Osteoporosis (OP), a systemic skeletal disorder characterized by low bone mineral density and microarchitectural deterioration of bone tissue, affects over 200 million individuals globally [ 1 ]. This leads to an increased fragility of bones.
Osteoporosis is a widespread global systemic skeletal disorder, distinguished by reduced bone mass and increased susceptibility to bone fragility. In cross-sectional research conducted in mainland China, the prevalence of osteoporosis among …
verfasst von:
Yu-Shan Yue, Yang Liu, Ke Lu, Qin Shi, Kai-Xin Zhou, Chong Li
Osteoporosis is a systemic skeletal disorder characterized by decreased bone mass and microarchitectural deterioration, which is a growing concern in an aging population [ 1 ]. Antiresorptive drugs (ARDs), including bisphosphonates and denosumab …
verfasst von:
Catalina Moreno-Rabié, Rocharles Cavalcante Fontenele, Nicolly Oliveira-Santos, Fernanda Nogueira-Reis, Tim Van den Wyngaert, Reinhilde Jacobs
Hip fractures are regarded as the most severe of osteoporotic fractures [ 1 ], and are among the most frequent reasons of admission to hospital and nursing facilities for elderly in western countries [ 2 ]. In a recent review, the total number of …
Individuals who sustain a hip fracture are at high risk for subsequent fractures, and strongly recommended to receive pharmacologic treatment for osteoporosis [ 1 – 4 ]. A number of antiresorptive and anabolic agents have been developed, with a …
verfasst von:
H. Ansari, S. Jaglal, A.M. Cheung, R. Jain, J. Weldon, P. Kurdyak
Patients with myasthenia gravis (MG), because of their muscle weakness and exposure to corticosteroids treatment, are generally considered to be at increased risk for osteoporosis or fracture. However, clinical evidence of this issue is lacking.
verfasst von:
Chien-Ju Lin, Yu-Shan Lee, Jiann-Horng Yeh, Shu-Jung Liu, Kuan-Yu Lin
Fragility fractures are associated with substantial pain, disability, reduced quality of life, and decreased life expectancy [ 1 , 2 ]. One in five men and one in two women over the age of 50 years will have a fragility fracture during their …
verfasst von:
Anum Ali, Ella Huszti, Shahryar Noordin, Usman Ali, Joanna E. M. Sale
Osteoporotic fractures are a major public health problem worldwide because they increase mortality and decrease quality of life [ 1 , 2 ]. In 2021, a systematic analysis from the Global Burden of Disease (GBD) Study provided the first estimate of …
Denosumab and bisphosphonates for primary osteoporosis are generally well-tolerated, but their comparative safety remains unclear. We aimed to explore the comparative safety of denosumab and bisphosphonates in primary osteoporosis. Databases such …
verfasst von:
Takaomi Kobayashi, Tadatsugu Morimoto, Koji Ito, Masaaki Mawatari, Takafumi Shimazaki
Osteoporosis is a bone disease that develops when bone mineral density (BMD) and bone mass decrease or when the structure and strength of bone change. This can increase susceptibility to fractures, especially in the hip, spine, and wrist [ 1 ].
Stroke is a leading cause of long-term disability worldwide [ 1 ]. Stroke is an important risk factor for fragility fractures, due to bone loss, immobilisation, gait disturbance, vitamin D deficiency, impaired balance and increased falls risk, [ 2 …
verfasst von:
Basil Liu, Chrislyn Yan Ng, Paul Bao Duy La, Phillip Wong, Peter R. Ebeling, Shaloo Singhal, Thanh Phan, Anne Trinh, Frances Milat
Osteoporosis (OP) is a systemic skeletal disease associated with low bone mineral density (BMD), microarchitectural deterioration, and an increased risk of fracture [ 1 ]. The estimated prevalence of OP in the US is 10.2 million with an additional …
verfasst von:
Deborah T. Gold, Tammy Beckett, Chad Deal, Andrew L. James, Mahshid Mohseni, Abigail McMillan, Tom Bailey, Leny Pearman, John Caminis, Yamei Wang, Setareh A. Williams, Jacqueline M. Kernaghan
Osteoporotic fractures are placing an unequivocal strain on healthcare systems globally in terms of cost and health-related quality of life. The annual incidence of new osteoporotic fractures alarmingly increased 23% from 3.5 million in 2010 to …
verfasst von:
Anitha D. Praveen, Thor Aspelund, Stephen J. Ferguson, Sigurður Sigurðsson, Vilmundur Guðnason, Halldór Pálsson, David Matchar, Benedikt Helgason
The global burden of osteoporosis continues to rise with an ageing population. Untreated osteoporotic fractures not only heighten the risk of subsequent fractures but are associated with excess mortality. Although primary care guidelines …
