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Current Allergy and Asthma Reports
Erschienen in: Current Allergy and Asthma Reports 5/2017

01.05.2017 | Pediatric Allergy and Immunology (W Dolen, Section Editor)

Emerging Approaches to Food Desensitization in Children

verfasst von: Ahmad Hamad, Wesley A. Burks

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 5/2017

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Abstract

Purpose of Review

The purpose of this review is to highlight the recent advances in food desensitization in children with food allergy.

Recent Findings

Recent advancements in epicutaneous, sublingual, and oral immunotherapy for food allergy in the future may offer children with food allergy and their families a viable option to reduce risk or severity of anaphylaxis with phase III trials ongoing for two of these treatment modalities.

Summary

Food allergy prevalence in children is estimated to be up to 8%. These children are at risk of significant allergic reactions and anaphylaxis. Food avoidance and use of antihistamines or epinephrine has been the standard of care for these patients. This approach also has a significant socioeconomic effects on patients and their families. Recent advancements in understanding food allergy have allowed for exploring new methods of treatment. There is an increasing interest in oral immunotherapy, epicutaneous immunotherapy, or sublingual immunotherapy for food allergy. There have been also innovative approaches to immunotherapy by modification of food allergens (to make them less allergenic while maintain their immunogenicity) or adding adjunctive treatments (probiotics, anti-IgE, etc.) to increase efficacy or safety.
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Metadaten
Titel
Emerging Approaches to Food Desensitization in Children
verfasst von
Ahmad Hamad
Wesley A. Burks
Publikationsdatum
01.05.2017
Verlag
Springer US
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 5/2017
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-017-0700-7

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