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Erschienen in: Heart Failure Reviews 5/2018

04.05.2018

Postmortem cardiac magnetic resonance in sudden cardiac death

verfasst von: Benedetta Guidi, Giovanni Donato Aquaro, Marco Gesi, Michele Emdin, Marco Di Paolo

Erschienen in: Heart Failure Reviews | Ausgabe 5/2018

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Abstract

Postmortem imaging is increasingly used in forensic practice as good complementary tool to conventional autopsy investigations. Over the last decade, postmortem cardiac magnetic resonance (PMCMR) imaging was introduced in forensic investigations of natural deaths related to cardiovascular diseases, which represent the most common causes of death in developed countries. Postmortem CMR application has yielded interesting results in ischemic myocardium injury investigations and in visualizing other pathological findings in the heart. This review presents the actual state of postmortem imaging for cardiovascular pathologies in cases of sudden cardiac death (SCD), taking into consideration both the advantages and limitations of PMCMR application.
Literatur
2.
Zurück zum Zitat Basso C, Burke M, Fornes P, Gallagher P, de Gouveia R, Sheppard M, Thiene G, van der Wal A, Association for European Cardiovascular Pathology (2010) Guidelines for autopsy investigation of sudden cardiac death. Pathologica 102(5):391–404PubMed Basso C, Burke M, Fornes P, Gallagher P, de Gouveia R, Sheppard M, Thiene G, van der Wal A, Association for European Cardiovascular Pathology (2010) Guidelines for autopsy investigation of sudden cardiac death. Pathologica 102(5):391–404PubMed
3.
Zurück zum Zitat Chugh SS, Reinier K, Teodorescu C, Evanado A, Kehr E, Al Samara M et al (2008) Epidemiology of sudden cardiac death: clinical and research implications. Prog Cardiovasc Dis 51(3):213–228CrossRefPubMedPubMedCentral Chugh SS, Reinier K, Teodorescu C, Evanado A, Kehr E, Al Samara M et al (2008) Epidemiology of sudden cardiac death: clinical and research implications. Prog Cardiovasc Dis 51(3):213–228CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Michaud K, Grabber S, Jackowski C, Bollmann MD, Doenz F, Mangin P (2014) Postmortem imaging of sudden cardiac death. Int J Legal Med 128(1):127–137CrossRefPubMed Michaud K, Grabber S, Jackowski C, Bollmann MD, Doenz F, Mangin P (2014) Postmortem imaging of sudden cardiac death. Int J Legal Med 128(1):127–137CrossRefPubMed
5.
Zurück zum Zitat Papadakis M, Sharma S, Cox S, Sheppard MN, Panoulas VF, Behr ER (2009) The magnitude of sudden cardiac death in the young: a death certificate-based review in England and Wales. Europace 11(10):1353–1358CrossRefPubMed Papadakis M, Sharma S, Cox S, Sheppard MN, Panoulas VF, Behr ER (2009) The magnitude of sudden cardiac death in the young: a death certificate-based review in England and Wales. Europace 11(10):1353–1358CrossRefPubMed
6.
Zurück zum Zitat Behr ER, Casey A, Sheppard M, Wright M, Bowker TJ, Davies MJ, McKenna WJ, Wood DA (2007) Sudden arrhythmic death syndrome: a national survey of sudden unexplained cardiac death. Heart 93(5):601–605CrossRefPubMedPubMedCentral Behr ER, Casey A, Sheppard M, Wright M, Bowker TJ, Davies MJ, McKenna WJ, Wood DA (2007) Sudden arrhythmic death syndrome: a national survey of sudden unexplained cardiac death. Heart 93(5):601–605CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Eckart RE, Shry EA, Burke AP, McNear JA, Appel DA, Castillo-Rojas LM, Avedissian L, Pearse LA, Potter RN, Tremaine L, Gentlesk PJ, Huffer L, Reich SS, Stevenson WG, Department of Defense Cardiovascular Death Registry Group (2011) Sudden death in young adults: an autopsy-based series of a population undergoing active surveillance. J Am Coll Cardiol 58(12):1254–1261CrossRefPubMed Eckart RE, Shry EA, Burke AP, McNear JA, Appel DA, Castillo-Rojas LM, Avedissian L, Pearse LA, Potter RN, Tremaine L, Gentlesk PJ, Huffer L, Reich SS, Stevenson WG, Department of Defense Cardiovascular Death Registry Group (2011) Sudden death in young adults: an autopsy-based series of a population undergoing active surveillance. J Am Coll Cardiol 58(12):1254–1261CrossRefPubMed
8.
Zurück zum Zitat Corrado D, Basso C, Rizzoli G, Schiavon M, Thiene G (2003) Does sports activity enhance the risk of sudden death in adolescents and young adults? J Am Coll Cardiol 42(11):1959–1963CrossRefPubMed Corrado D, Basso C, Rizzoli G, Schiavon M, Thiene G (2003) Does sports activity enhance the risk of sudden death in adolescents and young adults? J Am Coll Cardiol 42(11):1959–1963CrossRefPubMed
9.
Zurück zum Zitat Maron BJ, Doerer JJ, Haas TS, Tierney DM, Mueller FO (2009) Sudden deaths in young competitive athletes. Circulation 119(8):1085–1092CrossRefPubMed Maron BJ, Doerer JJ, Haas TS, Tierney DM, Mueller FO (2009) Sudden deaths in young competitive athletes. Circulation 119(8):1085–1092CrossRefPubMed
10.
Zurück zum Zitat Aquaro GD, Nucifora G, Pederzoli L, Strata E, De Marchi D, Todiere G et al (2012) Fat in left ventricular myocardium assessed by steady-state free precession pulse sequences. Int J Cardiovasc Imaging 28:813–821CrossRefPubMed Aquaro GD, Nucifora G, Pederzoli L, Strata E, De Marchi D, Todiere G et al (2012) Fat in left ventricular myocardium assessed by steady-state free precession pulse sequences. Int J Cardiovasc Imaging 28:813–821CrossRefPubMed
11.
Zurück zum Zitat Aquaro GD, Todiere G, Strata E, Barison A, Di Bella G, Lombardi M (2014) Usefulness of India ink artifact in steady-state free precession pulse sequences for detection and quantification of intramyocardial fat. J Magn Reson Imaging 40:126–132CrossRefPubMed Aquaro GD, Todiere G, Strata E, Barison A, Di Bella G, Lombardi M (2014) Usefulness of India ink artifact in steady-state free precession pulse sequences for detection and quantification of intramyocardial fat. J Magn Reson Imaging 40:126–132CrossRefPubMed
12.
Zurück zum Zitat Mavrogeni S, Apostolou D, Argyriou P, Velitsista S, Papa L, Efentakis S, Vernardos E, Kanoupaki M, Kanoupakis G, Manginas A (2017 Aug 17) T1 and T2 mapping in cardiology: “mapping the obscure object of desire”. Cardiology 138(4):207–217CrossRefPubMed Mavrogeni S, Apostolou D, Argyriou P, Velitsista S, Papa L, Efentakis S, Vernardos E, Kanoupaki M, Kanoupakis G, Manginas A (2017 Aug 17) T1 and T2 mapping in cardiology: “mapping the obscure object of desire”. Cardiology 138(4):207–217CrossRefPubMed
13.
Zurück zum Zitat Ugander M, Bagi PS, Oki AJ, Chen B, Hsu LY, Aletras AH, Shah S, Greiser A, Kellman P, Arai AE (2012) Myocardial edema as detected by pre-contrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarction. JACC Cardiovasc Imaging 5:596–603CrossRefPubMedPubMedCentral Ugander M, Bagi PS, Oki AJ, Chen B, Hsu LY, Aletras AH, Shah S, Greiser A, Kellman P, Arai AE (2012) Myocardial edema as detected by pre-contrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarction. JACC Cardiovasc Imaging 5:596–603CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Karamitsos TD, Piechnik SK, Banypersad SM, Fontana M, Ntusi NB, Ferreira VM, Whelan CJ, Myerson SG, Robson MD, Hawkins PN, Neubauer S, Moon JC (2013) Noncontrast T1 mapping for the diagnosis of cardiac amyloidosis. JACC Cardiovasc Imaging 6:488–497CrossRefPubMed Karamitsos TD, Piechnik SK, Banypersad SM, Fontana M, Ntusi NB, Ferreira VM, Whelan CJ, Myerson SG, Robson MD, Hawkins PN, Neubauer S, Moon JC (2013) Noncontrast T1 mapping for the diagnosis of cardiac amyloidosis. JACC Cardiovasc Imaging 6:488–497CrossRefPubMed
15.
Zurück zum Zitat Sado DM, White SK, Piechnik SK, Banypersad SM, Treibel T, Captur G, Fontana M, Maestrini V, Flett AS, Robson MD, Lachmann RH, Murphy E, Mehta A, Hughes D, Neubauer S, Elliott PM, Moon JC (2013) Identification and assessment of Anderson-Fabry disease by cardiovascular magnetic resonance noncontrast myocardial T1 mapping. Circ Cardiovasc Imaging 6:392–398CrossRefPubMed Sado DM, White SK, Piechnik SK, Banypersad SM, Treibel T, Captur G, Fontana M, Maestrini V, Flett AS, Robson MD, Lachmann RH, Murphy E, Mehta A, Hughes D, Neubauer S, Elliott PM, Moon JC (2013) Identification and assessment of Anderson-Fabry disease by cardiovascular magnetic resonance noncontrast myocardial T1 mapping. Circ Cardiovasc Imaging 6:392–398CrossRefPubMed
16.
Zurück zum Zitat Pedersen SF, Thrysoe SA, Robich MP, Paaske WP, Ringgaard S, Botker HE et al (2012) Assessment of intramyocardial hemorrhage by T1-weighted cardiovascular magnetic resonance in reperfused acute myocardial infarction. J Cardiovasc Magn Reson 14:59CrossRefPubMedPubMedCentral Pedersen SF, Thrysoe SA, Robich MP, Paaske WP, Ringgaard S, Botker HE et al (2012) Assessment of intramyocardial hemorrhage by T1-weighted cardiovascular magnetic resonance in reperfused acute myocardial infarction. J Cardiovasc Magn Reson 14:59CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Aquaro GD, Gabutti A, Meini M, Prontera C, Pasanisi E, Passino C, Emdin M, Lombardi M (2011) Silent myocardial damage in cocaine addicts. Heart 97:2056–2062CrossRefPubMed Aquaro GD, Gabutti A, Meini M, Prontera C, Pasanisi E, Passino C, Emdin M, Lombardi M (2011) Silent myocardial damage in cocaine addicts. Heart 97:2056–2062CrossRefPubMed
18.
Zurück zum Zitat Zech WD, Schwendener N, Persson A, Warntjes MJ, Jackowski C (2015) Postmortem MR quantification of the heart for characterization and differentiation of ischaemic myocardial lesions. Eur Radiol 25:2067–2073CrossRefPubMed Zech WD, Schwendener N, Persson A, Warntjes MJ, Jackowski C (2015) Postmortem MR quantification of the heart for characterization and differentiation of ischaemic myocardial lesions. Eur Radiol 25:2067–2073CrossRefPubMed
19.
Zurück zum Zitat Ma D, Gulani V, Seiberlich N, Liu K, Sunshine JL, Duerk JL, Griswold MA (2013 Mar 14) Magnetic resonance fingerprinting. Nature 495(7440):187–192CrossRefPubMedPubMedCentral Ma D, Gulani V, Seiberlich N, Liu K, Sunshine JL, Duerk JL, Griswold MA (2013 Mar 14) Magnetic resonance fingerprinting. Nature 495(7440):187–192CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat McGill LA, Ferreira PF, Scott AD, Nielles-Vallespin S, Giannakidis A, Kilner PJ et al (2016 Jan 6) Relationship between cardiac diffusion tensor imaging parameters and anthropometrics in healthy volunteers. J Cardiovasc Magn Reson 18:2CrossRefPubMedPubMedCentral McGill LA, Ferreira PF, Scott AD, Nielles-Vallespin S, Giannakidis A, Kilner PJ et al (2016 Jan 6) Relationship between cardiac diffusion tensor imaging parameters and anthropometrics in healthy volunteers. J Cardiovasc Magn Reson 18:2CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Moseley ME, Cohen Y, Kucharczyk J, Mintorovitch J, Asgari HS, Wendland MF, Tsuruda J, Norman D (1990) Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system. Radiology 176(2):439–445CrossRefPubMed Moseley ME, Cohen Y, Kucharczyk J, Mintorovitch J, Asgari HS, Wendland MF, Tsuruda J, Norman D (1990) Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system. Radiology 176(2):439–445CrossRefPubMed
22.
Zurück zum Zitat Kerckhoffs RCP, Bovendeerd P, Prinzen F, Smits K, Arts T (2003) Intra-and interventricular asynchrony of electromechanics in the ventricularly paced heart. J Eng Math 47:201–216CrossRef Kerckhoffs RCP, Bovendeerd P, Prinzen F, Smits K, Arts T (2003) Intra-and interventricular asynchrony of electromechanics in the ventricularly paced heart. J Eng Math 47:201–216CrossRef
23.
Zurück zum Zitat Niederer SA, Plank G, Chinchapatnam P, Ginks M, Lamata P, Rhode KS, Rinaldi CA, Razavi R, Smith NP (2011) Length-dependent tension in the failing heart and the efficacy of cardiac resynchronization therapy. Cardiovasc Res 89:336–343CrossRefPubMed Niederer SA, Plank G, Chinchapatnam P, Ginks M, Lamata P, Rhode KS, Rinaldi CA, Razavi R, Smith NP (2011) Length-dependent tension in the failing heart and the efficacy of cardiac resynchronization therapy. Cardiovasc Res 89:336–343CrossRefPubMed
24.
Zurück zum Zitat Von Deuster C, Sammut E, Asner L, Nordsletten D, Lamata P, Stoeck CT, et al. Studying dynamic myofiber aggregate reorientation in dilated cardiomyopathy using in vivo magnetic resonance diffusion tensor imaging. Circ Cardiovasc Imaging. 2016; Oct; 9(10): e005018 Von Deuster C, Sammut E, Asner L, Nordsletten D, Lamata P, Stoeck CT, et al. Studying dynamic myofiber aggregate reorientation in dilated cardiomyopathy using in vivo magnetic resonance diffusion tensor imaging. Circ Cardiovasc Imaging. 2016; Oct; 9(10): e005018
25.
Zurück zum Zitat Rutty GN, Morgan B, O'Donnell C, Leth PM, Thali M (2008) Forensic institutes across the world place CT or MRI scanners or both into their mortuaries. J Trauma 65:493–494CrossRefPubMed Rutty GN, Morgan B, O'Donnell C, Leth PM, Thali M (2008) Forensic institutes across the world place CT or MRI scanners or both into their mortuaries. J Trauma 65:493–494CrossRefPubMed
26.
Zurück zum Zitat Baglivo M, Winklhofer S, Hatch GM, Ampanozi G, Thali MJ, Ruder TD (2013) The rise of forensic and post-mortem radiology—analysis of the literature between the years 2000 and 2011. J Forensic Radiol Imaging 1:3–9CrossRef Baglivo M, Winklhofer S, Hatch GM, Ampanozi G, Thali MJ, Ruder TD (2013) The rise of forensic and post-mortem radiology—analysis of the literature between the years 2000 and 2011. J Forensic Radiol Imaging 1:3–9CrossRef
27.
Zurück zum Zitat Ruder TD (2013) What are the key objectives of the ISFRI?—evaluation of the ISFRI member survey. J Forensic Radiol Imaging 1(3):142–145CrossRef Ruder TD (2013) What are the key objectives of the ISFRI?—evaluation of the ISFRI member survey. J Forensic Radiol Imaging 1(3):142–145CrossRef
28.
Zurück zum Zitat Jackowski C, Hofmann K, Schwendener N, Schweitzer W, Keller-Sutter M (2011) Coronary thrombus and peracute myocardial infarction visualized by unenhanced postmortem CMR prior to autopsy. Forensic Sci Int 214:e16–e19CrossRefPubMed Jackowski C, Hofmann K, Schwendener N, Schweitzer W, Keller-Sutter M (2011) Coronary thrombus and peracute myocardial infarction visualized by unenhanced postmortem CMR prior to autopsy. Forensic Sci Int 214:e16–e19CrossRefPubMed
29.
Zurück zum Zitat Jackowski C, thesis “Macroscopical and histological findings in comparison with CT- and MRI examinations of isolated autopsy hearts.” Institute of Forensic Medicine, O.-v.-G.-University of Magdeburg, Prof. D. Krause, 2003 Jackowski C, thesis “Macroscopical and histological findings in comparison with CT- and MRI examinations of isolated autopsy hearts.” Institute of Forensic Medicine, O.-v.-G.-University of Magdeburg, Prof. D. Krause, 2003
30.
Zurück zum Zitat Ruder TD, Ebert LC, Khattab AA, Rieben R, Thali MJ, Kamat P (2013) Edema is a sign of early acute myocardial infarction on post-mortem magnetic resonance imaging. Forensci Sci Med Pathol 9(4):501–505CrossRef Ruder TD, Ebert LC, Khattab AA, Rieben R, Thali MJ, Kamat P (2013) Edema is a sign of early acute myocardial infarction on post-mortem magnetic resonance imaging. Forensci Sci Med Pathol 9(4):501–505CrossRef
31.
Zurück zum Zitat Holmes AA, Scollan DF, Winslow RL (2000 Jul) Direct histological validation of diffusion tensor MRI in formaldehyde-fixed myocardium. Magn Reson Med 44(1):157–161CrossRefPubMed Holmes AA, Scollan DF, Winslow RL (2000 Jul) Direct histological validation of diffusion tensor MRI in formaldehyde-fixed myocardium. Magn Reson Med 44(1):157–161CrossRefPubMed
32.
Zurück zum Zitat Zech WD, Schwendener N, Persson A, Warntjes MJ, Jackowski C (2015) Temperature dependence of postmortem MR quantification for soft tissue discrimination. Eur Radiol 25:2381–2389CrossRefPubMed Zech WD, Schwendener N, Persson A, Warntjes MJ, Jackowski C (2015) Temperature dependence of postmortem MR quantification for soft tissue discrimination. Eur Radiol 25:2381–2389CrossRefPubMed
33.
Zurück zum Zitat Adolphi N, Gerrard Ch, Hatch G, Takacs N, Nolte K. Determining the temperature-dependence of tissue relaxation times (T1 and T2) for prospective optimization of post-mortem magnetic resonance (PMCMR) image contrast. J Forensic Radiol Imaging 2013; 1: 80 Adolphi N, Gerrard Ch, Hatch G, Takacs N, Nolte K. Determining the temperature-dependence of tissue relaxation times (T1 and T2) for prospective optimization of post-mortem magnetic resonance (PMCMR) image contrast. J Forensic Radiol Imaging 2013; 1: 80
34.
Zurück zum Zitat Ruder TD, Hatch GM, Siegenthaler L, Ampanozi G, Mathier S, Thali MJ, Weber OM (2012) The influence of body temperature on image contrast in post mortem CMR. Eur J Radiol 81:1366–1370CrossRefPubMed Ruder TD, Hatch GM, Siegenthaler L, Ampanozi G, Mathier S, Thali MJ, Weber OM (2012) The influence of body temperature on image contrast in post mortem CMR. Eur J Radiol 81:1366–1370CrossRefPubMed
35.
Zurück zum Zitat Ruder D, Thali M, Hatch GM (2014) Forensic radiology special feature: review article, essential of forensic post-mortem MR imaging in adults. Br J Radiol 87(1036):20130567CrossRefPubMedPubMedCentral Ruder D, Thali M, Hatch GM (2014) Forensic radiology special feature: review article, essential of forensic post-mortem MR imaging in adults. Br J Radiol 87(1036):20130567CrossRefPubMedPubMedCentral
36.
Zurück zum Zitat Jackowski C, Thali M, Aghayev E, Yen K, Sonnenschein M, Zwygart K et al (2005) Postmortem imaging of blood and its characteristics using MSCT and MRI. Int J Legal Med (4):1–8 Jackowski C, Thali M, Aghayev E, Yen K, Sonnenschein M, Zwygart K et al (2005) Postmortem imaging of blood and its characteristics using MSCT and MRI. Int J Legal Med (4):1–8
37.
38.
Zurück zum Zitat Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R et al (2017) Heart disease and stroke statistics–2017 update: a report from the American Heart Association. Circulation:135 Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R et al (2017) Heart disease and stroke statistics–2017 update: a report from the American Heart Association. Circulation:135
39.
Zurück zum Zitat Srikanth S, Ambrose JA (2012) Pathophysiology of coronary thrombus formation and adverse consequences of thrombus during PCI. Current Card Rev 8:168–176CrossRef Srikanth S, Ambrose JA (2012) Pathophysiology of coronary thrombus formation and adverse consequences of thrombus during PCI. Current Card Rev 8:168–176CrossRef
40.
Zurück zum Zitat Jackowski C, Christe A, Sonnenschein M, Aghayev E, Thali MJ (2006) Postmortem unenhanced magnetic resonance imaging of myocardial infarction in correlation to histological infarction age characterization. Eur Heart J 27:2459–2467CrossRefPubMed Jackowski C, Christe A, Sonnenschein M, Aghayev E, Thali MJ (2006) Postmortem unenhanced magnetic resonance imaging of myocardial infarction in correlation to histological infarction age characterization. Eur Heart J 27:2459–2467CrossRefPubMed
41.
Zurück zum Zitat Jackowski C, Warntjes MJ, Berge J, Bӓr W, Persson A (2011) Magnetic resonance imaging goes postmortem: noninvasive detection and assessment of myocardial infarction by postmortem CMR. Eur Radiol 21:70–78CrossRefPubMed Jackowski C, Warntjes MJ, Berge J, Bӓr W, Persson A (2011) Magnetic resonance imaging goes postmortem: noninvasive detection and assessment of myocardial infarction by postmortem CMR. Eur Radiol 21:70–78CrossRefPubMed
42.
Zurück zum Zitat Jackowski C, Schwendener N, Grabherr S, Persson A (2013) Post-mortem cardiac 3-T magnetic resonance imaging: visualization of sudden cardiac death? J Am Coll Cardiol 62(7):617–629CrossRefPubMed Jackowski C, Schwendener N, Grabherr S, Persson A (2013) Post-mortem cardiac 3-T magnetic resonance imaging: visualization of sudden cardiac death? J Am Coll Cardiol 62(7):617–629CrossRefPubMed
43.
Zurück zum Zitat Abdel-Aty H, Cocker M, Meek C, Tyberg JV, Friedrich MG (2009) Edema as a very early marker for acute myocardial ischemia: a cardiovascular magnetic resonance study. J Am Coll Cardiol 53:1194–1201CrossRefPubMed Abdel-Aty H, Cocker M, Meek C, Tyberg JV, Friedrich MG (2009) Edema as a very early marker for acute myocardial ischemia: a cardiovascular magnetic resonance study. J Am Coll Cardiol 53:1194–1201CrossRefPubMed
44.
Zurück zum Zitat Winklhofer S, Stoeck CT, Berger N, Thali M, Manka R, Kozerke S, Alkadhi H, Stolzmann P (2014) Post-mortem cardiac diffusion tensor imaging: detection of myocardial infarction and remodeling of myofiber architecture. Eur Radiol 24(11):2810–2818CrossRefPubMed Winklhofer S, Stoeck CT, Berger N, Thali M, Manka R, Kozerke S, Alkadhi H, Stolzmann P (2014) Post-mortem cardiac diffusion tensor imaging: detection of myocardial infarction and remodeling of myofiber architecture. Eur Radiol 24(11):2810–2818CrossRefPubMed
45.
Zurück zum Zitat Schwendener N, Jackowski C, Persson A, Warntjes MJ, Schuster F, Riva F, Zech WD (2017) Detection of early acute and following age stages of myocardial infarction with quantitative post-mortem cardiac 1,5T MR. Forensic Sci Int 270:248–254CrossRefPubMed Schwendener N, Jackowski C, Persson A, Warntjes MJ, Schuster F, Riva F, Zech WD (2017) Detection of early acute and following age stages of myocardial infarction with quantitative post-mortem cardiac 1,5T MR. Forensic Sci Int 270:248–254CrossRefPubMed
46.
Zurück zum Zitat Huda W, Slone R. Magnetic resonance. In: Huda W, Slone R, editor, eds. Review of radiologic physics. Philadelphia, PA: Lippincott Williams & Wilkins; 2003. pp. 192–221 Huda W, Slone R. Magnetic resonance. In: Huda W, Slone R, editor, eds. Review of radiologic physics. Philadelphia, PA: Lippincott Williams & Wilkins; 2003. pp. 192–221
47.
Zurück zum Zitat Ruder TD, Bauer-Kreutz R, Ampanozi G, Rosskopf AB, Pilgrim TM, Weber OM, Thali MJ, Hatch GM (2012) Assessment of coronary artery disease by post-mortem cardiac MR. Eur J Radiol 81:2208–2214CrossRefPubMed Ruder TD, Bauer-Kreutz R, Ampanozi G, Rosskopf AB, Pilgrim TM, Weber OM, Thali MJ, Hatch GM (2012) Assessment of coronary artery disease by post-mortem cardiac MR. Eur J Radiol 81:2208–2214CrossRefPubMed
48.
Zurück zum Zitat Varnava AM, Elliott PM, Baboonian C, Davison F, Davies MJ, McKenna WJ (2001) Hypertrophic cardiomyopathy: histopathological features of sudden death in cardiac troponin T disease. Circulation 104:1380–1384CrossRefPubMed Varnava AM, Elliott PM, Baboonian C, Davison F, Davies MJ, McKenna WJ (2001) Hypertrophic cardiomyopathy: histopathological features of sudden death in cardiac troponin T disease. Circulation 104:1380–1384CrossRefPubMed
49.
Zurück zum Zitat Basso C, Thiene G, Corrado D, Buja G, Melacini P, Nava A (2000) Hypertrophic cardiomyopathy and sudden death in the young: pathologic evidence of myocardial ischemia. Hum Pathol 31:988–998CrossRefPubMed Basso C, Thiene G, Corrado D, Buja G, Melacini P, Nava A (2000) Hypertrophic cardiomyopathy and sudden death in the young: pathologic evidence of myocardial ischemia. Hum Pathol 31:988–998CrossRefPubMed
50.
Zurück zum Zitat Josephson ME (2002) Recurrent ventricular tachycardias M.E. Josephson (Ed.), Clinical cardiac electrophysiology, Lippincott Williams & Wilkins, Philadelphia, PA, p. 433–445 Josephson ME (2002) Recurrent ventricular tachycardias M.E. Josephson (Ed.), Clinical cardiac electrophysiology, Lippincott Williams & Wilkins, Philadelphia, PA, p. 433–445
51.
Zurück zum Zitat Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW (2011) 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 124(24):2761–2796CrossRefPubMed Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW (2011) 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 124(24):2761–2796CrossRefPubMed
53.
Zurück zum Zitat O'Hanlon R, Assomull RG, Prasad SK (2007) Use of cardiovascular magnetic resonance for diagnosis and management in hypertrophic cardiomyopathy. Curr Cardiol Rep 9:51–56CrossRefPubMed O'Hanlon R, Assomull RG, Prasad SK (2007) Use of cardiovascular magnetic resonance for diagnosis and management in hypertrophic cardiomyopathy. Curr Cardiol Rep 9:51–56CrossRefPubMed
54.
Zurück zum Zitat Reichek N, Gupta D (2008) Hypertrophic cardiomyopathy: cardiac magnetic resonance imaging changes the paradigm. J Am Coll Cardiol 52:567–568CrossRefPubMed Reichek N, Gupta D (2008) Hypertrophic cardiomyopathy: cardiac magnetic resonance imaging changes the paradigm. J Am Coll Cardiol 52:567–568CrossRefPubMed
55.
Zurück zum Zitat Jackowski C, Schweitzer W, Thali M, Yen K, Aghayev E, Sonnenschein M, Vock P, Dirnhofer R (2005) Virtopsy: postmortem imaging of the human heart in situ using MSCT and CMR. Forensic Sci Int 149(1):11–23CrossRefPubMed Jackowski C, Schweitzer W, Thali M, Yen K, Aghayev E, Sonnenschein M, Vock P, Dirnhofer R (2005) Virtopsy: postmortem imaging of the human heart in situ using MSCT and CMR. Forensic Sci Int 149(1):11–23CrossRefPubMed
56.
Zurück zum Zitat Todiere G, Pisciella L, Barison A, Del Franco A, Zachara E, Piaggi P et al (2014) Abnormal T2-STIR magnetic resonance in hypertrophic cardiomyopathy: a marker of advanced disease and electrical myocardial instability. PLoS One 9(10):e111366CrossRefPubMedPubMedCentral Todiere G, Pisciella L, Barison A, Del Franco A, Zachara E, Piaggi P et al (2014) Abnormal T2-STIR magnetic resonance in hypertrophic cardiomyopathy: a marker of advanced disease and electrical myocardial instability. PLoS One 9(10):e111366CrossRefPubMedPubMedCentral
57.
Zurück zum Zitat Hen Y, Iguchi N, Machida H, Takada K, Utanohara Y, Sumiyoshi T (2013) High signal intensity on T2-weighted cardiac magnetic resonance imaging correlates with the ventricular tachyarrhythmia in hypertrophic cardiomyopathy. Heart Vessel 28(6):742–749CrossRef Hen Y, Iguchi N, Machida H, Takada K, Utanohara Y, Sumiyoshi T (2013) High signal intensity on T2-weighted cardiac magnetic resonance imaging correlates with the ventricular tachyarrhythmia in hypertrophic cardiomyopathy. Heart Vessel 28(6):742–749CrossRef
58.
Zurück zum Zitat Sen-Chowdhry S, Morgan RD, Chambers JC, McKenna WJ (2010) Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment. Annu Rev Med 61:233–253CrossRefPubMed Sen-Chowdhry S, Morgan RD, Chambers JC, McKenna WJ (2010) Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment. Annu Rev Med 61:233–253CrossRefPubMed
59.
Zurück zum Zitat Dalal D, Nasir K, Bomma C, Prakasa K, Tandri H, Piccini J, Roguin A, Tichnell C, James C, Russell SD, Judge DP, Abraham T, Spevak PJ, Bluemke DA, Calkins H (2005) Arrhythmogenic right ventricular dysplasia a United States experience. Circulation 112:3823–3832CrossRefPubMed Dalal D, Nasir K, Bomma C, Prakasa K, Tandri H, Piccini J, Roguin A, Tichnell C, James C, Russell SD, Judge DP, Abraham T, Spevak PJ, Bluemke DA, Calkins H (2005) Arrhythmogenic right ventricular dysplasia a United States experience. Circulation 112:3823–3832CrossRefPubMed
60.
Zurück zum Zitat Te Riele AS, James CA, Philips B, Rastegar N, Bhonsale A, Groeneweg JA et al (2013) Mutation-positive arrhythmogenic right ventricular dysplasia/cardiomyopathy: the triangle of dysplasia displaced. J Cardiovasc Electrophysiol 24:1311–1320CrossRef Te Riele AS, James CA, Philips B, Rastegar N, Bhonsale A, Groeneweg JA et al (2013) Mutation-positive arrhythmogenic right ventricular dysplasia/cardiomyopathy: the triangle of dysplasia displaced. J Cardiovasc Electrophysiol 24:1311–1320CrossRef
61.
Zurück zum Zitat Basso C, Corrado D, Marcus FI, Nava A, Thiene G (2009) Arrhythmogenic right ventricular cardiomyopathy. Lancet 373(9671):1289–1300CrossRefPubMed Basso C, Corrado D, Marcus FI, Nava A, Thiene G (2009) Arrhythmogenic right ventricular cardiomyopathy. Lancet 373(9671):1289–1300CrossRefPubMed
62.
Zurück zum Zitat Aquaro GD, Nucifora G, Pederzoli L, Strata E, De Marchi D, Todiere G et al (2012) Fat in left ventricular myocardium assessed by steady-state free precession pulse sequences. Int J Cardiovasc Imaging 28(4):813–821CrossRefPubMed Aquaro GD, Nucifora G, Pederzoli L, Strata E, De Marchi D, Todiere G et al (2012) Fat in left ventricular myocardium assessed by steady-state free precession pulse sequences. Int J Cardiovasc Imaging 28(4):813–821CrossRefPubMed
63.
Zurück zum Zitat Aquaro GD, Todiere G, Strata E, Barison A, Di Bella G, Lombardi M (2014) Usefulness of India ink artifact in steady-state free precession pulse sequences for detection and quantification of intramyocardial fat. J Magn Reson Imaging 40(1):126–132CrossRefPubMed Aquaro GD, Todiere G, Strata E, Barison A, Di Bella G, Lombardi M (2014) Usefulness of India ink artifact in steady-state free precession pulse sequences for detection and quantification of intramyocardial fat. J Magn Reson Imaging 40(1):126–132CrossRefPubMed
64.
Zurück zum Zitat Puranik R, Gray B, Lackey H, Yeates L, Parker G, Duflou J, Semsarian C (2014) Comparison of conventional autopsy and magnetic resonance imaging in determining the cause of sudden death in the young. J Cardiovasc Magn Reson 16(1):44CrossRefPubMedPubMedCentral Puranik R, Gray B, Lackey H, Yeates L, Parker G, Duflou J, Semsarian C (2014) Comparison of conventional autopsy and magnetic resonance imaging in determining the cause of sudden death in the young. J Cardiovasc Magn Reson 16(1):44CrossRefPubMedPubMedCentral
65.
Zurück zum Zitat Fabre A, Sheppard MN (2006) Sudden adult death syndrome and other non-ischaemic causes of sudden cardiac death. Heart 92:316–320CrossRefPubMed Fabre A, Sheppard MN (2006) Sudden adult death syndrome and other non-ischaemic causes of sudden cardiac death. Heart 92:316–320CrossRefPubMed
66.
Zurück zum Zitat Puranik R, Chow CK, Duflou JA, Kilborn MJ, McGuire MA (2005) Sudden death in the young. Heart Rhythm 2:1277–1282CrossRefPubMed Puranik R, Chow CK, Duflou JA, Kilborn MJ, McGuire MA (2005) Sudden death in the young. Heart Rhythm 2:1277–1282CrossRefPubMed
67.
Zurück zum Zitat Aquaro GD, Del Franco A, Meini M, Gabutti A, Barison A, Chiappino D et al (2014) Cocaine assumption and transient myocardial edema in asymptomatic cocaine heavy-users. Int J Cardiol 173:614–615CrossRefPubMed Aquaro GD, Del Franco A, Meini M, Gabutti A, Barison A, Chiappino D et al (2014) Cocaine assumption and transient myocardial edema in asymptomatic cocaine heavy-users. Int J Cardiol 173:614–615CrossRefPubMed
68.
Zurück zum Zitat Di Paolo M, Aimo A, Barison A, Aquaro GD, Roas L, Emdin M (2016) The heart after idarubicin overdose. Cardiac death in a patient with acute promyelocitic leukaemia. Int J Cardiol 203:997–999CrossRefPubMed Di Paolo M, Aimo A, Barison A, Aquaro GD, Roas L, Emdin M (2016) The heart after idarubicin overdose. Cardiac death in a patient with acute promyelocitic leukaemia. Int J Cardiol 203:997–999CrossRefPubMed
69.
Zurück zum Zitat Selvanayagam JB, Hawkins PN, Paul B, Myerson SG, Neubauer S. Evaluation and management of the cardiac amyloidosis. J Am Coll Cardiol 2007;50:2101–2110 Selvanayagam JB, Hawkins PN, Paul B, Myerson SG, Neubauer S. Evaluation and management of the cardiac amyloidosis. J Am Coll Cardiol 2007;50:2101–2110
70.
Zurück zum Zitat Dubrey SW, Hawkins PN, Falk RH (2011) Amyloid diseases of the heart: assessment, diagnosis, and referral. Heart 97:75–84CrossRefPubMed Dubrey SW, Hawkins PN, Falk RH (2011) Amyloid diseases of the heart: assessment, diagnosis, and referral. Heart 97:75–84CrossRefPubMed
Metadaten
Titel
Postmortem cardiac magnetic resonance in sudden cardiac death
verfasst von
Benedetta Guidi
Giovanni Donato Aquaro
Marco Gesi
Michele Emdin
Marco Di Paolo
Publikationsdatum
04.05.2018
Verlag
Springer US
Erschienen in
Heart Failure Reviews / Ausgabe 5/2018
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-018-9705-0

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