Background
Methods
Participants
Measures
Medical tests
Cardiorespiratory fitness
Leg extension power
Determination of diabetes
Statistics analysis
Results
Characteristics of the study participants
Total (n = 796) | Diabetes (n = 55) | No diabetes (n = 741) | |
---|---|---|---|
Age (years) | 56.5 ± 10.4 | 64.0 ± 9.1 | 55.9 ± 10.2 |
Height (cm) | 170.3 ± 5.8 | 169.3 ± 5.0 | 170.4 ± 5.8 |
Weight (kg) | 68.7 ± 9.7 | 69.7 ± 10.8 | 68.6 ± 9.7 |
Waist circumference (cm) | 84.5 ± 8.6 | 87.7 ± 9.0 | 84.3 ± 8.5 |
Calf circumference (cm) | 37.5 ± 2.6 | 37.3 ± 3.2 | 37.5 ± 2.5 |
Body mass index (kg/m2) | 23.7 ± 3.0 | 24.3 ± 3.4 | 23.6 ± 3.0 |
Percent body fat (%) | 20.5 ± 5.8 | 23.2 ± 5.3 | 20.3 ± 5.8 |
Systolic blood pressure (mmHg) | 132.0 ± 18.8 | 139.3 ± 20.9 | 131.4 ± 18.5 |
Diastolic blood pressure (mmHg) | 83.5 ± 11.6 | 84.1 ± 13.3 | 83.4 ± 11.4 |
Grip strength (kg) | 36.8 ± 5.7 | 34.4 ± 6.2 | 37.0 ± 5.6 |
Relative grip strength, (kg/kg) | 0.54 ± 0.09 | 0.50 ± 0.08 | 0.55 ± 0.09 |
Leg extension power (W) | 1278 ± 368 | 1088 ± 348 | 1292 ± 366 |
Relative leg extension power (W/kg) | 18.6 ± 4.8 | 15.5 ± 3.9 | 18.9 ± 4.8 |
Peak oxygen uptake (mL/kg/min) | 30.3 ± 6.4 | 26.1 ± 4.6 | 30.6 ± 6.4 |
Total cholesterol (mg/dL) | 209.9 ± 34.1 | 202.4 ± 33.6 | 210.4 ± 34.1 |
HDL cholesterol (mg/dL) | 61.9 ± 16.0 | 57.7 ± 18.2 | 62.2 ± 15.8 |
LDL cholesterol (mg/dL) | 122.9 ± 29.8 | 118.2 ± 29.8 | 123.2 ± 29.8 |
Triglycerides (mg/dL)a | 87.0 (62.0 − 127.0) | 95.0 (68.0 − 151.0) | 87.0 (61.0 − 126.5) |
Fasting glucose (mg/dL) | 98.2 ± 14.5 | 133.4 ± 25.9 | 95.6 ± 8.8 |
HbA1c (%) | 5.5 ± 0.5 | 6.7 ± 0.7 | 5.4 ± 0.3 |
Exercise habit (%) | 541 (68.0) | 42 (76.4) | 499 (67.3) |
Hypertension (%) | 188 (23.6) | 20 (36.4) | 168 (22.7) |
Dyslipidemia (%) | 205 (25.8) | 24 (43.6) | 181 (24.4) |
Family history of diabetes (%) | 182 (22.9) | 20 (36.4) | 162 (21.9) |
Family history of hypertension (%) | 350 (44.0) | 26 (47.3) | 324 (43.7) |
Family history of dyslipidemia, (%) | 82 (10.3) | 6 (10.9) | 76 (10.3) |
Current smokers (%) | 63 (7.9) | 7 (12.7) | 56 (7.6) |
Non-drinkers (%) | 103 (12.9) | 10 (18.2) | 93 (12.6) |
Low CRF & Low rLEP (n = 269) | Low CRF & High rLEP (n = 129) | High CRF & Low rLEP (n = 129) | High CRF & High rLEP (n = 269) | |
---|---|---|---|---|
Age (years) | 63.1 ± 9.8 | 56.6 ± 9.1 | 55.6 ± 9.3 | 50.1 ± 7.5 |
Height (cm) | 169.6 ± 6.0 | 170.5 ± 5.9 | 170.5 ± 5.9 | 171.0 ± 5.4 |
Weight (kg) | 71.2 ± 11.0 | 69.5 ± 8.4 | 66.6 ± 8.7 | 66.8 ± 8.8 |
Waist circumference (cm) | 89.1 ± 8.7 | 85.3 ± 7.0 | 81.9 ± 7.5 | 80.8 ± 7.3 |
Calf circumference (cm) | 37.7 ± 2.9 | 37.4 ± 2.6 | 37.5 ± 2.4 | 37.4 ± 2.3 |
Body mass index (kg/m2) | 24.7 ± 3.4 | 23.9 ± 2.9 | 22.9 ± 2.6 | 22.8 ± 2.5 |
Percent body fat (%) | 23.9 ± 5.5 | 20.8 ± 4.8 | 18.4 ± 5.1 | 18.0 ± 5.0 |
Systolic blood pressure (mmHg) | 138.6 ± 19.9 | 133.4 ± 17.3 | 129.3 ± 17.2 | 125.9 ± 16.8 |
Diastolic blood pressure (mmHg) | 85.6 ± 12.1 | 85.6 ± 11.0 | 81.9 ± 9.9 | 81.1 ± 11.4 |
Grip strength (kg) | 34.7 ± 5.8 | 38.0 ± 5.9 | 36.4 ± 4.5 | 38.7 ± 5.3 |
Relative grip strength, (kg/kg) | 0.49 ± 0.08 | 0.55 ± 0.10 | 0.55 ± 0.07 | 0.58 ± 0.08 |
Leg extension power (W) | 1033 ± 273 | 1484 ± 273 | 1041 ± 222 | 1537 ± 305 |
Relative leg extension power (W/kg) | 14.4 ± 2.8 | 21.3 ± 2.3 | 15.6 ± 2.5 | 23.0 ± 3.4 |
Peak oxygen uptake (mL/kg/min) | 24.7 ± 3.0 | 26.4 ± 2.5 | 33.5 ± 3.3 | 36.1 ± 5.2 |
Total cholesterol (mg/dL) | 209.2 ± 36.1 | 208.5 ± 32.8 | 212.1 ± 31.8 | 210.3 ± 33.8 |
HDL cholesterol (mg/dL) | 58.5 ± 14.9 | 59.1 ± 13.1 | 66.2 ± 16.9 | 64.5 ± 16.9 |
LDL cholesterol (mg/dL) | 124.0 ± 31.9 | 121.6 ± 28.3 | 123.4 ± 29.7 | 122.1 ± 28.6 |
Triglycerides (mg/dL)a | 99.0 (69.0 − 141.0) | 103.0 (73.0 − 151.5) | 77.0 (55.0 − 106.0) | 79.0 (55.5 − 114.0) |
Fasting glucose (mg/dL) | 102.7 ± 16.9 | 97.4 ± 12.1 | 95.6 ± 13.0 | 95.3 ± 12.3 |
HbA1c (%) | 5.6 ± 0.6 | 5.5 ± 0.5 | 5.4 ± 0.4 | 5.3 ± 0.4 |
Exercise habit (%) | 158 (58.7) | 79 (61.2) | 99 (76.7) | 205 (76.2) |
Hypertension (%) | 105 (39.0) | 29 (22.5) | 29 (22.5) | 25 (9.3) |
Dyslipidemia (%) | 80 (29.7) | 38 (29.5) | 36 (27.9) | 51 (19.0) |
Family history of diabetes (%) | 66 (24.5) | 30 (23.3) | 24 (18.6) | 62 (23.0) |
Family history of hypertension (%) | 128 (47.6) | 59 (45.7) | 56 (43.4) | 107 (39.8) |
Family history of dyslipidemia (%) | 28 (10.4) | 13 (10.1) | 12 (9.3) | 29 (10.8) |
Current smokers (%) | 21 (7.8) | 13 (10.1) | 11 (8.5) | 18 (6.7) |
Non-drinkers (%) | 37 (13.8) | 20 (15.5) | 13 (10.1) | 33 (12.3) |
Diabetes (%) | 38 (14.1) | 5 (3.9) | 7 (5.4) | 5 (1.9) |
Diabetes prevalence by CRF and rLEP
n | Cases | Cases per 1000 | Unadjusted OR (95% CI) | Age-adjusted OR (95% CI) | Multivariable-adjusted ORa (95% CI) | |
---|---|---|---|---|---|---|
Cardiorespiratory fitness | ||||||
Low cardiorespiratory fitness | 398 | 43 | 108 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
High cardiorespiratory fitness | 398 | 12 | 30 | 0.26 (0.13 − 0.50) | 0.45 (0.22 − 0.92) | 0.46 (0.21 − 0.98) |
Relative leg extension power | ||||||
Low relative leg extension power | 398 | 45 | 113 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
High relative leg extension power | 398 | 10 | 25 | 0.20 (0.10 − 0.41) | 0.33 (0.16 − –0.69) | 0.34 (0.16 − 0.74) |
Diabetes prevalence by the combination of CRF and rLEP
n | Cases | Cases per 1000 | Unadjusted OR (95% CI) | Age-adjusted OR (95% CI) | Multivariable-adjusted ORa (95% CI) | |
---|---|---|---|---|---|---|
Low CRF & Low rLEP | 269 | 38 | 141 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
Low CRF & High rLEP | 129 | 5 | 39 | 0.25 (0.09 − 0.64) | 0.33 (0.12 − 0.88) | 0.32 (0.12 − 0.88) |
High CRF & Low rLEP | 129 | 7 | 54 | 0.35 (0.15 − 0.80) | 0.49 (0.21 − 1.18) | 0.46 (0.18 − 1.16) |
High CRF & High rLEP | 269 | 5 | 19 | 0.12 (0.05 − 0.30) | 0.22 (0.08 − 0.61) | 0.21 (0.07 − 0.63) |