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European Journal of Applied Physiology

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01.05.2012 | Original Article

Effects of vibration training on bone metabolism: results from a short-term bed rest study

verfasst von: Natalie Baecker, Petra Frings-Meuthen, Martina Heer, Jochen Mester, Anna-Maria Liphardt

Erschienen in: European Journal of Applied Physiology | Ausgabe 5/2012

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Abstract

The absence of mechanical loading leads to a prompt increase in bone resorption measured by bone resorption markers. There is high potential that vibration training can positively influence bone metabolism in immobilized subjects, reduce the increase in osteoclastic activity and increase bone formation processes. We investigated whether vibration training at 20 Hz with an amplitude of 2–4 mm influences bone metabolism during immobilization. Eight male subjects (26.4 ± 4.9 years; 78.1 ± 9.5 kg) performed a 14 day bed rest in 6°-head down tilt (HDT). Subjects received vibration training for 2 × 5 min/day or a control intervention without vibration (crossover design). Calcium excretion and bone resorption markers C-telopeptide (CTX) and N-telopeptide (NTX) were analyzed from 24 h urine samples. Bone formation markers, bone alkaline phosphatase (bAP) and procollagen-N propeptide (PINP) were analyzed from fasting blood samples. Our results show an increase in bone resorption very early during HDT bed rest in both interventions (CTX: p < 0.01; NTX: p < 0.001). Vibration training did not have any different effect on bone resorption markers (CTX: p = 0.10; NTX: p = 0.58), bone formation markers (PINP: p = 0.21; bAP: p = 0.12) and calcium excretion (p < 0.64) compared to the control condition. Mere vibration training with 20 Hz for 2 × 5 min/day does not prevent increase in bone resorption as measured with the described methods in our short-term HDT bed rest.

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Titel: Effects of vibration training on bone metabolism: results from a short-term bed rest study
verfasst von: Natalie Baecker
Petra Frings-Meuthen
Martina Heer
Jochen Mester
Anna-Maria Liphardt
Publikationsdatum: 01.05.2012
Verlag: Springer-Verlag
Erschienen in: European Journal of Applied Physiology / Ausgabe 5/2012
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-011-2137-3

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