR Am J Roentgenol. 2003;180(5):1431–6.CrossRefPubMed Tschirch FT, Schmid MR, Pfirrmann CW, Romero J, Hodler J, Zanetti M. Prevalence and size of meniscal cysts, ganglionic cysts, synovial cysts of the popliteal space, fluid-filled bursae, and other fluid collections in asymptomatic knees on MR imaging. AJR Am J Roentgenol. 2003;180(5):1431–6.CrossRefPubMed
19.
Zurück zum Zitat Kim IJ, Kim DH, Song YW, Guermazi A, Crema MD, Hunter DJ, et al. The prevalence of periarticular lesions detected on magnetic resonance imaging in middle-aged and elderly persons: a cross-sectional study. BMC Musculoskelet Disord. 2016;17:186.CrossRefPubMedPubMedCentral Kim IJ, Kim DH, Song YW, Guermazi A, Crema MD, Hunter DJ, et al. The prevalence of periarticular lesions detected on magnetic resonance imaging in middle-aged and elderly persons: a cross-sectional study. BMC Musculoskelet Disord. 2016;17:186.CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Dye SF, Vaupel GL, Dye CC. Conscious neurosensory mapping of the internal structures of the human knee without intraarticular anesthesia. Am J Sports Med. 1998;26(6):773–7.CrossRefPubMed Dye SF, Vaupel GL, Dye CC. Conscious neurosensory mapping of the internal structures of the human knee without intraarticular anesthesia. Am J Sports Med. 1998;26(6):773–7.CrossRefPubMed
21.
Zurück zum Zitat Miller TT, Staron RB, Koenigsberg T, Levin TL, Feldman F. MR imaging of Baker cysts: association with internal derangement, effusion, and degenerative arthropathy. Radiology. 1996;201(1):247–50.CrossRefPubMed Miller TT, Staron RB, Koenigsberg T, Levin TL, Feldman F. MR imaging of Baker cysts: association with internal derangement, effusion, and degenerative arthropathy. Radiology. 1996;201(1):247–50.CrossRefPubMed
22.
Zurück zum Zitat Hayashi D, Roemer FW, Dhina Z, Kwoh CK, Hannon MJ, Moore C, et al. Longitudinal assessment of cyst-like lesions of the knee and their relation to radiographic osteoarthritis and MRI-detected effusion and synovitis in patients with knee pain. Arthritis Res Ther. 2010;12(5):R172.CrossRefPubMedPubMedCentral Hayashi D, Roemer FW, Dhina Z, Kwoh CK, Hannon MJ, Moore C, et al. Longitudinal assessment of cyst-like lesions of the knee and their relation to radiographic osteoarthritis and MRI-detected effusion and synovitis in patients with knee pain. Arthritis Res Ther. 2010;12(5):R172.CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Ward EE, Jacobson JA, Fessell DP, Hayes CW, van Holsbeeck M. Sonographic detection of Baker’s cysts: comparison with MR imaging. AJR Am J Roentgenol. 2001;176(2):373–80.CrossRefPubMed Ward EE, Jacobson JA, Fessell DP, Hayes CW, van Holsbeeck M. Sonographic detection of Baker’s cysts: comparison with MR imaging. AJR Am J Roentgenol. 2001;176(2):373–80.CrossRefPubMed
24.
Zurück zum Zitat Torreggiani WC, Al-Ismail K, Munk PL, Roche C, Keogh C, Nicolaou S, et al. The imaging spectrum of Baker’s (Popliteal) cysts. Clin Radiol. 2002;57(8):681–91.CrossRef Torreggiani WC, Al-Ismail K, Munk PL, Roche C, Keogh C, Nicolaou S, et al. The imaging spectrum of Baker’s (Popliteal) cysts. Clin Radiol. 2002;57(8):681–91.CrossRef
25.
Zurück zum Zitat Chatzopoulos D, Moralidis E, Markou P, Makris V, Arsos G. Baker’s cysts in knees with chronic osteoarthritic pain: a clinical, ultrasonographic, radiographic and scintigraphic evaluation. Rheumatol Int. 2008;29(2):141–6.CrossRefPubMed Chatzopoulos D, Moralidis E, Markou P, Makris V, Arsos G. Baker’s cysts in knees with chronic osteoarthritic pain: a clinical, ultrasonographic, radiographic and scintigraphic evaluation. Rheumatol Int. 2008;29(2):141–6.CrossRefPubMed
26.
Zurück zum Zitat Cao Y, Jones G, Han W, Antony B, Wang X, Cicuttini F, et al. Popliteal cysts and subgastrocnemius bursitis are associated with knee symptoms and structural abnormalities in older adults: a cross-sectional study. Arthritis Res Ther. 2014;16(2):R59.CrossRefPubMedPubMedCentral Cao Y, Jones G, Han W, Antony B, Wang X, Cicuttini F, et al. Popliteal cysts and subgastrocnemius bursitis are associated with knee symptoms and structural abnormalities in older adults: a cross-sectional study. Arthritis Res Ther. 2014;16(2):R59.CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat de Miguel ME, Cobo Ibanez T, Uson Jaeger J, Bonilla Hernan G, Martin ME. Clinical and ultrasonographic findings related to knee pain in osteoarthritis. Osteoarthr Cartil. 2006;14(6):540–4.CrossRef de Miguel ME, Cobo Ibanez T, Uson Jaeger J, Bonilla Hernan G, Martin ME. Clinical and ultrasonographic findings related to knee pain in osteoarthritis. Osteoarthr Cartil. 2006;14(6):540–4.CrossRef
28.
Zurück zum Zitat Guermazi A, Hayashi D, Roemer FW, Niu J, Yang M, Lynch JA, et al. Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST study. Osteoarthr Cartil. 2010;18(11):1386–92.CrossRef Guermazi A, Hayashi D, Roemer FW, Niu J, Yang M, Lynch JA, et al. Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST study. Osteoarthr Cartil. 2010;18(11):1386–92.CrossRef
29.
Zurück zum Zitat Meredith DS, Losina E, Neumann G, Yoshioka H, Lang PK, Katz JN. Empirical evaluation of the inter-relationship of articular elements involved in the pathoanatomy of knee osteoarthritis using magnetic resonance imaging. BMC Musculoskelet Disord. 2009;10:133.CrossRefPubMedPubMedCentral Meredith DS, Losina E, Neumann G, Yoshioka H, Lang PK, Katz JN. Empirical evaluation of the inter-relationship of articular elements involved in the pathoanatomy of knee osteoarthritis using magnetic resonance imaging. BMC Musculoskelet Disord. 2009;10:133.CrossRefPubMedPubMedCentral
30.
Zurück zum Zitat Forbes JR, Helms CA, Janzen DL. Acute pes anserine bursitis: MR imaging. Radiology. 1995;194(2):525–7.CrossRefPubMed Forbes JR, Helms CA, Janzen DL. Acute pes anserine bursitis: MR imaging. Radiology. 1995;194(2):525–7.CrossRefPubMed
31.
Zurück zum Zitat Alvarez-Nemegyei J. Risk factors for pes anserinus tendinitis/bursitis syndrome: a case control study. J Clin Rheumatol. 2007;13(2):63–5.CrossRefPubMed Alvarez-Nemegyei J. Risk factors for pes anserinus tendinitis/bursitis syndrome: a case control study. J Clin Rheumatol. 2007;13(2):63–5.CrossRefPubMed
32.
Zurück zum Zitat Dirim B, Wangwinyuvirat M, Frank A, Cink V, Pretterklieber ML, Pastore D, et al. Communication between the proximal tibiofibular joint and knee via the subpopliteal recess: MR arthrography with histologic correlation and stratigraphic dissection. AJR Am J Roentgenol. 2008;191(2):W44-51.CrossRefPubMed Dirim B, Wangwinyuvirat M, Frank A, Cink V, Pretterklieber ML, Pastore D, et al. Communication between the proximal tibiofibular joint and knee via the subpopliteal recess: MR arthrography with histologic correlation and stratigraphic dissection. AJR Am J Roentgenol. 2008;191(2):W44-51.CrossRefPubMed
33.
Zurück zum Zitat Jerome D, McKendry R. Synovial cyst of the proximal tibiofibular joint. J Rheumatol. 2000;27(4):1096–8.PubMed Jerome D, McKendry R. Synovial cyst of the proximal tibiofibular joint. J Rheumatol. 2000;27(4):1096–8.PubMed
34.
Zurück zum Zitat Damron TA, Rock MG. Unusual manifestations of proximal tibiofibular joint synovial cysts. Orthopedics. 1997;20(3):225–30.CrossRefPubMed Damron TA, Rock MG. Unusual manifestations of proximal tibiofibular joint synovial cysts. Orthopedics. 1997;20(3):225–30.CrossRefPubMed
35.
Zurück zum Zitat Steiner E, Steinbach LS, Schnarkowski P, Tirman PF, Genant HK. Ganglia and cysts around joints. Radiol Clin North Am. 1996;34(2):395–425 (xi-xii).CrossRefPubMed Steiner E, Steinbach LS, Schnarkowski P, Tirman PF, Genant HK. Ganglia and cysts around joints. Radiol Clin North Am. 1996;34(2):395–425 (xi-xii).CrossRefPubMed
36.
Zurück zum Zitat Janzen DL, Peterfy CG, Forbes JR, Tirman PF, Genant HK. Cystic lesions around the knee joint: MR imaging findings. AJR Am J Roentgenol. 1994;163(1):155–61.CrossRefPubMed Janzen DL, Peterfy CG, Forbes JR, Tirman PF, Genant HK. Cystic lesions around the knee joint: MR imaging findings. AJR Am J Roentgenol. 1994;163(1):155–61.CrossRefPubMed
Metadaten
Titel
Cystic lesions and bursae around the knee: do they matter in knee osteoarthritis?
verfasst von
Peter C. Thurlow
Nastaran Hosseini
Firoozeh Shomal Zadeh
Majid Chalian
Publikationsdatum
10.02.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Skeletal Radiology / Ausgabe 11/2023
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-023-04295-7

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