Introduction
Methods
Study population
Interventions and outcomes
Specimens analysis
Statistical analysis
Results
Group division
Variables | Postoperative complications | P value | |
---|---|---|---|
Yes (N = 10) | No (N = 12) | ||
MMP1 | 5.99 (− 0.44–11.79) | 9.16 (2.96–13.06) | 0.539 |
MMP2 | 2.83 (0.75–4.63) | 2.00 (0.80–3.05) | 0.080 |
MMP9 | 5.77 (3.19–11.11) | 3.32 (2.04–4.85) | 0.002 |
TIMP1 | 1.53 (− 1.10–2.98) | 0.81 (− 0.54–2.55) | 0.180 |
Variables | MMP9-low group (N = 11) | MMP9-high group (N = 11) | P value |
---|---|---|---|
Gender | |||
Male | 11 (100%) | 11 (100%) | |
Age, years | 70 (54–80) | 73 (54–80) | 0.270 |
Etiology | – | ||
Tuberculosis | 11 (100%) | 11 (100%) | |
Preoperative NYHA functional class | 0.327 | ||
I | 2 (18.2%) | 0 (0%) | |
II | 1 (9.1%) | 3 (27.3%) | |
III | 8 (72.7%) | 8 (72.7%) | |
Hypertension | 1 (9.1%) | 2 (18.2%) | 1.000 |
Diabetes | 2 (18.2%) | 2 (18.2%) | 1.000 |
Heart disease* | 2 (18.2%) | 4 (36.4%) | 0.635 |
BMI, kg/m2 | 21.3 (17.3–24.8) | 21.0 (17.7–24.8) | 0.652 |
Pulse rate, beats/min | 98 (80–112) | 90 (80–145) | 0.699 |
Preoperative CVP, cmH2O | 23.0 (20.5–30.0) | 30.0 (20.4–42.5) | 0.065 |
Pericardial thickness, mm | 10.7 (8.2–16.0) | 10.7 (7.0–16.0) | 0.847 |
LVEF, % | 54.3 (50.0–56.4) | 56.0 (51.9–64.0) | 0.101 |
CRP, mg/L | 11.7 (5.0–21.0) | 17.0 (5.0–62.5) | 0.076 |
ESR, mm/h | 37.0 (3.0–52.0) | 37.0 (17.0–68.0) | 0.300 |
Postoperative outcomes
Variables | MMP9-low group (N = 11) | MMP9-high group (N = 11) | P value |
---|---|---|---|
Postoperative CVP, cmH2O | 17.0 (5.0–20.0) | 17.8 (5.0–32.0) | 0.365 |
Postoperative intubation, h | 11 (3–132) | 28 (5–232) | 0.173 |
Duration of using vasoactive agents, h | 0 (0–116) | 47 (0–143) | 0.114 |
Postoperative complications | 1 (9.1%) | 9 (81.8%) | 0.002 |
Postoperative ICU stay, days | 2 (1–5) | 4.5 (1–10) | 0.040 |
Postoperative hospital stay, days | 18 (13–24) | 23 (13–29) | 0.043 |
In-hospital mortality | 0 (0%) | 1 (9.1%) | 1.000 |
Multivariate analysis
Groups | Postoperative complications | ||
---|---|---|---|
OR | 95%CI | P value | |
MMP9-low group | 1 | – | – |
MMP9-high group | 27.096 | 1.166–629.886 | 0.040 |