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20.07.2022 | Review articles

Diagnostics of messenger ribonucleic acid (mRNA) severe acute respiratory syndrome-corona virus‑2 (SARS-CoV‑2) vaccination-associated myocarditis—A systematic review

verfasst von: Jan M. Federspiel, MD, Frank Ramsthaler, MD, Mattias Kettner, MD, Gerhard Mall, MD

Erschienen in: Rechtsmedizin | Ausgabe 2/2023

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Abstract

Background

During the recent pandemic with the severe acute respiratory syndrome-corona virus‑2 the first messenger ribonucleic acid (mRNA) vaccines were approved. To facilitate mass vaccination, confidence of the general population in these new vaccines is mandatory, which is in turn strongly dependent on the availability of reliable data on complications.

Objective

Summary of the current knowledge on mRNA vaccination-associated myocarditis as a potentially fatal side effect.

Methods

Systematic literature review.

Results

Diagnostic algorithm for the postmortem diagnosis of mRNA vaccination-associated myocarditis.

Conclusion

Autopsy series of fatalities following mRNA SARS-CoV‑2 vaccination up to 6 weeks with subsequent sophisticated and interdisciplinary work-up are necessary to complement clinical data on vaccination-associated myocarditis, especially regarding the incidence of fatal courses.

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Titel: Diagnostics of messenger ribonucleic acid (mRNA) severe acute respiratory syndrome-corona virus‑2 (SARS-CoV‑2) vaccination-associated myocarditis—A systematic review
verfasst von: Jan M. Federspiel, MD
Frank Ramsthaler, MD
Mattias Kettner, MD
Gerhard Mall, MD
Publikationsdatum: 20.07.2022
Verlag: Springer Medizin
Erschienen in: Rechtsmedizin / Ausgabe 2/2023
Print ISSN: 0937-9819
Elektronische ISSN: 1434-5196
DOI: https://doi.org/10.1007/s00194-022-00587-9

Springer Medizin

Diagnostics of messenger ribonucleic acid (mRNA) severe acute respiratory syndrome-corona virus‑2 (SARS-CoV‑2) vaccination-associated myocarditis—A systematic review

Abstract

Background

Objective

Methods

Results

Conclusion

Neu im Fachgebiet Rechtsmedizin

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

Background

Objective

Methods

Results

Conclusion

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