Die allergenspezifische Immuntherapie

Zurück zum Zitat Durham SR, Leung DY. One hundred years of allergen immunotherapy: time to ring the chang-es. J Allergy Clin Immunol 2011;127:3-7 Durham SR, Leung DY. One hundred years of allergen immunotherapy: time to ring the chang-es. J Allergy Clin Immunol 2011;127:3-7

Zurück zum Zitat Pfaar O, Bachert C, Bufe A, Buhl R, Ebner C, Eng P et al. Guideline on allergen specific immunotherapy in IgE mediated allergic diseases: S2k Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Society for Pediatric Allergy and Environmental Medicine (GPA), the Medical Association of German Allergologists (AeDA), the Austrian Society for Allergy and Immunology (ÖGAI), the Swiss Society for Allergy and Immunology (SGAI), the German Society of Dermatology (DDG), the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (DGHNO-KHC), the German Society of Pediatrics and Adolescent Medicine (DGKJ), the Society for Pediatric Pneumology (GPP), the German Respiratory Society (DGP), the German Association of ENT Surgeons (BV-HNO), the Professional Federation of Paediatricians and Youth Doctors (BVKJ), the Federal Association of Pulmonologists (BDP) and the German Dermatologists Association (BVDD). Allergo J Int 2014;23:282-319 Pfaar O, Bachert C, Bufe A, Buhl R, Ebner C, Eng P et al. Guideline on allergen specific immunotherapy in IgE mediated allergic diseases: S2k Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Society for Pediatric Allergy and Environmental Medicine (GPA), the Medical Association of German Allergologists (AeDA), the Austrian Society for Allergy and Immunology (ÖGAI), the Swiss Society for Allergy and Immunology (SGAI), the German Society of Dermatology (DDG), the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (DGHNO-KHC), the German Society of Pediatrics and Adolescent Medicine (DGKJ), the Society for Pediatric Pneumology (GPP), the German Respiratory Society (DGP), the German Association of ENT Surgeons (BV-HNO), the Professional Federation of Paediatricians and Youth Doctors (BVKJ), the Federal Association of Pulmonologists (BDP) and the German Dermatologists Association (BVDD). Allergo J Int 2014;23:282-319

Zurück zum Zitat Roberts G, Pfaar O, Akdis CA, Ansotegui IJ, Durham SR, van Wijk RG et al. EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis. Allergy 2018;73:765-98 Roberts G, Pfaar O, Akdis CA, Ansotegui IJ, Durham SR, van Wijk RG et al. EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis. Allergy 2018;73:765-98

Zurück zum Zitat 11. Jutel M, Agache I, Bonini S, Burks AW, Calderon M, Canonica W et al. International Consensus on Allergen Immunotherapy II: Mechanisms, standardization, and pharmacoeconomics. J Allergy Clin Immunol 2016;137:358-68 11. Jutel M, Agache I, Bonini S, Burks AW, Calderon M, Canonica W et al. International Consensus on Allergen Immunotherapy II: Mechanisms, standardization, and pharmacoeconomics. J Allergy Clin Immunol 2016;137:358-68

Zurück zum Zitat Shamji MH, Durham SR. Mechanisms of allergen immunotherapy for inhaled allergens and predic-tive biomarkers. J Allergy Clin Immunol 2017;140:1485-98 Shamji MH, Durham SR. Mechanisms of allergen immunotherapy for inhaled allergens and predic-tive biomarkers. J Allergy Clin Immunol 2017;140:1485-98

Zurück zum Zitat Durham SR, Walker SM, Varga EM, Jacobson MR, O'Brien F, Noble W et al. Long-term clinical efficacy of grass-pollen immunotherapy. N Engl J Med 1999;341:468-75 Durham SR, Walker SM, Varga EM, Jacobson MR, O'Brien F, Noble W et al. Long-term clinical efficacy of grass-pollen immunotherapy. N Engl J Med 1999;341:468-75

Zurück zum Zitat Durham SR, Emminger W, Kapp A, de Monchy JGR, Rak S, Scadding GK et al. SQ-standardized sublingual grass immunotherapy: confirmation of disease modification 2 years after 3 years of treatment in a randomized trial. J Allergy Clin Immunol 2012;129:717-25 e5 Durham SR, Emminger W, Kapp A, de Monchy JGR, Rak S, Scadding GK et al. SQ-standardized sublingual grass immunotherapy: confirmation of disease modification 2 years after 3 years of treatment in a randomized trial. J Allergy Clin Immunol 2012;129:717-25 e5

Zurück zum Zitat Muraro A, Roberts G (eds). Allergen Immunotherapy Guidelines Part 1: Systematic reviews. Zurich: European Academy of Allergy and Clinical Immunology (EAACI), 2017 Muraro A, Roberts G (eds). Allergen Immunotherapy Guidelines Part 1: Systematic reviews. Zurich: European Academy of Allergy and Clinical Immunology (EAACI), 2017

Zurück zum Zitat European Medicines Agency. Committee for Medicinal Products for Human Use (CHMP). Guideline on the clinical development of products for specific immunotherapy for the treatment of allergic diseases, 2008 (CHMP/EWP/18504/ 2006). www.ema.europa.eu/docs/en_GB/document_library/Scientific_guide-line/2009/09/WC500003605.pdf. European Medicines Agency. Committee for Medicinal Products for Human Use (CHMP). Guideline on the clinical development of products for specific immunotherapy for the treatment of allergic diseases, 2008 (CHMP/EWP/18504/ 2006). www.​ema.​europa.​eu/​docs/​en_​GB/​document_​library/​Scientific_​guide-line/​2009/​09/​WC500003605.​pdf.

Zurück zum Zitat Pfaar O, Demoly P, Gerth van Wijk R, Bonini S, Bousquet J, Canonica GW et al; European Academy of Allergy and Clinical Immunology. Recommendations for the stand-ardization of clinical outcomes used in allergen immunotherapy trials for allergic rhinoconjunc-tivitis: an EAACI Position Paper. Allergy 2014;69:854-67 Pfaar O, Demoly P, Gerth van Wijk R, Bonini S, Bousquet J, Canonica GW et al; European Academy of Allergy and Clinical Immunology. Recommendations for the stand-ardization of clinical outcomes used in allergen immunotherapy trials for allergic rhinoconjunc-tivitis: an EAACI Position Paper. Allergy 2014;69:854-67

Zurück zum Zitat Dhami S, Kakourou A, Asamoah F, Agache I, Lau S, Jutel M et al. Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis. Allergy 2017;72:1825-48 Dhami S, Kakourou A, Asamoah F, Agache I, Lau S, Jutel M et al. Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis. Allergy 2017;72:1825-48

Zurück zum Zitat Dhami S, Nurmatov U, Arasi S, Khan T, Asaria M, Zaman H et al. Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis. Allergy 2017;72:1597-631 Dhami S, Nurmatov U, Arasi S, Khan T, Asaria M, Zaman H et al. Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis. Allergy 2017;72:1597-631

Zurück zum Zitat Kristiansen M, Dhami S, Netuveli G, Halken S, Muraro A, Roberts G et al. Allergen immunotherapy for the prevention of allergy: A systematic review and meta-analysis. Pediatr Allergy Immunol 2017;28:18-29 Kristiansen M, Dhami S, Netuveli G, Halken S, Muraro A, Roberts G et al. Allergen immunotherapy for the prevention of allergy: A systematic review and meta-analysis. Pediatr Allergy Immunol 2017;28:18-29

Zurück zum Zitat Asaria M, Dhami S, van Ree R, van Wijk G, Muraro A, Roberts G et al. Health economic analysis of allergen immunotherapy for the management of allergic rhinitis, asthma, food allergy and venom allergy: A systematic overview. Allergy 2018;73:269-83 Asaria M, Dhami S, van Ree R, van Wijk G, Muraro A, Roberts G et al. Health economic analysis of allergen immunotherapy for the management of allergic rhinitis, asthma, food allergy and venom allergy: A systematic overview. Allergy 2018;73:269-83

Zurück zum Zitat European Medicines Agency. Committee for Medicinal Products for Human Use (CHMP). Guideline on allergen Products: production and quality issues, 2008 (EMEA/CHMP/BWP/ 304831/2007). www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003333.pdf European Medicines Agency. Committee for Medicinal Products for Human Use (CHMP). Guideline on allergen Products: production and quality issues, 2008 (EMEA/CHMP/BWP/ 304831/2007). www.​ema.​europa.​eu/​docs/​en_​GB/​document_​library/​Scientific_​guideline/​2009/​09/​WC500003333.​pdf

Zurück zum Zitat Englert S, May S, Kaul S, Vieths S. Die Therapieallergene-Verordnung. Hintergrund und Auswirkungen. Bundesgesundheitsbl 2012;55:351-7 Englert S, May S, Kaul S, Vieths S. Die Therapieallergene-Verordnung. Hintergrund und Auswirkungen. Bundesgesundheitsbl 2012;55:351-7

Zurück zum Zitat Durham SR, Creticos PS, Nelson HS, Li Z, Kaur A, Meltzer EO et al.Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses. J Allergy Clin Immunol 2016;138:1081-18e4 Durham SR, Creticos PS, Nelson HS, Li Z, Kaur A, Meltzer EO et al.Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses. J Allergy Clin Immunol 2016;138:1081-18e4

Zurück zum Zitat Shamji MH, Kappen JH, Akdis M, Jensen-Jarolim E, Knol EF, Kleine-Tebbe J et al. Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper. Allergy 2017; 72:1156-73 Shamji MH, Kappen JH, Akdis M, Jensen-Jarolim E, Knol EF, Kleine-Tebbe J et al. Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper. Allergy 2017; 72:1156-73

Zurück zum Zitat Jutel M, Agache I, Bonini S, Burks AW, Calderon M, Canonica W et al. International consensus on allergy immunotherapy. J Allergy Clin Immunol 2015;136:556-68 Jutel M, Agache I, Bonini S, Burks AW, Calderon M, Canonica W et al. International consensus on allergy immunotherapy. J Allergy Clin Immunol 2015;136:556-68

Zurück zum Zitat Meadows A, Kaambwa B, Novielli N, Huissoon A, Fry-Smith A, Meads C et al. A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis. Health Technol Assess 2013;17:vi, xi-xiv, 1-322 Meadows A, Kaambwa B, Novielli N, Huissoon A, Fry-Smith A, Meads C et al. A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis. Health Technol Assess 2013;17:vi, xi-xiv, 1-322

Zurück zum Zitat Schmitt J, Stadler E, Kuster D, Wustenberg EG. Medical care and treatment of allergic rhinitis: a population-based cohort study based on routine healthcare utilization data. Allergy 2016;71:850-8. Schmitt J, Stadler E, Kuster D, Wustenberg EG. Medical care and treatment of allergic rhinitis: a population-based cohort study based on routine healthcare utilization data. Allergy 2016;71:850-8.

Zurück zum Zitat Zielen S, Devillier P, Heinrich J, Richter H, Wahn U. Sublingual immunotherapy provides long-term relief in allergic rhinitis and reduces the risk of asthma: A retrospective, real-world database analysis. Allergy 2018;73:165-77 Zielen S, Devillier P, Heinrich J, Richter H, Wahn U. Sublingual immunotherapy provides long-term relief in allergic rhinitis and reduces the risk of asthma: A retrospective, real-world database analysis. Allergy 2018;73:165-77

Zurück zum Zitat Pfaar O, Bonini S, Cardona V, Demoly P, Jakob T, Jutel M et al. Perspectives in allergen immunotherapy: 2017 and beyond. Allergy 2018;73(Suppl 104):5-23 Pfaar O, Bonini S, Cardona V, Demoly P, Jakob T, Jutel M et al. Perspectives in allergen immunotherapy: 2017 and beyond. Allergy 2018;73(Suppl 104):5-23