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Head and Neck Pathology

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13.02.2019 | Sine qua non Clinicopathologic Correlation

EBV-Associated Non-keratinizing Nasopharyngeal Carcinoma with Prominent Spindled Cell and Whorling Patterns: A Previously Unreported Histological Variant in a Patient Presenting with Dermatomyositis

verfasst von: Fredrik Petersson

Erschienen in: Head and Neck Pathology | Ausgabe 1/2020

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Abstract

A case of non-keratinizing, EBV-positive (chromogenic EBER-in situ hybridization), carcinoma with a hitherto undescribed nodular whorling architecture is presented. The patient is a 55 year old male with 2 months history of dermatomyositis who was diagnosed with T1N0M0 non-keratinizing nasopharyngeal carcinoma. The patient received radiotherapy with complete response. The tumor cells predominantly displayed spindle cell morphology, strongly expressed low-molecular weight cytokeratins (AE1-3), p63 and p40. There was no evidence of recurrence or disease progression on follow-up after 16 months which included post treatment biopsy, MRI and PET-CT scans.

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Titel: EBV-Associated Non-keratinizing Nasopharyngeal Carcinoma with Prominent Spindled Cell and Whorling Patterns: A Previously Unreported Histological Variant in a Patient Presenting with Dermatomyositis
verfasst von: Fredrik Petersson
Publikationsdatum: 13.02.2019
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 1/2020
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-019-01019-z

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

EBV-Associated Non-keratinizing Nasopharyngeal Carcinoma with Prominent Spindled Cell and Whorling Patterns: A Previously Unreported Histological Variant in a Patient Presenting with Dermatomyositis

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

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