nach oben

Graefe's Archive for Clinical and Experimental Ophthalmology

Erschienen in:

16.02.2023 | Review Article

Foldable capsular vitreous body indications, complications, and outcomes: a systematic review

verfasst von: Hashem Abu Serhan, Sara Irshaidat, Leen Abu Serhan, Ayman G. Elnahry

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 8/2023

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Foldable capsular vitreous body (FCVB) is an emerging vitreous substitute that has been recently introduced to treat various advanced vitreoretinal conditions including severe ocular trauma, complicated retinal detachment (RD), and proliferative vitreoretinopathy.

Methods

Review protocol was prospectively registered at PROSPERO (CRD42022342310). A systematic literature search using PubMed, Ovid MEDLINE, and Google Scholar for articles published until May 2022 was performed. The search included the following keywords: foldable capsular vitreous body, FCVB, artificial vitreous substitutes, and artificial vitreous implants. Outcomes included indications of FCVB, anatomical success rates, postoperative intraocular pressure (IOP), best-corrected visual acuity (BCVA), and complications.

Results

A total of 17 studies that utilized FCVB up to May 2022 were included. FCVB was used intraocularly as a tamponade or extraocularly as a macular/scleral buckle for various retinal conditions including severe ocular trauma, simple and complex RD, silicone oil-dependent eyes, and highly myopic eyes with foveoschisis. FCVB was reported to be successfully implanted in the vitreous cavity of all patients. Final retinal reattachment rate ranged from 30 to 100%. Postoperative IOP improved or was maintained in most eyes, with low postoperative complication rates. Improvement in BCVA ranged from 0 to 100% of subjects.

Conclusion

Indications of FCVB implantation have recently widened to include multiple advanced ocular conditions such as complex RD, but also include simpler conditions as uncomplicated RD. FCVB implantation showed good visual and anatomical outcomes, few IOP fluctuations, and a good safety profile. Larger comparative studies are required to further evaluate FCVB implantation.

Nur mit Berechtigung zugänglich

Grus FH, Joachim SC, Pfeiffer N (2007) Proteomics in ocular fluids. Proteomics Clin Appl 1:876–888. https://doi.org/10.1002/prca.200700105CrossRefPubMed

Alovisi C, Panico C, de Sanctis U, Eandi CM (2017) Vitreous substitutes: old and new materials in vitreoretinal surgery. J Ophthalmol 2017:3172138. https://doi.org/10.1155/2017/3172138CrossRefPubMedPubMedCentral

Baino F (2011) Towards an ideal biomaterial for vitreous replacement: historical overview and future trends. Acta Biomater 7:921–935. https://doi.org/10.1016/j.actbio.2010.10.030CrossRefPubMed

Gao Q, Mou S, Ge J, To CH, Hui Y, Liu A, Wang Z, Long C, Tan J (2008) A new strategy to replace the natural vitreous by a novel capsular artificial vitreous body with pressure-control valve. Eye (Lond) 22:461–468. https://doi.org/10.1038/sj.eye.6702875CrossRefPubMed

Wang P, Gao Q, Jiang Z, Lin J, Liu Y, Chen J, Zhou L, Li H, Yang Q, Wang T (2012) Biocompatibility and retinal support of a foldable capsular vitreous body injected with saline or silicone oil implanted in rabbit eyes. Clin Exp Ophthalmol 40:e67-75. https://doi.org/10.1111/j.1442-9071.2011.02664.xCrossRefPubMed

Chen J, Gao Q, Liu Y, Ge J, Cao X, Luo Y, Huang D, Zhou G, Lin S, Lin J, To CH, Siu AW (2011) Clinical device-related article evaluation of morphology and functions of a foldable capsular vitreous body in the rabbit eye. J Biomed Mater Res B Appl Biomater 97:396–404. https://doi.org/10.1002/jbm.b.31812CrossRefPubMed

Feng S, Chen H, Liu Y, Huang Z, Sun X, Zhou L, Lu X, Gao Q (2013) A novel vitreous substitute of using a foldable capsular vitreous body injected with polyvinylalcohol hydrogel. Sci Rep 3:1838. https://doi.org/10.1038/srep01838CrossRefPubMedPubMedCentral

Gao Q, Chen X, Ge J, Liu Y, Jiang Z, Lin Z, Liu Y (2009) Refractive shifts in four selected artificial vitreous substitutes based on Gullstrand-Emsley and Liou-Brennan schematic eyes. Invest Ophthalmol Vis Sci 50:3529–3534. https://doi.org/10.1167/iovs.08-2802CrossRefPubMed

Liu Y, Ke Q, Chen J, Wang Z, Xie Z, Jiang Z, Ge J, Gao Q (2010) Sustained mechanical release of dexamethasone sodium phosphate from a foldable capsular vitreous body. Invest Ophthalmol Vis Sci 51:1636–1642. https://doi.org/10.1167/iovs.09-4134CrossRefPubMed

10.

Lin X, Wang Z, Jiang Z, Long C, Liu Y, Wang P, Jin C, Yi C, Gao Q (2012) Preliminary efficacy and safety of a silicone oil-filled foldable capsular vitreous body in the treatment of severe retinal detachment. Retina 32:729–741. https://doi.org/10.1097/IAE.0b013e31822b1f80CrossRefPubMed

11.

Xu X, Ge H, Li J, Shang W, Ji Y, Yang W, Li K (2021) Outcomes of a foldable capsular vitreous body implantation: a retrospective study. Dis Markers 2021:6575195. https://doi.org/10.1155/2021/6575195CrossRefPubMedPubMedCentral

12.

Chen S, Tian M, Zhang L, Hu C, Liu K, Qin B, Liu S (2021) Reattachment after foldable capsular vitreous body implantation in severe retinal detachment eyes. Transl Vis Sci Technol 10:8. https://doi.org/10.1167/tvst.10.11.8CrossRefPubMedPubMedCentral

13.

Zhang X, Tian X, Zhang B, Guo L, Li X, Jia Y (2019) Study on the effectiveness and safety of foldable capsular vitreous body implantation. BMC Ophthalmol 19:260. https://doi.org/10.1186/s12886-019-1268-xCrossRefPubMedPubMedCentral

14.

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Bmj 372:n71. https://doi.org/10.1136/bmj.n71CrossRefPubMedPubMedCentral

15.

Zhang Z, Liu S, Xie F, Jiang B, Sun M, Sun D (2021) Comparison of viscoelastic Substance injection versus air filling in the anterior chamber during foldable capsular vitreous body (FCVB) implant surgery: a prospective randomized controlled trial. Adv Ther 38:4859–4871. https://doi.org/10.1007/s12325-021-01840-5CrossRefPubMedPubMedCentral

16.

Li M, Tang Y, Li S, Zhang Z, Guan L, Li J, Xu J, Ji S (2022) Foldable capsular vitreous body implantation for complicated retinal detachment caused by severe ocular trauma. Retina 42:1512–1519. https://doi.org/10.1097/iae.0000000000003493CrossRefPubMedPubMedCentral

17.

Lin X, Sun X, Wang Z, Jiang Z, Liu Y, Wang P, Gao Q (2016) Three-year efficacy and safety of a silicone oil-filled foldable-capsular-vitreous-body in three cases of severe retinal detachment. Transl Vis Sci Technol 5:2. https://doi.org/10.1167/tvst.5.1.2CrossRefPubMedPubMedCentral

18.

Zhang C, Xiao R, Wang A, Zhao Z (2022) Silicone oil-filled foldable capsular vitreous body versus silicone oil endotamponade for treatment of no light perception after severe ocular trauma. Retina 42:553–560. https://doi.org/10.1097/iae.0000000000003336CrossRefPubMed

19.

Zhang R, Wang T, Xie C, Lin X, Jiang Z, Wang Z, Liu Y, Luo Y, Long C, He L, Wang P, Gao Q (2011) Evaluation of supporting role of a foldable capsular vitreous body with magnetic resonance imaging in the treatment of severe retinal detachment in human eyes. Eye (Lond) 25:794–802. https://doi.org/10.1038/eye.2011.61CrossRefPubMed

20.

Deng J, Song HP, Zhou RL, Chen T, Wang JZ, Zhu ZL (2021) Evaluation of the long-term effect of foldable capsular vitreous bodies in severe ocular rupture. Int J Ophthalmol 14:1935–1940. https://doi.org/10.18240/ijo.2021.12.19CrossRefPubMedPubMedCentral

21.

Lin X, Ge J, Gao Q, Wang Z, Long C, He L, Liu Y, Jiang Z (2011) Evaluation of the flexibility, efficacy, and safety of a foldable capsular vitreous body in the treatment of severe retinal detachment. Invest Ophthalmol Vis Sci 52:374–381. https://doi.org/10.1167/iovs.10-5869CrossRefPubMed

22.

Wang P, Gao Q, Lin X, Zhang S, Hu J, Liu Y, Xu N, Ge J (2012) Comprehensive analysis of inflammatory immune mediators of the intraocular fluid aspirated from the foldable capsular vitreous body filled-eyes. Plos One 7:e46384. https://doi.org/10.1371/journal.pone.0046384CrossRefPubMedPubMedCentral

23.

Zhang B, Li C, Jia Y, Li X, Guo L, Wang C, Tian X (2020) A pilot clinical study of treating rhegmatogenous retinal detachment by silicone rubber balloon scleral buckling. Retina 40:1918–1928. https://doi.org/10.1097/iae.0000000000002685CrossRefPubMed

24.

Shao Z, Huang C, Zhang Y, Li S, Wang D, Wang Y, Lin H, Sun X, Zhou F, Li J (2022) Psychological effects of foldable capsular vitreous body implantation in patients with impending eye atrophy. Research Square. https://doi.org/10.21203/rs.3.rs-327015/v2

25.

Jiang H, Xue C, Gao Y, Chen Y, Wang Y (2021) Clinical application of foldable capsular vitreous bodies in the treatment of severe ocular trauma and silicone oil dependent eyes. J Ophthalmol 2022:3608162. https://doi.org/10.1155/2022/3608162CrossRef

26.

Liu B, Ma W, Li Y, Luo Y, Jin C, Liang X, Sadda SR, Gao Q, Lu L (2016) Macular buckling using a three-armed silicone capsule for foveoschisis associated with high myopia. Retina 36:1919–1926. https://doi.org/10.1097/iae.0000000000001014CrossRefPubMed

27.

Liu N, Kang L, Yu X, Lv Q, Xi L, Liu M, Liu Y, Wu N (2021) Preliminary clinical application of foldable capsular vitreous body in severe silicone oil-dependent eyes. Ann Palliat Med 10:10922–10929. https://doi.org/10.21037/apm-21-2554CrossRefPubMed

28.

Nishino M, Eguchi H, Iwata A, Shiota H, Tanaka M, Tanaka T (2009) Are topical steroids essential after an uneventful cataract surgery? J Med Invest 56:11–15. https://doi.org/10.2152/jmi.56.11CrossRefPubMed

29.

Bellows AR, Chylack LT, Hutchinson BT (1981) Choroidal detachment: clinical manifestation, therapy and mechanism of formation. Ophthalmology 88:1107–1115. https://doi.org/10.1016/S0161-6420(81)34897-0CrossRefPubMed

30.

Bamonte G, Mura M, Stevie Tan H (2011) Hypotony after 25-gauge vitrectomy. Am J Ophthalmol 151:156–160. https://doi.org/10.1016/j.ajo.2010.06.042CrossRefPubMed

31.

Stefánsson E, Anderson MM Jr, Landers MB 3rd, Tiedeman JS, McCuen BW 2nd (1988) Refractive changes from use of silicone oil in vitreous surgery. Retina 8:20–23. https://doi.org/10.1097/00006982-198808010-00005CrossRefPubMed

Titel: Foldable capsular vitreous body indications, complications, and outcomes: a systematic review
verfasst von: Hashem Abu Serhan
Sara Irshaidat
Leen Abu Serhan
Ayman G. Elnahry
Publikationsdatum: 16.02.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 8/2023
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-023-05995-5

Neu im Fachgebiet Augenheilkunde

Metastase in der periokulären Region

Metastasen Leitthema

Orbitale und periokuläre metastatische Tumoren galten früher als sehr selten. Aber mit der ständigen Aktualisierung von Medikamenten und Nachweismethoden für die Krebsbehandlung werden neue Chemotherapien und Strahlenbehandlungen eingesetzt. Die …

Staging und Systemtherapie bei okulären und periokulären Metastasen

Metastasen Leitthema

Metastasen bösartiger Erkrankungen sind die häufigsten Tumoren, die im Auge diagnostiziert werden. Sie treten bei ungefähr 5–10 % der Patienten mit soliden Tumoren im Verlauf der Erkrankung auf. Besonders häufig sind diese beim Mammakarzinom und …

Wundheilung nach Trabekulektomie

Trabekulektomie CME-Artikel

Die überschießende Wundheilung in der filtrierenden Glaukomchirurgie ist ein zentraler Faktor für ein operatives Versagen. Nach der Einführung der Trabekulektomie in den 1960er-Jahren wurden viele Faktoren erkannt, die mit einer vermehrten …

„standard operating procedures“ (SOP) – Vorschlag zum therapeutischen Management bei periokulären sowie intraokulären Metastasen

Metastasen Leitthema

Peri- sowie intraokuläre Metastasen sind insgesamt gesehen selten und meist Zeichen einer fortgeschrittenen primären Tumorerkrankung. Die Therapie ist daher zumeist palliativ und selten kurativ. Zudem ist die Therapiefindung sehr individuell. Die …

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Foldable capsular vitreous body indications, complications, and outcomes: a systematic review

Abstract

Purpose

Methods

Results

Conclusion

Neu im Fachgebiet Augenheilkunde

Metastase in der periokulären Region

Staging und Systemtherapie bei okulären und periokulären Metastasen

Wundheilung nach Trabekulektomie

„standard operating procedures“ (SOP) – Vorschlag zum therapeutischen Management bei periokulären sowie intraokulären Metastasen

Update Augenheilkunde

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 8/2023

Clinical features and factors affecting prognosis and partial deterioration of ocular papilloma: a retrospective study of 298 cases

Predictive factors for outcomes of half-dose photodynamic therapy combined with aflibercept for pachychoroid neovasculopathy

A rabbit model for outer retinal atrophy caused by surgical RPE removal

Benefit of intravitreal injections in patients with sub-threshold baseline visual acuity: a retrospective single-centre study

Pediatric herpes zoster ophthalmicus: a systematic review

Comparing treatment outcomes in randomized controlled trials of central serous chorioretinopathy

Neu im Fachgebiet Augenheilkunde

Metastase in der periokulären Region

Staging und Systemtherapie bei okulären und periokulären Metastasen

Wundheilung nach Trabekulektomie

„standard operating procedures“ (SOP) – Vorschlag zum therapeutischen Management bei periokulären sowie intraokulären Metastasen

Update Augenheilkunde