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Inflammation Research

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01.01.2010 | Review

Gatekeepers of intestinal inflammation

verfasst von: Heather A. Arnett, Joanne L. Viney

Erschienen in: Inflammation Research | Ausgabe 1/2010

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Abstract

The intestine is subjected to a barrage of insults from food, bacterial flora, and pathogens. Despite this constant antigenic challenge, the mucosal tissues lining the intestinal tract remain largely under control. The mechanisms regulating the homeostatic balance in the gut have been investigated for many years by many groups, but the precise nature of the regulatory control remains elusive. In this review, we provide an overview of pathways proposed to be involved in dampening the inflammatory response and maintaining the homeostatic balance in the intestine, and how these pathways may be disrupted in ulcerative colitis and Crohn’s disease.

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Titel: Gatekeepers of intestinal inflammation
verfasst von: Heather A. Arnett
Joanne L. Viney
Publikationsdatum: 01.01.2010
Verlag: SP Birkhäuser Verlag Basel
Erschienen in: Inflammation Research / Ausgabe 1/2010
Print ISSN: 1023-3830
Elektronische ISSN: 1420-908X
DOI: https://doi.org/10.1007/s00011-009-0091-x

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