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Journal of Bone and Mineral Metabolism


Journal of Bone and Mineral Metabolism OnlineFirst articles

27.09.2022 | Original Article

Clinical risk factors for severity and prognosis of antiresorptive agent-related osteonecrosis of the jaw: a retrospective observational study

Bisphosphonate (BP)-related osteonecrosis of the jaw impairs the quality of life of patients [ 1 ]. Similarly, denosumab (Dmab), an anti-receptor activator of NF-κB ligand antibody, causes osteonecrosis of the jaw and has a histopathological …

26.09.2022 | Original Article

Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage

Selenium (Se), as an essential trace element, is incorporated into selenoproteins in the form of the amino acid selenocysteine (Sec) which acts varieties of substrates and have multiple functions [ 1 ]. A plenty of documented evidence have …

26.09.2022 | Original Article

Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model

Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease caused by long-term inhalation of toxic substances, mainly cigarette smoke. It affects not only the lungs, but the entire body, and is a risk factor for osteoporosis and …

30.08.2022 | Invited Review

Wnt signaling: a double-edged sword in protecting bone from cancer

Wnt signaling plays a critical role in loading-driven bone formation and bone homeostasis, whereas its activation in cancer cells promotes their progression. Currently, major research efforts in cancer treatment have been directed to the …

30.08.2022 | Original Article

Strontium-89 plus zoledronic acid versus zoledronic acid for patients with painful bone metastatic breast cancer

Bone metastases occur in approximately 70% of patients with advanced breast cancer [ 1 ]. Of these patients, 65–75% suffer from intolerable pain [ 2 ]. Bone-modifying agents have played the most important roles in treating breast cancer patients …

Journal of Bone and Mineral Metabolism
Volume 15/1997 - Volume 40/2022
Springer Nature Singapore
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