Skip to main content
Erschienen in: Pediatric Surgery International 1/2023

01.12.2023 | Original Article

Predicting recurrent cases of intussusception in children after air enema reduction with machine learning models

verfasst von: Jing-yan Guo, Yu-feng Qian

Erschienen in: Pediatric Surgery International | Ausgabe 1/2023

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To develop a model to identify risk factors and predict recurrent cases of intussusception in children.

Methods

Consecutive cases and recurrent cases of intussusception in children from January 2016 to April 2022 were screened. The cohort was divided randomly at a 4:1 ratio to a training dataset and a validation dataset. Three parallel models were developed using extreme gradient boosting (XGBoost), logistic regression (LR), and support vector machine (SVM). Model performance was assessed by the area under the receiver operating characteristic curves (AUC).

Results

A total of 2469 cases of intussusception were included, where 225 were recurrent cases. The XGBoost (AUC = 0.718) models showed the best performance in the validation dataset, followed by the LR model (AUC = 0.652), while the SVM model (AUC = 0.613) performed worst among the three models. Based on the Shapley Additive exPlanation values, the most important variables in the XGBoost models were air enema pressure, mass size, age, duration of symptoms, and absence of vomiting.

Conclusions

Machine learning models, especially XGBoost, could be used to predict recurrent cases of intussusception in children. The most important contributing factors to the models are air enema pressure, mass size, age, duration of symptoms and absence of vomiting.
Literatur
1.
Zurück zum Zitat Niramis R, Watanatittan S, Kruatrachue A et al (2010) Management of recurrent intussusception: nonoperative or operative reduction? J Pediatr Surg 45(11):2175–2180CrossRefPubMed Niramis R, Watanatittan S, Kruatrachue A et al (2010) Management of recurrent intussusception: nonoperative or operative reduction? J Pediatr Surg 45(11):2175–2180CrossRefPubMed
2.
Zurück zum Zitat Cho MJ, Nam CW, Choi SH et al (2020) Management of recurrent ileocolic intussusception. J Pediatr Surg 55(10):2150–2153CrossRefPubMed Cho MJ, Nam CW, Choi SH et al (2020) Management of recurrent ileocolic intussusception. J Pediatr Surg 55(10):2150–2153CrossRefPubMed
3.
Zurück zum Zitat Chen X, Chen Q, Wang X et al (2021) Clinical characteristics of recurrent intussusception: a single-center retrospective study. J Pediatr Surg 56(10):1831–1834CrossRefPubMed Chen X, Chen Q, Wang X et al (2021) Clinical characteristics of recurrent intussusception: a single-center retrospective study. J Pediatr Surg 56(10):1831–1834CrossRefPubMed
4.
Zurück zum Zitat Guo WL, Wang J, Zhou M et al (2011) The role of plain radiography in assessing intussusception with vascular compromise in children. Arch Med Sci 7(5):877–881CrossRefPubMedPubMedCentral Guo WL, Wang J, Zhou M et al (2011) The role of plain radiography in assessing intussusception with vascular compromise in children. Arch Med Sci 7(5):877–881CrossRefPubMedPubMedCentral
5.
6.
Zurück zum Zitat Xie X, Wu Y, Wang Q et al (2018) Risk factors for recurrence of intussusception in pediatric patients: a retrospective study. J Pediatr Surg 53(11):2307–2311CrossRefPubMed Xie X, Wu Y, Wang Q et al (2018) Risk factors for recurrence of intussusception in pediatric patients: a retrospective study. J Pediatr Surg 53(11):2307–2311CrossRefPubMed
7.
Zurück zum Zitat Kourou K, Exarchos TP, Exarchos KP et al (2014) Machine learning applications in cancer prognosis and prediction. Comput Struct Biotechnol J13:8–17 Kourou K, Exarchos TP, Exarchos KP et al (2014) Machine learning applications in cancer prognosis and prediction. Comput Struct Biotechnol J13:8–17
9.
Zurück zum Zitat Ting X, Xufei D, Jiangbin L et al (2022) Development and validation of a nomogram for predicting pathological intussusceptions in children prior to surgical intervention. Front Pediatr 10:877358CrossRefPubMedPubMedCentral Ting X, Xufei D, Jiangbin L et al (2022) Development and validation of a nomogram for predicting pathological intussusceptions in children prior to surgical intervention. Front Pediatr 10:877358CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Tseng PY, Chen YT, Wang CH et al (2020) Prediction of the development of acute kidney injury following cardiac surgery by machine learning. Crit Care 24(1):478CrossRefPubMedPubMedCentral Tseng PY, Chen YT, Wang CH et al (2020) Prediction of the development of acute kidney injury following cardiac surgery by machine learning. Crit Care 24(1):478CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Goto T, Camargo CA Jr, Faridi MK et al (2018) Machine learning approaches for predicting disposition of asthma and COPD exacerbations in the ED. Am J Emerg Med 36:1650–1654CrossRefPubMed Goto T, Camargo CA Jr, Faridi MK et al (2018) Machine learning approaches for predicting disposition of asthma and COPD exacerbations in the ED. Am J Emerg Med 36:1650–1654CrossRefPubMed
12.
Zurück zum Zitat Goto T, Camargo CA Jr, Faridi MK et al (2019) Machine learning-based prediction of clinical outcomes for children during emergency department triage. JAMA Netw Open 2(1):e186937CrossRefPubMedPubMedCentral Goto T, Camargo CA Jr, Faridi MK et al (2019) Machine learning-based prediction of clinical outcomes for children during emergency department triage. JAMA Netw Open 2(1):e186937CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Yuan KC, Tsai LW, Lee KH et al (2020) The development an artificial intelligence algorithm for early sepsis diagnosis in the intensive care unit. Int J Med Inform 141:104176CrossRefPubMed Yuan KC, Tsai LW, Lee KH et al (2020) The development an artificial intelligence algorithm for early sepsis diagnosis in the intensive care unit. Int J Med Inform 141:104176CrossRefPubMed
14.
Zurück zum Zitat Xu L, Yang P, Liang W et al (2019) A radiomics approach based on support vector machine using MR images for preoperative lymph node status evaluation in intrahepatic cholangiocarcinoma. Theranostics 9(18):5374–5385CrossRefPubMedPubMedCentral Xu L, Yang P, Liang W et al (2019) A radiomics approach based on support vector machine using MR images for preoperative lymph node status evaluation in intrahepatic cholangiocarcinoma. Theranostics 9(18):5374–5385CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Zhang Y, Shao CC, Wei XL et al (2022) Ultrasound findings to predict risk of recurrence in pediatric intussusception after air enema reduction. J Ultrasound Med 41(5):1227–1235CrossRefPubMed Zhang Y, Shao CC, Wei XL et al (2022) Ultrasound findings to predict risk of recurrence in pediatric intussusception after air enema reduction. J Ultrasound Med 41(5):1227–1235CrossRefPubMed
16.
Zurück zum Zitat Kim JH, Lee JS, Ryu JM et al (2018) Risk factors for recurrent intussusception after fluoroscopy–guided air enema. Pediatr Emerg Care 34(7):484–487CrossRefPubMed Kim JH, Lee JS, Ryu JM et al (2018) Risk factors for recurrent intussusception after fluoroscopy–guided air enema. Pediatr Emerg Care 34(7):484–487CrossRefPubMed
17.
Zurück zum Zitat Shen G, Zhang C, Li J, Zhang J et al (2018) Risk factors for short-term recurrent intussusception and reduction failure after ultrasound-guided saline enema. Pediatr Surg Int 34(11):1225–1231CrossRefPubMed Shen G, Zhang C, Li J, Zhang J et al (2018) Risk factors for short-term recurrent intussusception and reduction failure after ultrasound-guided saline enema. Pediatr Surg Int 34(11):1225–1231CrossRefPubMed
18.
Zurück zum Zitat Wang Z, He QM, Zhang H et al (2015) Intussusception patients older than 1 year tend to have early re-currence after pneumatic enema reduction. Pediatr Surg Int 31(9):855–858CrossRefPubMed Wang Z, He QM, Zhang H et al (2015) Intussusception patients older than 1 year tend to have early re-currence after pneumatic enema reduction. Pediatr Surg Int 31(9):855–858CrossRefPubMed
19.
Zurück zum Zitat Justice FA, Nguyen LT, Tran SN et al (2011) Recurrent intussusception in infants. J Paediatr Child Health 47:802–805CrossRefPubMed Justice FA, Nguyen LT, Tran SN et al (2011) Recurrent intussusception in infants. J Paediatr Child Health 47:802–805CrossRefPubMed
20.
Zurück zum Zitat Champoux AN, Del Beccaro MA, Nazar-Stewart V (1994) Recurrent intussusception. Risks and features. Arch Pediatr Adolesc Med 148:474–478CrossRefPubMed Champoux AN, Del Beccaro MA, Nazar-Stewart V (1994) Recurrent intussusception. Risks and features. Arch Pediatr Adolesc Med 148:474–478CrossRefPubMed
21.
Zurück zum Zitat Lin XK, Xia QZ, Huang XZ et al (2017) Clinical characteristics of intussusception secondary to pathologic lead points in children: a single-center experience with 65 cases. Pediatr Surg Int 33(7):793–797CrossRefPubMed Lin XK, Xia QZ, Huang XZ et al (2017) Clinical characteristics of intussusception secondary to pathologic lead points in children: a single-center experience with 65 cases. Pediatr Surg Int 33(7):793–797CrossRefPubMed
Metadaten
Titel
Predicting recurrent cases of intussusception in children after air enema reduction with machine learning models
verfasst von
Jing-yan Guo
Yu-feng Qian
Publikationsdatum
01.12.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Surgery International / Ausgabe 1/2023
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-022-05309-6

Weitere Artikel der Ausgabe 1/2023

Pediatric Surgery International 1/2023 Zur Ausgabe

Neuer Typ-1-Diabetes bei Kindern am Wochenende eher übersehen

23.04.2024 Typ-1-Diabetes Nachrichten

Wenn Kinder an Werktagen zum Arzt gehen, werden neu auftretender Typ-1-Diabetes und diabetische Ketoazidosen häufiger erkannt als bei Arztbesuchen an Wochenenden oder Feiertagen.

Neue Studienergebnisse zur Myopiekontrolle mit Atropin

22.04.2024 Fehlsichtigkeit Nachrichten

Augentropfen mit niedrig dosiertem Atropin können helfen, das Fortschreiten einer Kurzsichtigkeit bei Kindern zumindest zu verlangsamen, wie die Ergebnisse einer aktuellen Studie mit verschiedenen Dosierungen zeigen.

Spinale Muskelatrophie: Neugeborenen-Screening lohnt sich

18.04.2024 Spinale Muskelatrophien Nachrichten

Seit 2021 ist die Untersuchung auf spinale Muskelatrophie Teil des Neugeborenen-Screenings in Deutschland. Eine Studie liefert weitere Evidenz für den Nutzen der Maßnahme.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

Update Pädiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.